Clinical trials: Disease, Hodgkin
Non-Hodgkin's Lymphoma, Burkitt Lymphoma
Pegylated Liposomal Doxorubicin (Doxil) With Rituximab in Relapsed AIDS-Related Non-Hodgkin's Lymphomas
This study is for patients who have been treated before and either the treatment did not work or the lymphoma has come back.
- Conditions
- Non-Hodgkin's Lymphoma, Burkitt Lymphoma, Primary Effusion Lymphomas
- Trial name
- NCT00183976
- Testing
- Pegylated Liposomal Doxorubicin (Doxil) and Rituximab
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Southern California
Mantle Cell Lymphoma
A Phase II Study to Evaluate Efficacy and Safety of P276-00 in Relapsed and/or Refractory Mantle Cell Lymphoma
The purpose of this study is to determine whether P276-00 is safe and effective in treatment of Mantle Cell Lymphoma that is recurred after or not responding to at least one previous line of treatment.
- Trial name
- NCT00843050
- Testing
- P276-00
- Where
- 20 sites in United States, India
- Volunteers
- 13 people
- Sponsor
- Piramal Enterprises Limited
Leukemia, Lymphoma
Effect of Tight Control of Blood Glucose During Hyper-CVAD Chemotherapy For Acute Lymphocytic Leukemia (ALL)
The goal of this clinical research study is to learn if intense management and control of blood sugar levels during treatment for acute lymphocytic leukemia, Burkitts lymphoma, or lymphoblastic lymphoma will result in decreased…
- Trial name
- NCT00500240
- Testing
- Insulin Glargine, Insulin Aspart
- Where
- United States
- Volunteers
- 52 people
- Sponsor
- M.D. Anderson Cancer Center
Cutaneous T-Cell Non-Hodgkin Lymphoma, Recurrent Mycosis Fungoides and Sezary Syndrome
Reduced Intensity Conditioning Before Partially Matched Donor Stem Cell Transplant in Treating Patients With Advanced Cutaneous T Cell Lymphoma
This phase I trial studies the side effects and the best dose of donor lymphocyte infusion when given together with reduced intensity conditioning regimen before partially matched donor stem cell transplant in treating patients…
- Conditions
- Cutaneous T-Cell Non-Hodgkin Lymphoma, Recurrent Mycosis Fungoides and Sezary Syndrome, Stage IIB Mycosis Fungoides and Sezary Syndrome, Stage IIIA Mycosis Fungoides and Sezary Syndrome
- Trial name
- NCT02548468
- Testing
- Fludarabine, Total-Body Irradiation, T Cell-Depleted Donor Lymphocyte Infusion
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University
Classical Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma
Immune Responses to COVID-19 Vaccination in Lymphoma Patients
This prospective observational study aims to evaluate the robustness and persistence of immune responses to vaccination, define factors associated with impaired immune responses and assess the incidence of COVID-19 infections in…
- Conditions
- Classical Hodgkin Lymphoma, Diffuse Large B Cell Lymphoma, Primary Mediastinal B Cell Lymphoma, High-grade B-cell Lymphoma
- Trial name
- PROSECO (NCT04858568)
- Where
- 9 sites in United Kingdom
- Volunteers
- 592 people
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Lymphoma, Mantle-Cell
Rituximab, Bendamustine and Cytarabine Followed by Venetoclax in High Risk Elderly Patients With MCL
Prospective, multicenter, phase II trial designed to evaluate whether the addition of Venetoclax after rituximab, bendamustine and cytarabine (R-BAC) to high risk patients with mantle cell lymphoma improves the results of the…
- Trial name
- NCT03567876
- Testing
- Venetoclax
- Where
- 35 sites in Italy
- Volunteers
- 141 people
- Sponsor
- Fondazione Italiana Linfomi - ETS
Mantle Cell Lymphoma
Phase I Study of Panobinostat + Bortezomib for Relapsed and/or Refractory Mantle Cell Lymphoma (MCL)
The purpose of this study is to determine the safety and clinical efficacy of the combination of panobinostat plus bortezomib.
