Clinical trials: Disorders of Balance
Parkinson's Disease (PD), Healthy Aging
Exoskeleton-Assisted Mobility in Aging and in Parkinson's Disease
This study will evaluate whether a wearable robotic exoskeleton can improve mobility, balance, and walking in healthy older adults and in individuals living with Parkinson's disease, populations at high risk of falls and mobility…
- Trial name
- NCT07567482
- Testing
- Exoskeleton
- Where
- Canada
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Centre intégré de santé et de services sociaux de l'Outaouais
Stroke
Influences of Cane Use on Voluntary Forward Stepping Movement and Associated Attentional Demands in Hemiplegic Patients
The purpose of this study was to examine the influence of cane use on the movement, kinetics, and associated attentional demands of performing a voluntary forward stepping movement in patients with stroke and age-matched healthy…
- Trial name
- NCT00172146
- Where
- Taiwan
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Adolescent, Foot Posture Index Score
Relationship Between Foot Posture, Toe Flexor Strength, and Balance in Adolescents
The foot plays a critical role in movement and postural control, with toe flexor strength linked to gait, performance, and stability. While these relationships are well studied in adults, evidence in adolescents is limited.
- Conditions
- Adolescent, Foot Posture Index Score, Toe Flexor Strength, Flat Foot Acquired Bilateral (Pes Planus)
- Trial name
- NCT07132424
- Testing
- Assesment
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Istanbul Kültür University
Alzheimer's Disease
Study to Evaluate the Effects of Food Ingestion on the Pharmacokinetics of CHF 5074 in Healthy Young Male Subjects
To evaluate the effects of a high-calorie high-fat meal on the extent and rate of absorption of CHF 5074 after single oral administration in young healthy male volunteers.
- Trial name
- CT03 (NCT01258452)
- Testing
- CHF 5074, CHF 5974
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- CERESPIR
Accidental Fall, Postural Balance
The Relation Between Movement Patterns, Balance Performance, Function of the Inner Ear and Falls
Falls are one of the most common reasons for immobilisation and death in elderly population. This study aims at studying falls among a group of older people.
- Conditions
- Accidental Fall, Postural Balance, Movement Disorders in Old Age
- Trial name
- NCT03503916
- Where
- Sweden
- Volunteers
- 113 people, healthy volunteers welcome
- Sponsor
- Lund University
Multiple Sclerosis
Telerehabilitation Based Motor Imagery and Action Observation Training in Multiple Sclerosis
This study aims to investigate the effects of the treatment combination consisting of motor imagery and action observation therapy on balance, functional mobility, lower extremity muscle strength, fatigue and quality of life.
- Trial name
- NCT06295601
- Testing
- Traditional rehabilitation, Action observation therapy and motor imagery
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Inonu University
Type 2 Diabetes
Metabolic Causes of Thrombosis in Type 2 Diabetes Mellitus
The purpose of this study is to learn more about why patients with diabetes have increased heart attacks, strokes and other illnesses due to blood clots causing blockage of a blood vessel.
- Trial name
- NCT00829699
- Testing
- euinsulinemic euglycemic glucose clamp, euinsulinemic hyperglycemic glucose clamp, Hyperinsulinemic euglycemic glucose clamp
- Where
- United States
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
NASH With Fibrosis
Single Dose ADME Study of [14C]-Rencofilstat in Healthy Male Subjects
This is a single-center, single-period, single-dose, open-label, non-randomized study to assess the mass balance recovery, metabolite profile and metabolite identification of 14C- labelled rencofilstat ([14C] CRV431).
- Trial name
- NCT05737433
- Testing
- [14C]-rencofilstat 225mg
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Hepion Pharmaceuticals, Inc.
Chronic Kidney Disease
Analysis of Calcium Balance in Chronic Kidney Disease
Subjects with normal kidney function are able to excrete in their urine the calcium and phosphorus absorbed via the gastrointestinal tract and are thereby are able to maintain calcium and phosphorus balance.
- Trial name
- NCT00974532
- Testing
- High calcium diet 2000 mg/day, Low calcium diet, 800 mg/day
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Fasting State
Bioequivalence Study of Lamotrigine Tablets 25 mg (2 x 25 mg Tablets) Under Fasting Condition
This is an open Label, randomized, two-period, two-treatment, two-sequence, crossover, balanced, single dose pivotal study. The purpose of this study is to assess the bioequivalence between Test Product and the corresponding…
- Trial name
- NCT01618799
- Testing
- Lamotrigine Tablets 25 mg, Lamotrigine
- Where
- India
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- IPCA Laboratories Ltd.
Pulmonary Arterial Hypertension
Absorption, Distribution, Metabolism and Excretion of BIA 5-1058
the purpose of this study is: to determine the rate and routes of excretion of BIA 5-1058 and the mass balance in urine, feces and exhaled air, after a single oral dose of 400 mg 14C labeled BIA 5 1058 containing 3.7…
- Trial name
- ADME (NCT04991181)
- Testing
- 400 mg BIA 5-1058
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Bial - Portela C S.A.
