Clinical trials: Drug Use
Knowledge, Attitudes, Practice
Determinants of Knowledge About and Use of Dietary Supplements
This study aims to evaluate (1) the level of knowledge about dietary supplements (KaDS) among people potentially interested in health issues in Poland and (2) the fraction of these people using dietary supplements (UoDS).
- Trial name
- NCT04184219
- Where
- Poland
- Volunteers
- 7,632 people, healthy volunteers welcome
- Sponsor
- Medical University of Lodz
Mood Disturbance, Mood Change
Mood and Cognitive Effects of Psilocybin in Healthy Participants
This study is seeking to find the optimal microdose or low dose of psilocybin (magic mushrooms) that provides general enhancements to mood, memory, sleep, and other measures of general well-being without any hallucinogenic…
- Conditions
- Mood Disturbance, Mood Change, Sleep Disturbance, Drug Effect
- Trial name
- MELO (NCT05252598)
- Testing
- Psilocybin, Inonotus Obliquus Whole Extract
- Volunteers
- healthy volunteers welcome
- Sponsor
- Optimi Health Corporation
Substance Use, HIV Infections
Kentucky Communities and Researchers Engaging to Halt the Opioid Epidemic (CARE2HOPE)
This study will test the effects of an intervention to reduce substance use and related harms among people leaving rural jails or otherwise involved in the criminal justice system.
- Conditions
- Substance Use, HIV Infections, HCV Infection, Sexually Transmitted Infections (Not HIV or Hepatitis)
- Trial name
- NCT04134767
- Testing
- Health Linkage, Overdose Education
- Where
- United States
- Volunteers
- 234 people, healthy volunteers welcome
- Sponsor
- April M Young
Urologic Diseases, Antibacterial Drug Adverse Reaction
Audit-and-feedback to Improve Antimicrobial-prescribing Among Urologists
Antimicrobial resistance is one of today''s most urgent public health problems. An important strategy to slow the spread of antimicrobial resistance is the promotion of judicious antimicrobial use.
- Trial name
- NCT04196777
- Testing
- Audit-and-feedback
- Where
- 3 sites in United States
- Volunteers
- 525 people, healthy volunteers welcome
- Sponsor
- Iowa City Veterans Affairs Medical Center
Periodontitis, Surgery
Metronidazole vs Azithromycin in Periodontal Surgery for Patients Positive to Porphyromonas Gingivalis
The objective of this study is to determine whether, in patients with non treated periodontitis (stage III and IV) positive to Porphyromonas gingivalis, the use of systemic antimicrobials (metronidazole versus azithromycin) as an…
- Trial name
- NCT03862456
- Testing
- Azithromycin, Metronidazole
- Where
- Spain
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Contraceptive Usage
A Prospective Observational Study of the Performance of Zarin in Kenya
This will be a non-comparative prospective observational study of women using Zarin as a primary method of contraception in Kenya.
- Trial name
- NCT01334190
- Where
- Kenya
- Volunteers
- 602 people, healthy volunteers welcome
- Sponsor
- FHI 360
Driving Under the Influence, Marijuana Intoxication
Cannabis Impairment Detection Application (CIDA)
Subjects will participate in a 4-visit study protocol in which they will be asked to complete a set of computerized tasks and a 45-minute simulated drive in a driving simulator.
- Conditions
- Driving Under the Influence, Marijuana Intoxication, Alcohol Intoxication
- Trial name
- CIDA (NCT04230460)
- Testing
- Cannabis (High% THC) (Inhaled), Cannabis (Very High% THC) (Inhaled), Alcohol (oral)
- Where
- United States
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- Advanced Brain Monitoring, Inc.
Substance-Related Disorders
Resonance Breathing Intervention Opioid Use Disorder
This study aims to assess the feasibility of an intervention for the management of craving, stress, anxiety, and depression among people who use opioids via a resonance breathing smartphone app.
- Trial name
- NCT05830773
- Testing
- Resonance Breathing Exercises
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Substance Use Disorder (SUD), Drug Overdose
Justice Community Overdose Innovation Network II TCU Hub
The current study proposes to use a Hybrid Type 3 implementation research strategy to: 1) Significantly enhance our understanding of public health outcomes [e.g., overdose incidents and substance-use (SU)-related Emergency…
- Conditions
- Substance Use Disorder (SUD), Drug Overdose, Criminal Behavior
- Trial name
- JCOIN II TCU (NCT07528846)
- Testing
- Core-interagency community engagement approach, Enhanced-Core plus community engagement specialist
- Where
- United States
- Volunteers
- 1,620 people, healthy volunteers welcome
- Sponsor
- Texas Christian University
Dry Skin, Sensitive Skin
A Clinical Study to Assess the Safety, In-use Tolerability of Test Product in Healthy Adult Subjects With Dry and Sensitive Skin.
