Clinical trials: Drug Eluting Stents
Coronary Artery Disease, Ischemic Heart Disease
Cortisone or Drug Eluting Stents (DES) as Compared to Bare Metal Stents (BMS) to EliminAte Restenosis
The possibility of using the new drug eluting stents (DES) technology has significantly changed the mid-term outcome of percutaneous coronary interventions (PCI) in terms of reduced recurrence of angina.
- Conditions
- Coronary Artery Disease, Ischemic Heart Disease, Atherosclerosis
- Trial name
- NCT00369356
- Testing
- Prednisone, Drug eluting coronary stent, Bare metal coronary stent
- Where
- 5 sites in Italy
- Volunteers
- 375 people
- Sponsor
- Universita di Verona
Acute Coronary Syndrome
Polymer Free Stent in Acute Coronary Syndrome
To evaluate the short term out comes of the polymer free stents in patients presented with non ST elevation acute coronary syndrome (which include ST depression myocardial infarction and unstable angina ) after percutaneous…
- Trial name
- NCT03878966
- Testing
- Inserting polymer free drug eluting stent in the coronary arteries
- Volunteers
- 30 people
- Sponsor
- Assiut University
Stable Angina, Unstable Angina
Harmonizing Optimal Strategy for Treatment of Coronary Artery Stenosis - Coronary Intervention With Next Generation Drug-Eluting Stent Platforms and Abbreviated Dual Antiplatelet Therapy (HOST-IDEA) Trial
We had little experience in coronary intervention with recently introduced newer drug-eluting stent (DES) platforms, despite great anticipation, and optimal duration of dual antiplatelet therapy (DAPT) for these stent systems…
- Conditions
- Stable Angina, Unstable Angina, Non-ST Segment Elevation Myocardial Infarction
- Trial name
- HOST-IDEA (NCT02601157)
- Testing
- 3-months DAPT, 1-year DAPT
- Where
- 12 sites in South Korea
- Volunteers
- 2,173 people
- Sponsor
- Seoul National University Hospital
Coronary Disease, Heart Diseases
Clinical Efficacy of Stent-balloon-stent (SBS) Technique in the Treatment of Coronary Bifurcation Lesions
The treatment of coronary bifurcation lesions continue to remain challenges. Due to the special hemodynamics caused by the special anatomical structure of the coronary bifurcation, it is easy to cause vascular crest displacement…
- Conditions
- Coronary Disease, Heart Diseases, Cardiovascular Diseases, Vascular Diseases
- Trial name
- NCT06045039
- Testing
- Stent-balloon-stent (SBS) technique
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Henan Institute of Cardiovascular Epidemiology
Biliary Neoplasms, Biliary Obstruction
Comparison of Drug Eluting Stent and Covered Metal Stent in Malignant Biliary Obstruction (MIRA III)
The purpose of this study is to compare the effectiveness and safety of Niti-S Mira-Cover III Biliary Stent with Comvi Biliary Covered Stent for the treatment of malignant biliary obstruction.
- Conditions
- Biliary Neoplasms, Biliary Obstruction, Pancreatic Neoplasms
- Trial name
- NCT02460432
- Testing
- Paclitaxel-eluting metal Stent, Covered Metal Stent
- Where
- 5 sites in South Korea
- Volunteers
- 106 people
- Sponsor
- Taewoong Medical Co., Ltd.
Acute ST-elevation Myocardial Infarction
the Effect of Prolonged Inflation Time During Stents Deployment for ST-elevation Myocardial Infarction
The purpose of this study is to determine whether prolonged inflation time on drug-eluting stents deployment for ST-elevation myocardial Infarction was better than conventional stents deployment.
