Clinical trials: Diseases, Metabolic
Type 2 Diabetes
24 Hour Plasma Glucose Profiles Comparing Lispro Mix 75/25 vs. Glargine
The purpose of this study is to determine if twice-daily Lispro low mixture (75/25) will result in lower post prandial blood glucose readings versus once-daily glargine plus oral diabetic medications.
- Trial name
- NCT00551538
- Testing
- Lispro mix 75/25, Glargine
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Eli Lilly and Company
Inflammatory Bowel Diseases, Colitis, Ulcerative
Protein and Magnesium in Ulcerative Colitis
The aim of the study is to improve the quality of nutritional therapy for patients admitted with Acute Severe Ulcerative Colitis (ASUC) treated with high-dose steroids.
- Conditions
- Inflammatory Bowel Diseases, Colitis, Ulcerative, Magnesium Deficiency, Nutritional Deficiency
- Trial name
- PAMUC (NCT05271838)
- Testing
- Magnesium acetate mixture (30 mmol/ml), High-protein diet (2 g/kg/day)
- Where
- Denmark
- Volunteers
- 36 people
- Sponsor
- University of Aarhus
Hypogonadism, Paraplegia
Efficacy of Nebido on Bone Mineral Density (BMD) in Hypogonadal Paraplegic Patients With Confirmed Osteoporosis
Both conditions hypogonadism and immobilisation (paraplegia) may contribute or lead to decreased bone mineral density resp osteoporosis.
- Conditions
- Hypogonadism, Paraplegia, Bone Density, Osteoporosis
- Trial name
- NCT00838838
- Testing
- Testosterone Undeconate (Nebido-R, BAY86-5037)
- Where
- Germany
- Volunteers
- 26 people
- Sponsor
- Bayer
Childhood Obesity
Kids' Choice Restaurant Program
This study will introduce healthy child menu items into 8 independent full service restaurants in San Diego County. The restaurants will be assigned either to receive new, healthy kids' menu items or to receive the new menu items…
- Trial name
- KCRP (NCT02511938)
- Testing
- Menu Only, Menu Plus intervention
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- San Diego State University
Obesity, Cardiovascular Disease
The Effect of Oral Alpha-Cyclodextrin on Fecal Fat Excretion
Saturated fat leading to elevated low density lipoprotein (LDL) cholesterol is considered a cardiovascular risk factor. The properties associated with α- cyclodextrin, allow it to selectively reduce saturated fat and calories…
- Trial name
- FAT ABSORBER (NCT01910558)
- Testing
- Alpha-cyclodextrin and digestible starch, Alpha-cyclodextrin, Digestible starch
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Pennington Biomedical Research Center
Hypercholesterolemia
LDL-Cholesterol Lowering Effect of KB2115 as Add on to Ezetimibe
Eprotirome (KB2115) is a liver selective thyroid hormone that can induce hyperthyroidism in the liver, while an euthyroid state is preserved in the extrahepatic tissue.
- Trial name
- NCT00677248
- Testing
- Eprotirome and ezetimibe
- Where
- Sweden
- Volunteers
- 120 people
- Sponsor
- Karo Bio AB
Asthma
Effect of Inhaled Steroids on Glucose Regulation in Asthma Patients
Inhaled steroid has been the cornerstone in the treatment of asthma, which carries a huge patient population worldwide including Hong Kong. In general, the safety of long-term use of inhaled steroid has been well documented.
- Trial name
- NCT00959348
- Where
- 4 sites in Hong Kong
- Volunteers
- 1,394 people
- Sponsor
- The University of Hong Kong
Diabetes Mellitus
Diabetes and Social Issues: Evaluation of a Diabetes Education Module
This study is a multi-center, randomized prospective trial with a 6-month follow up. A newly developed treatment and education module will be tested compared to a waiting-list control group.
- Trial name
- PRIMO_Social (NCT02076555)
- Testing
- Education - Diabetes and Social Issues
- Where
- 4 sites in Germany
- Volunteers
- 256 people
- Sponsor
- Forschungsinstitut der Diabetes Akademie Mergentheim
Obesity, Bariatric Surgery
Protein Need and Interest of " Quick Proteins " to the Obese Subject Operated by Bariatric Surgery (BIBOP)
The main objective of the study is to evaluate the protein requirement associated with postoperative weight loss caused by by-pass (shunt which leads to a certain degree of malabsorption) or sleeve gastrectomy (more technically…
- Trial name
- BIBOP (NCT01249326)
- Testing
- bariatric surgery
- Where
- France
- Volunteers
- 25 people
- Sponsor
- University Hospital, Clermont-Ferrand
MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Normobaric Hypoxia
Effects of Normobaric Hypoxic Training in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)
Altitude training has been suggested to be of potential support to improve some chronic clinical conditions, especially metabolic conditions.