This is open-label, interventional, prospective, safety in-use tolerability study of test product "No Rays, Thanks Mineral Sunscreen" in healthy adult human subjects with dry and sensitive skin.
- Trial name
- NCT06489600
- Testing
- No Rays, Thanks Mineral sunscreen
- Where
- India
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Diet, Healthy, Health Behavior
A Food As Medicine Approach to Address Food Insecurity in Rural North Carolina
Increasing fruit and vegetable (FV) intake, and reducing saturated fat, salt, and added sugar are central lifestyle recommendations in the Dietary Guidelines for Americans to prevent chronic disease.
- Conditions
- Diet, Healthy, Health Behavior, Blood Pressure, Diabetes Mellitus Risk
- Trial name
- NCT07221045
- Testing
- PhytoRx Families: A Pilot Test to Address Food Security in Rural North Carolina
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- North Carolina State University
Gestational Diabetes, Pregnancy Related
Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes
The aim of our study is to compare neonatal and maternal outcomes using different thresholds for the initiation and titration of pharmacotherapy for gestational diabetes (GDM).
- Trial name
- START 1 (NCT06419777)
- Testing
- Insulin
- Where
- 2 sites in United States
- Volunteers
- 430 people, healthy volunteers welcome
- Sponsor
- Thomas Jefferson University
Low Back Pain, Pregnancy Related
Treatment of Low Back Pain in Pregnant Women : Uses of Drugs and Other Therapies
Low back pain is a frequent clinical condition in pregnancy. Drugs treatments are limited. Other therapies are often used, associated or not with drugs (acupuncture, manipulative medicine, physical therapies, homeopathy).
- Trial name
- LomboMat2021 (NCT05072002)
- Testing
- no intervention / observational study
- Where
- France
- Volunteers
- 370 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
HIV Prevention
Optimizing PrEP Utilization Among Alcohol and Other Drug (AOD) Using Women of Color
Nationally, the HIV case rate among black/ African American (AA) women is nearly 20 times higher than in white women; for Hispanic/Latino women it is 4.5 times higher.
- Trial name
- NCT04018651
- Testing
- PrEP Master Adherence Intervention
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Florida International University
Support Persons, Family Members
Recovery Inspired Support Engagement (RISE) Pilot
The goal of this clinical trial is to learn if a 1-on-1 support program is easy to complete and acceptable for people supporting loved ones who have recently received treatment for substance use.
- Conditions
- Support Persons, Family Members, Chosen Family, Romantic Partners
- Trial name
- (RISE) (NCT07519759)
- Testing
- ITC
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mclean Hospital
Smoking, Tobacco Use
IQOS (Non-Cigarette Tobacco Product) Pilot Study
A novel type of non-cigarette tobacco product was recently approved for sale in the US, the heated tobacco product (HTP) IQOS. IQOS may be less harmful than cigarettes, and there are some reports that it may produce more…
- Trial name
- NCT04357379
- Testing
- IQOS
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Substance Abuse, Mental Health
Optimizing a Drug Abuse Prevention Program for Dissemination
This project is a hybrid efficacy/effectiveness trial of a streamlined version of the Bridges program, an evidence-based intervention (EBI) to prevent substance abuse and mental health disorders.
- Conditions
- Substance Abuse, Mental Health, Educational Problems
- Trial name
- Bridges (NCT03125291)
- Testing
- Bridges 4-week Program
- Where
- United States
- Volunteers
- 664 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Opiate Use Disorder
Mindfulness-Oriented Recovery Enhancement (MORE) in Heroin Addiction
In this study, neuroimaging of reward processing, drug cue reactivity and inhibitory control is used before and immediately after 8 weeks of two types of group therapy in individuals with opioid addiction; clinical outcomes will…
- Trial name
- MORE (NCT04112186)
- Testing
- Behavioral group therapy #1, Behavioral group therapy #2
- Where
- United States
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Analgesia, Dexamethasone
Low-dose Intravenous Dexamethasone at Different Times as Adjunvants for Brachial Plexus Blocks
Dexamethasone has been tested as an effective adjuvant to prolong the effect of local anesthetics for peripheral nerve blocks, both perineurally and intravenously.
- Conditions
- Analgesia, Dexamethasone, Brachial Plexus Block, Intravenous Drug Usage
- Trial name
- NCT04714112
- Testing
- dexamethasone
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University Affiliated Sixth People's Hospital
Marijuana Use, Opioid Use
Reinforcing Effects of Marijuana and Opioids
The primary goals of this study are to examine 1) marijuana modulation of oxycodone self-administration and 2) oxycodone modulation of marijuana self-administration, under controlled conditions and across a range of doses for…
- Trial name
- NCT05485012
- Testing
- Marijuana, Opioid
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Shanna Babalonis, PhD