Clinical trials: Dysfunction of Eustachian Tube
Eustachian Tube Disorder
Evaluating Changes in Middle Ear Pressure Caused by CPAP
This study is an investigation into the effect that CPAP has on the pressure in the middle ear. It will evaluate the middle ear pressure and ear drum appearance at multiple levels of CPAP pressure delivered via a full face mask.
- Trial name
- NCT02882022
- Testing
- Continuous positive airway pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Virginia
Eustachian Tube Dysfunction
Efficacy of Buteyko Breathing in Seniors With Chronic Eustachian Tube Dysfunction
Eustachian tube dysfunction is distressing probelm. drugs usually are not effective. compelemtary tehrapies like Buteyko breathing may be effective
- Trial name
- NCT07193485
- Testing
- Buteyko breathing, usual care
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Eustachian Tube Dysfunction
XprESS ET Registry
A prospective, multicenter, registry of patients undergoing balloon dilation of the Eustachian tubes (ET).
- Trial name
- NCT04136977
- Testing
- Eustachian tube dilation
- Where
- 11 sites in United States
- Volunteers
- 169 people
- Sponsor
- Entellus Medical, Inc.
Tobacco Smoking, Eustachian Tube Dysfunction
Buteyko Breathing and Approach of Smoking Hygiene: Effects on Dysfucntion of Eustachian Tube and Lung Functions
adolescents are usually exposed to tobacco smoke passively. this can reduce their lung functions and negatively impact functions of Eustachian tube.
- Trial name
- NCT07236580
- Testing
- Buteyko breathing plus smoking hyeigne approach, smoking hygiene appraoch
- Where
- Egypt
- Volunteers
- 40 people
- Sponsor
- Cairo University
Otitis Media, Serous, Negative Middle Ear Pressure
Short Term Relief of Eustachian Tube Dysfunction and Serous Otitis Media Using Intranasal Steroid Sprays
We hypothesize that intranasal steroid application will have a beneficial therapeutic effect in adults with regard to resolution of serous otitis media and/or negative middle ear pressure, as compared to placebo.
- Conditions
- Otitis Media, Serous, Negative Middle Ear Pressure, Rhinitis, Otitis Media With Effusion
- Trial name
- NCT00279916
- Testing
- Triamcinolone acetonide nasal spray
- Where
- United States
- Volunteers
- 91 people
- Sponsor
- Mayo Clinic
Eustachian Tube Dysfunction, Barotitis
Efficacy of Balloon Dilation of the Eustachian Tube in Eustachian Tube Dilatory Dysfunction
This study is being conducted to learn more about a procedure, balloon dilation of the eustachian tube, in treating patients with eustachian tube dysfunction.
- Trial name
- NCT05719207
- Testing
- Balloon dilation of eustachian tube
- Where
- 2 sites in Canada
- Volunteers
- 76 people
- Sponsor
- University of Calgary
Eustachian Tube Dysfunction, Laryngopharyngeal Reflux
The Study of Eustachian Tube Dysfunction and Laryngopharyngeal Reflux
The purpose of this study is to investigate the relationship between ear fullness, pressure, and/or pain and laryngopharyngeal reflux, in order to focus medical therapy and improve therapeutic outcomes in this patient population.
- Trial name
- ETDLPR (NCT02123498)
- Testing
- Omeprazole, Ranitidine, Pantoprazole
- Where
- 2 sites in United States
- Sponsor
- Loma Linda University
Balloon Eustachian Tuboplasty
The Therapeutic Effect of BET in COM With ETD
Currently, surgical treatment of patients with chronic otitis media is one of the most important treatment methods. However, the current results show that some patients with eustachian tube dysfunction can't reconstruct the…
- Trial name
- NCT03440710
- Testing
- BET
- Where
- China
- Volunteers
- 60 people
- Sponsor
- Eye & ENT Hospital of Fudan University
Eustachian Tube Dysfunction, Chronic Otitis Media
Risk Factors and Potential Causes of Eustachian Tube Dysfunction in Adults
This research study measures how well the Eustachian tube works and looks directly at the anatomy of the Eustachian tube in adults who have had tympanostomy tubes surgically inserted into their eardrums because they have been…
- Trial name
- NCT01251432
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Pittsburgh
Pain, Anxiety
Active vs. Passive VR During Office-based ENT Procedures
The purpose of this research is to evaluate whether active virtual reality reduces pain and anxiety more effectively than passive virtual reality during office-based ENT procedures.
