Clinical trials: Diseases, Metabolic
Type 1 Diabetes, Pregnancy
Pilot Study of Between Visit Interaction to Improve Glycemic Control in Pregnancy With Pre-existing Diabetes
Hypothesis: Increased contact with the diabetes care team throughout pregnancy will lead to improved glucose control during pregnancy.
- Trial name
- NCT02315274
- Testing
- Frequent remote contact between clinic visits.
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Mayo Clinic
Stem Cells, Type 1 Diabetes
Insulin Producing Stem Cell Transplantation Clinical Trial in Type 1 Diabetes
Type 1 Diabetes is a chronic autoimmune disease. It results from autoimmune destruction of pancreatic Beta cells leading to absolute insulin insufficiency.
- Trial name
- NCT06951074
- Testing
- Insulin producing stem cells infusion
- Where
- Egypt
- Volunteers
- 20 people
- Sponsor
- Ain Shams University
Osteoporosis, Postmenopausal
Motor Control Exercise in Osteoporotic Women
The objective of this study was to explore the effectiveness of Motor Control Exercise on pain, postural alignment and spinal curvatures in women with osteoporotic vertebral fractures.
- Trial name
- NCT01172574
- Testing
- Motor control exercise
- Where
- Greece
- Volunteers
- 20 people
- Sponsor
- National and Kapodistrian University of Athens
Polycystic Ovary Syndrome
AMH, Glucose Intolerance and Metabolic Syndrome in PCOS
Association between serum anti-Mullerian hormone (AMH) level and prevalence of glucose intolerance and metabolic syndrome in women with polycystic ovary syndrome (PCOS)
- Trial name
- NCT02676518
- Testing
- serum
- Where
- Thailand
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Diabetes, Diabetes Mellitus, Type 1
Investigation of Pharmacodynamic Characteristics of Explorative Formulation of Insulin Degludec in Male Subjects With Type 1 Diabetes
This trial is conducted in Europe. The aim of this trial is to investigate the pharmacodynamic (the effect of the investigated drug on the body) of insulin degludec (insulin 454), an explorative formulation, not similar to the…
- Trial name
- NCT01865318
- Testing
- insulin degludec
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Novo Nordisk A/S
Type 2 Diabetes Mellitus
Switch From U-100 Insulin Analog to U-500 Regular Insulin in Pumps for Type 2 Diabetes
The aim of the study was to perform a 3-year retrospective analysis from a cohort of patients with type 2 diabetes that were treated by a pump device and were uncontrolled despite high U-100 insulin requirements.
- Trial name
- NCT04371497
- Volunteers
- 65 people
- Sponsor
- University Hospital, Caen
Glucose, Diabetes
Cmate Blood Glucose Analyzer: Clinical Comparison Study of Fasting Blood Glucose Levels in the Morning
As of February 2024, there are 529 million people worldwide living with diabetes. The number of diabetes patients continues to rise annually, and there is also a trend toward younger patients.
- Trial name
- NCT07088497
- Testing
- dietary control
- Where
- Taiwan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Revlis Biotech Company Limited
Wound Complication
PROphylactic Wound VACuum Therapy to Decrease Rates of Cesarean Section in the Obese Population
This study will assess whether a negative pressure wound vacuum therapy (NPWT) on closed incisions decreases the risk of wound complications among obese patients after cesarean section All patients having a cesarean section in…
- Trial name
- PROVAC (NCT02128997)
- Testing
- Closed incision wound vacuum (Prevena)
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Morbid Obesity
Stool Analysis After Sleeve Gastrectomy vs Gastric Bypass
The goal of this observational study is to learn whether routine stool tests can detect changes in gut function 6 months after two common types of weight loss surgery: sleeve gastrectomy and gastric bypass (including mini gastric…
- Trial name
- NCT07461610
- Testing
- Laparoscopic Sleeve Gastrectomy, Mini Gastric Bypass, Roux-en-Y Gastric Bypass
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Cairo University
Leukemia, Lymphoma
Nutritional Assessment Intervention to Improve Cancer-Related Fatigue
Primary Objective: 1. To use the results from this pilot study to estimate the effect size of the nutritional intervention on fatigue and caloric intake. Secondary Objectives: 1.
- Conditions
- Leukemia, Lymphoma, Fatigue
- Trial name
- NCT00507260
- Testing
- Food Record, Nutritional Consults
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- M.D. Anderson Cancer Center
X-linked Hypophosphatemia
Anti-FGF23 (Burosumab) in Adult Patients With XLH
X-linked hypophosphatemia (XLH) rare genetic disorder due by inactivating mutations in the PHEX gene leading to increased levels in FGF-23.
