Clinical trials: Disorder
Bipolar Disorder
Bipolar Disorder in Late Life
The purpose of this study is to look at certain structural changes in the brain in people with bipolar disorder or those with a history of Bipolar disorder.
- Trial name
- BPD (NCT00787930)
- Testing
- Valproic Acid
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Duke University
Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension
Right Atrial Fibrosis in Pulmonary Hypertension
The study aim to assess right atrial (RA) remodeling, in terms of RA fibrosis, in pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension patients.
- Conditions
- Pulmonary Hypertension, Chronic Thromboembolic Pulmonary Hypertension, Pulmonary Arterial Hypertension
- Trial name
- RAFE-PH (NCT04663230)
- Testing
- cardiac magnetic resonance imaging
- Where
- 2 sites in Germany
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Giessen
Opioid-Related Disorders, Pain, Acute
A Comparison of Plasma Concentrations of Hydrocodone and Acetaminophen After Administration of Different Amounts of Tablets of a New and a Marketed Tablet Formulation in Healthy Adults
This clinical trial is being conducted to compare concentrations of hydrocodone and acetaminophen in the blood after administration of different amounts of tablets of a new and a marketed tablet formulation in healthy adults.
- Conditions
- Opioid-Related Disorders, Pain, Acute, Pain, Postoperative
- Trial name
- NCT03137030
- Testing
- GRT7014 - Abuse Deterrend Tablet, Norco 5Mg-325Mg Tablet
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Grünenthal GmbH
Uterine Fibroid, Pregnancy Complications
Pregnancy Outcomes Following Myomectomy
The most prevalent genital pathology, uterine fibroids have a detrimental impact on the health of women. Fibroid symptoms are typically more impactful on females and frequently require uterine excision.
- Conditions
- Uterine Fibroid, Pregnancy Complications, Reproductive Issues, Reproductive Sterility
- Trial name
- NCT06474065
- Testing
- Myomectomy
- Where
- Italy
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Centro di Ricerca Clinica Salentino
Anemia, Nutritional Deficiency
Anemia in Older Adults
A cross-sectional study with 829 older Mexican adults were recruited from July to September 2015, from four localities in the southern region of México.
- Conditions
- Anemia, Nutritional Deficiency, Inflammation
- Trial name
- NCT04820465
- Testing
- Non available due to cross-sectional study design
- Volunteers
- 829 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Salud Publica, Mexico
Acute Lymphoid Leukemia, Acute Myeloid Leukemia in Children
Study of the Medullary Microenvironment in Acute Childhood Leukemia
Acute leukemia (AL) is the most common cancer in children. Despite the optimization of chemotherapy treatments and the development of supportive care, a certain number of LAs relapse and/or progress to death of the child.
- Trial name
- MILA (NCT05792007)
- Testing
- Biological sampling in patients, Biological sampling in control patients
- Where
- 3 sites in France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Bipolar 1 Disorder, Control Subjects
Socio-cognitive and Biological Responses to Maltreatment
The study will investigate how a history of emotional childhood maltreatment (CM) is associated with different aspects of psychological (social behaviour, empathy) and biological (brain function and structure, inflammation)…
- Trial name
- NCT07101107
- Where
- Austria
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Osteoporosis
Pharmacokinetics and Tolerability of Minodronic Acid and Food and Age Effects on the Pharmacokinetics
The primary objective of the the study was to evaluate the pharmacokinetic properties of minodronic acid tablets following single and multiple oral administration in healthy Chinese subjects.
- Trial name
- NCT02295436
- Testing
- minodronic acid
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction
COVID-19 Vaccination Detoxification in LDL-C
The study hypothesizes that SARS-CoV-2 vaccination poisoning hibernates in human host in Low Density Lipoprotein Cholesterol (LDL-C). The clinical trial is a follow-up from the intervention trial with NCT number NCT05711810.
