Clinical trials: Disease Progression
Myopia
Influence of Rodenstock Spectacle Lenses on Myopia Progression.
The prevalence of myopia in Singapore is among the highest in the world, with 65 percent of our children being myopic by Primary 6, and 83 percent of young adults being myopic.
- Trial name
- NCT06816446
- Testing
- Myopia control spectacle lens, Single-vision lens
- Where
- Singapore
- Volunteers
- 185 people, healthy volunteers welcome
- Sponsor
- Rodenstock GmbH
Parkinson Disease, Genetic Disease
The Epidemiology of Parkinson's Disease in Croatia and the Influence of Genetic Factors and Microbiota on the Progression and Treatment Outcomes of the Disease (GiOPARK)
Parkinson's disease (PD) is the second most common neurodegenerative disease, which affects 2-3% of the general population above 65 years.
- Conditions
- Parkinson Disease, Genetic Disease, Microbiota, Neuro-Degenerative Disease
- Trial name
- GiOPARK (NCT05008094)
- Testing
- Whole-exome sequencing, Microbiota sequencing, Magnetic resonance imaging
- Where
- Croatia
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Clinical Hospital Center Rijeka
Episodic Migraine, Chronic Daily Migraine
fMRI of the Brainstem in Migraine Sufferers and Controls. Does Iron Deposition Correlate With Progression of Disease?
This is a 2 visit research study for patients with or without a diagnosis of migraine. Participants will be administered informed consent, have a medical history taken and a physical examination performed, and complete 3…
- Trial name
- NCT00868556
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- The Cleveland Clinic
Myopia, Myopia, Progressive
Multicenter RCT: LED Red Light Dose-Response in Myopia Progression Control
The goal of this clinical trial is to verify the effectiveness and safety of non-laser LED red light combined with defocus lens therapy for controlling myopia progression and evaluate the impact of different intervention…
- Trial name
- NCT07330180
- Testing
- Yingtong Vision Rehabilitation Instrument, Hoya DIMS multi-point myopia defocus lens
- Where
- 7 sites in China
- Volunteers
- 364 people, healthy volunteers welcome
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Adolescent Idiopathic Scoliosis, Idiopathic Scoliosis
Adolescent Idiopathic Scoliosis and Proprioceptive Defect
This is the first clinical study to examine the spinal and peripheral proprioceptive deficits in longitudinal terms among subjects with adolescent idiopathic scoliosis.
- Conditions
- Adolescent Idiopathic Scoliosis, Idiopathic Scoliosis, Scoliosis
- Trial name
- NCT04682379
- Testing
- Proprioceptive assessment
- Where
- Hong Kong
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Mild Cognitive Impairment, Obstructive Sleep Apnea
Evaluation of Trazodone in OSA-MCI
Alzheimer's disease (AD) is a progressive and multifactorial neurodegenerative disease. Before progressing to AD, individuals may experience mild cognitive impairment (MCI).
- Trial name
- NCT05209035
- Testing
- Trazodone
- Where
- Hong Kong
- Volunteers
- 134 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Colorectal Neoplasms, Colorectal Cancer
Bile Acids and Microbiome in Early Colorectal Carcinogenesis
Currently colorectal cancer pathogenesis is mainly explained by the adenoma-carcinoma sequence theory that was proposed more than half a century ago.
- Conditions
- Colorectal Neoplasms, Colorectal Cancer, Colorectal Polyp, Microbiome
- Trial name
- NCT06502704
- Where
- Lithuania
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vilnius University
Labor; Prolonged, Second Stage, Delivery Problem
Maternal Position's Effect on Labor Progression in Occiput Posterior Deliveries
This is a randomized controlled experimental study to determine the effect of maternal position on the progression of labour in deliveries in which the foetus is in the occiput posterior position.
- Trial name
- NCT06928038
- Testing
- Positioned group
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Biruni University
Atherosclerosis
Progression of Early Subclinical Atherosclerosis
The overall objective of this study is to characterize the prevalence and progression rate of subclinical atherosclerotic lesions and to study their association to the imaging characteristics of atheroma plaques and to the…
- Trial name
- PESA (NCT01410318)
- Where
- Spain
- Volunteers
- 4,184 people, healthy volunteers welcome
- Sponsor
- Fundación Centro Nacional de Investigaciones Cardiovasculares Carlos III