Clinical trials: Diverticulosis
Cesarean Section Complications
Endometrium Microbiome Alterations in Cesarean Section Diverticula Before and After Transvaginal Repair Surgery
The study compares the microbiome differences in the endometrium between normal people and patients with uterine diverticula after cesarean section and aims to discover the essential microbes and their metabolites that highly…
- Trial name
- NCT04847154
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Diverticular Disease
Prophylactic Elective Clipping of Colonic Diverticula
Diverticular bleeding is the most common cause of acute lower gastrointestinal bleeding (LGIB) in Western populations. Although self-limited in 85% of cases, some patients may require hospitalization with blood transfusion and…
- Trial name
- NCT02094456
- Testing
- Endoscopic clipping of diverticula, Follow-up colonoscopy
- Where
- United Kingdom
- Volunteers
- 9 people
- Sponsor
- King's College Hospital NHS Trust
Diverticular Disease
Bacterial Contamination in Transrectal Hybrid NOTES Sigmoidectomy
Transrectal Hybrid natural orifice translumenal endoscopic surgery sigmoidectomy has gained popularity. It is an appealing technique as a minilaparotomy in order to retrieve the specimen is avoided.
- Trial name
- NCT02500992
- Testing
- Transrectal sigmoidectomy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Cantonal Hospital, Baselland
Colorectal Cancer, Colorectal Neoplasms
Indocyanine Green Fluorescence Imaging in Prevention of Colorectal Anastomotic Leakage
This is a randomized, controlled, parallel, multicenter trial to determine the difference in post-operative anastomotic leakages in colorectal surgery, where anastomosis perfusion is evaluated using indocyanine green fluorescence…
- Conditions
- Colorectal Cancer, Colorectal Neoplasms, Gastrointestinal Cancer, Gastrointestinal Neoplasms
- Trial name
- ICG-COLORAL (NCT03602677)
- Testing
- ICG fluorescence imaging
- Where
- 2 sites in Finland
- Volunteers
- 1,062 people
- Sponsor
- Oulu University Hospital
Neoplasm, Diverticular Disease
Peri-Operative Management of Patients Undergoing Laparoscopic Colorectal Surgery
The aim is to ascertain which method out of epidural, spinal or patient controlled analgesia (PCA) is the most appropriate in fluid optimised patients after laparoscopic colorectal surgery in terms of pain control, length of…
- Conditions
- Neoplasm, Diverticular Disease, Analgesia
- Trial name
- NCT00747292
- Testing
- epidural, PCA, Spinal
- Where
- United Kingdom
- Volunteers
- 99 people
- Sponsor
- Minimal Access Therapy Training Unit
Zenker Diverticulum
Evaluation of Peroral Endoscopic Myotomy to Treat Zenker's Diverticulum
This is a multicenter investigator-initiated trial between Baylor-Scotts \& White (BSW) and Methodist Health System (MHS). This study will be conducted via a retrospective review and a prospective patient registry.
- Trial name
- ZPOEM (NCT05157984)
- Testing
- ZPOEM
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Methodist Health System
Colorectal Cancer, Diverticulitis Colon
Seal-G MIST (Minimally Invasive Sealant/Spray Technology) System Safety Study [SEALAR Study]
The purpose of this study is to evaluate safety of Seal-G MIST System in reinforcing colorectal anastomosis, in subjects undergoing colorectal surgery.
- Trial name
- SEALAR (NCT03448874)
- Testing
- Seal-G MIST System
- Sponsor
- Sealantis Ltd.
Colonic Diverticulitis
Prospective Evaluation of Quality of Life in Patients With Acute Colonic Diverticular Disease
A multicenter prospective observational study. Aim of the study is to identify the clinical parameters correlating with favorable outcomes in patients undergoing surgery or medical treatment for diverticular disease.
- Trial name
- DDR (NCT04907383)
- Testing
- quality of life
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- Niguarda Hospital
Diverticular Disease of the Colon
Mesalazine and/or Lactobacillus Casei in the Diverticular Disease of the Colon
This is a multi-centre, randomised, double blind, double-dummy, parallel groups, placebo-controlled trial was conducted in a population of patients suffering from symptomatic uncomplicated diverticular disease in order to…
- Trial name
- NCT01534754
- Testing
- Mesalazine plus Lactobacillus casei, Mesalazine 800 mg, Lactobacillus casei
- Where
- 14 sites in Italy
- Volunteers
- 250 people
- Sponsor
- Hospital Cristo Re
Zenker Diverticulum, Progressive Dysphagia
Cricopharyngeal Dysfunction and Esophageal Diverticulum
Patients undergoing open transcervical or endoscopic approach in which a laser or stapler is used to divide the common wall between the diverticulum and esophagus, or who are not surgical candidates but agree to follow-up.
