Clinical trials: Dry Eye, completed
Dry Eye Syndromes
A Prospective, Randomized, Placebo and Active Comparator Controlled Study of CP-690,550 in Subjects With Dry Eye.
A prospective, randomized, placebo and active comparator controlled study of CP-690,550 in subjects with dry eye.
- Trial name
- NCT00784719
- Testing
- CP-690,550, Cyclosporine, CP-690,550 Vehicle
- Where
- 27 sites in United States
- Volunteers
- 327 people
- Sponsor
- Pfizer
Meibomian Gland Dysfunction, Dry Eye
Comparison of BlephEx to MiBoflo as Treatment Options for Blepharitis
The goal of this study is to compare which treatment - BlephEx or MiBoFlo - will be a better option for patients suffering from dry eye secondary to Meibomian Gland dysfunction.
- Conditions
- Meibomian Gland Dysfunction, Dry Eye, Posterior Blepharitis
- Trial name
- NCT02952079
- Testing
- Blephex, MiboFlo
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of the Incarnate Word
Eye Diseases, Ocular Surface Disease
Effect on Ocular Surface Symptoms of Online Education
retrospective, observational study.
- Conditions
- Eye Diseases, Ocular Surface Disease, Dry Eye
- Trial name
- NCT04960696
- Testing
- OSDI, tear break up time, schirmer
- Where
- Turkey (Türkiye)
- Volunteers
- 315 people
- Sponsor
- Kahramanmaras Sutcu Imam University
Dry Eye Disease, Meibomian Gland Dysfunction
Feasibility of IPL Combined With RF for Treatment of DED Due to MGD
The purpose of this single-arm pilot study is to evaluate the feasibility and safety of combination therapy of intense pulsed light (IPL) and (Radiofrequency) RF for treatment of Dry eye disease (DED) due to Meibomian gland…
- Trial name
- NCT05487547
- Testing
- IPL_RF_MGX
- Where
- 2 sites in United States
- Volunteers
- 33 people
- Sponsor
- Lumenis Be Ltd.
Keratoconjunctivitis Sicca, Dry Eye Syndromes
Differential Diagnosis of Sjögren's Versus Non-Sjögren's Dry Eye
To investigate and compare the burden of dry eye in Sjögren's syndrome dry eye vs non-Sjögren's syndrome dry eye, as well as investigate the diagnostic potential of tear film mucins and various inflammatory cytokines evaluated by…
- Conditions
- Keratoconjunctivitis Sicca, Dry Eye Syndromes, Ocular Surface Disease, Sjogren's Syndrome
- Trial name
- NCT04493658
- Testing
- Questionnaires, Tear fluid sampling, Impression Cytology
- Where
- United States
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Dry Eye, Vision; Disturbance, Hysterical
The Influences of Dry Eye Disease on Optical Quality
DED could result in visual disturbance and damage optical quality. We aimed to evaluate the influences of dry eye disease (DED) on optical quality and their correlations.
- Trial name
- NCT04043949
- Where
- China
- Volunteers
- 90 people
- Sponsor
- Peking University Third Hospital
Dry Eye Syndromes
Multicenter Trial Evaluating Quality of Tears Produced by Nasal Neurostimulation
The objectives of this study are: To compare the change in levels of tear proteins and inflammatory mediators pre and post administration between the intranasal and extranasal applications To compare the goblet cell count…
- Trial name
- NCT02385292
- Testing
- Oculeve Intranasal Lacrimal Neurostimulator
- Where
- 2 sites in United States
- Volunteers
- 23 people
- Sponsor
- Oculeve, Inc.
Geographic Atrophy, Dry Age Related Macular Degeneration
Study of Fenretinide in the Treatment of Geographic Atrophy Associated With Dry Age-Related Macular Degeneration
The purpose of this phase II study is to determine the efficacy of fenretinide in the treatment of geographic atrophy (GA) in subjects with the dry form of age-related macular degeneration (AMD).
- Trial name
- NCT00429936
- Testing
- Fenretinide
- Volunteers
- 245 people
- Sponsor
- Sirion Therapeutics, Inc.
Dry Eye
Acupoint Therapy Device for Dry Eye
To built a dry eye acupoint therapeutic instrument by stimulating acupoints with low impulse current .And the safety of the dry eye acupoint treatment device will be tested and the initial validation will be verified.
- Trial name
- NCT06720428
- Testing
- dry eye acupoint therapy instrument, Artificial tear
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Shanghai 10th People's Hospital
Graft vs Host Disease, Sjogren's Disease
Cord Blood Serum in the Treatment of Ocular Surface Diseases
Human autologous serum (AS) eye drops have been successfully used in the treatment of severe ocular surface disorders and the enhancement of corneal wound healing, due to their growth factor (GF) content.
- Trial name
- NCT01234623
- Testing
- UCS eyedrops
- Where
- Italy
- Volunteers
- 30 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Dry Eye, Tear Film
Effects of Two Tear Substitutes in Patients With Dry Eye Syndrome
With the potential to address evaporative dry eye, Liposic and Tears Naturale Forte have been developed in which phospholipid liposomes are delivered to the tear film via the surface of the closed eyelid.
