Clinical trials: Disease Spread
Allergic Skin Reaction
Evaluation of the Allergenicity of AMPHADASE INJECTION (Hyaluronidase Injection USP)
This study is designed to evaluate the allergenicity of Amphadase® in healthy volunteers using an intradermal skin test.
- Trial name
- H001-A2 (NCT01689363)
- Testing
- Hyaluronidase, Histamine, Saline
- Where
- 5 sites in United States
- Volunteers
- 253 people, healthy volunteers welcome
- Sponsor
- Amphastar Pharmaceuticals, Inc.
Nurse's Role, Pain Management
Effect of Virtual Reality on Pain and Anxiety During Pap Smear Testing
This randomized controlled pretest-posttest experimental study aims to evaluate the effect of virtual reality (VR) on pain and anxiety levels experienced during Pap smear sampling.
- Conditions
- Nurse's Role, Pain Management, Cervical Cancer Screening, Anxiety
- Trial name
- NCT07462039
- Testing
- Virtual Reality
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Germline Mutations
Early Diagnosis of High-grade Serous Epithelial Ovarian Cancer Through the Analysis of DNA Derived From Pap Test Smear.
Ovarian cancer is the leading cause of death among gynecological malignancies. No screening test is available for this tumor. Serous Tubal Intraepithelial Carcinoma (STIC) is the precursor lesion of the high grade serous ovarian…
- Trial name
- EVATEST (NCT07556562)
- Testing
- RRSO (risk-reducing salpingo- oophorectomy) or RRS (risk-reducing salpingectomy)
- Where
- Italy
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Health Behavior, COVID-19
Nudges to Improve Health Behaviors That Limit COVID-19 Spread
This investigation is a randomized intervention trial that evaluates behavioral nudges (BN) to increase hand washing behavior and subsequently reduce COVID-19 spreading to a targeted high-risk patient population based in…
- Trial name
- NCT04379375
- Testing
- Nudge
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Adenoma Colon, Serrated Polyp
Cold EMR Vs Standard EMR for the Treatment of Large Nonpedunculated Homogeneous Colorectal Lesions
This study compares the effectiveness in complete resection (absence of recurrence at 6 months) the two different techniques for performing endoscopic mucosal resection (EMR) of nonpedunculated homogeneous colorectal lesions >20mm
- Conditions
- Adenoma Colon, Serrated Polyp, Serrated Adenoma, Colorectal Neoplasms
- Trial name
- NCT04418843
- Testing
- Standard Endoscopic Mucosal Resection, Cold Snare Endoscopic Mucosal Resection
- Where
- Spain
- Volunteers
- 229 people, healthy volunteers welcome
- Sponsor
- Oscar Nogales
Covid-19, Virus Disease
Spread and Course of COVID-19 Infections
The overall goal is to study the immune response to SARS-CoV-2 infection over the period of one year in the blood of a representative cohort of ETH students/employees.
- Trial name
- CoV-ETH (NCT04377724)
- Where
- Switzerland
- Volunteers
- 2,910 people, healthy volunteers welcome
- Sponsor
- Goldhahn Jörg
SARS-CoV-2 Infection
Intervention to Prevent Household and Community Spread of COVID-19 Among Latinos
This study will examine the effectiveness of a 6-week behavioral intervention for patients who are recently diagnosed with COVID-19. Patients and their households will be randomized to one of two groups (Standard of Care vs.
- Trial name
- NCT05697068
- Testing
- COVID Prevention Program (CPP)
- Where
- United States
- Volunteers
- 256 people, healthy volunteers welcome
- Sponsor
- San Diego State University
Respiratory Insufficiency
Evaluation of Leak-free Bronchoscope Adapter
Patients who develop respiratory failure require the assistance of mechanical ventilation while recovering from their respiratory injury.
- Trial name
- NCT05288218
- Testing
- Leak-free Bronchoscope Adapter, Standard Bronchoscope Adapter
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Cervical Cancer
Increasing Participation in Cervical Cancer Screening and Risk for Beliefs/Attitudes Among Women at Risk
In order to evaluate the effectiveness of nursing interventions aimed at the early detection of cervical cancer, health belief and participation in the screening of women aged 40-55 at risk for the purpose of cervical cancer…
- Trial name
- NCT03076879
- Testing
- Promoting participation in cervical cancer screening
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Papillomavirus Infections
Gardasil Vaccination as Therapy in Low Grade Cervical Abnormalities
This project will compare the rate of regression of minimally abnormal Pap smears to normal in women who receive Gardasil to a historical control group.