- Conditions
- COVID-19 Stress Syndrome, COVID-19 Vaccine Adverse Reaction, COVID-19-Associated Thromboembolism, COVID-19 Post-Intensive Care Syndrome
- Trial name
- NCT05839236
- Testing
- Atorvastatin Calcium Tablets
- Where
- China
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Yang I. Pachankis
Otitis Media
Genetics of Middle Ear Disease
The goal of this study is to identify the genes that contribute to susceptibility to recurrent/persistent middle ear disease. Five hundred families with at least 2 children who have undergone tympanostomy tube insertion will be…
- Trial name
- NCT00422136
- Where
- United States
- Volunteers
- 2,121 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Obesity
Effect and Safety of TCM-FMD in Phlegm-Dampness Type Overweight/Obesity Patients(EASTAR)
The primary aim of this study is to is to determine if a diet (TCM-FMD) which combine fasting-mimicking diet (FMD) with "dispelling dampness" meal replacement (a meal replacement made up of traditional Chinese medicine) is the…
- Trial name
- NCT04029571
- Testing
- TCM-FMD, FMD
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Guangdong Provincial Hospital of Traditional Chinese Medicine
Renal Impairment, Diabetes
Pharmacokinetics of Vildagliptin in Mild, Moderate and Severe Renal Impaired Patients
This study assess the pharmacokinetics of vildagliptin in mild, moderate and severe renal impaired patients
- Trial name
- NCT00818571
- Testing
- Vildagliptin
- Where
- Russia
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
Gout
Food Effect Study of Febuxostat XR in Healthy Participants
The purpose of this study is to assess the effect of food on the bioavailability of febuxostat after a single oral dose of 80 mg febuxostat XR and to evaluate the pharmacokinetics (PK) of febuxostat after single oral doses of 40…
- Trial name
- NCT02374164
- Testing
- Febuxostat XR
- Where
- United States
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Takeda
Healthy Volunteers, Hypercholesterolaemia
A Research Study Investigating How NNC0385-0434 is Tolerated in People With or Without High Cholesterol Levels
In this study, there are two study medicines: NNC0385-0434 (the new medicine being tested) and placebo (a 'dummy' medicine). Participants will only get one of these medicines - which one is decided by chance.
- Trial name
- NCT04058834
- Testing
- NNC0385-0434
- Where
- United Kingdom
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Chronic Obstructive Pulmonary
Involvement of Plasmatic Factors in the Peripheral Muscle Dysfunction of COPD Patients - In Vitro Study
Chronic Obstructive Pulmonary Patients is a defined by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or…
- Trial name
- NCT03197909
- Testing
- Determination of pro-inflammatory plasma factors
- Where
- France
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Depression in Adults, Anxiety Disorder Generalized
ACT for Individuals With MNCD and Their Care Partners
This project aims to implement and evaluate a dyadic intervention (i.e., acceptance commitment therapy) for persons with AD/ADRD and their care partners.
- Conditions
- Depression in Adults, Anxiety Disorder Generalized, Grief
- Trial name
- ACT (NCT07239609)
- Testing
- Acceptance Commitment Therapy
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Texas Tech University
Postoperative Cognitive Dysfunction
The Influence of Postoperative Analgesia on Systemic Inflammatory Response and POCD After Femoral Fractures Surgery
The purpose of this study is to determine whether epidural levobupivacaine applied for the purpose of post-operative analgesia compared to systemic analgesia with morphine leads to better pain control, stronger suppression of the…
- Trial name
- NCT02848599
- Testing
- morphine, levobupivacaine
- Where
- Croatia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Osijek University Hospital
Alzheimer Disease, Mild Cognitive Impairment
Individual Closed-Loop Neuromodulation Therapy for Alzheimer's Disease
The project is a placebo-controlled study that aims to use closed-loop transcranial alternating current stimulation (tACS) to study patients with symptoms of mild cognitive impairment which is likely due to Alzheimer's disease or…
- Trial name
- NCT05904132
- Testing
- tACS device
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Colorectal Cancer
Comparing Interventions to Increase Colorectal Cancer Screening
The purpose of this study is to test different approaches to help people understand the purpose of colorectal cancer (CRC) screening, two screening test options available, and the barriers to screening so they can make informed…
- Trial name
- NCT03200366
- Testing
- Tailored DVD, Patient Navigation
- Where
- 2 sites in United States
- Volunteers
- 371 people, healthy volunteers welcome
- Sponsor
- Indiana University
Neural Systems, Psychopathology
Psychological Mechanisms of Behavioral Dysregulation
This study is directed toward a better understanding of how the brain regulates emotions and social and antisocial behavior. It will look at the use of the orbital frontal cortex and amygdala of the brain.
- Trial name
- NCT00352456
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
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