- Trial name
- NCT03199014
- Testing
- deploying the Drug-eluting Stents with a prolonged time, deploying the Drug-eluting Stents with a conventional time
- Where
- China
- Volunteers
- 60 people
- Sponsor
- West China Hospital
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Austria Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667016
- Where
- 8 sites in Austria
- Volunteers
- 305 people
- Sponsor
- Biotronik Vertriebs-GmbH
Coronary Artery Disease
Vascular Response of Orsiro vs. Xience Drug-Eluting Stents for Treating Coronary Bifurcation Lesions
This study aims to compare vessel response and clinical outcomes of a biodegradable-polymer, ultra-thin strut, drug-eluting stent (Orsiro, Biotronik) and a durable-polymer, thin-strut, drug-eluting stent (Xience, Abbott) for the…
- Trial name
- NCT05200637
- Testing
- Orsiro stent, Xience stent, Any drug-eluting stent
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- Chang Gung Memorial Hospital
Drug-Eluting Stents, Percutaneous Coronary Intervention
Firehawk™ Coronary Stent System in the Treatment of Coronary Chronic Total Occlusion Lesion(s)
This study is a prospective, multi-center, open-label, randomized controlled clinical trial,aims to assess the safety and effectiveness of the Firehawk™ sirolimus target-eluting coronary stent system with abluminal grooves…
- Conditions
- Drug-Eluting Stents, Percutaneous Coronary Intervention, Tomography, Optical Coherence
- Trial name
- NCT03040934
- Testing
- Firehawk sirolimus target eluting coronary stent system, XIENCE Everolimus-Eluting Coronary Stent System
- Where
- China
- Volunteers
- 196 people
- Sponsor
- Shanghai MicroPort Medical (Group) Co., Ltd.
Ischemic Stroke, Vertebral Artery Stenosis
Drug Eluting Stents Versus Bare Metal Stents for Treatment of Symptomatic Extracranial Vertebral Artery Stenosis
Stroke is one of the important causes of disability and death in the world, in which more than half were ischemic strokes. About 1/4 of the ischemic stroke occurred in the vertebral basilar artery system, especially when in the…
- Trial name
- NCT03201432
- Testing
- Drug eluting stent (DES), Bare metal stent (BES)
- Volunteers
- 160 people
- Sponsor
- Xiongjing Jiang
Coronary Artery Disease
A Study to Evaluate the Efficacy and Safety of BuMA Supreme Drug Eluting Stent(DES)
PIONEER-II RCT trial is a prospective, multicenter, randomized, non-inferiority registry trial. 539 subjects from about 40 interventional cardiology centers in China will be enrolled to evaluate In-stent late lumen loss(LLL) as…
- Trial name
- RCT (NCT02698839)
- Testing
- BuMA Supreme, BuMA™
- Where
- China
- Volunteers
- 539 people
- Sponsor
- Sino Medical Sciences Technology Inc.
Coronary Artery Stenosis
Angiography Study of BioNIR Drug Eluting Stent System (NIREUS)
The NIREUS study aims to demonstrate angiographic non-inferiority for the BioNIR Ridaforolimus Eluting Coronary Stent System (hereafter referred to as BioNIR) in comparison to the Resolute zotarolimus-eluting stent (hereafter…
- Trial name
- NIREUS (NCT01995500)
- Testing
- BioNIR, Resolute
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Medinol Ltd.