Diabetic Foot
BE STUDY OF METFORMIN GSK 1000mg
A randomized, balanced, open label, crossover, two period, two treatment, two sequence, single dose, oral bioequivalence study under fasting condition.
- Trial name
- BA/BE 199/11 (NCT01710553)
- Testing
- Glucophage 1000mg, Metformin GSK 1000mg
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Fed
Bioequivalence Study of Metoprolol Succinate Extended Release Tablets 200 mg Under Fed Conditions
This is an open Label, randomized, two-period, two-treatment, two-sequence, crossover, balanced, single dose pivotal study. The purpose of this study is to assess the bioequivalence between Test Product and the corresponding…
- Trial name
- NCT01884909
- Testing
- Metoprolol Succinate ER Tablet 200 mg, 'TOPROL-XL®' ER Tablets 200 mg
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- IPCA Laboratories Ltd.
Diabetes Mellitus, Type 2
Combined Effects of BT With Moderate Intensity Aerobic Versus RT in Type 2 DM.
A randomized control trail will be conducted at Social Security Teaching Hospital, Multan Road, Lahore. Social Security Teaching Hospital Shah rah, Lahore.
- Trial name
- NCT06461871
- Testing
- BALANCE TRAINING WITH MODERATE INTESITY AEROBIC VERSUS RESISTED TRAINING (RT), Moderate intensity resistance exercises in combination with balance training
- Where
- Pakistan
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Healthy
"Beverage Hydration Index" of Commercial Therapeutic Beverages
The "beverage hydration index" (BHI) assesses the hydration potential of any consumable fluid relative to water. The BHI is a relatively new metric.
- Trial name
- NCT03262597
- Testing
- enterade, Pedialyte, Gatorade
- Where
- United States
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Sonoma State University
Lumbar Disc Herniation, Lumbar Degenerative Disease
Multivariate Analysis and Risk Factors Were Used to Predict the Short-term Postoperative Pain of Degenerative Lumbar Spine
The objective of this retrospective clinical study wasto study the risk factors for short-term low back and leg pain after PLIF in patients with lumbar Degenerative disease, and to establish a risk prediction model for short-term…
- Conditions
- Lumbar Disc Herniation, Lumbar Degenerative Disease, Sarcopenia
- Trial name
- NCT06628583
- Testing
- Magnetic Resonance Imaging with Contrast
- Where
- China
- Volunteers
- 936 people, healthy volunteers welcome
- Sponsor
- Hao Liu
Pilates Exercise, Gastro Esophageal Reflux
Effects of Clinical Pilates Exercises on Symptoms, Posture, Balance and Quality of Life in GERD
This randomized, single-blind, parallel-group clinical trial investigates whether a six-week supervised clinical Pilates exercise program improves reflux symptom severity, postural alignment, dynamic balance, sleep quality…
- Trial name
- NCT07573280
- Testing
- Usual Daily Activity (No Exercise Intervention), Supervised Clinical Pilates Exercise Training
- Where
- Turkey (Türkiye)
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Istinye University
Cerebral Palsy, Diplegic Cerebral Palsy
The Relationship Between Upper Extremity Functionality, Trunk Control and Balance in Children With Cerebral Palsy
The aim of this study is to examine the relationship between trunk control, upper extremity functionality and balance in children with cerebral palsy and to compare this relationship with healthy sedentary children.This study is…
- Conditions
- Cerebral Palsy, Diplegic Cerebral Palsy, Balance; Distorted
- Trial name
- NCT06378723
- Testing
- Balance Tests
- Where
- 2 sites in Cyprus, Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Obesity, Overweight
Balance: A Pragmatic Trial of a Digital Health Intervention to Prevent Weight Gain in Primary Care
Up to 50% of obese patients are not interested in, or ready for, weight loss. Clinical practice guidelines clearly recommend that these patients avoid gaining weight.
- Conditions
- Obesity, Overweight, Overnutrition, Nutrition Disorders
- Trial name
- D0479 (NCT03003403)
- Testing
- Intervention Program
- Where
- United States
- Volunteers
- 443 people, healthy volunteers welcome
- Sponsor
- Duke University
Autism Spectrum Disorder
Modulation of the Brain Excitatory/Inhibitory (E/I) Balance in Autism Spectrum Disorder (ASD)
This study investigates the brain response to a single acute dose of Arbaclofen, the R-enantiomer of the GABA-B agonist Baclofen, compared to a single dose of placebo in healthy men with and without autism spectrum disorder.
- Trial name
- NCT03594552
- Testing
- Arbaclofen_15, Arbaclofen_30
- Where
- United Kingdom
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- King's College London