Clinical trials: Disorders of Balance
Healthy
Bioequivalence Study of Cyclobenzaprine Hydrochloride 10 mg Tablets, USP Under Fasting Conditions
To compare the single-dose oral bioavailability of Cyclobenzaprine hydrochloride 10 mg tablet of Ohm Labs Inc (A subsidiary of Ranbaxy Pharmaceuticals Inc USA.) with Flexeril® 10 mg tablet (containing Cyclobenzaprine…
- Trial name
- NCT00778037
- Testing
- Cyclobenzaprine hydrochloride 10 mg tablet
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Fasting
Bioequivalence Study of Risperidone Tablet 1 mg Under Fasting Condition
This is a randomized, open Label, balanced, two-treatment, two-period, two-sequence, single dose, crossover pivotal study. The purpose of this study is to assess the bioequivalence between Test Product and the corresponding…
- Trial name
- NCT01722201
- Testing
- Risperidone Tablet 1 mg, Risperidone
- Where
- India
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- IPCA Laboratories Ltd.
Vaginal Infection, ASC-US
Probiotic Implementation as Help in Solving Vaginal Infections
Over recent years, a growing interest has developed in microbiota and in the concept of maintaining a special balance between Lactobacillus and other bacteria species in order to promote women's well-being.
- Trial name
- NCT03372395
- Testing
- Lactobacillus rhamnosus BMX 54
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Roma La Sapienza
Diabetes Mellitus, Oxidative Stress
Low Dose β-carotene Supplementation Diminishes Oxidative Stress in Type 2 Diabetics and Healthy Individuals
Since diabetes has multiple etiologies and oxidative stress one of the proposed mechanisms, the objective is to determine the effect of supplementation with β-carotene to type 2 diabetics and healthy individuals, on iron…
- Conditions
- Diabetes Mellitus, Oxidative Stress, Iron Metabolism Disorders
- Trial name
- NCT01477112
- Testing
- Betacarotene, Controls. No treatment
- Where
- Venezuela
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- Instituto Venezolano de Investigaciones Cientificas
Obesity, Insulin Resistance
Effects of Balanced and Sustainable Diet Application for Insulin Resistance and Inflammation Marker of Obese People
This study evaluates the effect of balanced and sustainable diet application on fat composition, insulin resistance and inflammation marker in obese people.
- Conditions
- Obesity, Insulin Resistance, Inflammation, Blood Glucose, High
- Trial name
- NCT03469869
- Testing
- balanced and sustainable diet
- Where
- Indonesia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance
Effects of Transcutaneous Vagus Nerve Stimulation in Older Adults
The autonomic nervous system consists of two branches, the sympathetic and the parasympathetic, which must work in balance. Its functioning can be measured indirectly by heart rate variability, which is the time between…
- Conditions
- Older Adults Without Any Specific Clinical Condition, Autonomic Nervous System Imbalance, Transcutaneous Vagus Nerve Stimulation
- Trial name
- tVNS_older (NCT07292623)
- Testing
- Active location tVNS
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Universidade da Coruña
Idiopathic Toe Walking, Gait Disorders in Children
Evaluation of Postural Control in Children With Idiopathic Toe Walking
The aim of this study is to evaluate postural control in children with idiopathic toe walking using computerized dynamic posturography (Biodex Balance System), which is reported to be a reliable and valid instrument for detecting…
- Conditions
- Idiopathic Toe Walking, Gait Disorders in Children, Postural Control, Postural Stability
- Trial name
- NCT04200924
- Testing
- Biodex Balance System, Balance Error Scoring System (BESS)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Fluid Retention, Fluid Loss
The Effect of AMP Human Sodium Bicarbonate Lotion on Hydration
The purpose of this research study is to evaluate the effects of a topical sodium bicarbonate lotion on physiological and psychological responses associated with hydration status and fluid balance in humans during passive heat…
- Conditions
- Fluid Retention, Fluid Loss, Sodium Retention, Cognitive Change
- Trial name
- AMPlify (NCT04598386)
- Testing
- PR Lotion - AMP Human Performance
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Asthma
Mass Balance Recovery, Pharmacokinetics and Metabolite Profile and Identification of [14C]AZD7594
AZD7594 is in clinical development for the treatment of asthma. This is a single centre, open-label, single period study in 6 healthy subjects, to determine the mass balance recovery and generate samples to enable metabolite…
- Trial name
- NCT04002427
- Testing
- Intravenous Infusion, Inhaled dose
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Fed
Bioequivalence Study of Bisoprolol Fumarate Tablet 10 mg Under Fed Condition
This is a randomized, open Label, balanced, two-treatment, two-period, two-sequence, single dose, crossover pivotal study. The purpose of this study is to assess the bioequivalence between Test Product and the corresponding…
- Trial name
- NCT01744873
- Testing
- Bisoprolol Fumarate Tablet 10 mg, Bisoprolol
- Where
- India
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- IPCA Laboratories Ltd.
