Clinical trials: Disease Severity
Adolescent Idiopathic Scoliosis (AIS), Back Pain
Impact of Curve Magnitude on Pain and Body Image in Patients With Adolescents Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional spinal deformity characterized by lateral curvature and rotation of the spine.
- Conditions
- Adolescent Idiopathic Scoliosis (AIS), Back Pain, Back Pain Lower Back, Body Image
- Trial name
- AIS (NCT07405112)
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Antalya Training and Research Hospital
Polycystic Ovary Syndrome
High Intensity Interval Training or Strength Training in Women With Polycystic Ovary Syndrome
The aim is to investigate whether strength training or high intensity interval training is effective in improving insulin sensitivity, cardiovascular outcomes, body composition and reproductive outcomes in women with Polycystic…
- Trial name
- NCT01919281
- Testing
- strength training, interval training
- Where
- Norway
- Volunteers
- 31 people
- Sponsor
- Norwegian University of Science and Technology
Coronary Stenosis
Saline-induced Distal to Aortic Coronary Pressure Ratio vs. Resting and Hyperemic Indices of Coronary Artery Stenosis Severity
The presence of inducible myocardial ischemia is considered as the prerequisite for the clinical benefit of coronary revascularization.
- Trial name
- SALINE (NCT04284345)
- Testing
- Saline Pd/Pa
- Where
- Switzerland
- Volunteers
- 90 people
- Sponsor
- University Hospital, Geneva
Cognitive Decline
Manipulating Cognitive Intensity During Aerobic Exercise
The purpose of this study is to investigate the performance effects of manipulating the properties of a cognitively engaging aerobic task.
- Trial name
- NCT06479265
- Testing
- Phyical/Cognitve Exercise
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- University of Southern California
High Intensity Interval Training, Continuous Running
Recovery Following Acute Endurance Training
Aerobic capacity is critical for many athletes, especially for endurance athletes. Althgough several training methods are implemented by coaches to improve endurance performance, recovery following acute endurance training is not…
- Conditions
- High Intensity Interval Training, Continuous Running, Control Condition
- Trial name
- ETRec (NCT06043492)
- Testing
- High Intensity Interval Training, Coninuous Running, Control Trial
- Where
- Greece
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Thessaly
Nicotine Addiction
Non-Invasive Deep Brain Neuromodulation for Smoking Cessation
This study will develop novel low intensity focused ultrasound (LIFU) therapy to help people to quit cigarette smoking. Smoking is associated with cancers of the lung. Available smoking cessation methods help many to quit.
- Trial name
- NCT07298902
- Testing
- Low intensity focused ultrasound with active stimulations
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center, Houston
COVID-19 Infection
Efficacy of Intranasal Probiotic Treatment to Reduce Severity of Symptoms in COVID19 Infection
Randomised, single-blinded trial. Patients with a diagnosis of COVID-19 infection within the past 96 hours and not requiring hospitalization will be recruited into a trial of BID Nasal irrigation for 14 days, followed by a 14 day…
- Trial name
- NCT04458519
- Testing
- Probiorinse, Saline solution
- Where
- Canada
- Volunteers
- 23 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Placenta Accreta
Feasibility of HIFU for Management of Placenta Accreta (HIFU-ACCRETA)
Placental accretion during pregnancy refers to an abnormally deep insertion of the placenta into the uterus, leading to the impossibility of removing the placenta without inducting uterine or surrounding organs lesions.
- Trial name
- HIFU-ACCRETA (NCT04003428)
- Testing
- High Intensity Focused Ultrasound
- Sponsor
- Hospices Civils de Lyon
Acute Myeloid Leukemia in Remission, Primary Myelofibrosis
Ruxolitinib Phosphate, Tacrolimus and Sirolimus in Preventing Acute Graft-versus-Host Disease During Reduced Intensity Donor Hematopoietic Cell Transplant in Patients With Myelofibrosis
This phase I trial studies the side effects and best dose of ruxolitinib phosphate when given together with tacrolimus and sirolimus in preventing acute graft-versus-host disease during reduced intensity donor hematopoietic cell…
- Conditions
- Acute Myeloid Leukemia in Remission, Primary Myelofibrosis, Primary Myelofibrosis, Prefibrotic Stage, Secondary Acute Myeloid Leukemia
- Trial name
- NCT02528877
- Testing
- Allogeneic Bone Marrow Transplantation, Allogeneic Hematopoietic Stem Cell Transplantation, Fludarabine Phosphate
- Where
- United States
- Sponsor
- City of Hope Medical Center
Spinal Stenosis Lumbar, Neuropathic Pain
Neuropathic Pain Severity and Its Association With Radiological Findings in Lumbar Spinal Stenosis
This cross-sectional observational study aims to evaluate neuropathic pain severity in patients with lumbar spinal stenosis (LSS) and to investigate its association with radiological findings.
