Clinical trials: Dissecting Aneurysm
Ischemic Stroke
Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection
Pilot Study of Aspirin Versus Warfarin for Cervicocephalic Arterial Dissection.
- Trial name
- NCT00265408
- Testing
- aspirin, warfarin
- Where
- United States
- Sponsor
- University of California, San Diego
Dissecting Aneurysm of Cerebral Artery
Metformin in Patients With Unruptured Vertebrobasilar Dissecting Aneurysms (METTLE)
Vertebrobasilar dissecting aneurysms (VBDAs) are one of the most important causes of stroke in young and middle-aged people, and the natural history of VBDAs is complex and varied, often leading to high rates of disability and…
- Trial name
- METTLE (NCT06405971)
- Testing
- Metformin
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Ming Lv
Stroke (CVA) or TIA, Headache, Migraine
Onabotulinum Toxin A (Botox) for the Treatment of Persistent Post-Stroke and Vascular Headache
Post stroke headache occurs in approximately 10-23% of all stroke patients. Its onset is shortly after experiencing a stroke, or stroke like event, and persists for at least three months.
- Conditions
- Stroke (CVA) or TIA, Headache, Migraine, Botulinum Toxins, Type A, Cerebral Venous Sinus Thrombosis
- Trial name
- NCT04580238
- Testing
- Botox 200 UNT Injection, Non Botox based Standard of Care Treatments for Headache/Migraine
- Where
- Canada
- Sponsor
- University of Alberta
Retinal Detachment, Achilles Tendon
A Study of Fluoroquinolones Exposure and Collagen-Related Serious Adverse Events
The purpose of this study is to evaluate whether there is an increased risk of achilles tendon rupture (ATR), retinal detachment (RD) or aortic aneurysm and dissection (AAD) following exposure to fluoroquinolone (FQ) or other…
- Conditions
- Retinal Detachment, Achilles Tendon, Aneurysm, Dissecting
- Trial name
- NCT03479736
- Testing
- Oral Fluoroquinolones (FQ), Other Antibiotics, Febrile Illness Not Treated with Antibiotics Will be Analyzed as an Exposure
- Where
- United States
- Volunteers
- 117,911 people
- Sponsor
- Janssen Research & Development, LLC
Spontaneous Coronary Artery Dissection, SCAD
Genetic Investigations in Spontaneous Coronary Artery Dissection (SCAD)
The purpose of the research is to identify mutations (defects in the genetic blueprint) that cause spontaneous coronary artery dissection (SCAD), in other words, spontaneous tears in blood vessels that supply the heart.
- Trial name
- NCT01427179
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Spontaneous Coronary Artery Dissection
Randomized Study of Beta-Blockers and Antiplatelets in Patients With Spontaneous Coronary Artery Dissection
Spontaneous coronary artery dissection (SCAD) is a cause of acute coronary syndrome (ACS). Most patients are treated with beta-blockers (BB) and antiplatelet drugs (AP) on empiric basis.
- Trial name
- BA-SCAD (NCT04850417)
- Testing
- Beta blocker, aspirin, clopidogrel
- Volunteers
- 600 people
- Sponsor
- Spanish Society of Cardiology
Dissecting Aneurysm of Cerebral Artery
Dynamic Contrast-Enhanced Magnetic Resonance Imaging Analysis for Prognosis of Intracranial Dissecting Aneurysm With Intramural Hematoma After Endovascular Treatment
This study will evaluate the feasibility to predict the prognosis of IDA with IMH by DCE-MRI and provide theoretical basis for the prognosis and intervention of the disease.
- Trial name
- DEMAT (NCT03940859)
- Testing
- intracranial stent, flow diverter and coils
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Beijing Neurosurgical Institute
Vertebral Artery Dissection, Cerebrovascular Accident
Vertebral Artery and Cerebral Hemodynamics After Various Head Positions & Manipulation in Patients With Neck Pain
The Investigators are performing a study to determine, in patients with chronic/recurrent neck pain, the cerebrovascular hemodynamic consequences of cervical spine movements, including manipulation, in vivo using fMRI technology…
- Conditions
- Vertebral Artery Dissection, Cerebrovascular Accident, Stroke
- Trial name
- NCT02667821
- Testing
- Head positions and spinal manipulation
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Canadian Memorial Chiropractic College
Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection
Defining the Basis of Fibromuscular Dysplasia (FMD)
The purpose of this study has evolved and expanded since its inception. Originally the intent was to establish the functional, molecular and genetic profile of fibroblasts from Fibromuscular Dysplasia (FMD) patients as compared…
- Conditions
- Fibromuscular Dysplasia, Spontaneous Coronary Artery Dissection, Cervical Artery Dissection
- Trial name
- DEFINE (NCT01967511)
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Aortic Dissection, Aneurysm, Dissecting
The Branch-based Intraoperative Stent System in the Treatment of Stanford A Aortic Dissection（BROAD）
The purpose of the study was to evaluate the safety and efficacy of a branched type intraoperative stent system for the treatment of Stanford type A aortic dissection
- Conditions
- Aortic Dissection, Aneurysm, Dissecting, Aneurysm, Vascular Diseases
- Trial name
- BROAD (NCT05659641)
- Testing
- PerMed Stent Graft System In Surgical Operation, Endovastec CRONUS® Intraoperative stent system
- Where
- 18 sites in China
- Volunteers
- 259 people
- Sponsor
- Permed Biomedical Engineering Co., Ltd
Spontaneous Coronary Artery Dissection
Spontaneous Coronary Artery Dissection (SCAD) Avatar Study
The purpose of this study is to evaluate patient satisfaction, comfort, and trust in interacting with an avatar compared with speaking to a human clinician during a pre clinical visit.