- Trial name
- HYPOMASLD (NCT07073326)
- Testing
- HYPOTRAIN, NORMOTRAIN
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- University of Trieste
Diabetes
Comparison Evaluation of Blood Glucose Meter Systems
The purpose of this study was to evaluate the performance of one investigational Bayer Blood Glucose meter (with investigational Bayer test strips) and four Blood Glucose Monitoring Systems from other companies.
- Trial name
- NCT01548885
- Testing
- CONTOUR® NEXT EZ BGMS, FreeStyle Freedom Lite® BGMS, ACCU-CHEK® Aviva BGMS
- Where
- United States
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Ascensia Diabetes Care
Hyperphosphatemia, Kidney Disease
Chewed vs. Crushed Lanthanum Carbonate in Hemodialysis Patients
Patients with end-stage renal disease (ESRD) commonly develop hyperphosphatemia due to the loss of excretory function of the kidney.
- Trial name
- NCT00660530
- Testing
- Lanthanum Carbonate Chewable Product, Lanthanum carbonate crushed powder
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Illinois Chicago
Overweight, Obesity
Liquid Meal Replacements in Conjunction With Lifestyle Intervention in Overweight Adolescents
In this 3-month pilot study, we will introduce to 40 adolescents "at risk for overweight" (i.e., a BMI/age >85th percentile) a structured meal plan consisting of meal replacements, fruits, vegetables, whole grains, lean protein…
- Trial name
- NCT00207519
- Testing
- weekly behavioral modification group, liquid meal replacements
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Boston Medical Center
Hypercholesterolemia
Vascular and Metabolic Effects of Rosuvastatin
The investigators hypothesize that rosuvastatin does-dependently worsens insulin sensitivity.
- Trial name
- NCT01660919
- Testing
- rosuvastatin
- Where
- South Korea
- Volunteers
- 160 people
- Sponsor
- Gachon University Gil Medical Center
DNA Virus Infection, Herpesviridae Infections
Prophylaxis With Ganciclovir Improves Graft Survival in Renal Allograft Recipients
Study Phase: IV Study Type: Open-label, multicenter, randomised clinical trial with two arms stratified for an intensified immunosuppressive regimen in patients at high risk for acute rejection.
- Conditions
- DNA Virus Infection, Herpesviridae Infections, Cytomegalovirus Infection
- Trial name
- NCT00373165
- Testing
- Ganciclovir
- Volunteers
- 150 people
- Sponsor
- Lower Saxony Center for Nephrology
Iron-deficiency Anemia, Iron-deficiency
Bloodsafe Ghana- Iron and Nutritional Counseling Strategy Pilot Study
This pilot study has 2 components: 1) a cross-sectional assessment designed to estimate the prevalence of anaemia leading to donor deferral, the prevalence of iron deficiency (ID) and iron deficiency anaemia (IDA) among…
- Trial name
- BLIS (NCT04949165)
- Testing
- Iron Supplementation
- Where
- Ghana
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Obesity
A Safety and Efficacy Study of VI-0521 to Evaluate the Long Term Treatment of Obesity in Adults With Obesity-Related Co-Morbid Conditions. An Extension Study of Protocol OB-303 (NCT00553787)
The purpose of this study is to evaluate the long-term safety and efficacy of VI-0521 compared to placebo for the treatment of overweight and obesity in adults who have completed study OB-303 (NCT00553787) at selected study…
- Trial name
- NCT00796367
- Testing
- VI-0521
- Volunteers
- 676 people
- Sponsor
- VIVUS LLC
Diabetes Mellitus, Type 1
Patient Empowerment Through Predictive Personalised Decision Support (PEPPER)
Patient Empowerment through Predictive PERsonalised decision support (PEPPER) is an European Union (EU) funded research project to develop a personalised clinical decision support system for Type 1 Diabetes Mellitus (T1DM)…
- Trial name
- PEPPER (NCT03186300)
- Testing
- PEPPER system
- Where
- Spain
- Volunteers
- 8 people
- Sponsor
- Institut d'Investigació Biomèdica de Girona Dr. Josep Trueta
Obesity and Type 2 Diabetes
Circuit Training and Motivational Interviewing to Reduce Type 2 Diabetes in Youth
The overall goal of this project is to examine the physiological and metabolic effects of a 16-week circuit-training (strength training + aerobic activities) program, with and without a behavioral component utilizing motivational…
- Trial name
- NCT00693511
- Testing
- Circuit Training, Circuit training + motivational interviewing
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Adiposity
Safety and Efficacy of Deoxycholic Acid Injection for Reduction of Upper Inner Thigh Fat
This is a phase I, open-label clinical trial evaluating the safety and efficacy of deoxycholic acid injection for reduction of upper inner thigh fat.
- Trial name
- NCT04054011
- Testing
- Deoxycholic Acid
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
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