Clinical trials: Dyspnoea
Chronic Obstructive Pulmonary Disease (COPD)
Palliation of Dyspnea in Advanced Chronic Obstructive Pulmonary Disease (COPD)
Chronic Obstructive Pulmonary Disease (COPD) affects at least 750,000 Canadians and is currently the 4th leading cause of death in Canada.
- Trial name
- ROS-003 (NCT00982891)
- Testing
- Opioid (morphine sulphate) in low dose
- Where
- 3 sites in Canada
- Volunteers
- 45 people
- Sponsor
- Nova Scotia Health Authority
Heart Failure, Chronic Obstructive Pulmonary Disease
Triage of Reduced Exercise Tolerance in Frail Elderly
Background of the study: Many elderly suffer from reduced exercise tolerance or exercise induced shortness of breath (dyspnoea) which causes decreased mobility and restrictions in physical, psychological and social functioning.
- Trial name
- TREE (NCT01148719)
- Testing
- Index group
- Where
- Netherlands
- Volunteers
- 841 people
- Sponsor
- UMC Utrecht
Difficult Breathing
Accuracy of Ultrasound in Identification of Cricothyroid Membrane: A Randomized Clinical Trial
Routine surgery requires artificial breathing through the placement of a plastic tube into the patient's windpipe via mouth or nose. This tube serves as the source of providing oxygen to the patients during surgery.
- Trial name
- NCT01725828
- Testing
- Ultrasound, External Palpation
- Where
- 2 sites in Canada
- Volunteers
- 223 people
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Idiopathic Pulmonary Fibrosis
Beneficial Effects of Pulmonary Rehabilitation for Idiopathic Pulmonary Fibrosis
Idiopathic pulmonary fibrosis (IPF) is a devastating disease marked by progressive lung scarring leading to multiple life-altering sequelae.
- Trial name
- NCT01107028
- Testing
- Standard pulmonary rehabilitation program
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- National Jewish Health
Asthma
Efficacy of L-menthol on Breathlessness in Asthma
The purpose of this study is to assess the effect of L-menthol on breathlessness and exercise capacity in patients with Asthma.
- Trial name
- Ment-Astma (NCT07500974)
- Testing
- L-menthol
- Where
- 2 sites in Sweden
- Volunteers
- 20 people
- Sponsor
- Region Skane
Malignancy
Does Transcranial Magnetic Stimulation of the Cingulate Cortex Modulate the Perception of Dyspnoea?
The treatment we are studying is Transcranial Magnetic Stimulation (TMS). In TMS, an electromagnetic pulse is passed into the brain through a coil placed on the head.
- Trial name
- TMS (NCT00830921)
- Testing
- Transcranial Magnetic Stimulation
- Where
- United Kingdom
- Volunteers
- 12 people
- Sponsor
- University of Oxford
Dyspnea During Pregnancy, Physiological Changes in Pregnancy
Breathing Exercises Versus Incentive Spirometry in Third-Trimester Pregnancy
Shortness of breath (dyspnea) is commonly experienced during the third trimester of pregnancy due to physiological changes affecting the respiratory system.
- Conditions
- Dyspnea During Pregnancy, Physiological Changes in Pregnancy, Reduced Functional Endurance
- Trial name
- NCT07365163
- Testing
- Deep Breathing Exercises, Volume-Oriented Incentive Spirometry
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- University of Lahore
Dyspnea, Palliative Care
"Turkish Validation of the Respiratory Distress Observation Scale in Palliative Care"
Dyspnea is a subjective experience influenced by physiological, cognitive, behavioral, and sociocultural factors. While self-reported scales are commonly used to assess dyspnea severity, they are unsuitable for patients unable to…
- Conditions
- Dyspnea, Palliative Care, Reliability and Validity
- Trial name
- NCT06922292
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istinye University
Chronic Obstructive Pulmonary Disease Severe, Dyspnea
Study of the Cytokine Response During Exercise Dyspnea in Patients With Chronic Obstructive Pulmonary Disease (COPD). Effect of Body Composition
Dyspnea, more commonly known as breathlessness, is a symptom found in the majority of patients with chronic obstructive pulmonary disease (COPD), with a major impact on quality of life and mortality.
- Trial name
- CYTODINE (NCT06229509)
- Testing
- Effective noninvasive ventilation
- Where
- France
- Volunteers
- 26 people
- Sponsor
- University Hospital, Clermont-Ferrand
COPD
Imposed Pursed Lip Breathing at Rest and During Exercise In COPD
A randomized control trial was conducted at physiotherapy department of Pakistan Railway General Hospital from July 2017 to Dec 2017.
