Clinical trials: Drug Addiction
Substance-Related Disorders, Drug Addiction
Home-Based Program to Help Parents of Drug Abusing Adolescents
This project is aimed at parents with a teenager who is already starting to use drugs. The study will test a new, innovative version of a brief intervention.
- Conditions
- Substance-Related Disorders, Drug Addiction, Substance Abuse
- Trial name
- NCT01591239
- Testing
- Home-Based Intervention, Educational Group
- Where
- United States
- Volunteers
- 286 people, healthy volunteers welcome
- Sponsor
- Treatment Research Institute
Major Depression, Mania
Reliability and Validity of the MINI International Neuropsychiatric Interview for Children and Adolescents (MINI-KID)
The primary aims of this study are to assess: 1. The inter-rater and test-retest reliability of the MINI-KID 2. The validity of the standard MINI-KID interview in relation to the parent rated pencil/paper version (MINI-KID-P) and…
- Conditions
- Major Depression, Mania, Anxiety Disorders, Psychotic Disorder
- Trial name
- NCT00579267
- Testing
- MINI-KID
- Where
- United States
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Analgesic Drug Dependence, Sensory Disorders
Intrathecal Morphine Microdose Method Sensory Changes
Following the retrospective study on the effectiveness of the microdose method of intrathecal morphine therapy, the investigators are interested in measuring the sensory changes at 4 time points during the microdose method.
- Conditions
- Analgesic Drug Dependence, Sensory Disorders, Chronic Pain
- Trial name
- NCT03395275
- Testing
- Quantitative Sensory Tests, surveys
- Volunteers
- healthy volunteers welcome
- Sponsor
- The University of Texas Medical Branch, Galveston
Opiate Use Disorder
Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction
In this study, neuroimaging of reward processing, drug cue reactivity and inhibitory control is used before and immediately after 8 weeks of two types of group therapy in individuals with opioid addiction; clinical outcomes will…
- Trial name
- MORE (NCT04112186)
- Testing
- Behavioral group therapy #1, Behavioral group therapy #2
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Digital Technology, Technology Addiction
The Effect of Health Education Based Laughter Yoga Applied to Adolescents on Stress and Digital Gaming Habits
Adolescents may turn to digital games as a coping mechanism for stress, which can lead to addiction and various health problems.
- Conditions
- Digital Technology, Technology Addiction, Internet Addiction Disorder, Laughter Yoga
- Trial name
- Digital Habits (NCT07032090)
- Testing
- Health education, Laughter Yoga
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent)
An Opioid Prescribing Nudge
Analyze baseline concurrent opioid prescribing metrics at the individual prescriber level in the Duke Health System on the identified three main outcome measures.
- Conditions
- Opioid Use, Unspecified, Prescription Drug Abuse (Not Dependent), Prescription Drug Abuse and Dependency, Health Behavior
- Trial name
- OHS (NCT04069403)
- Testing
- Automated Reports on prescription patterns for their patients
- Where
- United States
- Volunteers
- 427 people, healthy volunteers welcome
- Sponsor
- Duke University
Alcohol Dependence, Veterans
Long-Acting Injectable Naltrexone Treatment of Alcohol Dependence in Primary Care vs. in Specialized Chemical Dependence Treatment: A Pilot Trial
The goal of the proposed project is to improve the primary care treatment of veterans with alcohol dependence. Alcohol dependence is a common behavioral health problem among veterans treated in VA primary care clinics.
- Trial name
- NCT00461890
- Testing
- Injectable Naltrexone
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- State University of New York - Upstate Medical University
Substance Use Disorders, Drug Use Disorder
Brief Contextual-Behavioral vs Twelve-Step Intervention for Emotion Regulation in Substance Use: Pilot Study
This study evaluated the effectiveness of a brief behavioral-contextual intervention delivered through 11 weekly individual sessions (45 minutes each) to improve emotion regulation, distress tolerance, and psychological…
- Conditions
- Substance Use Disorders, Drug Use Disorder, Alcohol Use Disorder, Emotional Dysregulation
- Trial name
- MEX-BERA (NCT07337733)
- Testing
- Behavioral-Contextual Emotion Regulation Program (BCERP)
- Where
- Mexico
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Lauro Gutiérrez Castro
Addiction, Alcohol
Substance Consumption, Personality, and Cognitive Functioning of Chess Players
The aim of this project is to find out if there is a difference in addictive behavior, personality traits, and cognitive abilities between chess players and non-chess players.
- Conditions
- Addiction, Alcohol, Nicotine, Drugs
- Trial name
- NCT06346353
- Where
- Germany
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Central Institute of Mental Health, Mannheim
Medication Overuse Headache
Orbitofrontal Cortex (OFC) Influence on Addictive Medication Overuse Headache (MOH) Deriving From Migraine
Medication Overuse Headache (MOH) is an illness affecting about 1,5 % of the general population. It is characterized by chronic headache occurring for at least 15 days a month, by a use of antimigraine drugs during at least 3…
- Trial name
- MOH-PET (NCT00833209)
- Testing
- PET (withdrawal), Imaging
- Where
- 2 sites in France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bordeaux
Drug Addiction, Vulnerability to Substance Addiction
Individual Differences in Reward and Impulse Control
Background: The risk for becoming addicted to drugs varies among individual, even those using similar drugs in a similar way. It is not known why some people become addicted and others do not.