- Trial name
- NCT07497633
- Testing
- Video Avatar Interview, Voice-Only Avatar Interview, Human Interview
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- Mayo Clinic
Cardiac Rehabilitation Program Following the Management of ACS in Patients Presenting With SCAD
Modalities And Safety Of Cardiac Rehabilitation In A Population Managed For Spontaneous Hematoma Or Coronary Disruption
Spontaneous Coronary Artery Dissection (SCAD) is a rare and often misdiagnosed cause of Acute Coronary Syndrome (ACS) affecting predominantly young women without cardiovascular risk factors.
- Trial name
- READAPT-DISCO (NCT05744947)
- Testing
- Data collection
- Where
- 29 sites in France
- Volunteers
- 90 people
- Sponsor
- University Hospital, Bordeaux
Spontaneous Coronary Artery Dissection
Angiographic and Psychosocial Evaluation of Peripartum vs. Non: SCAD
This multi-site international clinical research project is a collaboration between investigators from multiple institutions in the USA, Canada, and Europe.
- Trial name
- SCAD (NCT03390998)
- Where
- United States
- Volunteers
- 241 people
- Sponsor
- Katharine Sears Edwards
Intracranial Aneurysm
Endovascular Treatment of Wide Neck Intracranial Aneurysms With the LEO + Stent : The LEO + II Cohort Study
This is a prospective, multicenter, single-arm observational study to evaluate the efficacy and the morbi-mortality of LEO + in patients with wide neck intracranial aneurysms (fusiform, saccular or dissecting), ruptured or not…
- Trial name
- NCT03504436
- Testing
- LEO +
- Volunteers
- 176 people
- Sponsor
- Balt Extrusion
Spontaneous Isolated Superior Mesenteric Artery Dissection
Comparison of Conservative and Endovascular Treatment for Spontaneously Isolated Superior Mesenteric Artery Dissection
Spontaneous isolated superior mesenteric artery dissection(SISMAD) is an increasingly diagnosed disease. However, prospective, multicenter studies that can provide evidence to support clinical decisions are very limited.
- Trial name
- NCT05342233
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xiangya Hospital of Central South University
Spontaneous Coronary Artery Dissection
Canadian SCAD Study
SCAD (Spontaneous coronary artery dissection - tear in the arterial wall that is not related to trauma) is an under-diagnosed and poorly understood condition that mostly affects young women without common cardiovascular risk…
- Trial name
- NCT02188069
- Where
- 20 sites in United States, Canada
- Volunteers
- 750 people
- Sponsor
- Cardiology Research UBC
Vascular Diseases
Superior Mesenteric Artery Dissection
This study investigate CT images of patients with spontaneous isolated superior mesenteric artery dissection (SISMAD). The investigators also further analyze the CT morphological differences between different options, aiming to…
- Trial name
- NCT03669380
- Where
- China
- Volunteers
- 57 people
- Sponsor
- Tongji Hospital
Vascular Disease, Dissection
Long-term Characterization of GORE® TAG® Conformable Thoracic Stent Graft With ACTIVE CONTROL System Performance
An observational, prospective multi-regional post-market registry collecting mid- and long-term data to assess outcomes through ten years of follow-up for subjects treated with GORE® TAG® Conformable Thoracic Stent Graft with…
- Conditions
- Vascular Disease, Dissection, Dissection Aortic Aneurysm, Dissection of Aorta
- Trial name
- TGR 23-02TA (NCT06658730)
- Testing
- Endovascular
- Where
- 37 sites in United States, Denmark and 8 more
- Volunteers
- 1,500 people
- Sponsor
- W.L.Gore & Associates
Cervical Artery Dissection, Stroke
Looking For Genetic and Environmental Risk Factors and Therapeutic Aspects in Cervical Artery Dissections
The main purpose of this study is to look for genetic and environmental risk factors of cervical artery dissections, a major cause of ischemic stroke in young adults, in a large multicenter case-control trial
- Conditions
- Cervical Artery Dissection, Stroke, Brain Infarction
- Trial name
- CADISP (NCT00657969)
- Where
- 24 sites in Argentina, Belgium and 7 more
- Volunteers
- 4,169 people
- Sponsor
- Cervical Artery Dissections and Ischemic Stroke Patients - Consortium
Laparoscopic Cholecystectomy Surgery
Cystic Artery Dissection With Dorsal Infundibular Approach Versus Critical View of Safety
We evaluated the efficacy of combining cystic artery dissection with a dorsal infundibular approach in comparison to the critical view of safety.
- Trial name
- NCT07507292
- Testing
- critical view of saftey, cystic artery dissection with dorsal infundibular dissection
- Where
- Egypt
- Volunteers
- 300 people
- Sponsor
- Zagazig University