Clinical trials: Distal Tibia Fracture
Distal Humerus Fracture, Distal Femur Fracture
3D-printed Bone Models in Addition to CT Imaging for Intra-articular Fracture Repair
The purpose of this study is to compare the effectiveness of 3D-printed bone models in addition to CT imaging versus CT imaging alone on surgical quality and operation time for patients undergoing surgical repair of…
- Conditions
- Distal Humerus Fracture, Distal Femur Fracture, Distal Tibia Fracture, Proximal Humeral Fracture
- Trial name
- SPRINT (NCT04748016)
- Testing
- 3D printed (3DP) bone models + CT imaging, CT imaging
- Where
- Hong Kong
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Humerus Fracture, Femur Fracture
Evaluation of Handling and Possible Complications Related to the Newly Developed Angular Stable Locking System (ASLS)
In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. Due to the play between screw and nail, the reduction can be lost and the instability can result in malunions…
- Conditions
- Humerus Fracture, Femur Fracture, Tibia Fracture
- Trial name
- ASLS-Pre (NCT00793637)
- Where
- 4 sites in Austria, Germany
- Volunteers
- 30 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Osteoarthritis, Knee, Rheumatoid Arthritis
A Comparison of Two Surgical Techniques Using the Unity Knee™ Total Knee System
A comparison of two Unity Knee™ tissue-balancing techniques by analysing the results from X-rays and patient questionnaires.
- Conditions
- Osteoarthritis, Knee, Rheumatoid Arthritis, Post-Traumatic Osteoarthritis of Knee, Varus Deformity, Not Elsewhere Classified, Knee
- Trial name
- NCT03511144
- Testing
- Unity Knee™ TKR using measured resection, Unity Knee™ TKR using ligament balancing
- Sponsor
- Corin
Femoral Fractures, Tibial Fractures
Reamed Locked Plating - Metaphyseal Fractures of the Distal Femur and Tibia
Comminuted metaphyseal fractures (OTA classification A2/3 and C2/3) of the distal femur and distal tibia are difficult to treat and typically have more complications than other metaphyseal fractures.
- Trial name
- NCT01553630
- Testing
- RIA bone graft, Surgery without bone graft
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- Florida Orthopaedic Institute
Distal Femur Fracture, Tibial Plateau Fracture
Early Advanced Weight Bearing for Peri-articular Knee and Pilon Injuries
The overall objective of this study is to compare outcomes following early advanced weight bearing (EAWB) using the AlterG antigravity treadmill versus standard of care physical therapy for adult patients with lower extremity…
- Conditions
- Distal Femur Fracture, Tibial Plateau Fracture, Distal Tibia Fracture, Pilon Fracture
- Trial name
- AlterG (NCT03562364)
- Testing
- AlterG anti-gravity treadmill
- Where
- 10 sites in United States
- Volunteers
- 81 people
- Sponsor
- Major Extremity Trauma Research Consortium
Tibial Fractures
Comminuted Intra-Articular Distal Tibia Fracture Fixation Using Computer Techniques
Comminuted intra-articular distal tibia fractures (OTA 43-C) typically are the result of high-energy trauma such as motor vehicle collisions or fall from a height.
- Trial name
- CIDUCT (NCT02845245)
- Testing
- 3D printed plastic model prototype, 3D CT scan, Plain film radiographs
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Inova Health Care Services
Tibia Fracture
Splinting Versus Not Splinting of the Distal Lower Extremity After Intramedullary Nailing for Tibial Fractures
Two standards of care exist with regards to posterior splinting post-operatively. The proponents of splinting feel the additional immobilization decreases the stress on the soft tissue, subsequently preventing or limiting pain…
- Trial name
- NCT00888550
- Testing
- Post-Op Splinting, No Splinting
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Denver Health and Hospital Authority
Tibia Fracture
Is the Expert Nail With Poller Screws Superior to the Distal Tibial Locked Plate in the Management of Short Oblique Distal Tibial Fractures?
Distal tibial fracture management is difficult because of poor blood supply resulted from subcutaneous location. Therefore, the study aims to compare expert intramedullary nail (IMN) with poller screws to the distal tibial locked…
- Trial name
- NCT06436365
- Testing
- Locking expert intramedullary nail fixation, Distal locked plate
- Where
- Egypt
- Volunteers
- 42 people
- Sponsor
- Kasr El Aini Hospital
Tibial Fractures, Epiphyseal Fracture
Study of Prognostic Factors of the Distal Epiphysis of the Tibia Fracture Prognosis
Background: Epiphysis of distal end of tibia fracture is quite common in children epiphysis injury, because of the complex damage mechanism and often leads to growth retardation and joint deformity, the patient's physical and…
- Trial name
- NCT02723825
- Testing
- Closed reduction, Open reduction
- Volunteers
- 200 people
- Sponsor
- Foshan Hospital of Traditional Chinese Medicine
Fracture Healing, Treatment Duration
Smart Crutch Tips for Guided Weight-Bearing in Patients Recovering From Extra-Articular Distal Tibia Fractures
The goal of this clinical trial is to learn whether personalized weight-bearing prescriptions using Smart Crutch Tips™ can improve recovery after surgery for extra-articular distal tibia fractures.
- Conditions
- Fracture Healing, Treatment Duration, Distal Tibia Fracture
- Trial name
- NCT07138066
- Testing
- Smart Crutch Tips™, Finite Element Analysis (FEA), Iterative walking
- Where
- 18 sites in Ukraine
- Volunteers
- 30 people
- Sponsor
- Comeback Mobility Inc
Tibial Fractures, Femoral Fractures
Distal Locking Using an Electromagnetic Field Guided Computer Based Real Time System for Orthopaedic Trauma Patients
Hypothesis: Utilization of the "wand" method will enhance improvements in drill placement, locking nail placement during tibia and femur fracture repairs, and offer less radiation exposure and less operative time.
- Trial name
- Sure Shot (NCT01183078)
- Testing
- free-hand, Wand technique
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Wake Forest University Health Sciences
Femur Fracture, Tibial Fractures
Distal Targeter vs Free-hand
This study is a randomized controlled trial comparing the use of two different surgical techniques--free-hand versus distal targeting jig-based for distal interlock screw--placement and their effects on total operative time and…
- Conditions
- Femur Fracture, Tibial Fractures, Nonunion of Fracture, Nonunion of Fracture of Tibia
- Trial name
- NCT05613257
- Testing
- Distal targeting jig, Free-hand/perfect circles technique
- Where
- United States
- Volunteers
- 89 people
- Sponsor
- Cedars-Sinai Medical Center
Pilon Fracture
Two-stage ORIF Vs Ex. Fix. in Complex Pilon Fractures
This study aims to compare the clinical, radiological, and functional outcomes of two-stage open reduction and internal fixation with single-stage external fixation in the treatment of comminuted tibial pilon fractures.
- Trial name
- NCT05141227
- Testing
- Two-stage Open reduction and internal fixation ( ORIF) using plates & screws, single-stage external fixation (EX.FIX.) with minimal internal fixation using cannulated screws if needed
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Fracture Non Union, Fracture Healing
Prospective Validation Study of the CD8+TEMRA Cells As a Prognostic Biomarker of Healing Outcome After Fracture
In approx. 10-15% of all fracture patients, there is a prolonged healing time or even a complete absence of fracture healing (non-union).
- Conditions
- Fracture Non Union, Fracture Healing, Long Bone Delayed-Union Fracture, Humerus Shaft Fracture
- Trial name
- BioBone (NCT06658379)
- Testing
- CD8+TEMRA
- Where
- 7 sites in Germany
- Volunteers
- 640 people
- Sponsor
- Charite University, Berlin, Germany
Hallux Valgus and Bunion (Disorder), Morton Neuroma
Feasibility of Specific Anesthesia of the Forefoot Preserving the Sensitivity of the Heel for Foot Surgery
Foot surgery is a painful surgery that is usually scheduled in outpatients. A good management of analgesia is the crucial point.
- Conditions
- Hallux Valgus and Bunion (Disorder), Morton Neuroma, Metatarsal Fracture, Ingrown Nail
- Trial name
- DISTIB (NCT03504462)
- Testing
- Specific block of medial and lateral plantar nerves
- Where
- France
- Volunteers
- 27 people
- Sponsor
- CMC Ambroise Paré
Femoral Neck Fractures, Intertrochanteric Fractures
Opioid-Free Pain Treatment in Trauma Patients
Analgesic drug study that will compare pain outcomes of opioid analgesia and opioid-free analgesia in post-operative orthopedic patients.
- Conditions
- Femoral Neck Fractures, Intertrochanteric Fractures, Femoral Shaft Fracture, Distal Femur Fracture
- Trial name
- NCT06078371
- Testing
- Opioid-free pain treatment
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- University of Kansas Medical Center
Osteoporosis, Diagnoses Disease
Normative Database for HR-pQCT-Based Radius and Tibia Strength
A novel methodology was recently developed and validated by the applicants to compute bone strength at the distal radius and tibia using second-generation HR-pQCT reconstructions.
- Conditions
- Osteoporosis, Diagnoses Disease, Fracture, Bone Strength
- Trial name
- NODARATIS (NCT03219099)
- Where
- Switzerland
- Volunteers
- 576 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Tibial Fractures
Trial to Evaluate the Effectiveness of Angular Stable Locking System (ASLS) in Patients With Distal Tibial Fractures
In many cases, the existing locking bolts and screws in intramedullary nails do not provide sufficient stability. The play between screw and nail can result in loss of reduction and the instability due to the interfragmentary…
- Trial name
- NCT00875992
- Testing
- ETN with ASLS, ETN locked with conventional locking bolts
- Where
- 8 sites in Austria, Germany and 1 more
- Volunteers
- 141 people
- Sponsor
- AO Clinical Investigation and Publishing Documentation
Orthopedic Disorder, Trauma Injury
X-BS Ortho Bone Graft Study
Randomised investigation of the osteoconductive performance and safety of CE-marked FDBS bone graft (GraftR3®), with contextual reference to CE-marked IBS (MBCP® Putty), in the filling of orthopaedic bone defects.
- Conditions
- Orthopedic Disorder, Trauma Injury, Extremity Injury
- Trial name
- NCT06326827
- Testing
- FDBS (GraftR3®), IBS (MBCP® Putty)
- Volunteers
- 200 people
- Sponsor
- Advanced Medical Solutions Ltd.
Tibia Distal Fracture, Nonunion of Fracture of Tibia
Is Far Cortical Locking More Effective Than Bicortical Locking in Treating AO 43A1-3 Fractures?
Delayed union or nonunion, which is a common complication of periarticular fractures repaired with angled locking plate systems, may be due to the unintentionally rigid formation of this system.
- Trial name
- NCT06005090
- Testing
- Far Cortical Locking Technique
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Saglik Bilimleri Universitesi