Clinical trials: Drug Distribution
Sedentary Behavior, Overweight
The Project ATA: Adipose Tissue & Adipokines
It is essential to delve deeper into the molecular and tissue aspects that allow us to recognize the roles of adipose tissue and its interaction with the musculoskeletal (i.e., adipomyokines) to facilitate the identification of…
- Conditions
- Sedentary Behavior, Overweight, Obesity
- Trial name
- ATA (NCT05758311)
- Where
- Colombia
- Volunteers
- 378 people, healthy volunteers welcome
- Sponsor
- Dynamical Business and Science Society - DBSS International SAS
Sepsis, Severe Infection
Evaluation of Monocyte Volume Distribution Width (MDW) for Early Detection of Sepsis
The measurement of monocyte volume width distribution (MDW) is intended for use with adult patients presenting to the emergency department (ED), where a CBC with Differential has been ordered, as an aid in the early detection of…
- Trial name
- MDW (NCT03145428)
- Testing
- CBC-Diff Monocyte volume width distribution (MDW)
- Where
- 3 sites in United States
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Beckman Coulter, Inc.
Overfeeding
Polyphenols and Overfeeding
Obesity is a complex and multifactorial disease representing a major public health challenge. Indeed, overweight and obese people carry a major risk of developing insulin resistance and type 2 diabetes mellitus.
- Trial name
- Poly-Nut (NCT02145780)
- Testing
- 2g of grape polyphenol extract
- Where
- France
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospices Civils de Lyon
Healthy
A Study to Investigate the Whole Body Distribution and Radiation Dosimetry of the Positron Emission Tomography Ligand Fluoride-18 (18F)-JNJ-64326067 in Healthy Participants
The purpose of this study is to measure the whole-body distribution and radiation dosimetry of 18F-JNJ-64326067 in healthy participants.
- Trial name
- NCT03581916
- Testing
- 18F-JNJ-64326067
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
HIV
Combination Partner HIV Testing Strategies for HIV-positive and HIV-negative Pregnant Women
The overall objective of this study is to evaluate whether the addition of secondary distribution HIV self-test kits to existing partner notification guidelines increases the proportion of male partners who access facility-based…
- Trial name
- MP3 Pilot (NCT04124536)
- Testing
- HIV self-testing with partner notification.
- Where
- Zambia
- Volunteers
- 341 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Healthy, Parkinson Disease
PET Study of the Nicotinic Receptors in Human
The purpose of this study is to quantify the brain distribution of the nicotinic receptors in human volunteers and their alterations in patients suffering from neurological diseases such as Parkinson and Alzheimer diseases and…
- Conditions
- Healthy, Parkinson Disease, Alzheimer Disease, Epilepsy
- Trial name
- NCT00543322
- Where
- France
- Volunteers
- healthy volunteers welcome
- Sponsor
- Commissariat A L'energie Atomique
Postprandial Lipemia, Postprandial Glycemia
Exploring the Effects of Varying Fat:Carbohydrate Diet Permutations on Gastric Emptying and Metabolic Status Using Human Postprandial Model
The aim of this clinical trial is to investigate the effects of the meals moderated by fat and carbohydrate (CHO) quality along with varying macronutrient distribution (CHO: fat) on gut physiology and metabolic outcomes using the…
- Conditions
- Postprandial Lipemia, Postprandial Glycemia, Gastric Emptying
- Trial name
- NCT05977244
- Testing
- FIJA, F1JB, F2JA
- Where
- 3 sites in Malaysia
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Malaysia Palm Oil Board
Healthy
A Study to Examine the Distribution of PF-06372865 in the Brain of Healthy Volunteers Using Positron Emission Tomography and a Radioactive Tracer Following Oral Administration of One Dose of PF-06372865
This study will see how PF-06372865, an experimental drug distributes in the brain after one dose of PF-06372865 is administered orally to healthy volunteer subjects.
- Trial name
- NCT02138500
- Testing
- PF-06372865
- Where
- 3 sites in United States
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy
Effectiveness of Metaverse Space-based Exercise Video Distribution in Young Adults
This study explored whether exercise video distribution using metaverse space is effective in increasing physical activity among young people, along with mental health and locomotive function.
