Clinical trials: Disorders of Gallbladder
Biliary Disease, Gallstone; Cholecystitis, Acute
Multicentric Point of Care UltraSound by Surgeons Trial
Acute gallbladder pathology and acute diverticulitis are common conditions met in emergency departments and comprise the bulk of admissions throughout general surgical calls.
- Conditions
- Biliary Disease, Gallstone; Cholecystitis, Acute, Diverticulitis, Colonic, Abscess Pelvic
- Trial name
- POCUSS (NCT02682368)
- Testing
- Point of Care Ultrasound by Surgeons (POCUSS), Radiology report, Surgery-Intra-operative findings
- Where
- 5 sites in Ireland, Italy and 2 more
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Connolly Hospital Blanchardstown
Obesity
Study Of The Safety And Pharmacokinetics Of CE-326,597 In Patients With Asymptomatic Gallstones
The study is designed to assess whether repeated dosing with CE-326,597 will cause patients with asymptomatic gallstones (as detected on screening abdominal ultrasound) to become symptomatic.
- Trial name
- NCT00576589
- Testing
- CE-326,597
- Where
- 12 sites in United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Pfizer
Gallbladder Cancer
Poorly Differentiated Adenocarcinoma With Signet Ring Cells of the Gallbladder Producing a High Level of Alpha-fetoprotein: a Case Report
Alpha-fetoprotein (AFP) can become elevated in hepatocellular carcinoma (HCC), yolk sac tumors and other malignant tumors of various organs.
- Trial name
- NCT05559229
- Testing
- laparoscopic whole-layer cholecystectomy
- Where
- Japan
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- junya mita
Cholecystolithiasis
Closed-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy
Laparoscopic Cholecystectomy applied to Artificial pneumoperitoneum and the extent of Surgical stimulation cause the wave of hemodynamics increase vigorously, which make it difficult to judge the depth of anesthesia according to…
- Trial name
- CLTCI (NCT02114437)
- Testing
- Closed-loop TCI, Opened-loop TCI
- Where
- China
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Guangzhou General Hospital of Guangzhou Military Command
Cholecystolithiasis
A Survey of Public Attitudes Towards Gallbladder-preserving Lithotomy and Its Influencing Factors
This study aims to understand public/patient attitudes toward gallbladder preservation surgery by means of questionnaires, and hopes to achieve the following objectives: 1.
- Trial name
- NCT07854379
- Where
- China
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Changzhou No.2 People's Hospital
Cholecystectomy, Laparoscopic, Cholelithiasis
Improvised Endobag vs Direct Gallbladder Extraction in Laparoscopic Cholecystectomy
Eligigble patients will be enrolled after obtaining informed consent. Basic information such as age, gender, body weight, smoking and alcohol history, number of gallstones, and gallbladder characteristics will be recorded.
- Trial name
- NCT07823803
- Testing
- Endobag
- Where
- Pakistan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Rawal Institute of Health Sciences Islamabad
Cholecystitis
SPY Fluorescence Imaging Systems and Indocyanine Green to Determine the Percentage of Successful Critical Anatomy Recognition in Laparoscopic Cholecystectomy Surgeries.
This is a prospective single arm, single center study estimating percentage of successful critical anatomy recognition in laparoscopic cholecystectomy surgeries using SPY fluorescence imaging and ICG, with each surgery also…
- Trial name
- NCT05006950
- Testing
- Stryker1688 Fluorescence imaging system
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Stryker Endoscopy
Cholelithiasis, Cholecystitis
Efficacy of Proficiency-based Versus Free Laparoscopic Training in Cholecystectomy on a Virtual Reality Simulator
Virtual reality devices are widely accepted tools to familiarize surgical novices with the principles of laparoscopy. Free Virtual reality training will be tested against basic training and efficacy assessed in a randomized…
- Conditions
- Cholelithiasis, Cholecystitis, Cholecystolithiasis
- Trial name
- NCT01615549
- Testing
- Laparsocopic cholecystectomy
- Where
- 2 sites in Switzerland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Metastatic Cancer, Foregut Carcinoid Tumor
Study Comparing Standard of Care Chemotherapy With/ Without Sequential Cytoreductive Surgery for Patients With Metastatic Foregut Cancer and Undetectable Circulating Tumor-Deoxyribose Nucleic Acid Levels
This study is designed for participants who have cancer of the upper gastrointestinal (GI) tract such as cancer of the esophagus, stomach, duodenum (the initial portion of your small intestine), pancreas, bile duct…
- Conditions
- Metastatic Cancer, Foregut Carcinoid Tumor, Gastric Adenocarcinoma, Gallbladder Adenocarcinoma
- Trial name
- NCT04931420
- Testing
- Standard of Care Chemotherapy, Video-Assisted Thoracic Surgery (VATS), Lobectomy
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Chicago
Cholecystitis, Cholelithiasis
Feasibility and Utility of Artificial Intelligence (AI) / Machine Learning (ML) - Driven Advanced Intraoperative Visualization and Identification of Critical Anatomic Structures and Procedural Phases in Laparoscopic Cholecystectomy
The goal of this study is to evaluate the utility and efficacy of an artificial intelligence (AI) model at identifying structures and phases of surgery compared to traditional white light assessment by trained surgeons.
