Clinical trials: Disorder Heart
Cardiogenic Shock
CorVad Myocardial Infarction Complicated with Cardiogenic Shock Trial
Cardiogenic shock a serious complication of a heart attack (myocardial infarction). Despite evaluation of several new treatments during the last decade, the mortality in patients with cardiogenic shock still exceeds 50%.
- Trial name
- Corvad AMICS (NCT06886113)
- Testing
- Conventional circulatory support, CorVad
- Where
- China
- Volunteers
- 269 people, healthy volunteers welcome
- Sponsor
- Shenzhen Core Medical Technology CO.,LTD.
Coronary Artery Disease, Aortic Valve Disease
Robustness Check of Placement and Measurement Algorithms for Blood Flow Measurement on Common Carotid Artery
This study is set up to test the robustness of algorithms and models and to optimize them. Furthermore, data are used to investigate the influence of probe orientation on parameters of the common carotid artery.
- Conditions
- Coronary Artery Disease, Aortic Valve Disease, Mitral Valve Disease
- Trial name
- RAdiUS (NCT05193760)
- Where
- Netherlands
- Volunteers
- 67 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Sinus Bradycardia, Sinus Node Disease
IES-ACap: Influence of Atrial Pulse Width in the Behaviour of ACap™ Confirm Algorithm.
The purpose of this observational study is to collect data regarding the population of patients with a pacemaker implanted.
- Conditions
- Sinus Bradycardia, Sinus Node Disease, Atrio-ventricular Block
- Trial name
- IES-ACap (NCT00832260)
- Volunteers
- 70 people
- Sponsor
- Abbott Medical Devices
Arrhythmia
PORTuguese Research on Telemonitoring With CareLink® (PORTLink)
Compare use of Carelink system - monitoring system - with traditional in-clinic follow up, in patients with implantable cardiac defibrillator (ICD)
- Trial name
- PORTLink (NCT03125382)
- Testing
- Carelink System, In office standard visit
- Where
- 6 sites in Portugal
- Volunteers
- 141 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
Atrial Fibrillation (AF)
Optimal Shock Energy for Electrical Cardioversion of Atrial Fibrillation
Introduction For elective electrical cardioversion of atrial fibrillation, the recommended standard is the administration of a biphasic direct current shock.
- Trial name
- NCT07610980
- Testing
- Direct current biphasic electrical cardioversion, blood sampling
- Where
- Czechia
- Volunteers
- 400 people
- Sponsor
- Motol and Homolka University Hospital
Heart Failure
Clinical Data Collection Study Using CPM System
This study will assess the deployment of the ADI CPM System in a home setting and determine the interoperability of the CPM System within existing care pathways for HF patients.
- Trial name
- NCT06007079
- Testing
- CPM Device
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Analog Device, Inc.
Coronary Artery Disease
In Stent ELUTES Study
This trial will compare the long term safety and effectiveness of the V Flex Plus PTX Drug Eluting coronary stent with conventional treatment for in-stent restenosis for coronary arteries.
- Trial name
- ELUTES II (NCT00225680)
- Testing
- drug eluting coronary stent
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Cook Group Incorporated
Platelet Aggregation During Acute Myocardial Infarction
DPP-4 Inhibitors and Acute Myocardial Infarction:Effects on Platelet Function
Cardiovascular events are the main cause of mortality in diabetic patients ,on the other hand,during an acute myocardial infarction(AMI),hyperglycemia increases mortality and is related to different pathophysiologic processes.
- Trial name
- NCT02377388
- Testing
- sitagliptin OR saxagliptin
- Where
- Brazil
- Volunteers
- 74 people
- Sponsor
- University of Sao Paulo General Hospital
Acute Heart Failure (AHF), Pulmonary Embolism (Diagnosis)
Pulmonary Embolism in Patients With Acute Heart Failure (PEHF Study)
This study focuses on two serious and common medical conditions: heart failure and pulmonary embolism (a blood clot in the lungs).
- Conditions
- Acute Heart Failure (AHF), Pulmonary Embolism (Diagnosis), Venous Thromboembolism
- Trial name
- PEHF (NCT07499661)
- Testing
- Systematic screening for pulmonary embolism in all patients using a guideline-recommended diagnostic algorithm
- Where
- 10 sites in France
- Volunteers
- 740 people
- Sponsor
- University Hospital, Angers
Hypersalivation, Prevention of Drooling
Efficacy of Intravenous Glyco-P® in Patients Undergoing Procedure That Require Anesthesia Service
This observational study was designed to prove clinical efficacy of the well known "glycopyrrolate" which is considered an orphan drug in Thailand.
- Conditions
- Hypersalivation, Prevention of Drooling, Bradycardia, Reversal of Muscle Relaxants
- Trial name
- NCT02102542
- Where
- Thailand
- Volunteers
- 65 people
- Sponsor
- Mahidol University
Myocardial Infarction, Cardiac Rehabilitation
Post Myocardial Infarction's Rehabilitation Guided by Heart Rate Variability
Cardiac rehabilitation reduces morbidity and mortality after myocardial infarction (MI) and improve the sympathovagal balance. The autonomic nervous system (ANS) can be explored by the variation of heart rate (HRV).
