Clinical trials: Dystocia
Pregnancy, Uterine Contraction
Calcium Carbonate on Labor Induction
The investigators aim to evaluate the safety and efficacy of administering calcium carbonate to laboring participants undergoing labor inductions.
- Trial name
- NCT06352775
- Testing
- Calcium Carbonate
- Where
- United States
- Volunteers
- 250 people
- Sponsor
- Wake Forest University Health Sciences
Labour Dystocia
Oral Sodium Bicarbonate for the Prevention of Labour Dystocia
Sodium bicarbonate is often used by athletes to improve their muscle's ability to contract and power their activity. It works by decreasing the risk of lactic acid build-up, which causes cramping and fatigue.
- Trial name
- Labour-Aide (NCT06249061)
- Testing
- oral sodium bicarbonate
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Liz Darling
Labor Stage, First, Prolonged Labor
Maternal Maneuvers During Prolonged Labor
This pilot, randomized control trial will test whether or not a specific circuit of position changes improves maternal outcomes in cases of prolonged labor.
- Trial name
- CIRCUIT (NCT06636149)
- Testing
- Circuit of maternal position changes during labor
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- Washington University School of Medicine
Shoulder Dystocia
TelesDystocia: Tele-Support vs. Cognitive Aid in Simulated Shoulder Dystocia
Shoulder dystocia is an unpredictable, time-critical obstetric emergency requiring immediate recognition and rapid execution of established maneuvers.
- Trial name
- TelesDystocia (NCT07772102)
- Testing
- Remote Tele-Support, Cognitive Aid
- Where
- Austria
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Delivery Problem, Labor Pain
Effect of Virtual Reality for Pain Management During Intracervical Balloon Placement for Artificial Childbirth Induction
The labor induction concerns 22% of births in France. In the event of labor induction, in almost two thirds of cases, a cervical ripening method is used and the use of mechanical methods is observed for 8% of cervical ripening.
- Trial name
- VIRTUALMAG (NCT05155826)
- Testing
- Virtual Reality Headset
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Delivery Problem, Cervix; Pregnancy
Effects of Systematic Cervical Exam Training on Labor and Delivery Care
All physicians, nurses, and nurse midwives working on Labor and Delivery will be required to complete cervical exam simulation training.
- Conditions
- Delivery Problem, Cervix; Pregnancy, Pregnancy Related
- Trial name
- NCT04421768
- Testing
- cervical exam training
- Where
- United States
- Volunteers
- 1,125 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Labor Dystocia
Anticholinergics for Cervical Edema in Labor
The purpose of this study is to is to determine the clinical effectiveness of a single dose of intravenous (IV) medication for the prevention of labor arrest and cesarean delivery in primiparous women undergoing trial of labor.
- Trial name
- ACCEL (NCT06702670)
- Testing
- Treatment with Diphenhydramine, Usual Care
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- The University of Texas Health Science Center, Houston
Labor (Obstetrics)--Complications, Labor; Dyscoordinate
Biomarkers of Uterine Muscle Physiology
This observational study characterizes the relationship between amniotic fluid lactate and uterine electromyography during labor in healthy individuals at term planning a vaginal birth.
- Trial name
- BUMP (NCT04251702)
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Obstructed Labor
Use of Preoperative Sodium Bicarbonate Among Women With Obstructed Labor
The goal of this clinical trial is to determine a universal safe and effective dose of sodium bicarbonate for use among women with Obstructed labour to treat acidosis.
- Trial name
- SoBicOL-II (NCT06579690)
- Testing
- 8.4% sodium bicarbonate solution, 0.9% Normal Saline
- Where
- Uganda
- Volunteers
- 472 people
- Sponsor
- Busitema University
Shoulder Dystocia Training Using AI-supported Flipped Learning in Midwifery Education
Evalution of the Effectiveness of a Shoulder Dystocia Training Program Designed With Inverted Learning Supported by Generative Artificial Intelligence
With the ongoing digital transformation in health education, the importance of learner-centered and technology-integrated approaches has been increasing.
