Clinical trials: Drinking, Alcohol
Alcohol Abuse, Alcohol Dependence
Internet-based vs Face-to-face Treatment for Alcohol Dependence
A brief treatment program (MI/CBT) via face-to-face or via internet is tested in association with an outpatient addictions clinic.
- Conditions
- Alcohol Abuse, Alcohol Dependence, Harmful Alcohol Use, Alcohol Use Disorder
- Trial name
- IMS (NCT02888002)
- Testing
- Guide to better alcohol habits
- Where
- Sweden
- Volunteers
- 310 people
- Sponsor
- Karolinska Institutet
Alcohol Consumption
Motivational Interventions for Lifestyle and Exercise in College Students
Engagement in substance-free activities, such as exercise, has an inverse relationship to substance use in college students. While exercise has numerous physical and mental health benefits, the majority of college students are…
- Trial name
- MILE (NCT01057979)
- Testing
- MET + CM for Exercise, MET + Exercise Contracting
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- University of Connecticut
Alcohol Use Disorder
Pilot Trial to Evaluate PROblem Solving Therapy and APPLE Watch for College Students
The goals of this Pilot Trial are to test the preliminary efficacy of Problom-Solving Therapy (PST)-APPLE Watch in a 2-arm pilot Randomized Control Trial (RCT), vs education only-control to reduce alcohol use disorder symptoms…
- Trial name
- NCT06333288
- Testing
- PST-APPLE Watch group, Education-only control group
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Illinois at Chicago
Alcohol Use Disorder
Imaging Inflammation With Alcohol Use Disorder: an [18F]NOS Study
Study to enroll up to 90 individuals, those with an alcohol use disorder (AUD) (up to n=60) and non-dependent healthy volunteers (HV) (up to n=30).
- Trial name
- AUD (NCT05885594)
- Testing
- [18F]NOS
- Where
- United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Psychosis, Alcohol Use Disorder
Effects of Action-Based Cognitive Remediation on Substance Misuse in Early Phase Psychosis
Psychotic disorders impact 4.6 people per 1000 globally, with approximately 1.5 million Canadians affected. The age of onset for psychotic disorders often begin during the critical years of youth and early adulthood, resulting in…
- Conditions
- Psychosis, Alcohol Use Disorder, Cannabis Use Disorder
- Trial name
- NCT07056894
- Testing
- Action-Based Cognitive Remediation
- Where
- 2 sites in Canada
- Volunteers
- 50 people
- Sponsor
- Nova Scotia Health Authority
Alcohol Consumption
Accountability Support Through Peer-Inspired Relationships and Engagement (ASPIRE) Trial
This project aims to test the efficacy of a text message intervention, ASPIRE, designed to address cognitive and behavioral elements and modify exposure to peers that influence drinking behaviors.
- Trial name
- ASPIRE (NCT06617702)
- Testing
- A text message alcohol intervention focused on cognitive, behavioral, and peer influences, A text message alcohol intervention focused on cognitive and behavioral influences
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Stanford University
Alcohol Use Disorder
Ibudilast for the Treatment of Alcohol Use Disorder
This study is a double-blind, placebo-controlled randomized clinical trial of Ibudilast (IBUD) (50mg twice a day) for the treatment of Alcohol Use Disorder (AUD).
- Trial name
- NCT03594435
- Testing
- Ibudilast
- Where
- United States
- Volunteers
- 102 people
- Sponsor
- University of California, Los Angeles
Alcohol Use Disorder
Study of Mindfulness Practice Efficacy in Alcoholic Relapse Prevention
Among behavioral cognitive psychotherapies, new "Mindfulness" interventions allow patient to identify, pay attention and accept external (sensory stimuli) and internal (cognition and emotions) phenomena.
- Trial name
- Mindfulness (NCT03150550)
- Testing
- Mindfulness practice, Relapse prevention
- Where
- France
- Volunteers
- 200 people
- Sponsor
- University Hospital, Clermont-Ferrand
Alcohol Drinking
The Drinking Dashboard Study
This study aims to develop and pilot test the efficacy of a "Drinking Dashboard" providing participants weekly feedback on the risk factors and consequences of blackout.
- Trial name
- NCT05630625
- Testing
- Drinking Dashboard
- Where
- United States
- Volunteers
- 169 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
AODD and AODR Disorder
The Efficacy of Brief Motivational Interviewing for Trauma Patients Related to Alcohol or Other Abuse Drugs.
The purpose of this study is to determine whether the Brief Motivational Interview will produce a significantly reduction in risk behavior than usual treatment 3 months after discharge from hospital in people who have survived a…
- Trial name
- MOTIVA (NCT02159391)
- Testing
- Brief Motivational Interview
- Where
- Spain
- Volunteers
- 86 people
- Sponsor
- Fundación Pública Andaluza para la Investigación Biomédica Andalucía Oriental
Alcohol, Alcohol Use Disorders
A Phase I Study of the Interaction of Alcohol With Oral AFA-281 in Healthy Volunteers
The goal of this clinical trial is to evaluate if alcohol interacts with the drug candidate AFA-281 in adults (healthy volunteers). This trial will evaluate blood concentration levels of AFA-281 and ethanol.
- Trial name
- NCT06719908
- Testing
- AFA-281 is a small molecule, orally available, Alcohol (Ethanol)
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Afasci Inc
Opioid Use, Alcohol Use Disorder
rTMS as Add on Treatment for Substance Use Disorders
This pilot study is designed to test feasibility and superiority of rTMS types and target locations for the optimal rTMS intervention for individuals seeking treatment for Alcohol Use Disorder (AUD) or Opioid Use Disorder (OUD).
- Trial name
- NCT06963476
- Testing
- repetitive transcranial magnetic stimulation (rTMS) for AUD, repetitive transcranial magnetic stimulation (rTMS) for OUD
- Where
- United States
- Volunteers
- 47 people
- Sponsor
- Yale University
Alcohol Use Disorder
Inpatient Alcohol Detox & Psychotherapy
The aim of the study is to evaluate effectiveness of inpatient detoxification and psycho-therapeutic support, measured in terms of readiness to change and abstinence maintenance.
- Trial name
- NCT03988478
- Testing
- Detoxification & psychotherapeutic support
- Volunteers
- 109 people
- Sponsor
- Tribhuvan University, Nepal
Alcohol Use Disorder, Substance Use Disorders
A Dialectical Behavioral Therapy Digital Health Solution for Outpatients Seeking Support for Substance Use
The purpose of this study is to compare the feasibility, acceptability, and efficacy of a dialectical behavior therapy skills training webapp known as "Pocket Skills" in outpatients and community members seeking treatment for…
- Trial name
- NCT05094440
- Testing
- Dialectical behavioral therapy skills training (DBT-ST)
- Where
- Canada
- Volunteers
- 76 people
- Sponsor
- Centre for Addiction and Mental Health
Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis
CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome
The aim is to determine the metabolic factors, host immune factors, and medical imaging data associated with the development of HepatoCellular Carcinoma (HCC) in patients with alcohol-related liver disease or dysmetabolic…
- Conditions
- Non-Alcoholic Fatty Liver Disease, Non-Alcoholic Steatohepatitis, Alcohol-related Liver Disease, Cirrhosis, Liver
- Trial name
- CHALNA2 (NCT05623150)
- Testing
- Liver biopsy
- Where
- France
- Volunteers
- 710 people
- Sponsor
- Institut National de la Santé Et de la Recherche Médicale, France
Alcohol Use Disorder
Self Management and Recovery Training (SMART) Recovery Study
This study identifies whether and how online support groups may work to confer therapeutic benefits onto its participants.
- Trial name
- SMART (NCT05756114)
- Testing
- Support Group, Psychoeducational Email
- Sponsor
- Yale University
Heavy Drinking
Interactive Alcohol Decision-Making Programs
This project aims to develop a maximally effective, computer-delivered brief intervention (CDBI) for reducing heavy alcohol use.
- Trial name
- NCT05398315
- Testing
- Empathic Statements/Reflections, Narrator Backstory, Male Narrator
- Where
- United States
- Volunteers
- 352 people, healthy volunteers welcome
- Sponsor
- Wayne State University
Alcohol Drinking, Pain
Personalized Feedback Intervention for Alcohol and Opioid Use Among Adults With Chronic Pain
Over one-quarter of American adults engage in hazardous drinking (i.e., a pattern of alcohol consumption that increases risk for harmful consequences), which is the third leading cause of preventable death in the U.S.
- Conditions
- Alcohol Drinking, Pain, Opioid Use, Feedback, Psychological
- Trial name
- NCT04592978
- Testing
- Pain-Alcohol Personalized Feeback Intervention, Control Personalized Feedback Intervention
- Where
- United States
- Volunteers
- 206 people
- Sponsor
- Syracuse University
Alcohol Use, Alcohol Drinking
Young Adult Naturalistic Alcohol Study (YANAS) Using Smartphone Technology in a Simulated Laboratory Environment
It is important to explore use of technology to reduce drinking. The purpose of this research study is to compare different types of mobile technology for their effects on alcohol drinking and ratings of usability among young…
- Conditions
- Alcohol Use, Alcohol Drinking, Drinking Behavior
- Trial name
- NCT02841735
- Testing
- Smartphone breathalyzer device/app use, BAC estimator app use, Text messaging procedure
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Consumption, PrEP Uptake
Enhancing HIV Prevention and Reducing Alcohol Use Among People Receiving STI Care in Lilongwe, Malawi
Purpose: To evaluate short-term efficacy and implementation of Treat4All, an alcohol reduction evidence-based intervention, for decreasing heavy drinking and optimizing HIV outcomes (viral suppression among People with HIV (PWH)…
- Conditions
- Alcohol Consumption, PrEP Uptake, Recent Heavy Drinking, HIV Prevention
- Trial name
- Treat4All (NCT06668363)
- Testing
- Treat4All, Standard of care (control arm)
- Where
- Malawi
- Volunteers
- 130 people
- Sponsor
- University of North Carolina, Chapel Hill