Clinical trials: Dystonia, Cervical
Primary Cervical Dystonia
Segmental Muscle Vibration on Pain in Patients With Primary Cervical Dystonia
This pilot study aims to evaluate the effectiveness of Vibration Muscle Stimulation (VMS) in reducing pain and improving quality of life in patients with primary cervical dystonia (CD), a focal dystonia characterized by…
- Trial name
- VIBRA-DYSTONIA (NCT06748846)
- Testing
- Physiotherapy + Occupational therapy + Focal Muscle Vibration
- Where
- Italy
- Volunteers
- 28 people
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Cervical Dystonia
Safety and Effectiveness of Valbenazine as Adjunct Therapy to Botulinum Toxin Injections in Cervical Dystonia
The most common form of idiopathic dystonia is adult-onset cervical dystonia (CD), a focal form of dystonia affecting the muscles of the neck.
- Trial name
- NCT06771323
- Testing
- Valbenazine
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Virginia Commonwealth University
Idiopathic Cervical Dystonia
Factors Influencing Response to One BoNT-A Injection Cycle in Subjects Suffering From Idiopathic Cervical Dystonia
A post marketing, international, multicenter, observational, prospective, longitudinal study. The purpose of the study is to describe cervical dystonia sub-types with their injection protocols and response to BoNT-A.
- Trial name
- NCT00833196
- Where
- 39 sites in Australia, Belgium and 7 more
- Volunteers
- 404 people
- Sponsor
- Ipsen
Cervical Dystonia
Static Graviceptive Functions in Patients With Cervical Dystonia (CD)
The purpose of this experimental pilot study is to test the effect of normalization of the head position on the sense of balance at patients with cervical dystonia under routine botulinum toxin treatment.
- Trial name
- NCT01180270
- Where
- Austria
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Kirsten Elwischger
Idiopathic Cervical Dystonia
Targeting Methods of Botulinum Toxin Injections for Cervical Dystonia
Botulinum toxin injections are the treatment of choice for cervical dystonia. Even if this treatment is successful for most of the patients, partials or completes failures still remained.
- Trial name
- RINOCERAUS (NCT03946046)
- Testing
- Clinical targeting, Ultrasonography targeting
- Where
- France
- Volunteers
- 132 people
- Sponsor
- University Hospital, Lille
Dystonia
Neurophysiological Markers in Patients With Craniofacial Dystonia and Their Relatives
This study will use a technique called blink reflex to study and compare how the brain controls muscle movement in patients with craniofacial dystonia, their first-degree relatives, and healthy, normal volunteers.
- Trial name
- NCT00082615
- Where
- United States
- Volunteers
- 210 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Cervical Dystonia
Clinical Study of Ingrezza (Valbenazine) for the Treatment of Cervical Dystonia
Study of Ingrezza (Valbenazine) for the treatment of cervical dystonia.
- Trial name
- NCT05157100
- Testing
- Ingrezza Pill
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- The Orthopedic Foundation
Cervical Dystonia, Dystonia
Cholinergic Receptor Imaging in Dystonia
Background: Dystonia is a movement disorder in which a person s muscles contract on their own. This causes different parts of the body to twist or turn. The cause of this movement is unknown.
- Conditions
- Cervical Dystonia, Dystonia, Movement Disorder, Focal Dystonia
- Trial name
- NCT02689466
- Testing
- [18F]FP-TZTP
- Where
- United States
- Volunteers
- 31 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Primary Cervical Dystonia, Dystonia
rTMS and Botulinum Toxin in Primary Cervical Dystonia
Primary cervical dystonia (PCD) is the most common form of focal dystonia. PCD is frequently reported as a source of disability, decreased quality of life, and social stigma.
- Trial name
- NCT02542839
- Testing
- NeuroStar TMS therapy, Toronto Western Spasmodic Torticollis Rating Scale (TWSTRS), Craniocervical Dystonia Questionnaire (CDQ-24)
- Where
- 2 sites in United States
- Volunteers
- 9 people
- Sponsor
- University of Florida
Primary Cervical Dystonia, DYT 1 Dystonia
Neuroimaging of Dystonia
The main purpose of this study is to investigate primary cervical dystonia as compared to healthy control subjects and DYT 1 dystonia as compared to healthy control subjects by examining cognitive measures, physical measures, and…
- Trial name
- NID (NCT02046447)
- Testing
- Primary Cervical Dystonia (Trihexyphenidyl), Controls Primary Cervical Dystonia (Trihexyphenidyl), DYT 1 Dystonia (Healthy Control)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Florida
Cervical Dystonia
Open-label Extension Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia
The aim of this study is to assess longer term safety and effectiveness of Dysport®.
- Trial name
- NCT00288509
- Testing
- Botulinum toxin type A
- Where
- 18 sites in United States, Russia
- Volunteers
- 108 people
- Sponsor
- Ipsen
Cervical Dystonia
Randomized, Placebo-Controlled Study of AbobotulinumtoxinA (Dysport®) for the Treatment of Cervical Dystonia
The aim of this study is to demonstrate the effectiveness and safety of 500 units of Dysport manufactured at a new manufacturing facility in Europe.
- Trial name
- NCT00257660
- Testing
- Botulinum toxin type A
- Where
- 22 sites in United States, Russia
- Volunteers
- 116 people
- Sponsor
- Ipsen
Dystonia
Dystonia Coalition Projects
Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The primary focal dystonias are the most common type of dystonia and include Limb dystonias (like…
- Trial name
- NCT04156022
- Testing
- Dystonia Coalition is an observational study.
- Volunteers
- 2 people
- Sponsor
- University of Texas Southwestern Medical Center
Dystonia, Dystonic Disorder
Meditoxin® Treatment in Patients With Cervical Dystonia
To determine the efficacy and safety of Meditoxin in subjects with cervical dystonia compared with placebo (normal saline)
- Trial name
- NCT03232320
- Testing
- Meditoxin
- Where
- South Korea
- Volunteers
- 66 people
- Sponsor
- Medy-Tox
Isolated Cervical Dystonia
Accelerating TMS for Cervical Dystonia
This study aims to investigate the impact of accelerated transcranial magnetic stimulation (TMS) on brain function and behavior in patients with focal cervical dystonia.
- Trial name
- NCT06328114
- Testing
- Transcranial Magnetic Stimulation (TMS), trihexyphenidyl 10mg
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Duke University
Dystonia
The Dystonia Coalition Natural History and Biospecimen Repository for Isolated Dystonias
Dystonia is a disorder characterized by excessive involuntary contraction of muscles with repetitive and patterned movements. The isolated dystonias are the most common type of dystonia and include Limb dystonias (like writer's…
- Trial name
- DCP (NCT01373424)
- Where
- 42 sites in United States, Australia and 5 more
- Volunteers
- 3,265 people
- Sponsor
- Emory University
Isolated Cervical Dystonia
Cerebellar Transcranial Direct Current Stimulation (tDCS) in Patients With Isolated Cervical Dystonia (CD)
Cervical dystonia (CD) is a movement disorder characterized by involuntary muscle contractions of the neck, leading to abnormal head postures and movement, pain and impaired motor function.
- Trial name
- NCT07014384
- Testing
- Anodal and cathodal ctDCS
- Where
- Germany
- Volunteers
- 15 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Spasmodic Torticollis
Efficacy and Safety of Two Different Botulinum Toxin Type A Treatments for Moderate to Severe Cervical Dystonia
The purpose of this study is to compare two types of botulinum toxin type A to treat the involuntary muscle contractions in the neck
- Trial name
- NCT00432341
- Testing
- botulinum toxin type A
- Where
- 3 sites in Argentina, Australia and 1 more
- Volunteers
- 54 people
- Sponsor
- Allergan
Cervical Dystonia, Telemedicine
Telemedicine Follow-up for Patients With Cervical Dystonia Treated With Neurotoxin Injections
Many cervical dystonia (CD) patients are limited in their ability to travel to the clinic for follow-up in between injection visits.
- Trial name
- NCT03969537
- Testing
- Telemedicine follow-up visit
- Where
- United States
- Volunteers
- 27 people
- Sponsor
- Vanderbilt University Medical Center
Cervical Dystonia
tDCS in Cervical Dystonia
Dystonia is a devastating disorder defined by involuntary, sustained muscle contractions or abnormal postures that can affect any part of the body.
- Trial name
- NCT02180139
- Testing
- transcranial direct current stimulation
- Where
- United States
- Sponsor
- University of Minnesota