- Trial name
- NCT06019156
- Testing
- Exercise video distribution of Metaverse, Exercise video distribution of YouTube
- Where
- Japan
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Hiroshima University
Lumbar Disc Herniation
Exploring the Distribution Patterns and Infrared Characteristics of Force-sensitive Acupoints in Different Lumbar Nerve Segments in Patients With LDH Based on "Press Quickly" Theory
Utilizing the "responsive acupoint palpation" technique and infrared thermography, we investigated the distribution patterns of pressure-sensitive acupoints across different lumbar spinal segments in patients with lumbar disc…
- Trial name
- NCT06318156
- Testing
- Infrared thermal imaging
- Where
- China
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Zhou Xingchen
Pulmonary Disease, Chronic Obstructive
Evaluation of the Lung Deposition Rate and Distribution Pattern of Tiotropium Via HandiHalerTM in Healthy Subjects and Patients With Chronic Obstructive Pulmonary Disease (COPD)
Primary endpoint: whole lung deposition and in-vivo distribution pattern of a 99mTc-labelled tiotropium powder formulation following inhalation via HandiHalerTM in healthy subjects as well as in patients with mild, moderate and…
- Trial name
- NCT02172456
- Testing
- 99mTc-radiolabelled tiotropium, non-radiolabelled tiotropium
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy Adult Male
Acute Effects of Caffeine on Repeated Sprint Performance and Energy Distribution
The goal of this study is to learn if low-dose caffeinated coffee improves repeated sprint performance and affects energy system contributions in combat sports athletes.
- Trial name
- NCT07596511
- Testing
- Cycling Repeated Sprint Test (6 × 10 s), Breath-by-Breath VO₂ Monitoring - COSMED K5, Capillary Blood Lactate Sampling (non-invasive)
- Where
- Turkey (Türkiye)
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Trabzon University
Red Blood Cell Health, Biological Aging
Effect of Pentadecanoic Acid Supplementation on Red Blood Cell Health and Biological Aging in Healthy Older Adults
This Phase II randomized, double-blind, placebo-controlled, parallel-group study will evaluate the effects of pentadecanoic acid (C15:0) supplementation on red blood cell (RBC) health and predicted biological age in healthy…
- Conditions
- Red Blood Cell Health, Biological Aging, Healthy Aging
- Trial name
- NCT07812792
- Testing
- Pentadecanoic Acid
- Where
- Canada
- Volunteers
- 93 people, healthy volunteers welcome
- Sponsor
- ReCellience15, Inc
Healthy
Procalcitonin Test Reference Range Determination
Prospective, single-centre study in healthy volunteers to establish a reference range for the RAMP Procalcitonin (PCT) test. The primary objective of this study is to establish the reference range for measurement of PCT levels…
- Trial name
- PRO-H (NCT02591121)
- Where
- Canada
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Response Biomedical Corp.
Healthy Volunteers, Foot Biomechanics
Effects of Daily Footwear Use on Lower Extremity Health and Movement in Healthy Adults
Footwear is one of the most important external factors influencing lower extremity biomechanics, plantar sensory feedback, and postural control.
- Trial name
- NCT07735949
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Obesity, Metabolic Disease
Body Fat Distribution and Fat Metabolism
The primary purpose of the study is to examine the effect of body fat distribution on the physiological response to a dietary fat intervention.
- Trial name
- NCT00475774
- Testing
- Long-chain (C18:2) and medium chain fatty acid (C8 and C10).
- Where
- Netherlands
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- TNO
Healthy Participants
The Influence of Posture on Airway Diameter, Resistance and Airflow Distribution in Healthy Subjects
FRI could give the opportunity to investigate the possible effect of a lateral posture on airway diameter and airflow distributions.
- Trial name
- NCT01893697
- Testing
- HRCT scan in a specific postural position
- Where
- Belgium
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- University Hospital, Antwerp
Healthy
A Study To Examine The Distribution Of PF-05212377 In The Brain Of Healthy Volunteer Subjects Using Positron Emission Tomography And A Radioactive Tracer Following Oral Administration Of One Dose Of PF-05212377
This study will see how PF-05212377, an experimental drug to treat symptoms from Alzheimer's Disease, distributes in the brain after one dose of PF-05212377 is administered orally to healthy volunteer subjects.
- Trial name
- NCT02005991
- Testing
- PF-05212377
- Where
- 3 sites in United States
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Pfizer
Healthy, Psoriasis
Distribution of Secukinumab (AIN457) Into Dermal Interstitial Fluid After a Single Subcutaneous Administration of 300 mg
The proposed exploratory study aims to understand the in vivo skin distribution properties of subcutaneously (s.c.) administered AIN457 in psoriatic and healthy skin using open flow microperfusion (OFM).
- Trial name
- OFM ISF (NCT01539213)
- Testing
- secukinumab (AIN457)
- Where
- Austria
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals
HIV Seropositivity
Community-based Distribution of Oral HIV Self-testing Kits
This cluster randomised trial aims to evaluate the impact of a pilot HIVST intervention of oral HIV self-testing (HIVST) as an option for HIV testing, in addition to the offer of home-based rapid HIV testing, through community…
- Trial name
- NCT02994329
- Testing
- OraQuick® HIV Self-Test (Orasure Technologies, Thailand)
- Where
- Zambia
- Volunteers
- 8,080 people, healthy volunteers welcome
- Sponsor
- Zambart