Clinical trials: Disorder Heart
ST Elevation Myocardial Infarction
Clinical Trial in Patients Who Have Suffered a Heart Attack and Who Have Undergone Catheterization Treated With Levosimendan
The disease under study is acute coronary syndrome with ST segment elevation, defined as patients presenting chest pain of anginal characteristics of more than 20 minutes of duration, with changes in the electrocardiogram…
- Trial name
- LEVOCEST (NCT03699215)
- Testing
- Levosimendan
- Where
- Spain
- Volunteers
- 184 people
- Sponsor
- Hospital Universitario de Canarias
Atrial Fibrillation (AF)
Developing MRI Technologies for Atrial Fibrillation
To measure image quality of damaged areas of the heart in patients with Atrial fibrillation using the contrast Gadopiclenol vs conventional Gadolinium-based contrast agents(GBCA)
- Trial name
- NCT07083115
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- The Cleveland Clinic
STEMI, NSTEMI
Evaluation of Safety and Efficacy of Two Ticagrelor-based De-escalation Antiplatelet Strategies in Acute Coronary Syndrome
The ELECTRA-SIRIO 2 study is a randomized, multicenter, double-blind, investigator-initiated clinical trial aimed to evaluate safety and efficacy of two ticagrelor-based de-escalation antiplatelet strategies in patients with…
- Conditions
- STEMI, NSTEMI, Unstable Angina
- Trial name
- ELECTRA-SIRIO (NCT04718025)
- Testing
- Ticagrelor 90mg, Ticagrelor 60mg, Aspirin
- Where
- Poland
- Volunteers
- 4,500 people
- Sponsor
- Collegium Medicum w Bydgoszczy
Atrial Fibrillation
Comparison Between "Conventional Monitoring" Versus "Monitoring Via Vitaphone" in the Detection of Post Ablation Atrial Arrhythmias of Paroxysmal Atrial Fibrillation
Atrial fibrillation (AF) is the most common atrial arrhythmia. Ablation of AF is a recent technique, nevertheless, the success rates of ablation vary between 50% and 70% depending on the paroxysmal or persistent nature of AF.
- Trial name
- VITAPHONE (NCT03966976)
- Testing
- ECG monitoring & record, Conventional follow-up
- Where
- France
- Volunteers
- 20 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Mitral Valve Insufficiency, Heart Failure
Effectiveness of Surgical Mitral Valve Repair Versus Medical Treatment for People With Significant Mitral Regurgitation and Non-ischemic Congestive Heart Failure
Mitral regurgitation (MR), also known as mitral insufficiency, is a condition in which the heart's mitral valve, located between two of the heart's main chambers, does not firmly shut, allowing blood to leak backwards within the…
- Trial name
- SMMART-HF (NCT00608140)
- Testing
- Surgical mitral valvuloplasty with placement of annular ring (SMVR), Optimal medical therapy (OMT)
- Where
- 9 sites in United States, Canada
- Volunteers
- 2 people
- Sponsor
- Duke University
Lennox-Gastaut Syndrome, Dravet Syndrome
The Effects of Cannabidiol (CBD) on Electrical and Autonomic Cardiac Function in Children With Severe Epilepsy
The investigators propose to study the effects of cannabidiol (CBD) on cardiac electrical function and the autonomic nervous system in children with Dravet syndrome (DS) and Lennox-Gastaut syndrome (LGS), when the CBD is…
- Trial name
- CBD1 (NCT02815540)
- Testing
- 12-Lead ECG, Cannabidiol
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Gillette Children's Specialty Healthcare
Coronary Artery Disease
The ENIGMA II Trial:Nitrous Oxide Anaesthesia and Cardiac Morbidity After Major Surgery: a Randomised Controlled Trial
To investigate the safety of nitrous oxide (N2O) anaesthesia in patients with risk factors for coronary artery disease undergoing major surgery.
- Trial name
- NCT00430989
- Testing
- Nitrous Oxide, No Nitrous Oxide
- Where
- Australia
- Volunteers
- 7,112 people
- Sponsor
- Bayside Health
Perioperative Period
Treatment of Supraventricular Tachycardia in Patients With Non-cardiac Surgery by Dexmedetomidine
Supraventricular tachycardia (SVT) is a common arrhythmia in the perioperative period, which is associated with adverse stimulus such as cardiovascular risk factors, emotional tension, hypoxia, CO2 accumulation, hypokalemia…
- Trial name
- NCT04284150
- Testing
- Dexmedetomidine; Midazolam;
- Volunteers
- 60 people
- Sponsor
- Lianyungang Hospital Affiliated Bengbu Medical College
Atrial Fibrillation, Quality of Life
The Effect of Walking Exercises in Patients With Atrial Fibrillation
This research will be carried out to determine the effect of walking exercises performed using a behavioral change model on symptom severity and quality of life in patients with Atrial Fibrillation.
- Conditions
- Atrial Fibrillation, Quality of Life, Symptoms and Signs
- Trial name
- NCT05189691
- Testing
- walking exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 78 people
- Sponsor
- Necmettin Erbakan University
Persistant Atrial Fibrillation
Ablation With the PFA System With a Large-Area Focal Catheter for the Treatment of Persistent Atrial Fibrillation
The study evaluates the safety and effectiveness of the investigational QuickShot Nav configuration of the CardioWave System for focal catheter ablation of persistent atrial fibrillation (PerAF).
