Clinical trials: Drug Use Disorder
Hepatitis C Virus (HCV)
Glecaprevir/Pibrentasvir Drug Use Results Survey in Patients Infected With Hepatitis C Virus Genotype 1-6
This multi-center, post-marketing, observational study evaluates the real world safety and effectiveness of glecaprevir plus pibrentasvir use in participants infected with the hepatitis C virus genotype 1 - 6.
- Trial name
- NCT03341871
- Where
- Japan
- Volunteers
- 1,095 people
- Sponsor
- AbbVie
Human Immunodeficiency Virus, Tuberculosis
Usability Study of IeHS in Indonesia
Technology that has a particular focus on patients' needs and ease-of-use and -access plays a significant role in the development of e-health and m-health.
- Conditions
- Human Immunodeficiency Virus, Tuberculosis, Interpersonal Relations, Mobile Phone Use
- Trial name
- NCT04179344
- Testing
- Integrated e-healthcare services (IeHS) web-based app
- Where
- 3 sites in Indonesia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bekasi City Public Hospital
Proctitis, Proctosigmoiditis
Efficacy and Safety of Budesonide Foam for Participants With Active Mild to Moderate Ulcerative Proctitis or Proctosigmoiditis
The purpose of this study is to establish the efficacy profile of rectally administered budesonide foam, as compared to an equivalent volume of rectally administered placebo foam over the same dosing schedule, in participants who…
- Trial name
- NCT01008410
- Testing
- Budesonide
- Where
- 63 sites in United States
- Volunteers
- 265 people
- Sponsor
- Bausch Health Americas, Inc.
Autism, Autistic Disorder
Use of Acupuncture In Children With Autistic Spectrum Disorder
This is a study of the efficacy of acupuncture in children with autism.
- Trial name
- NCT00352352
- Testing
- Tongue Acupuncture (Procedure)
- Where
- Hong Kong
- Volunteers
- 30 people
- Sponsor
- The University of Hong Kong
Colorectal Cancer
Phase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal Cancer
The primary objective of the Phase II portion of this study is to assess the efficacy of KRN330 in combination with irinotecan after first-line or adjuvant FOLFOX (5-fluorouracil, leucovorin, and oxaliplatin)/CapOx (capecitabine…
- Trial name
- NCT00838578
- Testing
- KRN330, Irinotecan
- Where
- 12 sites in United States
- Volunteers
- 65 people
- Sponsor
- Kyowa Kirin Co., Ltd.
Dentin Hypersensitivity
Evaluation of the Combined Effect of Bioactive Toothpastes, Desensitizing Agents and Er-YAG Laser on Dentin Hypersensitivity: an In-Vivo Study
Here's the revised version with the corrected treatment and follow-up session schedule: --- The aim of this clinical trial is to evaluate the effectiveness of bioactive toothpastes, desensitizing agents, and Er-YAG laser…
- Trial name
- NCT06854068
- Testing
- laser treatment, application of desensitizing agent
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ege University
Psoriasis
Efficacy Study of the Combination Mometasone + Salicylic Acid in Patients With Psoriasis
To evaluate the efficacy of the combination of mometasone furoate 0.1% and Salicylic Acid 5% in patients of both sexes who presented clinical symptoms of psoriasis of mild to moderate.
- Trial name
- Psoriasis (NCT01229085)
- Testing
- memotasone + salicylic acid
- Where
- Brazil
- Volunteers
- 71 people
- Sponsor
- Azidus Brasil
Multiple Myeloma
Study of Vorinostat (MK-0683) or Placebo, in Combination With Bortezomib in Participants With Multiple Myeloma (MK-0683-088 AMN)
Study of the efficacy and safety of bortezomib administered in combination with vorinostat in patients with relapsed or refractory multiple myeloma.
- Trial name
- NCT00773747
- Testing
- Vorinostat, bortezomib
- Volunteers
- 637 people
- Sponsor
- Merck Sharp & Dohme LLC
Asthma
A Study to Evaluate the Relationship Between Use of Albuterol Multidose Dry Powder Inhaler With an eModule (eMDPI) and Exacerbations in Participants With Asthma
This is a Phase 3B, 12-week, multicenter, open-label study to evaluate the relationship between albuterol sulfate (ABS) eMDPI and clinical asthma exacerbation (CAE) in adult participants at least 18 years of age with…
- Trial name
- NCT02969408
- Testing
- Albuterol Sulfate
- Where
- 44 sites in United States
- Volunteers
- 397 people
- Sponsor
- Teva Branded Pharmaceutical Products R&D, Inc.
Alcohol Use Disorder, Drug Use
A Hybrid Effectiveness Implementation Study of Latino/a Alcohol and Drug Users
Alcohol use is a significant problem among Latinxs and immigration-related stress increases risk for substance use. A theoretically-based cultural adaptation of motivational interviewing (CAMI) that specifically integrated…
- Conditions
- Alcohol Use Disorder, Drug Use, Psychological Distress
- Trial name
- CAMI-HI (NCT04771650)
- Testing
- CAMI
- Where
- 2 sites in United States
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Boston University Charles River Campus
Nicotine Withdrawal, Nicotine Addiction
Acute Pharmacokinetic and Pharmacodynamic Effects of "Tobacco-Free" Oral Nicotine Pouches in Smokers
The purpose of the present study is to examine the pharmacokinetics and pharmacodynamics of "tobacco-free" oral nicotine pouches, at various doses and flavors, in healthy adult smokers.
- Conditions
- Nicotine Withdrawal, Nicotine Addiction, Drug Effect
- Trial name
- NCT05335915
- Testing
- Nicotine, Cigarette
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal
Musical Mindfulness for Pain in the ED Waiting Room
Studies have shown that 60-70% of patients in the Emergency Department (ED) experience pain. With pain being such a broad issue in the ED, the ED is expected to deliver safe and effective treatment of pain.
- Conditions
- Music Therapy for Pain and Sedation, Neck Pain Musculoskeletal, Back Pain
- Trial name
- NCT07391891
- Testing
- Music intervention
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of California, Irvine
Osteoarthritis
Study to Compare Prescription Non-Steroidal Anti-Inflammatory Drug (NSAID) Changes, Health Care Utilization, Efficacy and Safety of Meloxicam 7.5 mg Versus Usual Care Administration of Prescription NSAIDs in a Managed Healthcare Setting in Patients With Osteoarthritis
Study to compare the percentage of treatment successes or failures in patients randomized to meloxicam 7.5 mg vs. usual care prescription NSAIDs.
- Trial name
- NCT02183064
- Testing
- Meloxicam, NSAID
- Volunteers
- 1,309 people
- Sponsor
- Boehringer Ingelheim
Opioid Use Disorder (OUD), Addictology
Autonomous Methadone Delivery System by Nurses
Initiations of methadone treatment for opiode use disorder (OUD) are carried out in France in specialized centers, known as centers for care, support and prevention in addictology (CSAPA) In this way, hospital practitioners…
- Trial name
- DIADEME (NCT07085377)
- Testing
- DIADEME strategy, Controle strategy, Individual semi directive interview
- Where
- 8 sites in France
- Volunteers
- 182 people
- Sponsor
- Hospices Civils de Lyon
Opioid Use Disorder
Adapting the HOPE Online Support Intervention to Increase Uptake of Medications for Opioid Use Disorder
In a randomized controlled trial, with 3, 6-month and 1-year follow-up, this application aims to explore whether and how the HOPE intervention can be adapted to increase MOUD uptake among OUD patients, assess the effectiveness of…
- Trial name
- HOPE MOUD (NCT04712981)
- Testing
- HOPE
- Where
- United States
- Volunteers
- 640 people
- Sponsor
- University of California, Irvine
Acne Vulgaris
Drug Utilization Study on Diane-35 (and Generics) in Three European Healthcare Databases
The study objectives are to characterize new users of Cyproterone Acetate / Ethinylestradiol (CPA/EE) in 2011/2012 and in 2014 according to demographics, treatment characteristics, previous diagnosis of acne, hirsutism or other…
- Trial name
- NCT02349399
- Testing
- Cyproterone / Ethinylestradiol (Diane-35, BAY86-5264) and its Generics
- Where
- 3 sites in Italy, Netherlands and 1 more
- Volunteers
- 26,065 people, healthy volunteers welcome
- Sponsor
- Bayer
Heart Failure
Forxiga HF General Drug Use-Results Study
To capture safety when Forxiga is administered to patients with HF in clinical practice after launch.
- Trial name
- NCT04865406
- Where
- 45 sites in Japan
- Volunteers
- 1,221 people
- Sponsor
- AstraZeneca
Myocarditis, Cardiomyopathies
JOint Use of Database to Identify Risk Factors of CARDio-vascular Toxicity Induced by Immune Checkpoint Inhibitors
Immune checkpoint inhibitors (ICIs) might induce high grade immune-related adverse events (irAEs) involving the cardio-vascular system.
- Conditions
- Myocarditis, Cardiomyopathies, Heart Diseases, Cardiovascular Diseases
- Trial name
- JOCARDITE (NCT04294771)
- Testing
- ICI
- Where
- France
- Volunteers
- 500,000 people
- Sponsor
- Groupe Hospitalier Pitie-Salpetriere
Adverse Reaction to Drug, Health Behavior
Personal Health Records and Elder Medication Use Quality
Purpose: To examine the impact of a personal health record (PHR) on medication use safety among older adults. Background: Online PHRs have potential as tools to manage health information.
- Conditions
- Adverse Reaction to Drug, Health Behavior, Medication Adherence, Physician-Patient Relations
- Trial name
- NCT02012712
- Testing
- Personal Health Record (PHR)
- Where
- United States
- Volunteers
- 1,163 people
- Sponsor
- University of Iowa
Asthma, Healthy
Effects of Salbutamol in Athletes and Implications for Screening and Sports
β2-Agonists, commonly used to treat asthma, have also been used by athletes to enhance performance, leading to their ban by the International Olympic Committee in 1972.
- Conditions
- Asthma, Healthy, Effect of Drug
- Trial name
- NCT07037511
- Testing
- Salbutamol
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
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