- Trial name
- BUS48T (NCT01504776)
- Testing
- Panobinostat, Bortezomib
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- Anand Jillella
Lymphoma
A Study of PCI-32765 (Ibrutinib) in Combination With Either Bendamustine and Rituximab or Rituximab, Cyclophosphamide, Doxorubicin, Vincristine, and Prednisone in Participants With Previously Treated Indolent Non-Hodgkin Lymphoma
The purpose of this study is to evaluate the efficacy and safety of PCI-32765 (ibrutinib) administered in combination with either bendamustine and rituximab (BR) or rituximab, cyclophosphamide, doxorubicin, vincristine, and…
- Trial name
- SELENE (NCT01974440)
- Testing
- Bendamustine, Rituximab, Cyclophosphamide
- Where
- 135 sites in United States, Argentina and 17 more
- Volunteers
- 403 people
- Sponsor
- Janssen Research & Development, LLC
Diffuse Large B-cell Lymphoma
Chidamide in Patients With Recurrent and Refractory Diffuse Large b
A Multicenter, Prospective, Observational Clinical Protocol for Chidamide in Combination With Rituximab and Lenalidomide (cR2) in Real-world Practice in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma
- Trial name
- NCT05690191
- Testing
- Chidamide, Lenalidomide, Rituximab
- Where
- China
- Volunteers
- 169 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Follicular Lymphoma
Rituximab Therapy in Follicular Lymphoma in Combination With Chemotherapy - REFLECT 1
The primary objective is to evaluate the safety profile and tolerability of rituximab in combination with different chemotherapy regimens.
- Trial name
- NCT02461290
- Testing
- Chemotherapy, Rituximab
- Where
- 6 sites in Serbia
- Volunteers
- 99 people
- Sponsor
- Hoffmann-La Roche
Survivorship, Quality of Life
Neuromodulation of Central Sensory Integration to Improve Postural Control
The objective is to evaluate if neuromodulation of the PFC can acutely improve sensory integration for balance performance in OTTBCS.
- Conditions
- Survivorship, Quality of Life, Cognitive Deficits, Mild
- Trial name
- NCT06610617
- Testing
- transcranial direct current stimulation (tDCS)
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Pittsburgh
Peripheral T-cell Lymphoma
A Study of TQ-B3525 in Subjects With Relapsed/Refractory Peripheral T-cell Lymphoma（PTCL）
This is a study to evaluate the efficacy and safety of TQ-B3525 in subjects with relapse/refactory peripheral T-cell lymphoma who have received at least 1 lines of therapeutic schedules.
- Trial name
- NCT04615468
- Testing
- TQ-B3525
- Where
- 2 sites in China
- Volunteers
- 78 people
- Sponsor
- Chia Tai Tianqing Pharmaceutical Group Co., Ltd.
Hodgkin Lymphoma, Advanced Hodgkin Lymphoma
BrECADD Therapy in Stage 2 B-IV Hodgkin Lymphoma
The purpose of this study is to further assess the efficacy and tolerability of a regimen of Brentuximab Vedotin, Etoposide, Cyclophosphamide, Doxorubicin, Dacarbazine, and Dexamethasone (BrECADD) in patients with Stage 2 B-IV…
- Trial name
- BrECADD (NCT07002216)
- Testing
- Brentuximab Vedotin, Etoposide, Cyclophosphamide
- Where
- United States
- Volunteers
- 48 people
- Sponsor
- University of Miami
Acute Biphenotypic Leukemia, Acute Erythroid Leukemia in Remission
Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies
This phase II trial studies how well donor peripheral blood stem cell (PBSC) transplant works in treating patients with hematologic malignancies.