- Trial name
- NCT07855445
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Marmara University
Cervical Cancer
High Dose Intensity Modulated Radiation Therapy in the Cervical Cancer With Metastatic Lymphadenopathies.
This phase II study of high dose intensity modulated radiation therapy in the cervical cancer with metastatic lymphadenopathies at initial diagnosis
- Trial name
- NCT01730651
- Testing
- Tomotherapy
- Where
- 2 sites in South Korea
- Volunteers
- 55 people
- Sponsor
- National Cancer Center, Korea
Chronic Pain, Musculoskeletal Pain
Education on BDNF on Pain Levels
The promotion of neuroplasticity in conjunction with strategies for restructuring maladaptive cognitions that largely cause the activation of neural networks that contribute to the perpetuation of pain is therefore a fundamental…
- Trial name
- NCT05623579
- Testing
- Pain Neuroscience Education, Exercise
- Where
- 2 sites in Spain
- Volunteers
- 66 people
- Sponsor
- Universidad Autonoma de Madrid
Anxiety, Pain
The Effect of Virtual Reality Application on Pain Severity, Anxiety Level and Patient Satisfaction
In this study; It is aimed to examine the Effect of Virtual Reality Based Relaxation Program on Pain Severity, Anxiety Level and Patient Satisfaction in Patients Who Will Be Applied Angiography.
- Trial name
- NCT05459246
- Testing
- Virtual reality glasses
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Sabahattin Zaim University
Type 2 Diabetes, Lifestyle-related Condition
High Intensity Interval Training and Insulin Sensitivity in Type 2 Diabetes
A recognized driver for cardiovascular complications of type 2 diabetes mellitus (T2DM) is impaired plasma glucose homeostasis as consequence of skeletal muscle insulin resistance.
- Conditions
- Type 2 Diabetes, Lifestyle-related Condition, Insulin Sensitivity/Resistance
- Trial name
- T2D-HIIT (NCT06688461)
- Testing
- Experimental group: Exercise training
- Where
- Chile
- Volunteers
- 36 people
- Sponsor
- Finis Terrae University
Foot, Sleep
Effect of Footbath on Pain Severity and Sleep Quality
The goal of this clinical trial is to examine the effect of hot water foot bath on the patients' pain severity and sleep quality levels on the night of the lumbar degenerative disc surgery.
- Conditions
- Foot, Sleep, Pain
- Trial name
- NCT05658783
- Testing
- Hot water foot bath
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Trakya University
Motivational Interviewing, Schizophrenia Spectrum Disorder
Effects of Adherence Therapy on Medication Adherence in Patients With Schizophrenia Spectrum Disorder
This study will explore the effect of Adherence Therapy(AT) on medication adherence in patients with schizophrenia spectrum disorder.
- Conditions
- Motivational Interviewing, Schizophrenia Spectrum Disorder, Medication Adherence
- Trial name
- NCT04022577
- Testing
- Adherence Therapy, control group
- Where
- Taiwan
- Volunteers
- 120 people
- Sponsor
- National Yang Ming Chiao Tung University
Graves Disease
HIFU vs RAI in the Relapsed Graves' Disease
Graves' disease (GD) is an autoimmune thyroid disorder caused by stimulating auto-antibodies to the thyrotrophin (TSH) receptor on thyroid follicular cells.
- Trial name
- NCT03013257
- Testing
- Echopulse
- Where
- Hong Kong
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Pancreatic Cancer
Intensity-Modulated Radiation Therapy and Gemcitabine in Treating Patients With Locally Advanced Pancreatic Cancer
RATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.
- Trial name
- NCT00878657
- Testing
- gemcitabine hydrochloride, intensity-modulated radiation therapy
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Rutgers, The State University of New Jersey
Cancer, Solid Tumor
Home-Based Symptom Monitoring: Its Impact on Cancer Care Team Behaviors and Patient Outcomes
The primary research objective of this protocol is to evaluate the impact of integrating a home-based symptom monitoring system in the day-to-day care of cancer patients in community settings on the frequency of supportive…
- Conditions
- Cancer, Solid Tumor, Hematologic Malignancy
- Trial name
- NCT00300001
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- Community Cancer Care
COPD
Serum Surfactant Protein-D as Predictor of Disease Severity in Hospitalized COPD Patients
evaluation of the serum levels of surfactant protein-D (SP-D), C-reactive protein (CRP), fibrinogen, and peripheral blood neutrophilic and eosinophilic counts in patients with COPD correlation of these biomarkers with clinical…
- Trial name
- NCT07154953
- Testing
- Serum Surfactant Protein-D
- Volunteers
- 75 people
- Sponsor
- Assiut University