- Conditions
- Cholecystitis, Cholelithiasis, Biliary Dyskinesia
- Trial name
- NCT05775133
- Testing
- ICG
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Activ Surgical
Gallbladder Diseases
Emergency Ultrasound of the Gallbladder
The purpose of this study is to determine whether fasting for 8 hours prior to ultrasonography for cholelithiasis (gallbladder pain) is needed.
- Trial name
- NCT00388830
- Testing
- Ultrasound
- Where
- United States
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Endoscopic Retrograde Cholangiopancreatography , Gallstone
Nonradiation-to-endoscopist Endoscopic Retrograde Cholangiopancreatography in Patients With Complexity Level I/II
Radiation exposure may put endoscopists at risk when performing endoscopic retrograde cholangiopancreatography. Although non-radiation endoscopic retrograde cholangiopancreatography was reported in pregnant women in previous…
- Trial name
- NCT02697149
- Testing
- nonradiation-to-endoscopist endoscopic retrograde cholangiopancreatography, standard endoscopic retrograde cholangiopancreatography
- Where
- 2 sites in China
- Volunteers
- 219 people, healthy volunteers welcome
- Sponsor
- Air Force Military Medical University, China
Laparoscopic Cholecystectomy, Post Operative Analgesia
Postoperative Pain After Instillation Of Bupivacaine During Laparoscopic Cholecystectomy
This study aims to compare the level of postoperative pain experienced by patients undergoing laparoscopic cholecystectomy with and without the use of intraperitoneal bupivacaine.
- Conditions
- Laparoscopic Cholecystectomy, Post Operative Analgesia, Bupivacaine
- Trial name
- BUPA-LC (NCT07098429)
- Testing
- Bupivacain (Postoperative), Normal (0.9%) saline
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Recep Tayyip Erdogan Hospital Pakistan - Muzaffargarh
Cholelithiasis
Comparison of Postoperative Pain After Gallbladder Retrieval From Umbilical and Epigastric Ports.
To know the association of postoperative pain after gallbladder removal from umbilical port site versus epigastric portsite, after four ports laparoscopic cholecystectomy,and the epigastric port site was found to be friendly for…
- Trial name
- NCT04208568
- Testing
- Laparoscopic cholecystectomy
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Baqai Medical University
Ascites, Blunt Abdominal Trauma
Telesonography Adaptation and Use to Improve the Standard of Patient Care Within a Dominican Community
The role of teleradiology has far reaching implications for the health of remote and underserved populations. The ability to coordinate radiographic evaluation and diagnosis from a distance has the potential to raise the standard…
- Conditions
- Ascites, Blunt Abdominal Trauma, Cholelithiasis, Cholecystitis
- Trial name
- NCT00591968
- Testing
- SonoSite Titan portable ultrasound coupled with email telediagnosis
- Where
- Dominican Republic
- Volunteers
- 106 people, healthy volunteers welcome
- Sponsor
- Edward Via Virginia College of Osteopathic Medicine
Gall Stones (& [Calculus - Gall Bladder]), Surgery
Major Surgery as a Risk of Gall Stone Disease?
Gall stone disease is one of the most common diseases occurring in the world as well as in our country, Nepal. This disease is problematic to a lot of patients and poses a huge economic burden to the country.
- Trial name
- NCT04675190
- Testing
- Major abdominal Surgery
- Where
- 3 sites in Nepal
- Volunteers
- 755 people, healthy volunteers welcome
- Sponsor
- Nepal Medical College and Teaching Hospital
Cholecystitis, Acute
The Role of Ultrasound in Cholecystitis
The aim of this study is: 1. To describe the natural course of acute cholecystitis, by performing repeated ultrasound examinations from day of admission to hospital until day of surgery or discharge. 2.
- Trial name
- NCT03470220
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Disorders of Gallbladder, Biliary Tract and Pancrease
Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine.
The purpose of this study is to compare efficacy and safety of combination of propofol and midazolam with meperidine versus midazolam and meperidine for ambulatory ERCP
- Trial name
- ERCP (NCT01709422)
- Testing
- Propofol, Midazolam, Meperidine
- Where
- Thailand
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Prince of Songkla University
Hemodynamics Instability, Post Operative Pain
Evaluating Perioperative Outcomes: Dexmedetomidine vs Lignocaine in Laparoscopic Chlolecystectomy
Nowadays laparoscopic surgery is the first choice for many surgeries. Such surgeries have revolutionized the surgical practice and has markedly reduced the incidence of intraoperative and postoperative complications.
- Conditions
- Hemodynamics Instability, Post Operative Pain, Gastrointestinal Dysfunction, Cholecystitis
- Trial name
- NCT06740903
- Testing
- inj. dexmedetomidine infusion @ 0.2-0.4 μg/kg/h, inj. lignocaine infusion @1-2 mg/kg/h
- Where
- Pakistan
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Sahiwal medical college sahiwal
Gallstone
Effectiveness of Guided Imagery Meditation in Patients With Laparoscopic Gallstone Surgery
Guided image meditation has been shown to alter the functional circuits of the brain to alleviate pain by mediating breathing and thoughts.
- Trial name
- NCT04390828
- Testing
- Guided Imagery Meditation
- Where
- 2 sites in Taiwan
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University Hospital