Clinical trials: Durability
Influenza
Immune Response Following Seasonal Influenza Vaccination
This is an open-label, single administration dose study in adult healthy male and female subjects. After qualifying for the study, subjects will receive a single intramuscular injection of the FDA approved 2016-2017 quadrivalent…
- Trial name
- NCT03163342
- Testing
- Licensed seasonal influenza vaccine
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Altimmune, Inc.
Prosthesis Durability
Hyoid Displacement During Swallowing Function for Completely Edentulous Subjects
To investigate the effect of wearing mandibular implant retained overdentures on superior and anterior hyoid displacement during swallowing process.
- Trial name
- NCT06187181
- Testing
- implant overdenture, videofluroscopy
- Where
- Egypt
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Mansoura University
HIV Infections
Durability of Adherence in Self-Management of HIV
Adherence to highly active antiretroviral therapy (HAART) is critical to successful treatment of HIV. This study tested an intervention that helps people infected with HIV take all their medications when and how they were…
- Trial name
- DASH (NCT00991302)
- Testing
- CAP-IT
- Where
- 2 sites in United States, Peru
- Volunteers
- 172 people, healthy volunteers welcome
- Sponsor
- Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections
Prosthesis Durability
Ultrasound Investigation of Tongue Movement for Implant Overdenture
This study aimed to examine the impact of mandibular implant overdentures on tongue movement during mastication.
- Trial name
- NCT06705114
- Testing
- complete denture, implant overdenture
- Where
- Egypt
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Skin Hydration in Healthy Volunteers
Durability of Two Skin Barrier Protectants (SBP)
The current study will evaluate the duration of wear and durability of two commercially available SBPs: Medline Marathon® XL (extra long) No Sting Cyanoacrylate Skin Protectant (henceforth referred to as "Marathon®") and 3M™…
- Trial name
- NCT05756348
- Testing
- Marathon® XL No Sting Cyanoacrylate Skin Protectant and 3M™ Cavilon™ Advanced Skin Protectant
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Medline Industries
Prosthesis Durability
All on Four Versus All on Three Implant Treatment Concepts
the evaluation of patient satisfaction of All on-4 versus All on-3 implant treatment concepts rehabilitation of atrophied mandibular ridge.
- Trial name
- NCT05912127
- Testing
- implant supported fixed full arch prosthesis
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Vaccinia, Virus Diseases
Evaluating the Human Immune Response to the JYNNEOS Vaccine
This study is designed to evaluate the magnitude and duration of the human adaptive immune response to the JYNNEOS Modified Vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccine in the blood, lung mucosa, skin and bone marrow.
- Trial name
- NCT06366672
- Testing
- JYNNEOS (Smallpox and Monkeypox Vaccine, Live, Nonreplicating) suspension for subcutaneous injection, Phlebotomy, Research bronchoscopy
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Washington University School of Medicine
Malaria
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Burkina Faso
The use of insecticide-treated bed nets (ITN) has contributed to the substantial reduction in malaria cases and deaths. This progress is threatened by increasing resistance commonly used insecticides in mosquito populations.
- Trial name
- NCT04157894
- Testing
- Standard long-lasting insecticidal net, Chlorfenapyr insecticide treated net, Piperonyl butoxide long-lasting insecticidal net
- Where
- Burkina Faso
- Volunteers
- 5,606 people, healthy volunteers welcome
- Sponsor
- PATH
Covid19
Characterization and Durability of COVID-19 Vaccine Induced Immune Responses in Healthcare/Frontline Workers
Rationale: Early in the covid-19 pandemic, it was unclear whether and how individuals and populations would develop protective and enduring immunity against SARS-CoV-2, either after infection or vaccination.
- Trial name
- NCT05049187
- Where
- India
- Volunteers
- 132 people, healthy volunteers welcome
- Sponsor
- Tuberculosis Research Centre, India
Prosthesis Durability
Effect of Geometric Modifications of Implant Scan Bodies
The aim of this clinical study will be the effect of geometric modifications of implant scan bodies compared to conventional transfer techniques on passivity of all on four mandibular restorations
- Trial name
- NCT06040385
- Testing
- Implant supported hybrid prosthesis
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Malaria
Estimating the Malaria Prevention Impact of New Nets: Observational Analyses to Evaluate the Evidence Generated During Piloted New Net Distributions in Rwanda
The use of insecticide-treated bed nets (ITNs) has contributed to the substantial reduction in malaria cases and deaths. This progress is threatened by increasing resistance in mosquito populations to commonly used insecticides.