- Trial name
- HRV REEDUC (NCT03745742)
- Testing
- HRV measurement
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Clermont-Ferrand
Heart Failure, Cardiac Imaging Techniques
MRI to Predict Rejection and Failure in Transplant and Cardiomyopathy Patients
Overall Research Strategy of this protocol is to refine and validate noninvasive CMR imaging sequences with invasive hemodynamic and pathology results to create a comprehensive, noninvasive, radiation-reduced regimen for…
- Conditions
- Heart Failure, Cardiac Imaging Techniques, Congenital Heart Defects
- Trial name
- NCT03822442
- Where
- United States
- Volunteers
- 113 people
- Sponsor
- Children's National Research Institute
Coronary Artery Disease, Multi Vessel Coronary Artery Disease
Safety Study of Acellular Tissue Engineered Vessel for Coronary Artery Bypass
To assess safety and feasibility of a coronary bypass created with Vascudyne Acellular Tissue Engineered Vessel (ATEV) with External Support Structure (ESS) in patients requiring multi vessel coronary artery bypass grafting…
- Trial name
- VCAB-2 (NCT07078370)
- Testing
- ATEV with ESS
- Where
- 4 sites in Poland
- Volunteers
- 20 people
- Sponsor
- Vascudyne, Inc.
Acute Coronary Syndrome
Platelet Reactivity Inhibition Following Ticagrelor Loading Dose and One Year Outcome
This study will try to determine if the measure of the platelet reactivity of the patients receiving from the ticagrelor continuation in an acute coronary syndrome handled by coronary angioplasty allows to predict the hemorrhagic…
- Trial name
- NCT02428725
- Testing
- blood sample
- Where
- France
- Volunteers
- 640 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
HEART FAILURE
Heart Failure STratification and OutcomeS
Background: Heart failure (HF) is in many cases the final way for coronary heart diseases. In older than 65 years is the most important cause of hospitalization.
- Trial name
- HEFESTOS (NCT02444676)
- Testing
- Stratification and outcomes
- Where
- Spain
- Volunteers
- 560 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Supraventricular Tachycardia
Adenosine Versus Verapamil for Management of Supraventricular Tachycardia Post- Coronary Artery Bypass Grafting
This prospective study was conducted in 268 patients aged from 65-70 years posted for coronary artery bypass grafting. Patients were randomly allocated to either adenosine or verapamil(control) groups.
- Trial name
- NCT04203368
- Testing
- adenosine, verapamil
- Where
- Egypt
- Volunteers
- 268 people
- Sponsor
- Ain Shams University
Fibromuscular Dysplasia of Arteries, Fibromuscular Dysplasia
Survey on Physical Activity and Qualify of Life in Fibromuscular Dysplasia
Fibromuscular dysplasia (FMD) is a disease of the arteries that is not due to plaque build-up or inflammation. While some patients with FMD are health, some may experience heart attacks, strokes, aneurysms or blood vessel…
- Conditions
- Fibromuscular Dysplasia of Arteries, Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection
- Trial name
- NCT07529691
- Where
- United States
- Volunteers
- 2,000 people
- Sponsor
- Vanderbilt University Medical Center
Acute Myocardial Infarction (AMI)
Using Advanced CT Scans and Blood Markers to Better Understand Heart Damage and Recovery After a Heart Attack
Acute myocardial infarction with ST-segment elevation (STEMI) remains a leading cause of morbidity and mortality worldwide. Although advances in reperfusion therapy have reduced early mortality, many patients later develop…
- Trial name
- NCT07268391
- Testing
- Blood analysis, spectral CT scan and cardiac magnetic resonance imaging (CMR) study, Blood analysis and spectral CT study
- Where
- 4 sites in Spain
- Volunteers
- 95 people
- Sponsor
- Instituto de Investigación Biomédica de Salamanca
Acute Coronary Syndrome
A Study to Evaluate the Safety of Apixaban in Acute Coronary Syndrome (ACS) Japanese Patients
The purpose of this study is to assess the bleeding safety (the composite endpoint of major and clinically relevant non-major bleeding) of 2 doses of apixaban (2.5 mg BID and 5.0 mg BID) or placebo in combination with standard…
- Trial name
- NCT00852397
- Testing
- Apixaban
- Where
- 18 sites in Japan
- Volunteers
- 151 people
- Sponsor
- Pfizer
Tricuspid Regurgitation
Laplace Early Feasibility Study - Canada
The objective of the study is to assess the safety and technical feasibility of the Laplace Transcatheter Tricuspid Valve Replacement (TTVR) System
- Trial name
- NCT07171060
- Testing
- Laplace TTVR System
- Where
- 3 sites in Canada
- Volunteers
- 15 people
- Sponsor
- Laplace Interventional, Inc
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