- Trial name
- NCT00501189
- Testing
- human papillomavirus vaccine L1, type 6,11,16,18
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Eisenhower Army Medical Center
COVID-19
Direct Income SupporT and Advice Negating Spread of Epidemic COVID-19: a Randomized Controlled Trial
This is a clinical trial of a cash transfer on symptoms consistent with COVID-19 and adherence to physical distancing guidance.
- Trial name
- DISTANSE COVID (NCT04359264)
- Testing
- Cash transfer
- Where
- 2 sites in Canada
- Volunteers
- 392 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
HPV Infection, Cervical/Anal Dysplasia
HPV in Adolescents
This study will assess the prevalence of HPV infection in perinatally HIV-infected adolescents, intraepithelial neoplasia, and E6E7 biomarker at cervical and anal sites.
- Trial name
- NCT01788852
- Where
- 3 sites in Thailand
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- The HIV Netherlands Australia Thailand Research Collaboration
Cervical Cancer
Cervical Cancer Detection Using Optical Spectroscopy
The objective of the work described in this protocol is to determine the optical signatures of cervical dysplasia using optical technologies.
- Trial name
- NCT00900575
- Testing
- Optical Spectroscopy Bench-Top System, Portable Optical Spectrometer, Transvaginal colposcope
- Where
- United States
- Volunteers
- 350 people, healthy volunteers welcome
- Sponsor
- Duke University
Parkinson's Disease (PD), GBA1 Parkinson Disease
Understanding Alpha-Synuclein Spread in Parkinson's Disease Through Blood Biomarkers and Neuroimaging
The project aims to investigate how abnormal accumulation of alpha synuclein and its interaction with tau influence brain function across the Parkinson's disease (PD) spectrum, with particular focus on individuals carrying GBA1…
- Conditions
- Parkinson's Disease (PD), GBA1 Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
- Trial name
- SYNchronPD (NCT07474779)
- Testing
- brain imaging, blood draw, Skin biopsy
- Where
- 2 sites in Italy
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Pavia
Malaria
Malaria Prevalence Around Maferinyah, Guinea
Background: Many women in Sub-Saharan Africa get malaria while they are pregnant. Plasmodium falciparum is a parasite that can cause malaria. Placental malaria (PM) caused by P.
- Trial name
- NCT04105855
- Where
- Guinea
- Volunteers
- 3,392 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Carcinoma in Situ of Uterine Cervix
Follow-up of Abnormal and Inadequate Smear-test Results
Denmark has a higher incidence of cervical cancer than other Nordic countries, although all Danish women (aged 23-65) are screened regularly to identify possible cervical dysplasia or asymptomatic invasive cancer.
- Trial name
- NCT02002468
- Testing
- Test result sent by letter, Test result conveyed by general practitioners
- Where
- Denmark
- Volunteers
- 125,000 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Droplet Spread, Covid19
COVID-19 Aerosol in EGD Using a Droplet Reduction Mouthpiece
Measurement of aerosolisation during esophagogastroduodenoscopy (EGD) to compare two types of mouthpieces, conventional versus a new and commercially available one 'the droplet reduction mouthpiece B1'.
- Trial name
- NCT04864015
- Testing
- Mouthpiece B1(Mouthpiece MPC-ST GMDN:62534 Generic name: Endoscopic bite block, basic, reusable
- Where
- Belgium
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Cervical Neoplasia
Measurement of Digital Colposcopy for Fluorescence Spectroscopy of TNC Using a Second Device
The overall objective of this study is to identify potential improvements for a noninvasive method of diagnosing dysplasia and neoplasia in the cervix using Multi-spectral Digital Colposcopy (MDC), a device that uses fluorescence…
- Trial name
- NCT00503919
- Testing
- Multi-spectral Digital Colposcopy (MDC)
- Volunteers
- healthy volunteers welcome
- Sponsor
- M.D. Anderson Cancer Center
Cervix Cancer
Prevalence of Abnormal Pap Smear
This study aims to evaluate prevalence of abnormal Pap smear among sexually active women of reproductive age attending sohag university hospital outpatient clinic.
- Trial name
- NCT06641531
- Testing
- Screening pap smear test
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sohag University
Being a Woman Aged 18-65
Evaluation of the Effectiveness of the Video Prepared to Raise Cervical Cancer Awareness in Women Between the Ages of 18 and 65 Via Social Media.
This research, a quasi-experimental study based on the comparison of the pre-test and post-test results of individuals in a single group is conducted to raise awareness about cervical cancer in women aged 18-65 years.
- Trial name
- NCT05385172
- Testing
- No any intervation.
- Where
- Turkey (Türkiye)
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa