Clinical trials: Disorder of Vein
Venous Thrombosis
The Use of NMES as a Home-based Therapy Following Total Knee Arthroplasty
The use of neuromuscular electrical stimulation (NMES) as a home-based therapy following total knee arthroplasty. Measures of interest: lower limb venous hemodynamics, joint range of motion, lower limb swelling, walking speed…
- Trial name
- NCT02343198
- Testing
- Custom-built research muscle stimulator
- Where
- Ireland
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National University of Ireland, Galway, Ireland
Vein Collapse, Vein Thrombosis
TenTaTorch: Venepuncture Made Easy
Venepuncture can be challenging, especially in patients with co-morbidities that predispose them to have inaccessible veins. Multiple unsuccessful venepuncture attempts compromise patient care.
- Conditions
- Vein Collapse, Vein Thrombosis, Vein; Tortuous, Vein Disease
- Trial name
- NCT03202238
- Testing
- Conventional, Veinlite, TenTaTorch
- Where
- Singapore
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Primary Open Angle Glaucoma, Normal Tension Glaucoma
Correlation of Orbital Cerebrospinal Fluid Pressure and Retinal Venous Outflow in Primary Open-angle Glaucoma
A spontaneous venous pulsation over the optic disc is an ophthalmological sign that can potentially be found in up to 98% of healthy individuals.
- Trial name
- NCT01795014
- Where
- Belgium
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Malaria
PfSPZ Vaccine: Dose Optimization With Heterologous Challenge in Healthy Malaria-Naïve Adults
This is an open-label evaluation of the safety, tolerability, immunogenicity and efficacy of PfSPZ Vaccine administered by direct venous inoculation (DVI) in healthy, malaria-naïve adult subjects.
- Trial name
- NCT02601716
- Testing
- PfSPZ Vaccine, CHMI (7G8), CHMI (NF135.C10)
- Where
- 2 sites in United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Sanaria Inc.
Sepsis, Sepsis and Septic Shock
Hemodynamic Venous Congestion Ultrasound (VExUS) by ICU Nurses in Sepsis Patients.
Sepsis is a serious condition where the body's immune response to infection overreacts, leading to organ damage and death. Venous congestion, a buildup of blood in the veins, can occur in sepsis and contribute to organ injury.
- Conditions
- Sepsis, Sepsis and Septic Shock, Sepsis at Intensive Care Unit, Intensive Care Nurses
- Trial name
- VEXIVAN (NCT07406750)
- Testing
- Education in performing hemodynamic diagnostic ultrasound of venous congestion, Hemodynamic diagnostic ultrasound of venous congestion
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Region Örebro County
Diabetic Foot, Leg Ulcer
Obtaining and Storing Standard of Care Wound Biopsies for Immediate or Future Wound-Related Scientific Study
The objective of this study protocol is to use wound biopsies that have been obtained during standard of care management for further scientific evaluation after standard evaluation by a pathologist.
- Conditions
- Diabetic Foot, Leg Ulcer, Decubitus Ulcer
- Trial name
- NCT00759889
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southwest Regional Wound Care Center
Anticoagulants; Circulating, Hemorrhagic Disorder
MEdication Counselling Models for Outpatient oRal antIcoaguLation
The goal of this clinical trial is to investigate whether telepharmacy-led counselling can improve medication adherence, knowledge, and hospitalisation/mortality compared with pharmacist-led counselling in adult outpatients…
- Trial name
- MEMORIAL (NCT06290440)
- Testing
- Telepharmacy-led counselling, Pharmacist-led counselling
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Gia Dinh People Hospital
Diabetic Retinopathy, Retinal Vein Occlusion
Computer Aided Diagnosis of Multiple Eye Fundus Diseases From Color Fundus Photograph
Blindness can be caused by many ocular diseases, such as diabetic retinopathy, retinal vein occlusion, age-related macular degeneration, pathologic myopia and glaucoma.
- Conditions
- Diabetic Retinopathy, Retinal Vein Occlusion, Retinal Artery Occlusion, Central Serous Chorioretinopathy
- Trial name
- NCT04723160
- Testing
- Software assisted imaging diagnosis
- Where
- 5 sites in China
- Volunteers
- 748 people, healthy volunteers welcome
- Sponsor
- Visionary Intelligence Ltd.
Deep Vein Thrombosis, Pulmonary Embolism
Venous Blood Flow Velocity: Electrical Foot Stimulation Compared to Intermittent Pneumatic Compression of the Foot
Electrical stimulation of the foot can increase blood flow out of the leg. This increased blood flow can prevent blood clots from forming in the leg veins.
- Trial name
- NCT00114608
- Testing
- The Focus™ Neuromuscular Stimulation System
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University at Buffalo
Deep Vein Thrombosis, Deep Venous Insufficiency
A Study of Modified Limb Braking and Early Bed Mobility Strategies After Femoral Venipuncture Intervention
The goal of this clinical trial is to compare in describe participant population health conditions. The main questions it aims to answer are: To obtain the limb movement and bed mobility limits after femoral venipuncture, in…
- Trial name
- NCT05900622
- Testing
- Reduced postoperative braking and bed rest time.Lower extremity on the puncture side with a 2-hour brake+Get out of bed after 4 hours, Significantly reduce postoperative braking and bed rest time.No braking of the lower limb on the side of the puncture+Get out of bed after 2 hours
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tong Zhu
Venous Thrombosis
Phase I Study of Direct Coagulation Factor Xa Inhibitor SYHA136 Tablets in Chinese Healthy Volunteers
The trial used single-center, randomized, double-blind, placebo-controlled, single-dose ascending study. The trial planned to enroll fifty-six healthy volunteers.
- Trial name
- NCT04036656
- Testing
- SYHA136 0.5 mg, SYHA136 1 mg, SYHA136 2.5 mg
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- CSPC ZhongQi Pharmaceutical Technology Co., Ltd.
Hematological Diseases, Healthy Volunteers
Capillary and Venous Blood Count Parameters
The purpose of this study is to compare capillary blood count parameters with the corresponding venous samples to verify the hypothesis that capillary and venous blood count parameters are equivalent.
- Trial name
- NCT00390988
- Testing
- blood sampling
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- University of Magdeburg
Venous Thromboembolism, Deep Venous Thrombosis
Prevalence and Risk Factors of Venous Thromboembolism in Hospitalized Pediatric Patients
The issue to be studied is the prevalence of venous thromboembolism (VTE) in hospitalized pediatric patients, and to identify if there are subgroups of patients who may be at higher risk.
- Conditions
- Venous Thromboembolism, Deep Venous Thrombosis, Pediatrics
- Trial name
- pediatric DVT (NCT01140386)
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Penn State University
Healthy Volunteers, Heart Failure
A Study Understanding How Much CDR132L Enters the Bloodstream After Injection Under the Skin Compared to Injection Into a Vein in Healthy Participants
This study is being done to understand how much of the medicine (CDR132L) enters the bloodstream after injection under the skin compared to injection into a vein in healthy people.
- Trial name
- NCT07656454
- Testing
- CDR132L (i.v.), CDR132L (s.c.)
- Where
- Germany
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Lower Extremity Deep Venous Thrombosis
Comparison of Subcutaneous Heparin and Enoxaparin for Deep Venous Thrombosis (DVT) Prophylaxis in Surgical Intensive Care Patients
Study hypothesis: Subcutaneous enoxaparin is more effective than subcutaneous heparin in preventing the development of DVT in the general surgical intensive care unit population.
- Trial name
- NCT01325779
- Testing
- heparin, enoxaparin
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Lisa Louwers
Venous Sinus Thrombosis, Cranial
Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals
The anatomical characteristics of veins and venous sinus result in great differences between cerebral venous system diseases and cerebral artery diseases in etiology, pathophysiology and clinical features.Therefore, understanding…
- Trial name
- NCT05413837
- Testing
- anotomy and variation of venous sinus, the level of biomarker in bood
- Where
- China
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Retinopathy, Retinal Vein Occlusion
Feasibility and Safety of MB-102 in Ocular Angiography as Compared to Fluorescein Sodium
The objective of this study is to evaluate the safety and image quality of the investigational dye, MB-102, compared to the control dye (fluorescein sodium) in healthy and diseased eyes using fluorescent angiography for retinal…
- Conditions
- Retinopathy, Retinal Vein Occlusion, Diabetic Retinopathy, Macular Degeneration
- Trial name
- NCT04008121
- Testing
- Fluorescein sodium and Zeiss FF450 fundus camera, MB-102 and Zeiss FF450 fundus camera, Fluorescein sodium and commercially available optical angiography imaging system
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- MediBeacon
Deep Venous Thrombosis, Colonic Cancer
Chemoprophylaxis With Rivaroxaban for Lower Limb Deep Vein Thrombosis in Colorectal Cancer
The chemoprophylaxis of deep vein thrombosis (DVT) with subcutaneous low-molecular-weight heparin (enoxaparin) in the postoperative period of elective surgeries is already well established in the literature and in clinical…
- Trial name
- Ésquilo (NCT05303818)
- Testing
- Rivaroxaban 10 MG
- Where
- Brazil
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Hospital do Servidor Publico Estadual
Intrauterine Growth Retardation (IUGR)
Reproducibility of the Measurement of the Right Portal Vein Diameter
Although routine ultrasound is offered during the third trimester of pregnancy, less than a quarter of newborns with intrauterine growth retardation (IUGR) are suspected antenatally.
- Trial name
- PORTALGROWTH1 (NCT04617964)
- Testing
- Ultrasound
- Where
- France
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Healthy
Effects of Miconazole on Blood Flow
This study will investigate the effect of the drug miconazole on blood vessel dilation. Miconazole stops production of EDHF, a substance that causes arteries to dilate. EDHF is produced by the cells that line blood vessels.
- Trial name
- NCT00004575
- Testing
- Miconazole, L-NMMA, Bradykinin
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)