Clinical trials: Dobutamine
Shock
Dobutamine in the Treatment of Haemodynamic Insufficiency in the Immediate Postnatal Period
Haemodynamic insufficiency after birth is seen commonly in babies born prematurely and is associated with adverse outcomes. In current clinical practice, a combination of blood pressure and clinical signs is used to guide…
- Trial name
- NeoCirc-001 (NCT03311178)
- Testing
- Dobutamine
- Where
- Spain
- Volunteers
- 15 people
- Sponsor
- Fundacion para la Investigacion Biomedica del Hospital Universitario la Paz
Myocardial Infarction
Timing of Complete Revascularization for Multivessel Coronary Artery Disease in STEMI
The study will compare clinical outcomes between complete revascularization during hospitalization for ST elevation myocardial infarction (STEMI) and intervention after 30 days and intervention based on outpatient non-invasive…
- Trial name
- MVD (NCT02756000)
- Testing
- PCI, dobutamine stress echocardiography
- Where
- 4 sites in Serbia
- Volunteers
- 120 people
- Sponsor
- Clinical Hospital Center Zemun
Arrhythmias, Cardiac
Dobutamine on the Cardiac Conduction System
Our hypothesis is that Dobutamine will act in a similar fashion to Isoproterenol with respect to cardiac conduction. Our goal is to study the effects of Dobutamine on cardiac conduction and refractoriness during an…
- Trial name
- NCT04249258
- Testing
- Dobutamine
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Ischemic Heart Disease, Myocardial Infarction
Low-Dose Dobutamine Tc-99m-Mibi Gated SPECT to Predict Left Ventricular Remodelling in Patients Reperfused in the Acute Phase of MI
Left myocardial infarction (MI), has a negative impact of long term morbidity and mortality. Even in patients treated successfully by angioplasty in the acute phase of infarct, the remodelling is observed in approximately 30% of…
- Trial name
- NCT00487812
- Testing
- Low-dose dobutamine Tc-99-m-mibi gated SPECT imaging
- Where
- France
- Volunteers
- 50 people
- Sponsor
- University Hospital, Clermont-Ferrand
Patients With Septic Shock, Surgical Patients
Dobutamine for Management of Surgical Patients With Septic Shock
Septic shock is the last and most severe stage of sepsis and is defined by extremely low blood pressure, despite lots of intravenous fluids. The incidence of septic shock related cardiomyopathy was 10% to 70%.
- Conditions
- Patients With Septic Shock, Surgical Patients, General Anesthesia
- Trial name
- NCT06462313
- Testing
- Dobutamine, Norepinephrine
- Where
- China
- Volunteers
- 584 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Acute Heart Failure
Survival of Patients With Acute Heart Failure in Need of Intravenous Inotropic Support: a Multicentre, Parallel-Group, Randomised, Double-Blind, Double-Dummy Study of Levosimendan Versus Dobutamine in Patients With Acute Heart Failure.
The primary objective of the study is to compare the efficacy of levosimendan and dobutamine on all-cause mortality in the 180 days following randomization.
- Trial name
- NCT00348504
- Testing
- levosimendan, dobutamine
- Where
- United States
- Volunteers
- 1,300 people
- Sponsor
- Abbott
Cardiogenic Shock, Septic Shock
Levosimendan Versus Dobutamine in Shock Patients
The purpose of the study is to compare the efficacy of levosimendan with that of dobutamine in patients with unstable hemodynamics (shock).
- Trial name
- NCT00093301
- Testing
- Levosimendan, Dobutamine
- Where
- Australia
- Volunteers
- 40 people
- Sponsor
- Wentworth Area Health Services
Coronary Artery Disease
Hemodynamic Forces at Rest and Stress vs. Adenosine and Dobutamine Stress Cardiac Magnetic Resonance
Stress perfusion CMR has recently considered as one of the methods of choice for establishing the diagnosis of CAD based on its high diagnostic accuracy, lack of ionizing radiation as well as its ability to simultaneously assess…
- Trial name
- CMR (NCT04247698)
- Where
- Egypt
- Volunteers
- 112 people
- Sponsor
- Assiut University
Coronary Artery Disease, Echocardiography, Stress
New Three-dimensional Methods of Analysis for the Detection of Coronary Artery Disease by Dobutamine Stress Echocardiography
The investigators are going to recruit patients who have a scheduled elective coronary angiography and going to do a dobutamin stress echography (DSE) before the coronary examination.
- Trial name
- 3-DSE (NCT02240745)
- Testing
- Stress-echocardiography
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Dobutamine, Milrinone , Pediatrics , Low Cardiac Output
Dobutamine Versus Milrinone in Management of Critically Ill Low Cardiac Output Pediatric Patients at Cairo University Children's Hospital
The aim of the study is to detect wither dobutamine or milrinone have a privilege in the management of low cardiac output pediatric patients over the other.
- Trial name
- NCT05999487
- Testing
- Dobutamine
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Critical Illness
Vasopressor Support, Mean Arterial Pressure and Capillary Refill Time in Critically Ill Patients
The goal of this observational study is to learn whether different doses of various vasopressor drugs influence capillary refill time (CRT) value in crtically ill patients.
- Trial name
- NCT05674084
- Testing
- Capillary refill time
- Where
- Poland
- Volunteers
- 150 people
- Sponsor
- Medical University of Silesia
Septic Shock
Effects of Levosimendan on Microcirculation in Septic Shock
The present study was conducted as a prospective, randomized, controlled study to: investigate the effects of a combination of levosimendan and inhaled nitric oxide on systemic hemodynamics and microcirculation in patients with…
- Trial name
- NCT00800306
- Testing
- Levosimendan, dobutamine
- Where
- Italy
- Volunteers
- 40 people
- Sponsor
- University of Roma La Sapienza
Myocardial Blood Flow Reserve, Mechanical Dyssynchrony
Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT
The project is aimed at studying the feasibility of mechanical dyssynchrony of the left ventricle of the heart, determined by SPECT (gated MPI), as well as its stress-induced dynamics, in the evaluation of patients with coronary…
- Conditions
- Myocardial Blood Flow Reserve, Mechanical Dyssynchrony, Coronary Arterial Disease (CAD)
- Trial name
- MD&MD (NCT06969547)
- Testing
- dynamic SPECT (two-day rest/stress protocol), gated myocardial perfusion imaging, blood sampling
- Where
- Russia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Hemodynamic Instability
Dobutamine Versus Placebo for Low Superior Vena Cava Flow in Newborns
Low systemic flow as measured by Doppler-echocardiography has been associated with poor neurological outcome. Yet, it has not been systematically evaluated whether the treatment of this hemodynamic condition is beneficial or not.
- Trial name
- NCT01605279
- Testing
- Dobutamine
- Where
- Spain
- Volunteers
- 127 people
- Sponsor
- Adelina Pellicer
Kidney Transplantation, Pancreas Transplantation
Pre-operative Evaluation of Kidney & Pancreas Transplant Patients
Examine the clinical utility of the dobutamine stress contrast echoes and angiograms obtained routinely in the evaluation of patients prior to kidney or pancreas transplantation.
- Trial name
- NCT00580437
- Testing
- Dobutamine Stress Echocardiogram
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Nebraska
Nfuence of Vasoactive Medication on Spinal Oxygenation
Influence of Continuous Administration of Phenylephrine Versus Dobutamine on Spinal Oxygen Saturation, Measured With Near-infrared Spectroscopy (NIRS).
To assess the effect of hemodynamic supportive medication on spinal vasculature, patients scheduled for arterial dilation of the lower limb were chosen as our study population.
- Trial name
- NIRS continu (NCT03846765)
- Testing
- Phenylephrine, Dobutamine
- Where
- Belgium
- Volunteers
- 36 people
- Sponsor
- University Hospital, Ghent
Vasculopathy, Allograft
Cardiac Allograft Vasculopathy and Dobutamine Stress Echocardiography / Brain Natriuretic Peptide Coupling
Primary purpose :To early detect cardiac allograft vasculopathy and to identify patients with high risk of cardiac events, by coupling the analysis of the kinetics of the brain natriuretic peptide ( BNP) with that of the left…
- Trial name
- NCT00384540
- Testing
- Dobutamine stress echocardiography, coronarography, brachial arterial echography
- Where
- France
- Volunteers
- 53 people
- Sponsor
- University Hospital, Strasbourg, France
Cardiogenic Shock, Heart Failure
Left Ventricular Volume Index in the Adjustment of Initial Dose of Dobutamine in Heart Failure and Cardiogenic Shock
Recent studies have suggested that the use of left ventricular ejection volume index calculation may aid in the hemodynamic management of critically ill patients.
- Trial name
- NCT03727282
- Testing
- adjust dobutamine according to the ejection volume index, adjust dobutamine according to the attending physician
- Volunteers
- 30 people
- Sponsor
- University of Sao Paulo General Hospital
Heart Failure
Efficacy and Safety of Treatment With Simdax® Versus Dobutrex® in Decompensated Heart Failure Patients.
The purpose of this study is to compare the effects of levosimendan with dobutamine on heart function in patients suffering of severe chronic heart failure.
- Trial name
- NCT00219388
- Testing
- Levosimendan
- Where
- Sweden
- Volunteers
- 60 people
- Sponsor
- Orion Corporation, Orion Pharma
Heart Failure
Outcome and Safety of Intermittent Dobutamine Infusion at a Day-Care Center in Advanced Heart Failure Patients
Heart failure (HF) is a prevalent disease reaching 1-2% of adult population in developed countries, and 10% in patients over 70 years.
- Trial name
- DoBHF (NCT01930734)
- Testing
- Dobutamine, Normal Saline
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Sheba Medical Center