- Trial name
- NCT04230161
- Testing
- Standard long-lasting insecticidal net, Chlorfenapyr insecticide treated net, Indoor residual spraying
- Where
- Rwanda
- Volunteers
- 3,502 people, healthy volunteers welcome
- Sponsor
- PATH
Edentulous Mouth, Quality of Life
Impact of Retro-molar Pad Demarcation on Complete Denture Wearers' Satisfaction
the retromolar pad is a critical anatomical landmark in the lower edentulous arch marking the posterior end of any removable prosthesis.
- Conditions
- Edentulous Mouth, Quality of Life, Patient Satisfaction, Complete Edentulism
- Trial name
- RMP (NCT07246343)
- Testing
- carving of retromolar pad area (RMP), no carving of the retromolar pad area (RMP)
- Where
- Jordan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Samiha Sartawi
Prostheses Durability
Triple-Scan Protocol to Assess Passivity
Quantification and visualization the internal and marginal gaps by newer digital methods, such as the triple-scan protocol described by Borga Dönmez et al.
- Trial name
- NCT07644689
- Testing
- Conventional Impression Technique, Digital Impression with Nonmodified Scan Body, Digital Impression with Modified Scan Body
- Where
- Egypt
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Stress Urinary Incontinence
Mesh-free Suture Urethropexy for Treating Stress Urinary Incontinence, Efficacy and Durability Trial
In this proposed study, the investigators aim to evaluate a modified suture urethropexy technique for the treatment of female stress urinary incontinence.
- Trial name
- NCT04881721
- Testing
- Urethropexy
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Endeavor Health
Missing Teeth, Partial-edentulism
Retention and Durability of the Anterior Zirconia Wing Bridge
This study is a clinical trial to determine the retention and durability of the anterior zirconia wing bridge. The type of zirconia-wing bridge the investigators are researching in this study has two wings which generally have…
- Trial name
- NCT04378140
- Testing
- zirconia wing bridge
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Roseman University of Health Sciences
Influenza A Subtype H5N1 Infection
Durability and Impact of the Seasonal Influenza Vaccine on H5 Induced B Cell Response
The study is a prospective single site exploratory study to examine the impact of Food and Drug Administration (FDA) approved seasonal flu vaccine on the immune responses of H5N1 vaccine previously received with or without the…
- Trial name
- HIPCVAX-010S (NCT03701061)
- Testing
- Seasonal Influenza Vaccine
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Emory University
Prosthesis Durability
Edentulous Maxilla Opposed by 2-implant Mandibular Overdenture?
This within -subject study will be conducted to evaluate the proper number of unsplinted implants ;( three, four and five implants) for the edentulous maxilla opposed by mandibular two-implant overdentures.
- Trial name
- NCT06050213
- Testing
- Maxillary implant overdenture
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Wear Comfort, Retention
3D Printed vs. Milled Occlusal Splints in Dentistry
This crossover study aims to evaluate the wear comfort, retention, and stability of 3D-printed and milled occlusal splints in healthy subjects.
- Conditions
- Wear Comfort, Retention, Stability
- Trial name
- Splints (NCT07236294)
- Where
- Netherlands
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Ridge Preservation Technique
The Effect of Tetracycline in Degradation and Permeability of Collagen Membrane
The main objective of this study was to evaluate the histological impact of treatment with tetracycline (TTC) solution of two layers collagen membranes (CMs) bio-degradation, in ridge preservation technique (RPT).
- Trial name
- NCT02057926
- Testing
- The effect of tetracycline in degradation and permeability of collagen membranes.
- Where
- Spain
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
SARS-CoV Infection
COVID-19 Vaccine Response in Chronic Respiratory Conditions
The investigators will assess the antibody, T cell and B cell responses to SARS-CoV-2 vaccination before and every 3 months for 18 months after the initial vaccination or subsequent vaccinations (boosters) in adults and children…
- Trial name
- NCT05313087
- Testing
- COVID-19 vaccine
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- National Jewish Health