Clinical trials: Duloxetine
Healthy
Tolerability and Safety of Duloxetine BID in Healthy Female Subjects
Study to assess the safety and tolerability of 100 mg of duloxetine BID compared to 40 mg of duloxetine BID or placebo for 7 days
- Trial name
- NCT02232542
- Testing
- Duloxetine - low dose, Duloxetine - high dose
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Fibromyalgia
Cymbalta for Fibromyalgia Pain - Predictive Value of Small Fiber Changed
Subjects with Fibromyalgia who respond to Duloxetine have specific nerve fiber characteristics. This can be used to predict which future patients will respond to Duloxetine.
- Trial name
- NCT01619566
- Testing
- Duloxetine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, San Diego
Osteoarthritis
Duloxetine in Osteoarthritis (OA) Pain
This study aims to determine in people with knee Osteoarthritis (OA) if relief of pain after treatment with either duloxetine or placebo is associated with changes in brain anatomy.
- Trial name
- NCT01558700
- Testing
- Duloxetine, Sugar pill
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Northwestern University
Intervertebral Disc Degeneration
Duloxetine as an Analgesic Agent in Patients Undergoing Elective Spine Surgery
Duloxetine as an analgesic agent in patients undergoing elective spine surgery: evaluation with fentanyl demand controlled by the patient.
- Trial name
- Duloxetine (NCT02535000)
- Testing
- Duloxetine
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Serviço de Anestesiologia de Joinville
Major Depressive Disorder
Duloxetine for Major Depression in Peri-/Postmenopausal Women
The main objective of this study is to characterize a range of brain activation symptoms associated with major depression in peri- and post-menopausal women.
- Trial name
- NCT00889369
- Testing
- Duloxetine
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Hamilton Health Sciences Corporation
Pain
Improvement the Anti-migraine Treatment Efficacy by Tailoring the Drug to Individual's Pain Modulation Profile
To delineate brain mechanisms that subserve endogenous analgesic (EA) in the healthy state. To identify alterations in mechanisms supporting EA in chronic pain (migraine) and their therapeutic relevance.
- Trial name
- NCT01470339
- Testing
- duloxetine
- Where
- Israel
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Depressive Disorder
The Effect of Duloxetine on Interoceptive Awareness
This study focuses on possible mechanism mediating duloxetine effects on painful physical symptoms in patients suffering from MDD.
- Trial name
- NCT00337012
- Where
- Germany
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University Hospital, Bonn
Drug-drug Interaction
A Phase 1, Drug Interaction Study Between AVP-786 and Paroxetine and Between AVP-786 and Duloxetine in Healthy Subjects
To assess steady state pharmacokinetics (PK), safety and tolerability between AVP-786 (deuterated [d6] dextromethorphan hydrobromide [DM]/quinidine sulfate [Q]) and paroxetine and between AVP-786 and duloxetine.
- Trial name
- NCT02174822
- Testing
- AVP-786, Paroxetine, Duloxetine
- Where
- Australia
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Otsuka Pharmaceutical Development & Commercialization, Inc.
Healthy
Bioavailability Study of Duloxetine Delayed-Release Capsules 60 mg Under Fasting Condition
This study were to compare the relative bioavailability of Duloxetine HCl delayed release capsule 60 mg with that of 'CYMBALTA®' delayed release capsule 60 mg (Duloxetine HCl delayed release capsule 60 mg) in healthy, adult…
- Trial name
- NCT02291367
- Testing
- Duloxetine, Cymbalta®
- Where
- India
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Healthy
Bioavailability Study of Duloxetine Delayed-Relase Capsules 60 mg Under Fed Condition
This study were to compare the relative bioavailability of Duloxetine HCl delayed release capsule 60 mg with that of 'CYMBALTA®' delayed release capsule 60 mg (Duloxetine HCl delayed release capsule 60 mg) in healthy, adult…
- Trial name
- NCT02291341
- Testing
- Duloxetine, Cymbalta®
- Where
- India
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Dr. Reddy's Laboratories Limited
Major Depressive Disorder
Dose Escalation, Double-Blind Treatment With Duloxetine Hydrochloride Once Daily Dosing for Evaluation of Safety in Major Depression
The Purposes of this Study are to determine: The safety of duloxetine and any side effects that might be associated with it. Whether duloxetine can help patients with major depression.
- Trial name
- NCT00042575
- Testing
- Duloxetine
- Where
- 9 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Eli Lilly and Company
Osteo Arthritis Knee
Efficacy of Duloxetine Compared to NSIADs in Osteoarthritis of Knee
Osteoarthritis (OA) is the most common degenerative joint disease, affecting more than 25% of the population . Knee OA is an insidious disease related to structural changes in the joint over many years.
- Trial name
- Duloxetine (NCT05486026)
- Testing
- Duloxetine 30 MG, Nonsteroidal Antiinflammatory Drug
- Where
- Iraq
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hawler Medical University
Pain
Pain Prevention and Treatment Through the Enhancement of the Anti-nociceptive Component of Pain Modulation Profiles
To utilize the plasticity of the central pain pathways in order to (i) shift individuals with a pro-nociceptive pain modulation profile towards an anti-nociceptive one, and (ii) assess its relevance in minimizing pain-derived…
- Trial name
- NCT02020122
- Testing
- Duloxetine, Pregabalin
- Where
- Israel
- Volunteers
- 5 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus