Clinical trials: Drug Eluting Stents
Coronary Artery Disease
Tailored Anti-platelet Therapy After DES Implantation in High-risk Patients
Clopidogrel monotherapy has been found effective in reducing ischaemic cardiovascular and haemorrhagic complications in patients with drug-eluting stent (DES) placement.
- Trial name
- NCT05936606
- Testing
- Clopidogrel monotherapy, Tailored anti-platelet therapy
- Where
- South Korea
- Volunteers
- 3,434 people
- Sponsor
- Yonsei University
Biliary Stricture, Malignant Neoplasms
Patency and Safety of the Drug Eluting Covered Biliary Stent Comparing to the Common Covered Biliary Stent
Paclitaxel covered metal biliary stent extents their patency rate comparing to the Common Covered Metallic Biliary Stent.
- Trial name
- MIRA-cover (NCT01512563)
- Testing
- Biliary stent
- Where
- 3 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- Taewoong Medical Co., Ltd.
Coronary Disease, Coronary Artery Disease
Safety and Efficacy of the ZoMaxx™ Drug-Eluting Stent System in Coronary Arteries
The purpose of this study is to demonstrate the safety and efficacy of the ZoMaxx drug-eluting stent in patients with blockage of native coronary arteries.
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- ZoMaxx™ I (NCT00148356)
- Testing
- ZoMaxx™ Drug-Eluting Coronary Stent System, TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent System
- Where
- 29 sites in Australia, Belgium and 8 more
- Volunteers
- 401 people
- Sponsor
- Abbott Medical Devices
Ischemic Stroke, Vertebral Artery Stenosis
Drug-eluting Stenting Versus Medical Treatment for Extracranial Vertebral Artery Stenosis
Posterior circulation stroke accounts for 20% of all ischemic stroke. Approximately one quarter of posterior circulation strokes are due to stenosis in the vertebral artery and basilar artery.
- Trial name
- VISTA (NCT05885932)
- Testing
- Drug-eluting stenting plus aspirin and clopidogrel or ticagrelor, Aspirin and clopidogrel or ticagrelor, mono anti-platelet therapy
- Where
- China
- Volunteers
- 472 people
- Sponsor
- Xuanwu Hospital, Beijing
Drug-coated Balloon, Drug-eluting Stent
STrategies of Scheduled Drug-coated Balloons (DCB) Versus Conventional DES for the interveNTional Therapy of de Novo Lesions in Large Coronary vESSels (STENTLESS) Trial
This is a multicenter, open-label, randomized controlled study meant to compare the safety and efficacy of scheduled drug-coated balloon (DCB) and conventional drug-eluting stent (DES) strategy in the treatment of de novo lesions…
- Conditions
- Drug-coated Balloon, Drug-eluting Stent, De Novo Stenosis
- Trial name
- STENTLESS (NCT06084000)
- Testing
- Drug-coated balloon (Commercially available Paclitaxel-coated Balloon, China), Drug-eluting stent
- Where
- China
- Volunteers
- 2,700 people
- Sponsor
- China National Center for Cardiovascular Diseases
ICAD - Intracranial Atherosclerotic Disease, ICAS - Intracranial Atherosclerosis
Drug Eluting Stenting and Aggressive Medical Treatment for Preventing Recurrent Stroke in Intracranial Atherosclerotic Disease Trial
The aim of DREAM-PRIDE is to evaluate whether implantation of drug-eluting stent (DES) combined with aggressive medical treatment is more efficacious in prevention of 1-year stroke recurrence than standard medical treatment alone…
- Conditions
- ICAD - Intracranial Atherosclerotic Disease, ICAS - Intracranial Atherosclerosis, Drug-eluting Stent, Stroke
- Trial name
- DREAM-PRIDE (NCT04948749)
- Testing
- Drug Eluting Stent implantation, Aggressive medical treatment, Risk factor management
- Where
- 18 sites in China
- Volunteers
- 358 people
- Sponsor
- Beijing Tiantan Hospital
Coronary Artery Disease
Registry to Evaluate the Efficacy of Zotarolimus-Eluting Stent
The objective of this study is to evaluate the safety and long-term effectiveness of coronary stenting with the zotarolimus eluting stent (ZES) and to determine clinical device and procedural success during commercial use of ZES.
- Trial name
- NCT00960908
- Testing
- Endeavor Resolute stents, Endeavor Sprint stent
- Where
- 19 sites in South Korea
- Volunteers
- 4,000 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Drug-coated Balloons Versus Drug-eluting Stents for de Novo Small-vessel Coronary Artery Disease
This prospective, multicenter observational study will compare the safety and clinical outcomes of drug-coated balloon angioplasty and second-generation drug-eluting stent implantation in patients undergoing percutaneous coronary…
- Trial name
- DCB-SVD (NCT07839806)
- Testing
- Drug coated balloon, Drug Eluting stent
- Where
- Greece
- Volunteers
- 230 people
- Sponsor
- National and Kapodistrian University of Athens
Coronary Disease
Prognostic Implications of Physiologic Investigation After Revascularization With Stent
Percutaneous coronary intervention (PCI) is a standard treatment strategy for coronary artery disease (CAD). With the presence of myocardial ischemia, PCI reduces the risks of death, myocardial infarction (MI) and…
- Trial name
- POST-PCI FLOW (NCT04684043)
- Testing
- Percutaneous coronary intervention
- Where
- South Korea
- Volunteers
- 5,100 people
- Sponsor
- Bon-Kwon Koo
Coronary Artery Disease
DynamX Bioadaptor Hong Kong Registry
Prospective, non-randomized, multicenter registry
- Trial name
- NCT04483791
- Testing
- DynamX Novolimus Eluting Coronary Bioadaptor System
- Where
- 4 sites in China
- Volunteers
- 50 people
- Sponsor
- Elixir Medical Corporation
Coronary Arteriosclerosis, Angina Unstable
Stents, Drug Eluting Stents, and CABG- Financial and Clinical Impact.
Options for coronary revascularization include stent implantation and coronary bypass surgery. Both modalities have their unique advantages and disadvantages in terms of clinical outcomes as well as financial impact on the…
- Conditions
- Coronary Arteriosclerosis, Angina Unstable, Myocardial Infarction
- Trial name
- NCT00394680
- Volunteers
- 700 people
- Sponsor
- Shaare Zedek Medical Center
Acute Myocardial Infarction
Drug Eluting Stent (DES) in Primary Angioplasty
Stent implantation is the best treatment in patients with acute myocardial infarction (STEMI) referred for primary angioplasty (pPCI).
- Trial name
- PASEO (NCT00759850)
- Testing
- Drug Eluting Stent (DES)
- Where
- Italy
- Volunteers
- 270 people
- Sponsor
- San Giuseppe Moscati Hospital
Stable Angina
Evaluation of Vascular Regeneration After a Drug Eluting Stent Implantation
This is a prospective cohort, one center. twenty patients who will undergo percutaneous stent implantation with everolimus eluting stent will be include. The primary endpoint was the correlation between the change (baseline vs.
- Trial name
- REVER (NCT03214900)
- Volunteers
- 20 people
- Sponsor
- Hospital San Carlos, Madrid
Emphysema
EASE Trial: Exhale Airway Stents for Emphysema
This is an international clinical research study evaluating the safety and effectiveness of a new procedure called airway bypass.
- Trial name
- EASE (NCT00391612)
- Testing
- Exhale® Drug-Eluting Stent
- Where
- 37 sites in United States, Australia and 8 more
- Volunteers
- 450 people
- Sponsor
- Broncus Technologies
Renal Calculi, Ureteral Obstruction
Assessment of Drug-eluting Ureteral Stent on Bacterial Adherence and Biofilm Formation
The purpose of this study is to determine the clinical effects of a triclosan stent on adherent bacteria, stent biofilms, and patient urine cultures in patients with an indwelling triclosan ureteral stent.
- Trial name
- NCT00250406
- Testing
- Ureteral Stent
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-VIII All-comers Orsiro Mission Safety and Performance Registry
The BIOFLOW-VIII registry is a post-market clinical evaluation of the Orsiro Mission stent in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- BIOFLOW-VIII (NCT04555174)
- Testing
- Orsiro Mission DES
- Where
- 41 sites in France
- Volunteers
- 872 people
- Sponsor
- Biotronik AG
Coronary Artery Disease
Optical Coherence Tomography in Long Lesions
Increasing lesion complexity in percutaneous coronary interventions (PCI) has warranted the use of overlapping drug-eluting stents.
- Trial name
- LONG OCT (NCT01133925)
- Testing
- Resolute Sprint, Sirolimus Eluting Stent, Paclitaxel Eluting Stent
- Where
- Italy
- Volunteers
- 22 people
- Sponsor
- A.O. Ospedale Papa Giovanni XXIII
Coronary Artery Disease
Clinical Management of Antiplatelet Drug Resistance in Patients With Drug Eluting Coronary Stents
It is recommended that patients who have drug-eluting stents placed in their coronary arteries take aspirin and Plavix (Clopidogrel) for at least a year.
- Trial name
- NCT00589862
- Testing
- Plavix (Clopidogrel)
- Where
- United States
- Sponsor
- Creighton University
Acute ST Segment Elevation Myocardial Infarction
Performance of Bioresorbable Scaffold in Primary Percutaneous Intervention of ST Elevation Myocardial Infarct
Patients presenting with acute ST elevation myocardial infarct urgently need revascularization. Standard of care is establishing bloodflow through the coronary vessels using thrombus aspiration catheter, and securing the result…
- Trial name
- BVS in STEMI (NCT02067091)
- Testing
- stent implant in a coronary artery
- Where
- 2 sites in Denmark, Norway
- Volunteers
- 120 people
- Sponsor
- Haukeland University Hospital
Peripheral Artery Disease
Evaluating the Safety and Efficacy of the G-stream® Drug-Eluting Stent in the Above-the-Knee Femoropopliteal Artery
A multicenter, randomized, controlled, superiority clinical trial to evaluate the efficacy and safety of drug-eluting peripheral arterial stent system（G-stream） in the treatment of femoropopliteal artery stenosis or occlusion.
- Trial name
- G-streamPAD (NCT05780359)
- Testing
- Drug eluting stent, drug coating balloon
- Where
- China
- Volunteers
- 280 people
- Sponsor
- Shenzhen Salubris Pharmaceuticals Co., Ltd.