Clinical trials: Dobutamine
Arrhythmias, Cardiac
Dobutamine on the Cardiac Conduction System
Our hypothesis is that Dobutamine will act in a similar fashion to Isoproterenol with respect to cardiac conduction. Our goal is to study the effects of Dobutamine on cardiac conduction and refractoriness during an…
- Trial name
- NCT04249258
- Testing
- Dobutamine
- Where
- United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Coronary Artery Disease, Echocardiography, Stress
New Three-dimensional Methods of Analysis for the Detection of Coronary Artery Disease by Dobutamine Stress Echocardiography
The investigators are going to recruit patients who have a scheduled elective coronary angiography and going to do a dobutamin stress echography (DSE) before the coronary examination.
- Trial name
- 3-DSE (NCT02240745)
- Testing
- Stress-echocardiography
- Where
- Switzerland
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Myocardial Blood Flow Reserve, Mechanical Dyssynchrony
Mechanical Dyssynchrony and Microvascular Dysfunction by SPECT
The project is aimed at studying the feasibility of mechanical dyssynchrony of the left ventricle of the heart, determined by SPECT (gated MPI), as well as its stress-induced dynamics, in the evaluation of patients with coronary…
- Conditions
- Myocardial Blood Flow Reserve, Mechanical Dyssynchrony, Coronary Arterial Disease (CAD)
- Trial name
- MD&MD (NCT06969547)
- Testing
- dynamic SPECT (two-day rest/stress protocol), gated myocardial perfusion imaging, blood sampling
- Where
- Russia
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Tomsk National Research Medical Center of the Russian Academy of Sciences
Mortality After Major Non Cardiac Surgery
Intraoperative Dobutamine Stress Test With Speckle Tracking to Decrease Postoperative Mortality (ISTMO)
Perioperative adverse cardiovascular events are the leading cause of morbidity and mortality after noncardiac surgery. The implications of perioperative cardiac complications on morbidity and mortality, in-hospital and long-term…
- Trial name
- ISTMO (NCT03365726)
- Testing
- Dobutamine stress test with trans-esophageal echocardiography
- Where
- Canada
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Cirrhosis, Cirrhotic Cardiomyopathy
DOCICAR: Cardiac Dysfunction in Cirrhosis
Patients with cirrhosis have a altered cardiac response to stress. This study evaluate the cardiac response by MRI during dobutamine stress. Hypothesis: impared increase in cardiac output, cardiac index, ejection fraction.
- Trial name
- NCT00250315
- Testing
- Dobutamine
- Where
- Denmark
- Volunteers
- healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Heart Failure
Right Ventricular Contractile Reserve in HF
Right ventricle dysfunction and pulmonary hypertension are related to a worse prognosis in patients with heart failure with reduced left ventricular ejection fraction (HFrEF) or with normal left ventricular ejection fraction…
- Trial name
- RISE-HF (NCT05797584)
- Testing
- Dobutamine, Passive leg raising
- Where
- Italy
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Istituto Auxologico Italiano
Ischemic Cardiomyopathy
Stress Cardiac MRI in Ischemic Patients
The aim of this study is to assess the diagnostic accuracy of CMR feature-tracking (FT) at rest \& during stress with low dose dobutamine (LDD) in the evaluation of viability in ischemic cardiomyopathy (ICM) patients and compare…
- Trial name
- NCT04588675
- Testing
- MRI
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Assiut University
Lung Cancer, Surgery
CMR Right Ventricular Contractile Reserve Following Lung Resection
Feasibility study investigating CMR dobutamine stress testing before and after lung resection
- Conditions
- Lung Cancer, Surgery, Anesthesia
- Trial name
- NCT06465277
- Testing
- Dobutamine stress CMR, Cardiac biomarker sample
- Where
- United Kingdom
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Belfast Health and Social Care Trust
Coronary Artery Disease
Strain-Encoded Cardiac Magnetic Resonance Imaging for Dobutamine Stress Testing
The purpose of this study is to compare the diagnostic value of SENC to that provided by conventional wall motion analysis for the detection of inducible ischemia during DS-MRI.High-dose dobutamine stress magnetic resonance…
- Trial name
- NCT00758654
- Where
- Germany
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Heidelberg University
Kawasaki Disease, Heart Disease
Real Time Myocardial Contrast Echocardiography and Dobutamine Stress Perfusion Magnetic Resonance Imaging
The present study is designed to: 1. investigate the safety and efficacy of Real time myocardial echocardiography (RT-MCE) in adolescents and adults ages 12-50 with congenital and acquired congenital heart disease 2.
- Trial name
- ECHOBIKE (NCT00861848)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University of Nebraska
Healthy, Heart Failure
The Hemodynamic Response to Prolonged Dobutamine Infusion
A decrease in the response of beta 1 adrenergic receptors to agonists (desensitization) is thought to play a major role in the pathogenesis of diseases such as congestive heart failure.
- Trial name
- NCT01042873
- Testing
- 3 hours intravenous dobutamine
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
Diastolic Dysfunction
Early Diagnosis of Diastolic Dysfunction and Reliability of DSE in Detecting Stress Diastolic Dysfunction
The heart becoming "stiff" due to increased fibrous tissue or decreased elasticity of the heart tissue is one of the earliest changes caused by heart failure.
- Trial name
- NCT00998205
- Testing
- Dobutamine stress echo (DSE), Atropine bolus
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Diabetes-related Complications
Myocardial Regional Function by Dobutamine Stress Echocardiography in the Metabolic Syndrome and Type 2 Diabetes
Summary. Theoretical Rationale: The left ventricular myocardial performance results from a complex interplay between linear deformations (longitudinal, circumferential and radial) and twist/ untwist mechanics.
- Trial name
- NCT02505451
- Testing
- dobutamine
- Where
- France
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- University of Avignon