- Conditions
- Pain, Anxiety, Chronic Rhinosinusitis (CRS), Nasal Obstruction
- Trial name
- NCT07599826
- Testing
- Passive virtual reality headset or goggles, Active virtual reality headset or goggles
- Where
- United States
- Volunteers
- 132 people
- Sponsor
- Cedars-Sinai Medical Center
Patulous Eustachian Tube Dysfunction
A Trial of Clay Weight on the Ear Drum for Patulous Eustachian Tube
The Eustachian tube is a tube that connects the back of the nose with the ear. Its job is to keep the pressure on the inside of the eardrum close to the pressure outside the eardrum, so that the eardrum can vibrate properly.
- Trial name
- NCT00933478
- Testing
- Clay
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nova Scotia Health Authority
Eustachian Tube Dysfunction
Tubomanometry and EarPopper Devices for Eustachian Tube Function Testing
The Eustachian tube (ET) is a biological tube that links the middle ear to the back of the nose and throat. It has several functions, of which the most important is to maintain optimal middle-ear health.
- Trial name
- NCT03850197
- Testing
- EarPopper, Tympanometry, Tubomanometry
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Cuneyt M. Alper
Eustachian Tube Dysfunction
XprESS Eustachian Tube Dilation Study
Study to assess the safety and efficacy of the XprESS device for transnasal Eustachian tube dilation.
- Trial name
- NCT02391584
- Testing
- XprESS, Control
- Where
- 5 sites in United States
- Volunteers
- 60 people
- Sponsor
- Entellus Medical, Inc.
Otits Media With Effusion
Omega-3-Based Nutraceutical Supplementation as Adjunctive Therapy in Adults With Otitis Media With Effusion: A Multicenter, Double-Blind, Randomized Placebo-Controlled Trial
Brief Summary - OMENUTS Trial Otitis media with effusion (OME) is a condition in which fluid accumulates in the middle ear, causing conductive hearing loss, ear fullness, tinnitus, and Eustachian tube dysfunction.
- Trial name
- OMENUTS (NCT07721610)
- Testing
- Omega-3-based nutraceutical combination (Otoair Flogo), Bilastine 20 mg, Intranasal mometasone furoate spray
- Where
- Italy
- Volunteers
- 501 people
- Sponsor
- Isola Tiberina - Gemelli Isola Hospital, Rome, Italy
Ear Barotrauma, Middle Ear Disease
Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.
Eustachian tube dysfunction (ETD) and middle ear barotrauma (MEB) are common reported complications during hyperbaric oxygen treatment.
- Conditions
- Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury
- Trial name
- NCT04804098
- Testing
- Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
- Where
- United States
- Volunteers
- 1,553 people
- Sponsor
- Northwell Health
Otitis Media
Effect of Simethicone on Eustachian Tube Dysfunction
This study is designed to measure the effects of a chewable Simethicone tablet taken by mouth on middle-ear pressure in adults with a common cold and evidence of abnormal middle-ear pressure.
- Trial name
- NCT01312038
- Testing
- Simethicone
- Where
- United States
- Volunteers
- 25 people
- Sponsor
- University of Pittsburgh
Chronic Eustachian Salpingitis
Feasibility of Balloon Dilation of the Eustachian Tubes Under Local Anesthesia
The objective of this study is to demonstrate that balloon dilation of the Eustachian tubes can be done successfully for treatment of chronic dilatory Eustachian tube dysfunction under local anesthesia with acceptable patient…
- Trial name
- NCT04055714
- Testing
- Balloon dilation of the Eustachian tubes
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Piedmont Ear, Nose, Throat and Related Allergy, PC
Glue Ear, Tube Disorders Eustachian
Balloon Dilation of the Eustachian Tube in Children
Otitis media with effusion (OME) is very common in children and characterized by fluid in the middle ear without signs or symptoms of acute ear infection. Treatment options are tympanostomy tubes and/or adenoidectomy.
- Trial name
- NCT03499015
- Testing
- Balloon Eustachian Tuboplasty (BET)
- Where
- Austria
- Volunteers
- 50 people
- Sponsor
- Medical University of Vienna
Eustachian Tube Dysfunction
Balloon Dilation of the Eustachian Tube
In this study, patients with dysfunction of the eustachian tube will be included. They will be randomized to one of two treatment groups. 1. balloon dilation of the eustachian tube or 2.
- Trial name
- BDET (NCT05270031)
- Testing
- Balloon dilation of the eustachian tube
- Where
- Canada
- Volunteers
- 15 people
- Sponsor
- Sunnybrook Health Sciences Centre
Eustachian Tube Dysfunction
Effect of Novel Exhalational Delivery System With Fluticasone (EDS-FLU) on Eustachian Tube Dysfunction (ETD)
Intranasal nasal steroid sprays are the mainstay of treatment for chronic Eustachian tube dysfunction despite having little supportive evidence in the literature.
- Trial name
- NCT05275686
- Testing
- Fluticasone Propionate 93 MCG/1 ACTUATION Nasal Spray
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center