Clinical trials: Drooling
Mastication Disorder
Effect of Functional Chewing Training on Tongue Thrust and Drooling in Children With Cerebral Palsy
This study examined the effect of Functional Chewing Training(FuCT) on tongue thrust and drooling in children with cerebral palsy.
- Trial name
- NCT03194048
- Testing
- Functional Chewing Training, Classical Oral Motor Exercises
- Volunteers
- 32 people
- Sponsor
- Hacettepe University
Executive Function (Cognition), Soccer Training
Cognitive-Integrated Soccer Training and Performance
This study will examine whether an 8-week soccer-specific cognitive-motor training program can improve executive functions, decision-making, and soccer skill performance in youth soccer players.
- Conditions
- Executive Function (Cognition), Soccer Training, Performance, Motor Development
- Trial name
- NCT07284940
- Testing
- Cognitively Engaging Soccer Practice, Conventional Soccer Practice
- Where
- China
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Fan Mao
Lower Urinary Tract Symptoms
Impact of Tadalafil 5 mg on Post-micturition Dribble in Young-age Men With no/Mild Lower Urinary Tract Symptoms
The primary objective of this prospective, single-centre randomized controlled trial is to assess the efficacy of tadalafil 5 mg on post-micturition dribble (PMD) in young age men (18-50 years) with no/mild lower urinary tract…
- Trial name
- NCT05146674
- Testing
- Tadalafil 5mg
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Mansoura University
Salivation in Parkinson's Disease
A Clinical Study of Dihydroergotine Mesylate Extended-release Tablets for the Treatment of Drooling in Parkinson's Disease.
Objective: To evaluate the efficacy and safety of dihydroergotine mesylate extended-release tablets for salivation in Parkinson\'s disease Study content: Using a randomized, double-blind, placebo-controlled study design, 120…
- Trial name
- NCT06319118
- Testing
- dihydroergotine mesylate sustained-release tablets
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Second Affiliated Hospital of Soochow University
Sialorrhea, Spastic Cerebral Palsy (sCP)
Effect of SCS Technique on Oromotor Skills in Children With CP
This study evaluates the clinical efficacy of the Strain Counter-Strain (SCS) technique on improving oromotor functions in children with spastic cerebral palsy.
- Conditions
- Sialorrhea, Spastic Cerebral Palsy (sCP), Strain Counterstrain Technique, Oral Motor Functions
- Trial name
- NCT07516860
- Testing
- Strain Counter-Strain (SCS), Designed Oral Motor Program
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Cairo University
Cerebral Palsy, Drooling
Validation of the French Version of the Drooling Impact Scale in a Pediatric Cerebral Palsy Population
The aim of this study is to present the French translation of the Drooling Impact Scale (DIS-F) and to explore its validity, reliability and responsiveness to change in a group of children with Cerebral Palsy (CP)
- Trial name
- NCT03986333
- Where
- 6 sites in France
- Volunteers
- 55 people
- Sponsor
- Centre Médico-Chirurgical de Réadaptation des Massues Croix Rouge Française
Sialorrhea, Cerebral Palsy
Application of Botulinum Toxin Type A in Salivary Glands in the Treatment of Drooling in Patients With Cerebral Palsy
The purpose of this study is to evaluate the safety and efficacy of botulinum toxin-A in salivary glands as a treatment for decrease drooling in patients with cerebral palsy and evaluate the long-term effects and tolerance .
- Trial name
- NCT01489904
- Testing
- BOTULINUM NEUROTOXIN TYPE-A
- Where
- Spain
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Hospital Vall d'Hebron
Adenocarcinoma of the Prostate
Pilot Study of DRibble Vaccine for Prostate Cancer Patients
This is a pilot study of the DRibble vaccine in patients with advanced prostate cancer.
- Trial name
- DRibble (NCT02234921)
- Testing
- Cyclophosphamide, DRibble Vaccine, HPV Vaccinations
- Where
- United States
- Volunteers
- 3 people
- Sponsor
- UbiVac
Hypersalivation, Cerebral Palsy
Turkish Validation of The Drooling Impact Scale
The aim of this study is to investigate the reliability and construct validity of the Turkish version of the Drooling Impact Scale in children with cerebral palsy
- Trial name
- NCT04132765
- Testing
- Drooling Impact Scale, Drooling Frequency and Severity Scale, The Caregiver Priorities and Child Health Index of Life with Disabilities (CPCHILD™)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Marmara University
Cerebral Palsy
Effects of Oral Motor Therapy in Children With Cerebral Palsy
: CP is a neurodevelopmental condition. A set of irreversible impairments of movement and posture development, resulting in activity limitation.
- Trial name
- NCT05792709
- Testing
- Oral Motor Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 10 people
- Sponsor
- Riphah International University
Cerebral Palsy
Evaluation of the Efficacy of the Injection of Botulinum Toxin A vs Scopolamine Patches in the Treatment of Drooling in Children With Cerebral Palsy
Cerebral palsy is the first cause of motor disability in developed countries. It is associated with altered motor function but also with mental, sensorial and behavior deficiencies.
- Trial name
- TOXSIALO (NCT03616067)
- Testing
- Botox® injection, Scopoderm® patches arm
- Where
- 11 sites in France
- Volunteers
- 23 people
- Sponsor
- Hospices Civils de Lyon
Autism Spectrum Disorder, Chewing Problem
Oral Structural and Functional Problems in Children With Autism
This study aims to examine oral structural and functional problems in children with autism.
- Conditions
- Autism Spectrum Disorder, Chewing Problem, Drooling
- Trial name
- NCT06355141
- Testing
- oral assessment
- Volunteers
- 90 people
- Sponsor
- Hacettepe University
Sialorrhea
Botulinum Toxin-A for Sialorrhoea Treatment in Asian Adults With Neurological Diseases
The efficacy of Botulinum toxin A (BoNT-A) in Asian population has not been properly studied and there is no literature available on the most efficacious dose of BoNT-A for sialorrhoea treatment.
- Trial name
- NCT02425176
- Testing
- Botulinum toxin A (BoNT-A) 50U, Botulinum toxin A (BoNT-A) 100U, Botulinum toxin A (BoNT-A) 200U
- Where
- Malaysia
- Volunteers
- 30 people
- Sponsor
- University of Malaya
Cerebral Palsy, Drooling
Treatment of Drooling With Type A Botulinum Toxin in Children With Cerebral Palsy
The purpose of this study is to evaluate the effectiveness of botulinum toxin injection to treat drooling in children with cerebral palsy, and to find the most appropriate dosage, duration of effect and side effects.
- Trial name
- NCT00173745
- Testing
- botulinum toxin A injection
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- National Taiwan University Hospital
Sialorrhea Secondary to Parkinson's Disease
Safety and Efficacy Study of NH004 Films for Relief of Sialorrhea Symptoms in Parkinson's Disease Patients
The primary goal of the study is to evaluate the safety and potential efficacy of intra-oral dissolvable NH004 films to improve the short-term symptoms of sialorrhea (drooling) in Parkinson's disease (PD) patients.
- Trial name
- NH004-2 (NCT00761137)
- Testing
- 0.3 mg tropicamide, 1 mg tropicamide, 3 mg tropicamide
- Where
- Argentina
- Volunteers
- 19 people
- Sponsor
- NeuroHealing Pharmaceuticals Inc.
Multiple Disabilities
Efficacy of Passive Oral Motor Therapy on Drooling in Children With Multiple Disabilities
This study was formulated to determine the efficacy of passive oral motor regimen for drooling in children with multiple disabilities. Seven subjects aged 7-19yrs were taken in the study.
- Trial name
- NCT02333981
- Testing
- passive oral motor therapy for drooling
- Volunteers
- 7 people
- Sponsor
- Maharishi Markendeswar University (Deemed to be University)
Drooling
A Multi-Center Study of MYOBLOC for the Treatment of Sialorrhea in Parkinson's Disease Patients
To determine safety, tolerability and preliminary efficacy of intraglandular injections of MYOBLOC for the treatment of sialorrhea in Parkinsons' Disease patients
- Trial name
- NCT00515437
- Testing
- Botulinum Toxin Type B (Myobloc)
- Where
- 18 sites in United States
- Volunteers
- 54 people
- Sponsor
- Solstice Neurosciences, LLC, a subsidiary of US WorldMeds, LLC
Hypersalivation, Prevention of Drooling
Efficacy of Intravenous Glyco-P® in Patients Undergoing Procedure That Require Anesthesia Service
This observational study was designed to prove clinical efficacy of the well known "glycopyrrolate" which is considered an orphan drug in Thailand.
- Conditions
- Hypersalivation, Prevention of Drooling, Bradycardia, Reversal of Muscle Relaxants
- Trial name
- NCT02102542
- Where
- Thailand
- Volunteers
- 65 people
- Sponsor
- Mahidol University
Cerebral Palsy (CP), Drooling
Effectiveness of Neuromuscular Electrical Stimulation Added to Oral Motor Therapy in Cerebral Palsy
This randomized, controlled, single-blind trial aims to investigate the effectiveness of neuromuscular electrical stimulation (NMES) combined with oral motor therapy in reducing drooling severity among children with cerebral…
- Trial name
- NOMES-CP (NCT07069257)
- Testing
- Oral Motor Therapy, Neuromuscular Electrical Stimulation (NMES)
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Aslinur Keles Ercisli, MD, PhD
Non Small Cell Lung Cancer
Autologous Tumor DRibble Vaccine in Patients With Non-Small Cell Lung Cancer
This is a pilot single institution study of DRibble vaccination + GM-CSF in patients with stage IIIB or IV NSCLC who have undergone 0-1 chemotherapy regimens for metastatic disease.
- Trial name
- DRibble (NCT00850785)
- Testing
- DRibble vaccine
- Where
- United States
- Volunteers
- 6 people
- Sponsor
- Providence Health & Services