- Trial name
- NCT07514702
- Where
- Turkey (Türkiye)
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- Fenerbahce University
Humerus Fractures
Serum-Protein-Based Indices for the Progression of Fracture Healing and Nonunion
To define a serum protein-based diagnostic for the progression and failure of fracture healing, through the identification of a set of serum proteins that appear at early times of biological healing and show a specific…
- Trial name
- UNION (NCT05143476)
- Where
- United States
- Volunteers
- 45 people
- Sponsor
- Major Extremity Trauma Research Consortium
Blood Loss, Dysfunctional Labor
Cooling the Uterus in C-section After Dysfunctional Labor
The objective of the study is to demonstrate whether cooling the uterine smooth muscle during cesarean section (following delivery of the fetus) will promote better uterine contraction and involution resulting in lower blood…
- Conditions
- Blood Loss, Dysfunctional Labor, Uterine Atony
- Trial name
- NCT02910115
- Testing
- Cold laparotomy sponges, Pitocin
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Baylor Research Institute
Prolonged Labor, Labor Dystocia
Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour
The goal of this clinical trial is to learn if oral bicarbonate can treat prolonged labour in nulliparous women with prolonged labour.
- Trial name
- ProLabour (NCT07321379)
- Testing
- Sodium bicarbonate
- Where
- 3 sites in Denmark
- Volunteers
- 1,520 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Cesarean Section, Dystocia
The REDUCED Trial: REDucing the Utilization of CEsarean Sections for Dystocia
This project is a clustered randomized controlled trial of a knowledge translation intervention of new ACOG guidelines for the diagnosis of poor progress in labor.
- Trial name
- REDUCED (NCT02874443)
- Testing
- Knowledge Translation of labor management guidelines
- Where
- Canada
- Volunteers
- 88,918 people
- Sponsor
- University of Calgary
Shoulder Dystocia
Safety and Effectiveness of the Yaari Extractor for Management of Shoulder Dystocia
Prospective, multi-center, single arm with historical control, to verify the safety and effectiveness of the Yaari Extractor used by board certified or board eligible U.S. OB/GYN physicians in the management of shoulder dystocia.
- Trial name
- NCT05913609
- Testing
- Yaari Extractor
- Where
- 4 sites in United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- FetalEase Ltd.
Uterine Inertia, Dystocia
LXRs, Cholesterol Metabolism and Uterine Dystocia
Despite the fact that a link between cholesterol and the myometrium has been clearly established, no study investigating aspects of cholesterol metabolism and uterine dystocia currently exists.
- Trial name
- NCT01107158
- Testing
- Whole blood sampling
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Labor Dystocia, Labor Induction
Calcium Carbonate to Augment Labor Contractions
The investigators think that calcium carbonate can act as an assistive medication to improve contractions during labor.
- Conditions
- Labor Dystocia, Labor Induction, Labor Augmentation
- Trial name
- CALC (NCT06580782)
- Testing
- Calcium Carbonate 500 MG, Standard Dose Synthetic Pitocin
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Cesarean Delivery Affecting Fetus, Labor Dystocia
Early Diagnosis and Intervention for Fetal Malposition in Active Labor and Its Impact on Mode of Delivery
The goal of this randomized trial is to test if changing a person's position in labor can increase the chances of delivering their baby vaginally.
- Conditions
- Cesarean Delivery Affecting Fetus, Labor Dystocia, Labor Complication
- Trial name
- NCT05881629
- Testing
- Maternal position change to side-lying lateral with peanut ball, Free maternal position
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Women and Infants Hospital of Rhode Island
Shoulder Dystocia - Delivered
Management of Shoulder Dystocia in Flipped Learning
Flipped learning is an innovative learning method in midwifery education. Studies that apply this learning method together with shoulder dystocia training have not been found in the current literature.
- Trial name
- NCT06105268
- Testing
- flipped learning training group
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Karabuk University
Shoulder Dystocia, Simulation Based Medical Education
Simulation in Shoulder Dystocia Management
Shoulder dystocia is an unpredictable and unpredictable emergency obstetric condition that causes serious maternal and neonatal complications. Therefore, it requires immediate and effective intervention.
- Conditions
- Shoulder Dystocia, Simulation Based Medical Education, Midwifery
- Trial name
- NCT07009626
- Testing
- Computer-based high-validity birth simulator
- Where
- Turkey (Türkiye)
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- Sakarya University