- Trial name
- NCT01621607
- Where
- United States
- Volunteers
- 89 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Controlled Drug Dependence
Evaluation of the Effectiveness of a Continuing Education Program in Community Pharmacies
Preventable failures in the drug chain are related to Drugs Problems Related Use and are associated with medication errors (prescription, dispensing, administration or use by the patient or caregiver), including failures In the…
- Trial name
- NCT03388567
- Testing
- Staff pharmacy whith intervention
- Where
- Colombia
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Universidad de Antioquia
Addiction
Leveraging Technology to Address Unhealthy Drug Use in Primary Care Settings
This study will develop a clinical decision support tool that assists primary care providers in carrying out substance use interventions, and then compare (in Phase 2) two clinical scenarios, screening only (SO) vs.
- Trial name
- NCT02893514
- Testing
- Screening Only (SO) condition, SUSIT Condition
- Where
- United States
- Volunteers
- 79 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Substance-Related Disorders, Drug Addiction
Family Training Program for Parents of Substance Using Adolescents
This project will modify Community Reinforcement and Family Training (CRAFT; n=15) and Alanon/Naranon Facilitation (ANF; n=15) for use with parents who are concerned about an out-of-treatment adolescent.
- Conditions
- Substance-Related Disorders, Drug Addiction, Substance Abuse
- Trial name
- FTP (NCT01344382)
- Testing
- Community Reinforcement and Family Training, Al-Anon Facilitation
- Where
- United States
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Treatment Research Institute
Substance Use Disorder (SUD), Alcohol Use Disorder (AUD)
Metabolome and Gut Microbiome Changes During Smoking Cessation in Long-term Drug Therapy in a Therapeutic Community
Theoretical Framework: Cigarette smoking is the leading preventable cause of death worldwide, with nicotine dependence notably common among individuals with Substance Use Disorders (SUD).
- Conditions
- Substance Use Disorder (SUD), Alcohol Use Disorder (AUD), Nicotine Addiction, Healthy Adult Participants
- Trial name
- NCT06803706
- Testing
- 6-weeks CBT smoking cessation programme, Long-term drug therapy within a therapeutic community
- Where
- 3 sites in Austria
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- Sigmund Freud PrivatUniversitat
Insomnia, Quality of Life
Auricular Acupuncture and Cognitive Behavioral Therapy Treatment for Insomnia
"Auricular acupuncture and cognitive behavioral therapy in the context of insomnia and low dose dependence of benzodiazepine-like drugs and other sleep medicine with addiction risk" INTRODUCTION: Insomnia is a common health…
- Trial name
- NADA (NCT01765959)
- Testing
- Auricular acupuncture (AA), cognitive behavioral therapy (CBT)
- Where
- Sweden
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Substance-Related Disorders
Brief Intervention in Primary Care for Problem Drug Use and Abuse
This study will examine the effectiveness of a brief intervention in a primary care setting to reduce drug use or abuse compared to enhanced care as usual.
- Trial name
- NCT00877331
- Testing
- Brief intervention using motivational interviewing
- Where
- United States
- Volunteers
- 868 people, healthy volunteers welcome
- Sponsor
- University of Washington
Drug Misuse, Addiction
Construction of a Risk Screening Tool for New Psychoactive Substance Misuse Among Adolescents and Young Adults
The goal of this observational study is to construct a risk tool available for screening young adults and adolescents at high risk of drug misuse and provides a chance for early intervention to young adults and adolescents at…
- Trial name
- NCT06714578
- Testing
- Questionnaire and Physical Exam
- Where
- China
- Volunteers
- 1,035 people, healthy volunteers welcome
- Sponsor
- Wei XIA, PhD
Drug Addiction
The Cognitive Neural Mechanisms and Neuroregulatory Interventions of Realistic Creative Problem-solving Under the Effects of Drug Addiction
Drug addiction persists as a significant global social concern with a negative impact on social harmony and stability that cannot be ignored.
- Trial name
- NCT06917534
- Testing
- Transcranial direct current stimulation
- Where
- China
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Yifan Wang
Internet Addiction Disorder, Health Promotion
The Effect of Health Education on Digital Game Addiction and Health Promotion Behavior in Adolescents
This study aimed to evaluate the effectiveness of a school nurse-led health education program in reducing digital game addiction and improving health-promoting behaviors among adolescents.
- Conditions
- Internet Addiction Disorder, Health Promotion, Digital Game Addiction, Adolescent
- Trial name
- NCT07002515
- Testing
- Health Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi