Clinical trials: Dissociative Disorder
Functional Neurological Disorders
The Pathophysiology of Functional Neurological Disorders
Functional disorders, also called psychogenic or psychosomatic are very common, disabling and their costs to society are immense.
- Trial name
- NCT02905877
- Testing
- Behavioural study
- Where
- United Kingdom
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- University College, London
Psychogenic Movement Disorders, Non-epileptic Seizures
Psychiatric Correlates of Psychogenic Movement Disorder and Non-Epileptic Seizure
This study will explore how the mind and the brain work to cause movement symptoms or seizures in people who do not have a recognized neurological or medical disorder.
- Trial name
- NCT00255411
- Where
- United States
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Hypnosis
Interest of Catalepsy in the Hypnotic Trance
Catalepsy seems to facilitate hypnotic induction and deepen hypnotic trance, although no work confirms the usefulness of this technique which is in common use in hypnosis.
- Trial name
- CATALHYPNOANI (NCT05306262)
- Testing
- Hypnosis session, Catalepsy
- Where
- France
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- CMC Ambroise Paré
Post-Traumatic Stress Disorders, Anxiety
fMRI in Posttraumatic Stress Disorder (PTSD) During Working Memory Updating
Neuropsychological studies investigating trauma-exposed and posttraumatic stress disorder (PTSD) subjects have generally underlined the significantly poorer performance of tasks that require attention, concentration, and verbal…
- Conditions
- Post-Traumatic Stress Disorders, Anxiety, Amnesia, Dissociative
- Trial name
- METRAPI (NCT00288314)
- Testing
- Magnetic Resonance Imaging, Functional
- Where
- France
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Functional Neurological Disorder
The Role of Oxytocin and Interoception in Functional Neurological Disorder
The main goal of this project is to better understand the role of oxytocin and Interoception in FND. More specifically oxytocin's association with precision weighing, prediction errors and priors in the interoceptive domains will…
- Trial name
- NCT06084325
- Testing
- Respiration resistance sensitivity task (RRST), Heartbeat Tracking (HBT), Heartbeat evoked potential (HEP)
- Where
- 2 sites in Switzerland
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Complex Posttraumatic Stress Disorder (cPTSD), Dissociative Disorder Not Otherwise Specified (DDNOS)
Emotional and Cognitive Self-regulation, an EEG Study
The main goal of the proposed project is to assess treatment-induced changes of electrophysiological and psychophysiological correlates of the capacity to regulate emotion, executive functions, and clinical measures in…
- Conditions
- Complex Posttraumatic Stress Disorder (cPTSD), Dissociative Disorder Not Otherwise Specified (DDNOS), Dissociative Identity Disorder (DID)
- Trial name
- ECSR (NCT02459340)
- Testing
- therapeutic treatment (inpatient and outpatient setting)
- Where
- Switzerland
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yolanda Schlumpf, PhD
Amblyopia
A Comparative Study Between Dissociative Treatment and Binocular Interactive Treatment in Amblyopia
Amblyopia is a unilateral or, infrequently, a bilateral reduction of best corrected visual acuity which cannot be attributed to coexisting eye or visual pathway disease.
- Trial name
- NCT03255707
- Testing
- eye patch, dichoptic treatment
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Functional Neurological Disorder, Motor Symptoms
Investigating the Neurophysiology of the Motor System and the Feasibility of Vagus Nerve Stimulation in Functional Neurological Disorder (FND)
This clinical study will test if adding a non-invasive stimulation of the vagus nerve through the ear during physiotherapy brings an improvement to FND (Functional Neurological Disorder) patients with motor symptoms.
- Trial name
- TMS-VNS (NCT07710677)
- Testing
- Vagial Nerve Stimulation (VNS) active stimulation
- Where
- Switzerland
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Fribourg
Schizophrenia, Autistic Disorder
Exploration of the Social Cognition in Adolescents With a Dissociative Disorder or Autism Spectrum
The schizophrenic disorders and pervasive developmental disorders are neurodevelopmental disorders distinct origin who share common challenges to engage and maintain social relationships and mutual disturbances of affective…
- Trial name
- NCT01805128
- Testing
- Facial recognition of emotions, understanding metaphors, Attribution of intentionality to others in social situations depending on the type of situation
- Where
- 3 sites in France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Parkinson Disease, Movement Disorder, Functional
The Effects of fNIRS-based Neurofeedback Training on Balance and Gait in Parkinson's Disease
A cross-sectional study (part 1) aims to investigate the influence of fatigue on the MI ability in PD compared to healthy controls.
- Trial name
- NCT05800470
- Testing
- fNIRS-based neurofeedback with motor imagery, Kinesthetic motor imagery, Motor training
- Where
- Taiwan
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- National Yang Ming Chiao Tung University
Depressive Disorder, Treatment-Resistant, Stress Disorders, Post-Traumatic
Ketamine Infusions for PTSD and Treatment-Resistant Depression
The relationship between depression and trauma is well established. Co-occuring depression and post-traumatic stress disorder (PTSD) are associated with more severe symptoms and lower levels of functioning.
- Trial name
- NCT02577250
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Minneapolis Veterans Affairs Medical Center
Seizure Disorder, Seizure Disorder, Post Traumatic
Neuroimaging Biomarker for Seizures
This multi-site study will examine patients with epilepsy (ES) following head injury [i.e., posttraumatic epilepsy (PTE)] and posttraumatic psychogenic Non-epileptic seizures (PNES) and will compare them to patients with…
- Conditions
- Seizure Disorder, Seizure Disorder, Post Traumatic, Traumatic Brain Injury, Non-Epileptic Seizure
- Trial name
- NIBMSZS (NCT03441867)
- Testing
- Cognitive Behavioral Therapy for Seizures, Standard Medical Care
- Where
- 3 sites in United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Providence VA Medical Center
Posttraumatic Stress Disorders, Dissociative Identity Disorder
Evaluating the Neurobiological Basis of Traumatic Dissociation in Women With Histories of Abuse and Neglect
This study aims to evaluate the neurobiological basis of traumatic dissociation in a cross-diagnostic sample of women who have histories of childhood abuse and neglect.
- Trial name
- NCT02757339
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Depression, Anxiety, Post-traumatic Stress Symptoms
Predictors and Process Moderators of EMDR Therapy for Depressive Symptoms
The goal of this clinical trial is to evaluate which factors influence the effectiveness of Eye Movement Desensitization and Reprocessing (EMDR) therapy for depressive symptoms in real-world settings in Italy.
- Conditions
- Depression, Anxiety, Post-traumatic Stress Symptoms, Dissociation, Psychotherapy Research and Outcome Measures
- Trial name
- PROCESS-EMDR (NCT07033741)
- Testing
- EMDR
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Functional Movement Disorder
Passive Thoughts in Functional Movement Disorders
Passive thoughts also known as mind-wandering are the thoughts that are not produced from the current task. When we aren't focused on a task that needs our full attention, our minds tend to drift from one thought to another.
- Trial name
- NCT06439017
- Testing
- Questionaire
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Western University, Canada
Functional Neurological Disorder
Feasibility of Remotely Measured Activity Behavior for Individuals With Functional Neurologic Disorder
This study evaluates whether remotely measured daily activity behavior, captured through a thigh-worn accelerometer, can serve as a reliable and ecologically valid indicator of symptom impact in individuals with Functional…
- Trial name
- NCT07478666
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Functional Movement Disorders
Brain Activity in People With Functional Movement Disorders
This study will use functional MRI (fMRI, a technique that shows what areas of the brain are active when performing different mental tasks), to examine how the brain in people with functional movement disorders (FMD) may differ…
- Trial name
- NCT00448084
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Functional Neurological Symptom Disorder, Paralysis
Exploring Functional Paralysis with Advanced Magnetic Resonance Modalities
In functional neurological disorder (FND), neurological symptoms are present, such as paralysis, weakness and disturbed sensation of limbs, although clinically no abnormalities can be found.
- Conditions
- Functional Neurological Symptom Disorder, Paralysis, Conversion Disorder with Weakness/Paralysis
- Trial name
- NCT05139732
- Testing
- Magnetic Resonance Imaging (MRI)
- Where
- Switzerland
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Swiss Paraplegic Research, Nottwil
Epilepsy, Functional Neurological Disorder
EXercise-induced PhysioLogical Adaptations In Neurological Disorders
The goal of this study is to investigate how a one-time exercise session influences different parameters of brain function in people with neurological diseases compared to healthy volunteers.
- Conditions
- Epilepsy, Functional Neurological Disorder, Mild Cognitive Impairment, Dementia
- Trial name
- EXPLAIN (NCT07883720)
- Testing
- Acute Exercise
- Where
- United States
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital