Clinical trials: Dyspnoea
Asthma
Comparison of Flutter and PEP Mask on Chest Clearance, Dyspnea in Elderly Asthmatic Patients
This study will be a Randomized controlled and will be conducted in Allied Hospital, Faisalabad. The study will be completed within the duration of 10 months. Convenience sampling study technique will be used to collect the data.
- Trial name
- NCT05618873
- Testing
- Flutter device, positive expiratory pressure mask
- Where
- Pakistan
- Volunteers
- 30 people
- Sponsor
- Riphah International University
Community-acquired Pneumonia, Dyspnea
Chest CT-scan for the Diagnosis of Community-acquired Pneumonia
Primary objective : to estimate impact of CT-scan on diagnostic for emergency department (ED) patients with suspected Community-acquired Pneumonia (CAP).
- Trial name
- PACSCAN (NCT01574066)
- Testing
- Chest CT-scan
- Where
- 4 sites in France
- Volunteers
- 339 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Inadequate or Impaired Respiratory Function, Diabetes
Effects of Respiratory Muscle Training in Obese Women
The objective of this study will be to evaluate the effects of inspiratory muscle training (IMT) on the physical fitness of obese women It is believed that the application of these exercises helps in the improvement of…
- Conditions
- Inadequate or Impaired Respiratory Function, Diabetes, Hypertension
- Trial name
- NCT03767556
- Testing
- Inspiratory muscle training
- Where
- Brazil
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Metodista de Piracicaba
COPD
Comparative Effects of BBT and Active Cycle of Breathing Technique on Dyspnea and Quality of Life in COPD
Comparative effects of Butyeko breathing technique and Active Cycle of Breathing technique on dyspnea and quality of life in patients with chronic obstructive pulmonary disease
- Trial name
- NCT05947253
- Testing
- Buyteko breathing technique, active cycle of breathing technique
- Where
- Pakistan
- Volunteers
- 40 people
- Sponsor
- Riphah International University
COVID-19
Effectiveness and Safety of Two Vitamin D3 Supplementation Regimens in Adults with Early-stage COVID-19
This study aimed to determine the effectiveness and safety of individualized vitamin D3 supplementation in adult patients with early-stage severe COVID-19.
- Trial name
- VDCOVID19ACUTE (NCT06585995)
- Testing
- vitamin D (cholecalciferol) supplementation
- Where
- Mexico
- Volunteers
- 216 people
- Sponsor
- Escuela Militar de Graduados de Sanidad, SEDENA
Dyspnea, Hypercapnia
Venous Versus Arterial Blood Gas Sampling in Undifferentiated Emergency Patients
In the emergency department and intensive care unit, blood gas analysis is a crucial tool in the assessment of critically ill patients. Blood gas analysis is quick and repeatable at the bedside.
- Trial name
- NCT04409470
- Testing
- Blood gas sampling from artery and vein
- Where
- Sweden
- Volunteers
- 250 people
- Sponsor
- University Hospital, Linkoeping
Dyspnea
Trial of a Breathlessness Intervention Service for Intractable Breathlessness
The aim of this study is to evaluate the impact of a Breathlessness Intervention Service (BIS) on the quality of life of patients and families affected by intractable breathlessness.
- Trial name
- NCT00678405
- Testing
- Breathlessness Intervention Service, Best supportive care (Standard Care)
- Where
- United Kingdom
- Volunteers
- 120 people
- Sponsor
- Cambridge University Hospitals NHS Foundation Trust
Pneumonia, Dyspnea
The Effects of Wintergreen Essential Oil Inhalation on Alleviating Dyspnea Among Patients With Pneumonia
Pneumonia is a major public health concern globally and domestically. Dyspnea experienced by hospitalized pneumonia patients often induces anxiety and psychological distress.
- Trial name
- NCT07894835
- Testing
- Sunflower oil inhalation, 1% Linalool inhalation, Wintergreen essential oil inhalation
- Where
- Taiwan
- Volunteers
- 84 people
- Sponsor
- Far Eastern Memorial Hospital
Congestive Heart Failure, Cardiomyopathy
FAST (Fluid Accumulation Status Trial)
Heart failure is a progressive disease that decreases the pumping action of the heart. This may cause a backup of fluid in the heart and may result in heart beat changes.
- Conditions
- Congestive Heart Failure, Cardiomyopathy, Dyspnea, Pulmonary Edema
- Trial name
- NCT00289276
- Testing
- Fluid Status Monitoring (OptiVol™)
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 156 people
- Sponsor
- Medtronic Cardiac Rhythm and Heart Failure
ADHF
Evaluation of the Diagnostic Value of the TPD System in Determining ADHF Causing Acute Dyspnea
The objective of this study is to evaluate Lung Doppler signals (LDS) among patients presenting to the emergency department with acute dyspnea, in order to determine the diagnostic value of this non-invasive method to…
- Trial name
- NCT03998410
- Testing
- Lung Doppler Signals
- Where
- 3 sites in United States
- Volunteers
- 130 people
- Sponsor
- Echosense Ltd.
COPD (Chronic Obstructive Pulmonary Disease), Acupuncture
Acupuncture for Persistent Dyspnea Despite Medical Treatment in COPD
This randomized controlled trial aims to evaluate the effectiveness of acupuncture as an adjunctive non-pharmacological therapy in patients with stable COPD who continue to experience dyspnea despite optimal medical treatment.