Healthy
Bioequivalence Study of Valsartan 320mg Tablets Under Fed Conditions
The study was an open label, balanced, randomized, two-treatment, two-period, two sequence, single oral dose, crossover, bioequivalence study of two formulations of Valsartan 320 mg under fed conditions.
- Trial name
- NCT02197494
- Testing
- Valsartan
- Where
- India
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ranbaxy Laboratories Limited
Osteoarthritis, Knee
The Treatment of Knee Osteoarthritis With Balanced Buttress Absorbable Spacer
The investigators randomly divided the knee osteoarthritis patients met the inclusive criteria into two groups (study group and control group).
- Trial name
- NCT03060382
- Testing
- balanced buttress absorbable spacer, total knee arthroplasty
- Where
- 2 sites in China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Hebei Medical University Third Hospital
Parkinson Disease, Healthy Adult
Multiple Sessions of Transcranial Direct Current Stimulation in People With Parkinson's Disease
Parkinson's disease (PD) affects approximately 1 million people in the US, with annual health care costs approaching $11 billion. PD results from a loss of dopamine-producing cells in the brain.
- Trial name
- NCT04762823
- Testing
- Cerebellar transcranial direct current stimulation at 4 mA
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Iowa
Patellofemoral Pain Syndrome
Comparison of Foot Posture, Plantar Pressure, and Postural Balance in Patellofemoral Pain Patients and Healthy Subjects
Patellofemoral pain syndrome (PFS) is a musculoskeletal problem characterized by pain felt in the front of the knee or behind the patella, commonly affecting individuals in adolescence or young adulthood, especially those engaged…
- Trial name
- NCT06314360
- Testing
- No intervention.
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Diabetes Mellitus, Type 2
OXEMET™ 1000 mg Coated Tablets (Metformin Hydrochloride) Bioequivalence Study. OXEMET (TM) is a Trademark of the GlaxoSmithKline Group of Companies. GLAFORNIL(TM) is a Trademark of Merck.
This is an open-label, single-center, randomized, 2-way crossover study to evaluate the bioequivalence of OXEMET™ 1000 mg coated tablets, relative to 1000 mg of the reference product administered as two 500 mg tablets, under…
- Trial name
- NCT01842620
- Testing
- Metformin
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Balance Disorders, Fall
Action Observation and Exercise for Balance in Older Adults: A Randomized Trial.
The primary objective is to evaluate the effectiveness of combining action observation with a therapeutic exercise program to improve balance and prevent falls in adults aged ≥65 with low to moderate fall risk.
- Conditions
- Balance Disorders, Fall, Elderly (People Aged 65 or More), Exercise
- Trial name
- AOBAL (NCT07199790)
- Testing
- Action observation videos, Therapeutic exercise
- Where
- Spain
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- University Rovira i Virgili
Parkinson Disease
Comparative Bioavailability Study of Carbidopa/Levodopa Extended-Release Tablets Under Fasting and Fed Conditions
It is an open-label, balanced, randomized, five-treatment, five-period, five-sequence, multiple oral dose, crossover comparative bioavailability study of different strengths of carbidopa/levodopa extended-release tablets with…
- Trial name
- NCT05128175
- Testing
- WD-1603 Carbidopa-Levodopa Extended-Release Tablets
- Where
- India
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Shanghai WD Pharmaceutical Co., Ltd.
Obesity
Circadian Misalignment and Energy Balance
Preliminary findings from the investigators' lab suggest that circadian misalignment, occurring when meals and sleep are mistimed from one another, alters resting state neuronal processing in areas relevant to food reward and…
- Trial name
- CM (NCT03663530)
- Testing
- Meal times
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Columbia University
Patellofemoral Pain Syndrome
Effectiveness of Neuromuscular Exercise in Patellofemoral Pain Syndrome
The aim of the study is to investigate the effects of a neuromuscular exercise program on strength, balance, sleep quality and functionality in individuals with Patellofemoral pain syndrome.
- Trial name
- NCT06407414
- Testing
- control, Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Uskudar University
Vestibular Diseases
Cervical Mobility and Vestibular Rehabilitation
Vertigo, dizziness and imbalance are the main symptoms of vestibular dysfunction. They can lead to physical consequences, such as the reduction of postural control and falls, psychological and / or psychiatric consequences such…
- Trial name
- NCT02622516
- Testing
- Intervention Group (IG), Control Group (CG)
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Viviane de Souza Pinho Costa