Clinical trials: Dupuytren Disease
Dupuytren's Disease
Palmaris Longus Muscle and Dupuytren
Dupuytren disease is a medical condition characterized by the painless formation of nodules in the palm of the hand. Cords are formed on the palmar fascia, a connective tissue sheet in the palm of the hand.
- Trial name
- Palmaris (NCT06281509)
- Testing
- Non-invasive tests to determine the presence or absence of the palmaris longus tendon in both hands., Ultrasound
- Where
- Belgium
- Volunteers
- 243 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Dupuytren Contracture, Dupuytren's Disease
Effectiveness of Splinting After Collagenase Injection
Dupuytren disease is a fibroproliferative condition of the palmar and digital fascia. A collagen containing cord forms which can lead to fixed flexion contracture of one or more fingers.
- Trial name
- NCT04874870
- Testing
- Collagenase Clostridium Histolyticum 0.9 MG [Xiaflex], Xiaflex + Hand-Based Custom Orthosis
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Foundation for Orthopaedic Research and Education
Dupuytren Contracture, Dupuytren's Disease
Effectiveness of Night Splinting After Percutaneous Needle Fasciotomy in Dupuytren's Contracture
Dupuytren's contracture (DC) is associated with progressive finger flexion and extension deficit caused by fibrosis in the palm and digits.
- Trial name
- NCT05300893
- Testing
- No night splint
- Where
- 3 sites in Sweden
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Uppsala University
Dupuytren's Disease
Evaluation of Xiaflex: Trial of Effectivenss iN Dupuytren's
This is a prospective, multi-centre, pragmatic randomized controlled trial to compare both the clinical effectiveness and cost-effectiveness of collagenase injections (CI) versus limited palmar fasciectomy (LPF) to determine if…
- Trial name
- EXTEND (NCT02725528)
- Testing
- collagenase injection, limited palmar fasciectomy
- Where
- 10 sites in Canada
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- McMaster University
Dupuytren's Disease
Safety and Efficacy of Delayed Manipulation After Xiaflex Treatment in Subjects With Dupuytren's Contracture
The purpose of this study is to determine if of manipulation of digits following collagenase injection for treatment of Dupuytren's contracture is effected by the amount of time between injection and manipulation.
- Trial name
- NCT01226121
- Testing
- Clostridial collagenase injectable
- Where
- 2 sites in United States
- Volunteers
- 37 people, healthy volunteers welcome
- Sponsor
- Indiana Hand to Shoulder Center