- Conditions
- Zenker Diverticulum, Progressive Dysphagia, Pharyngoesophageal Diverticulum
- Trial name
- NCT03187925
- Testing
- open, transcervical versus rigid endoscopic treatment
- Where
- United States
- Volunteers
- 500 people
- Sponsor
- University of Cincinnati
Diverticulitis, Diverticulosis
The Gut Microbiome in Diverticulitis and Diverticulosis
Colonic diverticula are outpouchings of the large bowel, and they occur in up to 60% of people over 60 years of age. About 10-25% of patients with diverticula will have symptoms.
- Conditions
- Diverticulitis, Diverticulosis, Diverticular Disease
- Trial name
- NCT02221713
- Where
- United Kingdom
- Sponsor
- King's College Hospital NHS Trust
Outcome
Treatment in Right Colon Diverticulitis Patients
The right colon diverticula, unlike those in the left colon, contain all layers of the colon and is called the true diverticulum. Perforation is observed less frequently due to its full thickness.
- Trial name
- NCT04746326
- Testing
- Failure conservative treatment, Surgery, Conservative treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Tepecik Training and Research Hospital
Diverticulum, Colon, Colorectal Neoplasms
Data Collection of Patients Treated With the ColonRing™ for the Creation of Circular Compression Anastomosis
The proposed study is a post marketing, observational, retrospective data collection intended to gather and record data on patients treated with the ColonRing™ device in routine clinical practice at a single center.
- Conditions
- Diverticulum, Colon, Colorectal Neoplasms, Crohn Disease, Colitis, Ulcerative
- Trial name
- RETROPRESS (NCT01301417)
- Testing
- ColonRing™
- Where
- United States
- Volunteers
- 171 people
- Sponsor
- novoGI
Infertile Patients With Previous Live Birth
The Outcome and Influence Factors of Assisted Reproductive Therapy in Patients With Cesarean Scar Uterus.
Mode of delivery affects the success rate of assisted reproductive techniques (ART). In this case study, the investigators will evaluate changes in the bacterial ecology and inflammatory markers of the female uterus with…
- Trial name
- NCT04070222
- Testing
- Hysteroscopy
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Circumferential Female Urethral Diverticulum
Transvaginal Diverticulum Wall Filling and Coverage Technique for Treating Female Circumferential Urethral Diverticulum
The goal of this clinical study is to learn if a new surgical technique called transvaginal diverticular wall filling and covering is effective and safe for treating circumferential urethral diverticulum (UD) in female patients.
- Trial name
- NCT07006753
- Testing
- Transvaginal Diverticulum Wall Filling and Coverage Technique, Conventional surgery
- Where
- China
- Volunteers
- 100 people
- Sponsor
- West China Hospital
Diverticular Disease of Colon, Colostomy - Stoma
ARES Trial: Approach to Resection and Evaluation in Severe Diverticulitis
This observational study was conducted across five surgical centers in Italy, including both academic and community hospitals, from January 2017 to December 2022.
- Conditions
- Diverticular Disease of Colon, Colostomy - Stoma, Loop Ileostomies
- Trial name
- ARES (NCT07094594)
- Where
- Italy
- Volunteers
- 578 people
- Sponsor
- Azienda Sanitaria Locale Napoli 2 Nord
Oesophageal Disease
Endomina Diverticulum
Esophageal diverticulum is a rare disease. Majority comes form the pharyngo-esophageal junction (70 % Zenker's Diverticulum), 10% are mediothoracic and 20% epiphrenic.
- Trial name
- NCT03609073
- Testing
- Endomina
- Where
- Belgium
- Volunteers
- 4 people
- Sponsor
- Erasme University Hospital
Colon Adenoma, Diverticulosis
Impact of Diverticular Disease on the Detection of Colon Adenomas
Benign adenomas of the colon have the potential to degenerate and become malignant. Therefore adenomatous polyps should be detected and resected during colonoscopy.
- Trial name
- DECADE (NCT02057562)
- Where
- 2 sites in Germany
- Volunteers
- 1,000 people
- Sponsor
- Technical University of Munich
Diverticulitis, Colonic
Effectiveness and Safety of Outpatient Treatment of Uncomplicated Acute Diverticulitis Without Antibiotics
The objective of this clinical trial to evaluate the effectiveness and safety of outpatient treatment without antibiotics compared to outpatient treatment with antibiotics in patients with acute uncomplicated diverticulitis.
- Trial name
- ADIANA (NCT06517264)
- Testing
- Antibiotic, Non antibiotic
- Where
- Spain
- Volunteers
- 282 people
- Sponsor
- Monica Mengual Ballester
Zenker Diverticulum, Polyp of Colon
Advanced Endo-therapeutic Procedure : Registry-based Observational Study
Advanced therapeutic endoscopy procedures are of increasing importance to provide minimal invasive treatment for GI diseases. The Centre Hospitalier de l'Université de Montréal as tertiary university center is dedicated to…
- Conditions
- Zenker Diverticulum, Polyp of Colon, Colo-rectal Cancer
- Trial name
- AE Registry (NCT04117100)
- Testing
- Polypectomy or myotomy
- Where
- Canada
- Volunteers
- 500 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)