Clinical trials: Dyspnoea
Fever, COPD
The Application of a Wireless Sensor Technology for Vital Statistics in CHILDREN AND ADULTS
The primary outcome for this project will be the development of a small, non-invasive wireless sensor that is linked to a conventional computer that can be used in health care for monitoring of acute and chronic health problems.
- Conditions
- Fever, COPD, Obesity, Congenital Heart Disease
- Trial name
- NCT01845506
- Testing
- Cardiorespiratory monitor, Wireless pressure sensor
- Where
- Canada
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Obstructive Pulmonary Disease
Effects of Active Cycle of Breathing Technique With and Without Acapella on Airway Clearance
We are conducting this study to check the effects of active cycle of breathing technique with or without acapella on airway clearance, dyspnea and pulmonary function test in COPD patients.
- Trial name
- NCT05618847
- Testing
- Acapella,ACBTS, ACBTs
- Where
- Pakistan
- Volunteers
- 54 people
- Sponsor
- Riphah International University
Dyspnea
Validation of an Observational Scale of Dyspnea in Non-communicating Patients in the ICU
Background : Dyspnea is common and severely impact mechanically ventilated patients outcomes in intensive care unit (ICU). Recognize, measure and treat dyspnea have become current major therapeutic challenge.
- Trial name
- DYS-NOC (NCT02801838)
- Testing
- Morphine
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
COPD
Effects of Exhalation Valve on the Lack of Air and Exercise Tolerance in Patients With COPD
The purpose of this study is to evaluate the effects of the application of Expiratory Positive Airway Pressure (EPAP) on Dynamic Hyperinflation, dyspnea and exercise tolerance in patients with Chronic Obstructive Pulmonary…
- Trial name
- NCT02566915
- Testing
- CPET submaximal with EPAP
- Where
- Brazil
- Volunteers
- 19 people
- Sponsor
- Hospital de Clinicas de Porto Alegre
Cancer
Non-invasive Ventilation in Terminally Ill Cancer Patients
The occurrence of acute respiratory failure (ARF) is often seen by oncologists as a terminal phase of the disease, this view being based on studies reporting limited survival at considerable costs in such patients.
- Trial name
- NCT00533143
- Testing
- non invasive ventilation (NIV)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS Azienda Ospedaliero-Universitaria di Bologna
Deep Venous Thrombosis, Pulmonary Embolism
FUVID Study: Functional Characterization of Children With Chronic Venous Thromboembolic Disease
This is a multi-center prospective cohort study of patients with first-episode deep venous thrombosis and pulmonary embolism.
- Trial name
- NCT04583878
- Testing
- Blood draw (Visit 1), Blood draw (Visits 2 and 3)
- Where
- 14 sites in United States
- Volunteers
- 115 people, healthy volunteers welcome
- Sponsor
- University of Texas Southwestern Medical Center
Alpha 1-antitrypsin Deficiency (AATD)
Screening for Alpha-1 Antitrypsin Deficiency in Patients With Airway Obstruction
Brief Summary: This study aims to find out if a genetic condition called Alpha-1 Antitrypsin Deficiency (AATD) is more common in people who have shortness of breath and signs of airway obstruction on their breathing tests.
- Trial name
- AATD-SAO (NCT07152834)
- Testing
- Blood Sampling
- Where
- Turkey (Türkiye)
- Volunteers
- 734 people, healthy volunteers welcome
- Sponsor
- Muğla Sıtkı Koçman University
Acute Respiratory Failure, Acute on Chronic Respiratory Failure
Treatment of Dyspnea in Do-not-intubate Patients
Patients with severe chronic diseases are often admitted to the hospital complaining of shortness of breath. Some of these patients decide that they do not want placement of a breathing tube in the windpipe to assist their…
- Conditions
- Acute Respiratory Failure, Acute on Chronic Respiratory Failure, Dyspnea
- Trial name
- NCT02114944
- Testing
- NIV, CPAP, Standard oxygen
- Where
- 2 sites in United States, Italy
- Volunteers
- 400 people
- Sponsor
- Tufts Medical Center
Lung Cancer
Brief Behavioral Intervention for Dyspnea in Patients With Advanced Lung Cancer
This research study is evaluating a behavioral intervention designed to help people with advanced lung cancer manage dyspnea (i.e., breathlessness or shortness-of-breath).
- Trial name
- NCT03089125
- Testing
- Dyspnea Intervention, Usual Care
- Where
- 2 sites in United States
- Volunteers
- 247 people
- Sponsor
- Massachusetts General Hospital
Pneumonia, Pulmonary Edema
Prehospital Use of Ultrasound in Undifferentiated Shortness of Breath
This is a pilot observational feasibility study of the ability of paramedics to assess thoracic ultrasound findings in the prehospital environment.
