Clinical trials: Diverticulosis, Colonic
Diverticulitis, Colonic
Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics
The objective of this clinical trial to evaluate the effectiveness and safety of outpatient treatment without antibiotics compared to outpatient treatment with antibiotics in patients with acute uncomplicated diverticulitis.
- Trial name
- ADIANA (NCT06517264)
- Testing
- Antibiotic, Non antibiotic
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Monica Mengual Ballester
Colonic Cancer, Rectal Cancer
Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Colonic Resection
Laparoscopic (key-hole) large bowel resection is a minimally invasive procedure when compared to open large bowel resection, but is still associated with a significant amount of pain and discomfort.
- Conditions
- Colonic Cancer, Rectal Cancer, Colonic Diverticulum, Ulcerative Colitis
- Trial name
- NCT01339273
- Testing
- Ultrasound guided Transversus Abdominis Plane (TAP) bock, Local anaesthetic infiltration of laparoscopic port sites
- Where
- United Kingdom
- Volunteers
- 72 people
- Sponsor
- Oxford University Hospitals NHS Trust
ColoRectal Cancer, Colonic Diverticulitis
Intraoperative Testing of Colorectal Anastomosis - Air or Water (Methylene Blue)?
A leak from a colorectal anastomosis is a post-operative complication surgeons fear the most, following colonic resection. Over the years, there have been multiple suggestions for intraoperative tests for the integrity of the…
- Conditions
- ColoRectal Cancer, Colonic Diverticulitis, Anastomotic Leak, Anastomotic Complication
- Trial name
- ITCORA (NCT03316677)
- Testing
- Intraoperative testing of colorectal anastomoses, Stapled colorectal anastomoses
- Volunteers
- 150 people
- Sponsor
- Meir Medical Center
Colo-rectal Cancer, Colo-rectal Surgery
Post Operative Hospital at Home After Colorectal Surgery
The goal of this feasibility study is to investigate whether a virtual Hospital at Home is safe and possible for patients undergoing planned minimally invasive colorectal surgery.
- Conditions
- Colo-rectal Cancer, Colo-rectal Surgery, Colocolic and Ileocolic Anastomosis, Colon and/or Rectal Resection With Anastomosis for Cancer
- Trial name
- POPHaH (NCT07113717)
- Testing
- virtual Hospital at Home
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Nordsjaellands Hospital
Diverticulitis, Acute Diverticulitis
Randomized Multicentric Trial to Evaluate a Free Diet With a Progressive Diet in the Treatment of Acute Diverticulitis (DIVERDIET)
Phase III trial is designed to demonstrate the non-inferiority of a free diet versus a progressive diet in the treatment of acute diverticulitis (AD) without complications.
- Conditions
- Diverticulitis, Acute Diverticulitis, Diverticulitis, Colonic, Uncomplicated Diverticular Disease
- Trial name
- NCT03496090
- Testing
- Free diet, Progressive diet
- Where
- Spain
- Volunteers
- 134 people
- Sponsor
- Hospital General Universitario Reina Sofía de Murcia
Gastrointestinal Hemorrhage, Colon Cancer
Bowel Preparation for Inpatient Colonoscopy
This study will compare two strategies for bowel cleansing prior to inpatient colonoscopy: the entire preparation taken the night before the procedure versus half the preparation taken the night before the procedure, and the…
- Conditions
- Gastrointestinal Hemorrhage, Colon Cancer, Diverticulosis
- Trial name
- NCT01169220
- Testing
- Go-Lytely, Go Lytely
- Where
- United States
- Volunteers
- 55 people
- Sponsor
- Santa Clara Valley Health & Hospital System
Outcome
Treatment in Right Colon Diverticulitis Patients
The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness.
- Trial name
- NCT04746326
- Testing
- Failure conservative treatment, Surgery, Conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Tepecik Training and Research Hospital
Diverticular Disease of Colon, Diverticulitis, Colonic
Evaluation of Laparoscopic Peritoneal Lavage for Perforated Diverticulitis: A National Registry - Based Study
The goal of this observational study is to study the emergency surgical treatment of diverticular disease in Sweden outside clinical trials.
- Conditions
- Diverticular Disease of Colon, Diverticulitis, Colonic, Peritonitis, Gastrointestinal Diseases
- Trial name
- NCT05893095
- Volunteers
- 52,863 people
- Sponsor
- Uppsala University Hospital
Diverticular Disease
Prophylactic Endoscopic Clipping of Diverticula (PECoD)
This study will evaluate the effect of endoscopic clipping of colonic diverticula in treatment of symptoms related to diverticular disease.
- Trial name
- PECoD (NCT03935100)
- Testing
- Endoscopic clipping
- Where
- United Kingdom
- Volunteers
- 84 people
- Sponsor
- King's College Hospital NHS Trust
Colonic Diverticulitis
The Out-patient, Non Antibiotic Management of Patients With Acute Uncomplicated Colonic Diverticulitis
Previous multicentre study NCT 01008488 indicates that a patient with CT-proven uncomplicated diverticulitis has a very low risk (1.4%) of developing severe complications such as perforations or abscesses.
