Clinical trials: Disuse Atrophy
Muscle Atrophy, Disuse Atrophy (Muscle) of Lower Leg
The Regulation of Human Skeletal Muscle Mass by Contractile Perturbation
It is well known that periods of weight training lead to increases in skeletal muscle size and strength. In contrast, periods of inactivity such as bed rest or immobilization result in losses of skeletal muscle size and strength.
- Trial name
- HYPAT (NCT03046095)
- Testing
- Unilateral Resistance Exercise, Immobilization
- Where
- Canada
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- McMaster University
Atrophy, Disuse, Insulin Resistance
Bedrest, Feeding Pattern, and Insulin Sensitivity
In the present study, the investigators will assess the impact of two different feeding patterns (continuous vs intermittent) on insulin sensitivity and muscle mass following bedrest.
- Trial name
- NCT02521025
- Testing
- Intermittent feeding pattern, Continuous feeding pattern
- Where
- Netherlands
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Disuse Atrophy
Bed-rest, Muscle Mass and Insulin Sensitivity
In the present study, the effects of 7 days of bed rest on muscle mass, muscle fiber characteristics and insulin sensitivity will be determined.
- Trial name
- NCT02109380
- Testing
- Bed rest
- Where
- Netherlands
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Disuse Atrophy, Aging
Immobilization and Protein Supplementation (IM-PRO)
In the present study, the effects of 5 days of lower limb immobilization with or without twice-daily protein supplementation on muscle mass and muscle fiber characteristics will be determined.
- Trial name
- IM-PRO (NCT01588808)
- Testing
- Immobilization
- Where
- Netherlands
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Disuse Atrophy, Immobilization
Electrical Stimulation During Immobilization
In the present study, the effects of 5 days of lower limb immobilization with or without daily neuromuscular electrical stimulation on muscle mass and muscle fiber characteristics will be determined.
- Conditions
- Disuse Atrophy, Immobilization, Neuromuscular Electrical Stimulation
- Trial name
- ESDIM (NCT01513486)
- Testing
- immobilization
- Where
- Netherlands
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Disuse Atrophy
Leucine Supplementation and Skeletal Muscle Disuse
Leucine supplementation is widely known for promoting strong influence on skeletal muscle remodeling. This study aims to evaluate the effect of leucine supplementation on disuse-induced skeletal muscle atrophy.
- Trial name
- NCT01192009
- Testing
- Leucine
- Where
- Brazil
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Multifidus Disuse Atrophy
Short Arc Multifidus Study
Patients will be performing Logan short arc banding protocols to see the effect on multifidus size
- Trial name
- NCT00846664
- Testing
- Logan Short Arc Banding
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Logan College of Chiropractic