- Conditions
- Pneumonia, Pulmonary Edema, Dyspnea
- Trial name
- NCT02638649
- Testing
- Lung ultrasound, ultrasound
- Where
- 2 sites in United States
- Volunteers
- 69 people
- Sponsor
- Yale University
Respiratory Insufficiency
Nasal High Frequency Oscillatory Versus Nasal Intermittent Positive Pressure Ventilation in Neonate After Extubation
To evaluate the efficacy and safety of nasal high frequency oscillatory ventilation(NHFOV) in preterms with respiratory disease syndrome(RDS) after extubation.
- Trial name
- NCT02543125
- Testing
- NIPPV, NHFOV
- Volunteers
- 75 people
- Sponsor
- Gao WeiWei
Longitudinal Observational Study With 6 Months Follow-up
Longitudinal Observational Study for mIddle Term Follow-up Patients Admitted for Acute Dyspnea in TunIsia
The purpose of the SIDI study is to follow, few months after discharge from the hospital, the patients admitted to the 3 emergency departments in Tunisia for acute dyspnea and to determine the proportion and the factors favoring…
- Trial name
- SIDI (NCT04947358)
- Where
- Tunisia
- Volunteers
- 180 people
- Sponsor
- S Form Pharma
Hypoxic Respiratory Failure, Ventilators, Mechanical
Two Modes of Mechanical Ventilation for Intensive Care Patients With Low Blood Oxygen Due to Breathing Difficulties
The study examines individuals admitted to the intensive care unit due to breathing difficulties resulting in not getting enough oxygen into their bodies.
- Trial name
- NCT06140056
- Testing
- Airway pressure release ventilation, Volumen controlled mechanical ventilation
- Where
- 2 sites in Denmark
- Volunteers
- 45 people
- Sponsor
- University Hospital Bispebjerg and Frederiksberg
Work-related Illness
Respiratory and Physical Outcomes in Different Types of Office Workers
There are no studies in the literature reporting the posture, chest mobility, dyspnea, flexibility, quality of life and physical activity levels of emergency call center employees.
- Trial name
- NCT06216431
- Testing
- Physical Evaluations of individuals
- Where
- Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- Izmir Democracy University
Chronic Obstructive Pulmonary Disease
Resistance Training to Prehabilitate Patients With Chronic Obstructive Pulmonary Disease
Structural changes in skeletal muscles of patients with chronic obstructive pulmonary disease (COPD) have been linked to impaired muscle function, reduced exercise capacity, and increased mortality associated with this disease.
- Trial name
- NCT02860728
- Testing
- Individualized Resistance Training
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- University of British Columbia
Shortness of Breath, Respiratory Symptoms
Work of Breathing Assessment in Triage Scale
The proposed research study will be a prospective observational study designed to validate the Canadian Triage Assessment Scale (CTAS) in regard to work of breathing in patients in the emergency department.
- Conditions
- Shortness of Breath, Respiratory Symptoms, Cough, Difficulty Breathing
- Trial name
- NCT05479929
- Testing
- Canadian Triage Assessment Scale (CTAS)
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- CHRISTUS Health
Shortness of Breath Episode, Tachycardia
Verification of Prediction Algorithm
Prospective observational clinical study to verify an algorithm used to predict cardiopulmonary events in patients presenting to the emergency department.
- Conditions
- Shortness of Breath Episode, Tachycardia, Bradycardia, Difficulty Breathing
- Trial name
- VPAC (NCT02863666)
- Where
- 3 sites in United States, Belgium
- Volunteers
- 673 people
- Sponsor
- Zoll Medical Corporation
Copd, Dyspnea
Effects of Menthol on Dyspnoea in COPD Patients
Chronic obstructive pulmonary disease (COPD) is characterised by non-reversible bronchial obstruction associated with systemic disorders and comorbid factors.
- Conditions
- Copd, Dyspnea, Lung Diseases
- Trial name
- MEDiC (NCT03626519)
- Testing
- Test with Menthol
- Where
- 3 sites in France
- Volunteers
- 63 people
- Sponsor
- Groupe Hospitalier du Havre
Chronic Obstructive Pulmonary Disease
Effects of Respiratory Muscle Training and Respiratory Exercise in Exercise Tolerance, Performing Daily Life Activities and Quality of Life of Patients With Chronic Obstructive Pulmonary Disease
In patients with chronic obstructive pulmonary disease (COPD) breaths at an abnormally high lung volume causes the inspiratory muscle to operate at non-optimal lengths, which reduce their maximal contractile forces.
- Trial name
- NCT01510041
- Testing
- Inspiratory muscle training, Respiratory exercise
- Where
- Brazil
- Volunteers
- 40 people
- Sponsor
- Universidade Federal de Sao Carlos
Chronic Obstructive Pulmonary Disease
Effects of Inspiratory Muscle Training on Dyspnea in Subjects With Chronic Obstructive Pulmonary Disease
The purpose of this study is to determinate whether inspiratory muscle training (IMT) associated with a conventional respiratory rehabilitation program is more effective than a conventional respiratory rehabilitation program…
- Trial name
- IMT (NCT01545011)
- Testing
- Inspiratory muscle training
- Where
- 2 sites in France
- Volunteers
- 38 people
- Sponsor
- University Hospital, Brest
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