- Trial name
- BurGER (NCT04695860)
- Testing
- Burosumab
- Where
- Germany
- Volunteers
- 36 people
- Sponsor
- Wuerzburg University Hospital
Periodontitis, Diabetes Mellitus
Efficacy of Hydrogen Peroxide Gel on Periodontitis With Diabetes
Periodontitis is a chronic infectious disease characterized by loss of tooth supporting periodontal structures and alveolar bone. In the U.S. and worldwide, periodontitis is the major cause of tooth loss in adults.
- Trial name
- Peroxide gel (NCT05669560)
- Testing
- PerioProtect ™= plastic tray +1.7% hydrogen peroxide
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Oklahoma
Type 1 Diabetes
Evaluation of Glycemic Control and Quality of Life in Adults With Type 1 Diabetes During Continuous Glucose Monitoring When Switching to Insulin Glargine 300 U/mL
Retrospective multicenter study analyzing data gathered during the FUTURE study (S59342) to assess the effect of using Insulin Glargine 300 U/mL (Gla-300) on measures of diabetes control and quality of life.
- Trial name
- FUTURE-GLARE (NCT05109520)
- Testing
- Insulin Glargine 300 UNT/ML [Toujeo]
- Where
- 3 sites in Belgium
- Volunteers
- 867 people
- Sponsor
- prof dr Pieter Gillard
Contraception, Obesity
The Effect of Body Mass Index on Etonogestrel Hormone Levels in Women Using the Single-rod Contraceptive Implant
Two-thirds of young women in the United States are overweight or obese. This excess weight may affect how their body metabolizes drugs such as different birth control methods.
- Trial name
- Eto BMI (NCT01855620)
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Columbia University
Type 2 Diabetes, Psoriasis
Effect of GLP-1 Analogs on Psoriasis in Type 2 Diabetic Patients
The aim of the study is to evaluate after 4 to 6 months the effects of a GLP-1 analog treatment on psoriatic skin lesions in patients with type 2 diabetes.
- Trial name
- NCT01687582
- Testing
- GLP-1 analog
- Where
- Belgium
- Volunteers
- 10 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Metabolic Syndrome
Study the Role of Genetic Variation in the Determining Lipid Profile Response to Dietary Change
The purpose of this study is to determine whether plasma lipoproteins and lipid responsiveness to a dietary modification is influenced by CETP gene polymorphism.
- Trial name
- NCT00673023
- Testing
- Dietary experiments
- Volunteers
- 102 people
- Sponsor
- Tabriz University
Cardiovascular Diseases, Hypertension
Uppsala Self-Screening of Cardiovascular Health
U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can…
- Conditions
- Cardiovascular Diseases, Hypertension, Dyslipidemias, Diabetes Mellitus
- Trial name
- U-SCREEN (NCT07614659)
- Testing
- Home-based multimodal cardiovascular screening
- Where
- Sweden
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Johan Sundström
Type 1 Diabetes
Evaluation of Functional Insulin Therapy in Type 1 Diabetic Patients
Functional Insulin Therapy (FIT) is an heath care method proposed to type 1 diabetic patients which focuses on patient autonomy, carbs counting and insulin dose adaptation.
- Trial name
- IFOPI (NCT01512680)
- Testing
- Education to Functional Insulin Therapy
- Where
- France
- Volunteers
- 52 people
- Sponsor
- University Hospital, Montpellier
Metabolic Syndrome, Non-alcoholic Fatty Liver Disease
Effect of Dietary Macronutrient Composition
The purpose of this study is to understand why Hispanics who are overweight have a higher incidence of fatty liver disease.
- Conditions
- Metabolic Syndrome, Non-alcoholic Fatty Liver Disease, Obesity
- Trial name
- NCT01371396
- Testing
- Low-fat diet, Low-carbohydrate diet
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- University of Texas Southwestern Medical Center
Obesity &Amp; Overweight
Can Gut Bacteria Predict Who Benefits Most From Exercise? A Gut Supplement to Help Exercise Non-Responders
Overview: You are invited to participate in a research study. You can join if you are a woman, 18-40 years old, have a BMI >25, and a regular menstrual cycle (every 24 to 38 days, per the Cleveland Clinic).
- Trial name
- NCT07180446
- Testing
- Cardiovascular Exercise, Butyrate
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Texas Christian University
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