- Conditions
- Dry Eye, Tear Film, Lipid Layer, Liposic
- Trial name
- NCT03211351
- Testing
- Liposic, Tears Naturale Forte
- Where
- China
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Huaxia Eye Hospital Group
Dry Eye Disease (DED)
Vizol S DIGI EYE Efficacy and Safety Study in Patients With Dry Eye
The clinical investigation was intended to investigate the efficacy, ocular tolerability and safety of Vizol S DIGI EYE, a new eye drops, solution developed by JADRAN - GALENSKI LABORATORIJ d.d., in patients with moderate to…
- Trial name
- NCT07050446
- Testing
- Vizol S DIGI EYE eye drops, 0,9% saline solution, eye drops
- Where
- 3 sites in Serbia
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Jadran Galenski laboratorij d.d.
Geographic Atrophy
Safety and Efficacy Assessment Treatment Trials of Emixustat Hydrochloride
The purpose of this study is to determine if emixustat hydrochloride (ACU-4429) reduces the rate of progression of geographic atrophy compared to placebo in subjects with dry age-related macular degeneration.
- Trial name
- SEATTLE (NCT01802866)
- Testing
- ACU-4429
- Where
- United States
- Volunteers
- 508 people
- Sponsor
- Kubota Vision Inc.
Dry Eye Syndrome, Keratoconjunctivitis Sicca
A Study to Evaluate the Safety and Effectiveness of Oculeve Intranasal Lacrimal Neurostimulator in Participants With Dry Eye Syndrome
The purpose of this study is to compare acute tear production produced by the Oculeve Intranasal Lacrimal Neurostimulator with two control devices in participants with aqueous tear deficiency.
- Trial name
- NCT02680158
- Testing
- Oculeve Intranasal, Oculeve Extranasal
- Where
- 2 sites in United States
- Volunteers
- 48 people
- Sponsor
- Oculeve, Inc.
Dry Eye
Assess the Safety and Efficacy of CsA Ophthalmic Gel in Subjects With Dry Eye
The purpose of this study is to explore the efficacy and safety of CsA ophthalmic gel in the treatment of moderate to severe tear deficiency dry eye with different dosage, frequency and concentration, and to preliminarily…
- Trial name
- NCT03676335
- Testing
- CsA eye gel, CsA for eye emulsion, Hypromellose Eye Drops
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd.
Dry Eye
Efficacy and Safety Study of FID 119515A
The purpose of this study was to compare the effect of FID 119515A to Blink® Tears on the integrity of tear film in adults with a history of dry eye in both eyes.
- Trial name
- NCT01833117
- Testing
- FID 119515A, Blink® Tears
- Volunteers
- 75 people
- Sponsor
- Alcon Research
Dry Eye, Sjogren Syndrome
Comparing Efficacy of Autologous Serum Eye Drops With and Without Insulin in Autoimmune Dry Eye.
Introduction: Dry Eye Disease (DED) of autoimmune origin is often severe and resistant to conventional treatments, necessitating alternative therapeutic options.
- Trial name
- NCT06931041
- Testing
- recombinant human insulin, Autologous serum
- Where
- Mexico
- Volunteers
- 25 people
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana
Dry Eye Syndromes
The Effect of Oral Zanthoxylum Schinifolium Seed Oil in Individuals With Dry Eye Disease
The purpose of this study is to evaluate the clinical efficacy and safety of 10-weeks oral consumption of Zanthoxylum schinifolium seed Oil (ZSO) in patients with mild dry eye disease.
- Trial name
- NCT02802150
- Testing
- Zanthoxylum Schinifolium Seed Oil(4g/day)
- Where
- 2 sites in South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Chonbuk National University Hospital
Rheumatoid Arthritis, Lupus Erythematosus, Systemic
Lessening the Impact of Fatigue in Inflammatory Rheumatic Diseases
Fatigue is common and disabling for most patients with inflammatory rheumatic disease. Therapies designed to improve physical activity and 'talking' treatments, which positively help patients change the way they think and behave…
- Conditions
- Rheumatoid Arthritis, Lupus Erythematosus, Systemic, Axial Spondyloarthritis, Psoriatic Arthritis
- Trial name
- LIFT (NCT03248518)
- Testing
- Usual Care, Cognitive behavioural approach, Personalised Exercise Programme
- Where
- 6 sites in United Kingdom
- Volunteers
- 368 people
- Sponsor
- University of Aberdeen
Nonexudative Age-Related Macular Degeneration, Unspecified Eye, Intermediate Dry Stage
A Study of an Encapsulated Cell Technology (ECT) Implant for Patients With Atrophic Macular Degeneration
The purpose of this study is to look at the safety and effectiveness of CNTF implants on vision in participants with atrophic macular degeneration.
- Trial name
- NCT00447954
- Testing
- High Dose NT-501 implant, Low Dose NT-501 implant
- Where
- 8 sites in United States
- Volunteers
- 53 people
- Sponsor
- Neurotech Pharmaceuticals
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.