In-Stent Restenosis
Treatment of Drug-eluting Stent (DES) In-Stent Restenosis With SeQuent® Please Paclitaxel Eluting Percutaneous Transluminal Coronary Angioplasty (PTCA) Catheter
The aim of the study is to assess the efficacy of the Paclitaxel-eluting PTCA - balloon catheter SeQuent® Please to treat in-stent restenoses (ISR) of various drug eluting stents in native coronary arteries with reference…
- Trial name
- NCT00998439
- Testing
- SeQuent® Please, SeQuent® II
- Where
- 8 sites in Germany
- Volunteers
- 120 people
- Sponsor
- Klinikum Coburg
Coronary Artery Disease, Acute Coronary Syndrome
A Comparison of an Ultrathin Strut Biodegradable Polymer Sirolimus-Eluting Stent With a Durable Polymer Everolimus-Eluting Stent for Patients With Acute ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention
PCI is considered as the reperfusion strategy of choice for patients with acute STEMI. Data from RCTs and meta-analyses demonstrate a consistent and strong signal towards a significant reduction in MACE among patients with STEMI…
- Trial name
- BIOSTEMI (NCT02579031)
- Testing
- Orsiro, Xience
- Where
- 10 sites in Switzerland
- Volunteers
- 1,300 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Implant
Post-dilatation for Optimization of Drug-eluting Stents (DES) Deployment Assessed by Intravascular Ultrasound Multicenter Analysis
Comparison with use of Intravascular Ultrasound (IVUS) analysis of two methods of percutaneous coronary interventions (PCI) with drug eluting stent: After successful drug eluting stent implantation, patients were randomized into…
- Trial name
- PODIUM (NCT01103765)
- Testing
- post dilatation after stent deployment, stent deployment without post-dilatation
- Where
- France
- Volunteers
- 220 people
- Sponsor
- Recherches et etudes en sciences sociales et sante, France
Device Related MACE and Bleeding
e-BioMatrix Canada Registry
Prospective, multi-center registry to be conducted at 6 Canadian interventional cardiology centers. The e-BioMatrix data will be compared with a historical control group, the Cypher arm of the Biosensors Leaders study consisting…
- Trial name
- NCT01915628
- Testing
- BioMatrix Flex
- Where
- 4 sites in Canada
- Volunteers
- 535 people
- Sponsor
- Biosensors Europe SA
Coronary Artery Disease, Antineoplastic Agents
Bioheart Rapamycin Drug-Eluting Bioresorbable Coronary Stent System Clinical Study
The Bioheart Randomized Controlled Trial is a prospective multicentred paralleled study, which will enroll 430 patients and randomized 1:1 to study group and control group.
- Trial name
- NCT03284255
- Testing
- study group, control group
- Where
- 25 sites in China
- Volunteers
- 431 people
- Sponsor
- Shanghai Bio-heart Biological Technology Co., Ltd.
Ischemic Heart Disease, Coronary Atherosclerosis
Sirolimus-eluting Stent CALYPSO vs Everolimus-eluting Stent XIENCE
The aim of the study is to evaluate the efficacy and safety of sirolimus-eluting coronary stent "Calypso" (Angioline, Russia) in comparison with everolimus-eluting coronary stent "Xience" (Abbott Vascular, USA)
- Conditions
- Ischemic Heart Disease, Coronary Atherosclerosis, Coronary Artery Disease, Coronary Artery Stenosis
- Trial name
- PATRIOT (NCT02681016)
- Testing
- DES "Calypso", DES "Xience Prime", Coronary angioplasty
- Where
- Russia
- Volunteers
- 610 people
- Sponsor
- Meshalkin Research Institute of Pathology of Circulation
Chronic Kidney Diseases
Appropriate Duration of Anti-Platelet straTegy in Patients With Advance Chronic Kidney Disease After New Generation Drug Eluting Stents (ADAPT-CKD)
The purpose of this prospective randomized clinical trial is to compare the clinical outcomes according to the duration of aspirin and clopidogrel or prasugrel with dual anti-platelet therapy after percutaneous coronary…
- Trial name
- NCT04708587
- Testing
- dual anti-platelet therapy at least 6 months, dual anti-platelet therapy 3months or less
- Where
- South Korea
- Volunteers
- 900 people
- Sponsor
- Yonsei University
De Novo Stenosis, Coronary Artery Disease
Bioresorbable Sirolimus-eluting scaffold in de Novo Coronary Artery Lesions
Bioresorbable scaffold (BRS) was designed aiming to avoid the late adverse events associated with permanent metallic stents by providing temporary support to the vessel wall and promoting vessel remodeling, plaque reduction, and…
- Trial name
- REC-CAGEFREE Ⅳ (NCT07022587)
- Testing
- Sirolimus-eluting bioresorbable scaffolds, Sirolimus-eluting stents
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Xijing Hospital