- Conditions
- Acute Biphenotypic Leukemia, Acute Erythroid Leukemia in Remission, Acute Leukemia in Remission, Acute Lymphoblastic Leukemia in Remission
- Trial name
- NCT01028716
- Testing
- Cyclophosphamide, Filgrastim, Fludarabine Phosphate
- Where
- United States
- Volunteers
- 46 people
- Sponsor
- Fred Hutchinson Cancer Center
Acute Lymphocytic Leukemia, Diffuse Large Cell Lymphoma
Pilot Study of Redirected Autologous T Cells Engineered to Contain Humanized Anti-CD19 in Patients With Relapsed or Refractory CD19+ Leukemia and Lymphoma Previously Treated With Cell Therapy
This is a pilot study to evaluate humanized CD19 redirected autologous T cells (or huCART19 cells) in patients with relapsed or refractory CD19+ leukemia and lymphoma that was previously treated with cell therapy.
- Trial name
- NCT02374333
- Testing
- huCART19
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- University of Pennsylvania
Classic Hodgkin Lymphoma
Liposomal Doxorubicin-containing Front-line Treatment in Elderly Patients With HL (HL-MVD)
Study on the use of a polychemotherapy scheme based on liposomal doxorubicin, vinblastine and dacarbazine (MVD) as first line in the therapy of elderly patients affected by classic Hodgkin lymphoma
- Trial name
- NCT06235047
- Where
- Italy
- Volunteers
- 60 people
- Sponsor
- Federico II University
AIDS-related Peripheral/Systemic Lymphoma, AIDS-related Primary CNS Lymphoma
Radiolabeled Monoclonal Antibody With or Without Peripheral Stem Cell Transplantation in Treating Children With Recurrent or Refractory Lymphoma
Phase I trial to study the effectiveness of radiolabeled monoclonal antibody therapy with or without peripheral stem cell transplantation in treating patients who have recurrent or refractory lymphoma.
- Conditions
- AIDS-related Peripheral/Systemic Lymphoma, AIDS-related Primary CNS Lymphoma, Post-transplant Lymphoproliferative Disorder, Recurrent Childhood Large Cell Lymphoma
- Trial name
- NCT00036855
- Testing
- rituximab, indium In 111 ibritumomab tiuxetan, yttrium Y 90 ibritumomab tiuxetan
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- National Cancer Institute (NCI)
Lymphoma, Lymphoma, Large B-Cell, Diffuse, Non-Hodgkin's Lymphoma, Lymphoma, Non Hodgkin, Relapsed or Refractory Diffuse Large B-Cell Lymphoma
MabThera (Rituximab) in Combination With CHOP (or CHOP-like) Chemotherapy in Patients With Aggressive B-Cell Lymphoma
Evaluation of efficacy, safety profile and tolerability of rituximab (MabThera) in combination with chemotherapy in the treatment of Diffuse Large B-Cell Lymphoma (DLBCL).
- Trial name
- NCT02486952
- Testing
- Cyclophosphamide, Hydroxydaunorubicin, Oncovin
- Where
- 5 sites in Serbia
- Volunteers
- 154 people
- Sponsor
- Hoffmann-La Roche
Diffuse Large B Cell Lymphoma, Central Nervous System Metastasis
ctDNA and Metabolites in CSF as Early Biomarkers of Secondary CNS Involvement in Diffuse Large B-cell Lymphoma
The study is a prospective clinical study which investigates the use of new diagnostic methods to localize aggressive lymphoma involving the central nervous system(CNS).
- Trial name
- CNSctDNA (NCT04112238)
- Where
- Denmark
- Volunteers
- 75 people
- Sponsor
- Herlev Hospital
Asthma
Airway Remodeling During Mepolizumab Treatment
Chronic airway changes, such as smooth muscle hypertrophy/hyperplasia, reticular basement membrane (RBM) thickening, goblet cells hyperplasia characterize severe asthma.
- Trial name
- REMOMEPO (NCT03797404)
- Where
- France
- Volunteers
- 37 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
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