- Trial name
- Quick AF (NCT07281521)
- Testing
- pulsed field ablation
- Where
- 3 sites in Croatia, Czechia
- Volunteers
- 200 people
- Sponsor
- CardioFocus
Arrhythmogenic Cardiomyopathy, PKP2-ACM
A Study to Assess Real-world Patient Characteristics and Clinical Course for Symptomatic Patients With PKP2-ACM
An observational study to assess real-world patient characteristics and clinical course of disease in participants with PKP2-ACM.
- Conditions
- Arrhythmogenic Cardiomyopathy, PKP2-ACM, PKP2-ARVC
- Trial name
- SNAPSHOT- PKP2 (NCT06976606)
- Where
- 6 sites in United States
- Volunteers
- 40 people
- Sponsor
- Lexeo Therapeutics
Adult Rhabdomyosarcoma, Lung Metastases
Intensity-Modulated Radiation Therapy in Treating Younger Patients With Lung Metastases
This pilot clinical trial studies intensity-modulated radiation therapy (IMRT) in treating younger patients with lung metastases.
- Conditions
- Adult Rhabdomyosarcoma, Lung Metastases, Metastatic Ewing Sarcoma, Previously Treated Childhood Rhabdomyosarcoma
- Trial name
- NCT01586104
- Testing
- intensity-modulated radiation therapy
- Where
- 7 sites in United States
- Volunteers
- 20 people
- Sponsor
- Ann & Robert H Lurie Children's Hospital of Chicago
POX Range of Healthy Newborns at Different Altitudes, POX Threshold for Screening Major CHD in Neonates
POX Range and the Threshold for Screening Major CHD in Neonates at Different Altitudes
major CHD (Congenital Heart Disease) screening by POX (pulse oximetry) in sea-level areas is not fit for low, medium and high altitude areas, but the normal range of pulse oximetry at different altitude areas has not been studied…
- Trial name
- NCT04238104
- Testing
- no intervention
- Where
- 8 sites in China
- Volunteers
- 2,200 people
- Sponsor
- Children's Hospital of Fudan University
Out-Of-Hospital Cardiac Arrest, Myocardial Infarction, Acute
Benefit of Hypothermia in OHCA Complicating AMI
To determine the clinical effectiveness of hypothermia treatment in patients with out-of-hospital cardiac arrest complicating acute myocardial infarction.
- Conditions
- Out-Of-Hospital Cardiac Arrest, Myocardial Infarction, Acute, Hypothermia Neonatal
- Trial name
- Hypothermia (NCT06141252)
- Testing
- Hypothermia
- Where
- South Korea
- Volunteers
- 2,925 people
- Sponsor
- Yonsei University
Coronary Arterial Disease
Optical Coherence Tomography: Prognostic Value and Artificial Intelligence
This study aims to evaluate the prognostic value of optical coherence tomography (OCT) imaging of the coronary arteries. OCT provides high-resolution images of the vessel wall and stented segments during routine cardiac…
- Trial name
- ORANGE (NCT07293858)
- Where
- Netherlands
- Volunteers
- 1,000 people
- Sponsor
- Radboud University Medical Center
Cardiac Arrest, Comatose
Automated Pupillometry for Coma Prognostication After Cardiac Arrest
Background: Sedation and therapeutic hypothermia (TH) delay neurological responses and might reduce the accuracy of clinical examination to predict outcome after cardiac arrest (CA).
- Trial name
- NCT02607878
- Where
- 10 sites in Belgium, France and 6 more
- Volunteers
- 470 people
- Sponsor
- Centre Hospitalier Universitaire Vaudois
Heart Failure, Cardiovascular Risk Factor
Cardiovascular Profiles in Rheumatoid Arthritis
Cardiovascular disease is the leading cause of death in RA patients. This increased risk may be apparent even before the clinical recognition of RA.
- Conditions
- Heart Failure, Cardiovascular Risk Factor, Rheumatoid Arthritis, Myocardium; Injury
- Trial name
- RA-HF (NCT03960515)
- Volunteers
- 400 people
- Sponsor
- Maria Betânia Almeida Dias Ferreira
Cardiac Arrhythmia
Safety of the Colonoscope Magnetic Imaging Device (ScopeGuide®) in Patients With Implantable Cardiac Devices
The Olympus ScopeGuide® is a useful tool in speeding up colonoscopy and making it less painful for patients. It is currently contraindicated by the manufacturer for use with patients with implantable electronic devices (such as…
- Trial name
- NCT01825525
- Testing
- Exposure to ScopeGuide
- Where
- United Kingdom
- Volunteers
- 100 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Physical Activity, Heart Failure
WHISH-2-Prevent Heart Failure
The WHISH-2-Prevent Heart Failure (HF) study is an ancillary study to the Women's Health Initiative Strong and Healthy (WHISH) exercise pragmatic trial.
- Conditions
- Physical Activity, Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure With Normal Ejection Fraction
- Trial name
- NCT03099889
- Testing
- Physical Activity
- Where
- United States
- Volunteers
- 49,936 people, healthy volunteers welcome
- Sponsor
- Memorial Hospital of Rhode Island
Coronary Stenosis
Investigation of the Ringer Perfusion Balloon Catheter (Ringer PTCA)
The objective of this study is to demonstrate safe and effective use of the Ringer perfusion balloon catheter for dilatation/pre-dilatation of coronary stenoses during percutaneous coronary intervention (PCI).
- Trial name
- NCT04862689
- Testing
- Ringer Perfusion Balloon Catheter
- Where
- 7 sites in United States, Canada
- Volunteers
- 60 people
- Sponsor
- Vascular Solutions LLC
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