Clinical trials: Disruptive Mood Dysregulation Disorder
Attention-Deficit and Hyperactivity Disorder, Anxiety
Correlating Real and Virtual World Behavioral Fluctuations in Adolescence
The present study will explore a new approach to ongoing evaluation and monitoring of fluctuations in personality traits via commercial video games.
- Conditions
- Attention-Deficit and Hyperactivity Disorder, Anxiety, Disruptive Mood Dysregulation Disorder, Depression
- Trial name
- NCT02281825
- Where
- Israel
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shalvata Mental Health Center
Irritability, Disruptive Mood Dysregulation Disorder
Psychotherapy for Irritability in Youth: Comparing Active Treatment to Nonactive Psychoeducation Supportive Psychotherapy
Background: Irritability is defined as proneness to anger that may impair a person's ability to function. It is a common reason for why some children need mental health care.
- Conditions
- Irritability, Disruptive Mood Dysregulation Disorder, Oppositional Defiant Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT07640802
- Testing
- Psychotherapy
- Where
- United States
- Volunteers
- 410 people
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction
Optimizing Research With Diverse Families - Feasibility and Acceptability Study (FAST)
Evaluate feasibility and acceptability of recruiting Black and Hispanic families for an open label clinical trial of multinutrients while collecting real-time parent-reported child behavior data and collecting at-home…
- Conditions
- Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
- Trial name
- FAST (NCT06133231)
- Testing
- Multinutrients; a 36-ingredient blend of vitamins, minerals, amino acids, and antioxidants
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Oregon Health and Science University
Irritability
Attention Bias Modification, Attention Control and Psychoeducation for Irritability in Children and Adolescents
The aim of this project is to evaluate the efficacy of an attention bias modification training if compared to an attention control and psychoeducation to reduce the symptoms of irritability among children with high levels of…
- Trial name
- NCT03238118
- Testing
- Attention bias modification training, Attention Control Training, Psychoeducation
- Where
- Brazil
- Volunteers
- 140 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Emotional Dysregulation
Patients Suffering From Emotional Dysregulation
Emotional dysregulation (ED) is a common syndrome in psychiatric disorders. It is characterized by intense emotions, easily triggered, and with significant psychological impact: explosions of anger, irritability, impulsivity…
- Trial name
- Dys-Emotion (NCT06616337)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Strasbourg, France
Disruptive Mood Dysregulation Disorder
Adapting DBT for Children With DMDD: Pilot RCT
This study examines feasibility and preliminary efficacy of Dialectical Behavior Therapy adapted to children (DBT-C). DBT-C as compared to treatment-as-usual (TAU) is hypothesized to have lower drop-out rate, and higher treatment…
- Trial name
- NCT01862549
- Testing
- Dialectical Behavior Therapy for children, Treatment as Usual
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Weill Medical College of Cornell University
Disruptive Mood Dysregulation Disorder, Prognosis Factors
Evolution of DMDD Children and Adolescent
Little is known about the natural course and prognosis factors of inpatients and outpatients with Disruptive Mood Dysregulation Disorder (DMDD).
- Conditions
- Disruptive Mood Dysregulation Disorder, Prognosis Factors, Suicidal Behaviors, Actigraphy
- Trial name
- ACTIHUMEURp3 (NCT04820946)
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire, Amiens
Disruptive Mood Dysregulation Disorder
Aripiprazole Added on for DMDD in Youths With ADHD
Objectives: 1. To investigate the effectiveness of adjuvant with aripiprazole to methylphenidate for disruptive mood dysregulation disorder (DMDD) in youths with attention-deficit/hyperactivity disorder (ADHD) 2.
- Trial name
- AAOFDIYWA (NCT03358277)
- Testing
- MPH + APZ
- Volunteers
- 58 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Irritable Mood, ADHD
Irritability in Children With ADHD and Emotion Dysregulation
Objective: Emotion dysregulation is common among children with ADHD and associated with a broad range of adult psychopathology, which is similar to the longitudinal outcomes of childhood irritability.
- Trial name
- NCT05974241
- Testing
- Methylphenidate, aripiprazole, and combination
- Where
- Taiwan
- Volunteers
- 36 people
- Sponsor
- Tri-Service General Hospital (TSGH)
Pregnancy, Mother
A Feasibility Study of AMOR; ADHD, Mothers Online Resources
The primary aim of this study is to investigate the feasibility of the program AMOR for pregnant women and new mothers with Attention Deficit Hyperactivity Disorder (ADHD), by examining adherence, credibility, treatment…
- Conditions
- Pregnancy, Mother, Women, Attention Deficit Disorder With Hyperactivity
- Trial name
- AMOR (NCT06679010)
- Testing
- Online group counseling
- Where
- Denmark
- Volunteers
- 31 people
- Sponsor
- University of Southern Denmark
Mood Disorder, Disruptive Behavior Disorders
Oxytocin on Irritability/Emotional Dysregulation of Disruptive Behavior and Mood Disorders
Irritability and emotional dysregulation are recognized as serious aspects of psychopathology seen in in pediatric psychiatric patients.
- Trial name
- NCT02824627
- Testing
- Oxytocin
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- University of Nebraska
Emotion Regulation, Mood Disorders
Neurostimulation Versus Therapy for Problems With Emotions
The primary goal of this clinical trial is to evaluate the unique neural and behavioral effects of a one-session training combining emotion regulation skills training, with excitatory repetitive transcranial magnetic stimulation…
- Conditions
- Emotion Regulation, Mood Disorders, Stress Disorder, Anxiety Disorders
- Trial name
- NCT05712057
- Testing
- Repetitive Transcranial Magnetic Stimulation (rTMS), electrical scalp stimulation, Cognitive Restructuring
- Where
- United States
- Volunteers
- 240 people
- Sponsor
- Duke University
Mood Disorder, Mental Disorder Diagnosed in Childhood
A Controlled Trial of Serotonin Reuptake Inhibitors Added to Stimulant Medication in Youth With Severe Mood Dysregulation
Severe mood dysregulation (SMD) is a very common syndrome in children. Its symptoms include very severe irritability, including persistent anger and frequent outbursts, as well as distractibility, hyperactivity, and other…
- Conditions
- Mood Disorder, Mental Disorder Diagnosed in Childhood, Attention Deficit and Disruptive Behavior Disorder, Attention Deficit Hyperactivity Disorder
- Trial name
- NCT00794040
- Testing
- Add-on citalopram following optimized methylphenidate
- Where
- United States
- Volunteers
- 103 people
- Sponsor
- National Institute of Mental Health (NIMH)
Severe Mood Dysregulation
Interpersonal Psychotherapy for Youth With Severe Mood Dysregulation
The purpose of this study is to determine the feasibility and acceptability of utilizing an adapted form (i.e. IPT-MBD) of a psychosocial intervention, Interpersonal Psychotherapy for Depressed Adolescents, for youth with severe…
- Trial name
- NCT01962623
- Testing
- IPT-MBD
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- Johns Hopkins University
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Characterization and Brain Mechanisms of Frustration in Youth With Severe Irritability or Attention Deficit Hyperactivity Disorder (ADHD)
Background: Irritability is an elevated proneness to anger. Children with irritability have difficulty tolerating frustration. They get angry and have temper outbursts more easily than their others their age.
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Normal Physiology
- Trial name
- NCT05357495
- Testing
- Affective Posner fMRI frustration induction task
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- National Institute of Mental Health (NIMH)
Disruptive Behavior Disorder, Childhood Onset, Attention Deficit Hyperactivity Disorder
Enhanced Support for Behavioral Barriers to Learning: An Evaluation of the SCHOOL STARS Program
This small pilot study will enroll children ages 5-12 years of age with disruptive behavior problems at school. These children and their families will be offered an enhanced model of primary care, which includes pre-visit record…
- Conditions
- Disruptive Behavior Disorder, Childhood Onset, Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder in Children, Disruptive Mood Dysregulation Disorder
- Trial name
- NCT03669289
- Testing
- enhanced model of primary care
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Mood Disorder
Studies of Brain Function and Course of Illness in Pediatric Bipolar Disorder
This study seeks to learn more about the symptoms of severe mood dysregulation in children and adolescents ages 7-17. Children and adolescents with severe mood dysregulation (SMD) display chronic anger, sadness, or irritability…
- Trial name
- NCT00025935
- Testing
- Lithium
- Where
- United States
- Volunteers
- 2,350 people
- Sponsor
- National Institute of Mental Health (NIMH)
Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction
Focus Groups in Ethnically and Racially Diverse Families
Focus groups to identify treatment needs and barriers to participation in the planned multinutrient study among racially and ethnically diverse (Black and Hispanic) communities.
- Conditions
- Attention Deficit/Hyperactivity Disorder, Emotional Dysfunction, Irritable Mood
- Trial name
- NCT05930886
- Testing
- Focus Group
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Oregon Health and Science University
Attention Deficit Hyperactivity Disorder, Disruptive Mood Dysregulation Disorder
Children With ADHD and Emotional Dysregulation
Studies have shown that children with Attention Deficit Hyperactivity Disorder (ADHD) and emotional dysregulation are characterized by high severity of ADHD, comorbid behavior disorders and increased risk of chronic difficulties.
- Trial name
- MOODY (NCT03944083)
- Testing
- Treatment as usual for ADHD
- Where
- Norway
- Volunteers
- 200 people
- Sponsor
- Oslo University Hospital
Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder
Symptoms and Mechanisms of Child Psychiatric Disorders
In this study the investigators will examine psychiatric symptoms, central neurocognitive functions, parental stress and attachment styles, and biological factors that can give new knowledge about some of the mechanisms present…
- Conditions
- Disruptive Mood Dysregulation Disorder, Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Severe Irritability
- Trial name
- NCT05049356
- Where
- 2 sites in Norway
- Volunteers
- 218 people
- Sponsor
- Oslo University Hospital