- Trial name
- NCT04138069
- Testing
- PLB+Aerobic Bicycling, Aerobic Bicycling
- Where
- Pakistan
- Volunteers
- 29 people
- Sponsor
- Riphah International University
Dyspnea, Hypercapnia
Venous Versus Arterial Blood Gas Sampling in Undifferentiated Emergency Patients
In the emergency department and intensive care unit, blood gas analysis is a crucial tool in the assessment of critically ill patients. Blood gas analysis is quick and repeatable at the bedside.
- Trial name
- NCT04409470
- Testing
- Blood gas sampling from artery and vein
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- University Hospital, Linkoeping
Respiratory Distress, Hypoglycemia
Observational Study of Infants Born at 34 to 37 Weeks of Gestation Until the Age of 1 Year
Late preterm infants are at an increased risk for short and long term morbidity (during the 1st year of life, their neurodevelopmental status may also be delayed as compared to infants born at term).
- Conditions
- Respiratory Distress, Hypoglycemia, Feeding Intolerance, Jaundice
- Trial name
- NCT00550069
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Cough, Dyspnea
Chest Ultrasound of ER Patients With Cough or SOB
Acute dyspnea (shortness of breath) is a common complaint for patients presenting to the Emergency Department (ED). The chest radiograph (CXR) has been the mainstay in evaluating patients with shortness of breath and often…
- Conditions
- Cough, Dyspnea, Wheezing
- Trial name
- NCT02269761
- Testing
- Nuvis Diagnostic Ultrasound System
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- University of Washington
Venous Thromboembolism (VTE), Exercise Therapy
Early Exercise-Based Rehabilitation in Patients Hospitalized for Acute Pulmonary Embolism
Up to half of patients with pulmonary embolism (PE) suffer from impaired quality of life, reduced physical capacity, and symptoms like shortness of breath even three months after diagnosis, despite standard treatment with…
- Conditions
- Venous Thromboembolism (VTE), Exercise Therapy, Quality of Life (QOL), Anxiety Depression
- Trial name
- RehabPE (NCT07143539)
- Testing
- Exercise-based rehabilitation program
- Where
- 6 sites in Switzerland
- Volunteers
- 160 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
COPD, Breathlessness
Reducing Breathlessness With Dronabinol in COPD Patients
This clinical trial examines whether Dronabinol, which contains the synthetic psychoactive compound tetrahydrocannabinol (THC), can alleviate severe breathlessness in patients with severe and very severe chronic obstructive…
- Conditions
- COPD, Breathlessness, Cannabis
- Trial name
- BONG (NCT06473701)
- Testing
- Dronabinol 2.5mg Capsule
- Where
- Denmark
- Volunteers
- 30 people
- Sponsor
- Vejle Hospital
Dyspnea
PAthwAy of Dyspneic patIent in Emergency in the North-east Region (North-East PArADIsE)
This is an observational retrospective multi-center study in patients managed for acute dyspnea by Emergency department medical team.
- Trial name
- N_E_PARADISE (NCT06235008)
- Where
- France
- Volunteers
- 75,000 people
- Sponsor
- Pr. Nicolas GIRERD
Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease
Move With Air: Exercise Training Study
The purpose of this study is to explore the role of a stream of cool air to the face, through fan-to-face therapy, as a novel adjunct non-pharmacological therapy to enable symptomatic adults with cardiopulmonary disease to…
- Conditions
- Chronic Obstructive Pulmonary Disease, Interstitial Lung Disease, Heart Failure
- Trial name
- NCT05646407
- Testing
- Honeywell HT-900 Turbo Force Air Circulator
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- McGill University
Dyspnea
Point-of-care Ultrasound Interest in Dyspneic Emergency Department Patients: an Observational Bicentric Study
The diagnostic value of Point-of-care ultrasound (POCUS) in emergency department (ED) dyspneic patients is shown by numerous studies with a limited number of patients. Recently, Zanobetti et al.
- Trial name
- ECUDYS (NCT04327882)
- Testing
- Point-of-care ultrasound
- Where
- 2 sites in France
- Volunteers
- 2,600 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Palliative Care, Dyspnea
The Effect of Acupressure on the Management of Dyspnea
Dyspnea can develop at any stage of the disease, but it is more common in the last period of life. Complementary and integrative methods used for dyspnea symptoms include acupuncture, acupressure, visualization techniques, herbal…
- Trial name
- NCT05884450
- Testing
- Acupressure
- Where
- Turkey (Türkiye)
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Istanbul Aydın University
Obesity, Metabolic Syndrome
Exercise Capacity and Dyspnea in Obese Patients With Metabolic Syndrome: Effects of Weight Loss
Dyspnea is a common complaint in obese patients. The mechanisms behind this dyspnea and the effects of weight loss on dyspnea are not completely understood.
- Trial name
- NCT03035149
- Testing
- Weight Management Program
- Where
- Canada
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of Ottawa
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