- Trial name
- COPD (NCT07058259)
- Testing
- Acupuncture, Standard COPD Pharmacological Therapy (LAMA + LABA or LAMA + LABA + ICS)
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Istanbul Medeniyet University
Asthma, Heart Failure
The General Breathing Record Study
This study will test the use of a new handheld device (called the N-Tidal C), that measures a person's tidal breath carbon dioxide, in diagnosing the cause of someone's breathlessness.
- Conditions
- Asthma, Heart Failure, Pneumonia, Motor Neuron Disease
- Trial name
- GBRS (NCT03356288)
- Where
- United Kingdom
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TidalSense
Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease
Clinical Stabilization of Hypercapnia: NIPPV v HVNI
This study will evaluate the ability of High Velocity Nasal Insufflation [HVNI] to effect ventilation and related physiologic responses in hypercapnic patients when compared to noninvasive positive pressure ventilation [NIPPV].
- Conditions
- Hypercapnic Respiratory Failure, Chronic Obstructive Pulmonary Disease, Dyspnea, Hypercapnic Acidosis
- Trial name
- HYPERACT (NCT04709562)
- Testing
- High Velocity Nasal Insufflation (HVNI), Noninvasive Positive Pressure Ventilation (NIPPV)
- Where
- 7 sites in United States
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Vapotherm, Inc.
Chronic Obstructive Pulmonary Disease (COPD)
Effect of Pursed-Lip Breathing With Different I:E Ratios on Respiratory Outcomes in COPD Patients
The goal of this clinical trial is to evaluate whether different inspiratory-expiratory (I:E) ratios in the pursed-lip breathing (PLB) technique can improve respiratory outcomes in patients with stable Chronic Obstructive…
- Trial name
- PLB I:E Ratio (NCT07573826)
- Testing
- Participants perform PLB with inspiratory-expiratory ratio 1:3 (2 seconds inspiration, 6 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:4 (2 seconds inspiration, 8 seconds expiration), Participants perform PLB with inspiratory-expiratory ratio 1:5 (2 seconds inspiration, 10 seconds expiration)
- Volunteers
- 122 people
- Sponsor
- Scholastica Fina Aryu Puspasari
Lung Diseases, Interstitial
INCHANGE - Nintedanib for Changes in Cough and Dyspnea in Patients Suffering From Chronic Fibrosing Interstitial Lung Disease With a Progressive Phenotype in Everyday Clinical Practice: a Real-world Evaluation
The primary objective of this study is to investigate the correlation between changes from baseline to 52 weeks in Forced Vital Capacity (FVC) [% pred.] and changes from baseline to 52 weeks in dyspnea score [points] or cough…
- Trial name
- NCT05151640
- Testing
- Nintedanib
- Where
- 31 sites in Bulgaria, Czechia and 3 more
- Volunteers
- 158 people
- Sponsor
- Boehringer Ingelheim
Covid19
Surgical Face Mask Effects in Patients With COVID-19
The use of personal protective equipment is mandatory for healthcare workers caring patient with COVID-19. To maximise the reduction of virus spread during clinical procedures involving the presence of healthcare workers, it is…
- Trial name
- NCT04689542
- Testing
- Sit-To-Stand test
- Where
- Belgium
- Volunteers
- 28 people
- Sponsor
- Cliniques universitaires Saint-Luc- Université Catholique de Louvain
Lung Neoplasm Malignant
Resistance Inspiratory Muscle Training for Patients With Thoracic Malignancies
A small-scale pilot randomized controlled trial conducted by the investigators demonstrated some preliminary evidence that inspiratory muscle training (IMT) could be a promising self-management method for alleviating…
- Trial name
- NCT03834116
- Testing
- Inspiratory muscle training
- Where
- China
- Volunteers
- 196 people
- Sponsor
- The Hong Kong Polytechnic University
CARDIOMYOPATHY
Combined Effect of Aerobic and Resistance Exercise in Non Ischemic Dilated Cardiomyopathy Patients
This study explores the effects of combined aerobic and resistance exercise in patients with non-ischemic dilated cardiomyopathy (NIDCM).
- Trial name
- NCT07062874
- Testing
- Combined Aerobic and Resistance Exercise, Aerobic Exercise Only
- Where
- Pakistan
- Volunteers
- 66 people
- Sponsor
- Riphah International University
Shoulder Arthroscopic Surgery
The Predictor of Respiratory Discomfort After the Shoulder Arthroscopic Surgery
The investigators applied upper airway ultrasonographic examination focusing the measurement of upper airway diameters in patients undergoing shoulder arthroscopic surgery to evaluate the change of upper airway anatomy before and…
- Trial name
- NCT01401205
- Testing
- upper airway ultrasonographic examination
- Where
- South Korea
- Volunteers
- 100 people
- Sponsor
- Samsung Medical Center
Dyspnea, Breathlessness
Breathlessness During Exercise: Experience and Memory
Breathlessness during exertion is a major limiting factor for patients' physical capacity and activity. Increased exertional breathlessness often results in impaired activity, spiraling deconditioning and further worsening of…
- Trial name
- NCT03458182
- Testing
- Added exercise
- Where
- Sweden
- Volunteers
- 92 people, healthy volunteers welcome
- Sponsor
- Magnus Ekström
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