- Trial name
- P-VOD (NCT01515150)
- Where
- Sweden
- Volunteers
- 161 people
- Sponsor
- Uppsala University
Colonic Diverticulitis
Prospective Evaluation of Quality of Life in Patients With Acute Colonic Diverticular Disease
A multicenter prospective observational study. Aim of the study is to identify the clinical parameters correlating with favorable outcomes in patients undergoing surgery or medical treatment for diverticular disease.
- Trial name
- DDR (NCT04907383)
- Testing
- quality of life
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Niguarda Hospital
Acute Complicated Diverticulitis, Colonic Diverticulitis
Management of Acute Complicated Diverticulitis: An Assessment of Current Practices
Acute complicated diverticulitis (ACD) is a frequent surgical emergency that can be life-threatening. It encompasses various clinical entities, including colonic perforations, abscesses (Hinchey II), fistulas, and purulent or…
- Trial name
- NCT07601958
- Where
- Belgium
- Volunteers
- 208 people
- Sponsor
- Jules Bordet Institute
Diverticulitis, Surgical Site Infection
Surgical Site Infection Outcomes in Natural Orifice Intracorporeal Anastomosis and Extraction (NICE) Procedure - The NICE Trial
The goal of this observational study is to learn if a new surgical technique, called the NICE procedure, is as safe as standard methods for treating benign left-sided colon and rectal diseases in adults.
- Conditions
- Diverticulitis, Surgical Site Infection, Surgical Site Infections, Colorectal Surgery
- Trial name
- NCT06957236
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- The Methodist Hospital Research Institute
Diverticulosis, Colonic, Abdominal Adhesion
Prior Abdominal Surgery: A Potential Risk Factor for Colonic Diverticulosis or Diverticulitis
Background \& Aims: Abnormal colonic pressure profiles have been associated with an increased risk of colonic diverticulosis. A surgical history is a known risk factor for abdominal adhesions, and these may lead to increased…
- Conditions
- Diverticulosis, Colonic, Abdominal Adhesion, Diverticulitis
- Trial name
- NCT05384925
- Testing
- comparison
- Where
- Israel
- Volunteers
- 359 people
- Sponsor
- Assaf-Harofeh Medical Center
Colonic Diverticulitis
Antibiotic Therapy of Acute Uncomplicated Colonic Diverticulitis
The purpose of this study is to evaluate if antibiotic therapy is necessary for treatment of uncomplicated colonic diverticulitis.
- Trial name
- NCT01008488
- Testing
- Antibiotic
- Where
- Sweden
- Volunteers
- 600 people
- Sponsor
- Uppsala University
Colon Neoplasms, Rectal Neoplasms
The Role of Indocyanine Green (ICG) Fluorescence Imaging on Anastomotic Leak in Robotic Colorectal Surgery
In colorectal surgery, anastomotic leak and its septic consequences still remain as the most concerning complications resulting in substantial morbidity and mortality.
- Conditions
- Colon Neoplasms, Rectal Neoplasms, Inflammatory Bowel Disease, Diverticular Disease
- Trial name
- NCT02598414
- Testing
- Near-infrared ICG fluorescence imaging, Traditional bowel anastomosis, FireFly™
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Acibadem University
Diverticulosis, Colonic, Microbiota
Influence of Mechanical Bowel Preparation on GI Microbiota
The mechanical bowel preparation (BP) used to clean the colon prior to colonoscopy frequently results in a significant but temporary reduction in patient's symptoms for a number of bowel disorders including symptomatic…
- Trial name
- NCT03465293
- Testing
- Bacterial composition and activity after bowel preparation
- Volunteers
- 15 people
- Sponsor
- University of Reading
Colon Adenoma, Diverticulosis
Impact of Diverticular Disease on the Detection of Colon Adenomas
Benign adenomas of the colon have the potential to degenerate and become malignant. Therefore adenomatous polyps should be detected and resected during colonoscopy.
- Trial name
- DECADE (NCT02057562)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Technical University of Munich
Hypertension, Depression
Patient-Centred Innovations for Persons With Multimorbidity - Ontario
The aim of Patient-Centred Innovations for Persons With Multimorbidity (PACE in MM) study is to reorient the health care system from a single disease focus to a multimorbidity focus; centre on not only disease but also the…
- Conditions
- Hypertension, Depression, Anxiety, Musculoskeletal Pain
- Trial name
- PACEinMM-ON (NCT02742597)
- Testing
- TIP / IMPACT Plus Care Coordination
- Where
- 9 sites in Canada
- Volunteers
- 175 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Biliary Disease, Gallstone; Cholecystitis, Acute
Multicentric Point of Care UltraSound by Surgeons Trial
Acute gallbladder pathology and acute diverticulitis are common conditions met in emergency departments and comprise the bulk of admissions throughout general surgical calls.
- Conditions
- Biliary Disease, Gallstone; Cholecystitis, Acute, Diverticulitis, Colonic, Abscess Pelvic
- Trial name
- POCUSS (NCT02682368)
- Testing
- Point of Care Ultrasound by Surgeons (POCUSS), Radiology report, Surgery-Intra-operative findings
- Where
- 5 sites in Ireland, Italy and 2 more
- Volunteers
- 183 people, healthy volunteers welcome
- Sponsor
- Connolly Hospital Blanchardstown