Clinical trials: Disorder of Endocrine Ovary
Polycystic Ovary Syndrome
PCOS Indirect and Intangible Economic Burden
The primary purpose of the PCOS Indirect and Intangible Economic Buren study is to estimate the economic costs of having PCOS in terms of quality of life and work productivity.
- Trial name
- PCOSCHALLENGE (NCT05903404)
- Where
- United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
Polycystic Ovary Syndrome, Infertility, Female
Comparison of Ovulation Induction Cycle Outcomes Between Early and Late Dose Increments for Low Dose Gonadotropin Step-up Protocol Among Infertile Women Diagnosed With Polycystic Ovary Syndrome: Prospective Randomised Trial
Low dose gonadotropin step-up ovulation induction treatment is the universally accepted and utilized teratment protocol for infertile women diagnosed with polycystic ovary syndrome (PCOS).
- Trial name
- NCT04528849
- Testing
- Gonadotropin dose increment timing
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
PCOS (Polycystic Ovary Syndrome)
The Aim of This Study is to Gain Insight Into the Occurrence of Irritable Bowel Symptoms During Ovarian Stimulation in Individuals With PCOS and in Women Who Wish to Freeze Their Eggs. This Study Uses Questionnaires.
This exploratory study investigates the impact of fertility treatments on symptoms of irritable bowel syndrome (IBS) in women. Specifically, the study focuses on two groups: Women with polycystic ovary syndrome (PCOS) who are…
- Trial name
- FIBS (NCT07533968)
- Testing
- questionnaires
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Polycystic Ovary Syndrome
Awareness Of Gynecologists About Role Of Physical Therapy In Management Of Polycystic Ovarian Syndrome
This study aimed to measure the extent of knowledge of gynecologists about the role of physical therapy in the management of PCOS.
- Trial name
- NCT06543225
- Testing
- No intervention
- Where
- Egypt
- Volunteers
- 399 people, healthy volunteers welcome
- Sponsor
- Cairo University
Polycystic Ovary Syndrome
Plant Exosomes and Patients Diagnosed With Polycystic Ovary Syndrome (PCOS) 17
The purpose of this study is to see if substances contained in ginger or aloe plants, called exosomes, will treat and improve the condition polycystic ovary syndrome
- Trial name
- NCT03493984
- Testing
- Ginger exosomes, Aloe exosomes
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
PCOS (Polycystic Ovary Syndrome)
Effects of Folic Acid and Vitamin E on Hormones in Polycystic Ovary Syndrome
The goal of this prospective comparative interventional study is to evaluate serum Ezrin levels and investigate the effects of one-month supplementation with vitamin E and folic acid in Iraqi women of reproductive age diagnosed…
- Trial name
- NCT07723443
- Testing
- Vitamin E 400, Folic Acid 5 Mg Oral Tablet
- Where
- Iraq
- Volunteers
- 207 people, healthy volunteers welcome
- Sponsor
- Al-Mustansiriyah University
In Vitro Fertilization
Corifollitropin Alfa Application in PCOS Patients
Corifollitropin alfa, single dose administered sustains multiple follicular development for 7 days. However, It may induce ovarian hyperstimulation syndrome (OHSS), especially in high responder women such as patients of…
- Trial name
- NCT02215135
- Testing
- Corifollitropin alfa
- Where
- Taiwan
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Polycystic Ovary Syndrome
Efficacy of Letrozole Versus Clomiphene Citrate on Ovulation Induction in Patients With Polycystic Ovarian Syndrome
We aimed this study to determine and compare frequency of induction of ovulation in women with polycystic ovarian syndrome treated with Letrozole versus clomiphene citrate as published literature shows variations.
- Trial name
- NCT05075863
- Testing
- Letrozole
- Where
- Pakistan
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Nishtar Medical University
Polycystic Ovary, Depression
The Effect of Polycystic Ovary Syndrome Phenotypes on Quality of Life and Sexual Function
This study was planned to examine whether different phenotypes of PCOS have an effect on quality of life, depression inventory and sexual function.
- Conditions
- Polycystic Ovary, Depression, Sexual Dysfunction
- Trial name
- PCOS (NCT06428786)
- Testing
- Female Sexual Function Index
- Where
- Turkey (Türkiye)
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Polycystic Ovary Syndrome
To Study the Effect of SC-FOS Prebiotics in Women With Polycystic Ovary Syndrome
The purpose of this study is to determine if there is a difference in the clinical characteristics of patients with polycystic ovary syndrome after the administration of SC-FOS in the enteral diet compared to patients with a…
- Trial name
- NCT05999097
- Testing
- Short Chain Fructooligosaccharides
- Where
- Mexico
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Chihuahua
Polycystic Ovary Syndrome
The PCOS Challenge Study
The primary purpose of The PCOS Challenge Study will be to conduct high-quality research where patients are included in the design, and answering the questions that patients identify as important to their lived experience with…
- Trial name
- PCOSCHALLENGE (NCT05797909)
- Where
- United States
- Volunteers
- 15,000 people, healthy volunteers welcome
- Sponsor
- PCOS Challenge: The National Polycystic Ovary Syndrome Association
Polycystic Ovary Syndrome (PCOS)
Androgen Excess as a Cause for Adipogenic Dysfunction in PCOS Women
The purpose of this research study is to collect specimen samples and study medical information from women with Polycystic Ovary Syndrome (PCOS) and women without PCOS.
- Trial name
- NCT01889199
- Testing
- Flutamide
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Polycystic Ovary Syndrome
Effect of Ramadan Fasting on Ovulation and Insuline Resistance in Patients With PCOS
Polycystic ovary syndrome (PCOS) has a heterogeneous clinical presentation comprising reproductive (hyperandrogenism, menstrual irregularity, anovulation, infertility, pregnancy complications), metabolic [insulin resistance (IR)…
- Trial name
- NCT02499289
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Polycystic Ovarian Syndrome, Obesity
Post-Prandial Liver Glucose Metabolism in PCOS
The Investigators will measure if hepatic metabolism is upregulated in obese girls with PCOS and hepatic steatosis (HS), compared to PCOS without HS and obese controls without HS.
- Conditions
- Polycystic Ovarian Syndrome, Obesity, Hepatic Steatosis
- Trial name
- PLUM (NCT03041129)
- Testing
- oral glucose tolerance test, MRI of liver
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Polycystic Ovary Syndrome
Treatment of Hyperandrogenism Versus Insulin Resistance in Infertile Polycystic Ovary Syndrome (PCOS) Women
The goal of this three-armed randomized controlled trial is to establish the relative roles of treatment of hyperandrogenism versus obesity (as the largest modifiable factor contributing to insulin resistance) in treating…
- Trial name
- OWL-PCOS (NCT00704912)
- Testing
- Orlistat/Meal Replacement/Lifestyle Modification, Loestrin 1/20, Combination of treatments
- Where
- 2 sites in United States
- Volunteers
- 217 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
In Vitro Fertilization, Polycystic Ovary Syndrome
Comparative Study of Long-acting and Short Acting Triptorelin in PCOS Patients Who Underwent IVF/ICSI
To test whether long-acting Triptorelin on pituitary down-regulation can improve the clinical pregnancy rate and reduces the incidence of ovarian hyperstimulation syndrome (OHSS) in infertile high-risk patients with polycystic…
- Trial name
- NCT02477566
- Testing
- Long-acting Triptorelin, Short-acting Triptorelin
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nanjing University
Ovarian Cysts
Ultrasonographic Evaluation of Ovarian Stromal Vascularity in Women With Polycystic Ovary Syndrome (PCOS)
The most common endocrine condition in reproductive women is polycystic ovary syndrome. It has a prevalence of 5-10%. According to the Rotterdam criteria, oligo/anovulation, clinic or biochemical hyperandrogenism, PCOS morphology…
- Trial name
- NCT05418595
- Where
- Turkey (Türkiye)
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Usak State Hospital
Oligomenorrhea, Amenorrhea
Ultrasound Characterization of Ovarian Follicle Dynamics in Women With Amenorrhea
In women with regular menstrual cycles, antral follicles have been shown to grow in synchronous cohorts, called waves, 2-3 times in a menstrual cycle.
- Conditions
- Oligomenorrhea, Amenorrhea, Polycystic Ovary Syndrome (PCOS)
- Trial name
- NCT01927432
- Where
- United States
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Cornell University
AMH, Diet Habit
Effect of Antimullerian Hormone Levels on the Inflammatory Index, Phytochemical Index and NRF Nutrient Density
The aim of the study was to calculate the dietary inflammatory index, dietary phytochemical index and NRF nutrient density of the dietary pattern routinely consumed by women and to assess whether there is a difference between…
- Conditions
- AMH, Diet Habit, Ovarian Failure, Polycystic Ovary Syndrome
- Trial name
- AMH (NCT06426771)
- Testing
- Dietary Inflammatory Index, hormone profile
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Etlik Zubeyde Hanım Women's Health Care, Training and Research Hospital
Polycystic Ovary Syndrome, c Type Natriuretic Peptide
Comparison of Serum C Type Natriuretic Peptide Levels Between Polycystic Ovary Syndrome Patients and Healthy Women
Recent studies have shown that C natriuretic peptide is produced from granulosa cells, increasing cumulative guanosine monophosphate (cGMP) production by affecting cumulus cells through natriuretic peptide receptors.
- Conditions
- Polycystic Ovary Syndrome, c Type Natriuretic Peptide, Menstrual Irregularity, Hyperandrogenism
- Trial name
- CNP (NCT04006171)
- Testing
- C type natriuretic peptide
- Where
- Cyprus
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Near East University, Turkey