Clinical trials: ECG
Swimming Induced Pulmonary Edema (SIPE), Pulmonary Edema
Cardiac Function in Swimming-Induced Pulmonary Edema (SIPE)
Acute or chronic cardiac dysfunction could be a contributing factor to swimming-induced pulmonary edema (SIPE). Knowledge on cardiac function in SIPE is limited and recommendations for cardiac evaluation of patients with SIPE are…
- Conditions
- Swimming Induced Pulmonary Edema (SIPE), Pulmonary Edema, Lung Diseases, Heart Function Tests
- Trial name
- NCT05391737
- Testing
- Echocardiography, Electrocardiogram (ECG), Cardiac biomarkers
- Where
- Sweden
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Dalarna County Council, Sweden
Electrocardiography (ECG), Clinical Competence
Gamification Versus E-Learning for Electrocardiogram Education
This randomized controlled study aims to compare the effectiveness of a gamification educational method and an e-learning educational method for electrocardiogram (ECG) education.
- Trial name
- NCT07646236
- Testing
- Gamification Educational Method, E-learning Educational Method
- Where
- Taiwan
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- Taiwan Municipal An-Nan Hospital-China Medical University
Myocardial Infarction, Ischemia
Smartphone Twelve-Lead ECG Utility In ST-Elevation Myocardial Infarction II
AliveCor (www.alivecor.com) has developed several electrocardiogram (ECG) devices that interface with iOS and Android smartphones and tablets via various Kardia apps.
- Conditions
- Myocardial Infarction, Ischemia, Myocardial Ischemia, Heart Diseases
- Trial name
- STLEUISII (NCT06271577)
- Testing
- AliveCor 12-lead ECG
- Where
- 4 sites in United States, United Kingdom
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- AliveCor
Anaesthesia, Toxicity
Sensitivity of ECG on Detection of Three Different Intravascular Applied Test Doses of Bupivacaine and Epinephrine
The purpose of this prospective randomised study is to investigate electrocardiographic alterations after intravascular injection of three different test solutions of bupivacaine and epinephrine in anaesthetised children up to 16…
- Trial name
- NCT01091766
- Testing
- intravenous injection of test solution
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University Children's Hospital, Zurich
Artificial Intelligence, Electrocardiogram
Artificial Intelligence-enabled ECG Detection of Congenital Heart Disease in Children: a Novel Diagnostic Tool
Congenital heart disease (CHD) is the most common congenital disease in children. The early detection, diagnosis and treatment of CHD in children is of great significance to improve the prognosis and reduce the mortality of…
- Conditions
- Artificial Intelligence, Electrocardiogram, Deep Learning, Congenital Heart Disease in Children
- Trial name
- AI-ECG-CHD (NCT06383546)
- Where
- China
- Volunteers
- healthy volunteers welcome
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Fetal Monitoring, Non-invasive
Intrapartum Non-invasive Electrophysiological Monitoring
Conventional cardiotocography (CTG) has been used extensively for more than 50 years to monitor the fetal condition during labour, but since the rate of operative deliveries keeps rising, its ability to improve neonatal outcomes…
- Conditions
- Fetal Monitoring, Non-invasive, Cardiotocography, Electrocardiography
- Trial name
- NIEM-II (NCT06135961)
- Testing
- eCTG monitoring with the NFMS
- Where
- Netherlands
- Volunteers
- 3,471 people, healthy volunteers welcome
- Sponsor
- Maxima Medical Center
Heart Failure, Arrhythmias, Cardiac
Evaluation of ECG Transmission and AI Models Using Apple Watch ECGs and Symptoms Data Collected Using a Mayo iPhone App
The purpose of the study is to determine if the Electrocardiograms (ECGs) and symptoms data obtained from an Apple Watch and transmitted to Mayo Clinic are of sufficient quality to guide a person's care.
- Conditions
- Heart Failure, Arrhythmias, Cardiac, Health Care Utilization
- Trial name
- NCT05324566
- Where
- United States
- Volunteers
- 4,163 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Cardiac Arrhythmia, Cardiovascular Diseases
Autonomic Nerve Stimulation Using External Auditory Canal Electrodes
Purpose of the study This study aimed to investigate electrocardiogram measurement and subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes among healthy adult participants Study design…
- Trial name
- NCT04884607
- Testing
- subthreshold low-level autonomic nerve stimulation using external auditory canal electrodes
- Where
- South Korea
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Seoul National University Hospital
Electrocardiographic Signal Acquisition
Effects of Electrode Preparation on 12-Lead ECG R-Wave Amplitudes
This study evaluated whether different methods of preparing the skin before a standard 12-lead electrocardiogram (ECG) affect the recorded ECG wave amplitudes.
- Trial name
- NCT07787104
- Testing
- Electrode Preparation
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University
Metabolic Disease
AI Models for Non-invasive Glycaemic Event Detection Using ECG in Type 1 Diabetics
This observational study aims to recruit up to thirty T1DM patients from a diabetic outpatient clinic at the University Hospital Coventry and Warwickshire for a two-phase study.
- Trial name
- NCT05461144
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University Hospitals Coventry and Warwickshire NHS Trust
Coronary Artery Disease
Clinical Validation of PROPECG-TMT
This clinical validation evaluates the performances of physicians with and without learning with PROPECG-TMT assistance for screening coronary artery revascularization on TMT-ECG.
- Trial name
- NCT06624852
- Testing
- Screening for coronary artery revascularization based on TMT-ECG
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Yonsei University
Blood Pressure
Blood Pressure Sensor of Watch-type Device With ECG Technology
The ASUS Blood Pressure App "ASUS HealthConnect" is a software-only mobile medical application. It is designed to be compatible with ASUS VivoWatch SP watches and mobile phones.
- Trial name
- NCT05196048
- Testing
- No Intervention
- Where
- Taiwan
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- ASUSTek Computer INC.
Heart Failure
Home-based Outpatient Multicenter Evaluation Using Electrocardiogram (HOME-ECG)
This prospective multicenter observational study will validate the accuracy of a previously developed artificial intelligence-enabled single-lead electrocardiogram (AI-ECG) model for identifying low ejection fraction and other…
- Trial name
- HOME-ECG (NCT07488052)
- Testing
- Single-Lead ECG Acquisition [Apple Watch and QOCA ECG102D]
- Where
- Taiwan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- National Defense Medical Center, Taiwan
Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use
Food and Insulin Effect on QT/QTC Interval of ECG
Moxifloxacin is routinely used as a probe to confirm assay sensitivity in thorough electrocardiogram (ECG) studies. It has been shown that a meal shortens the QT interval, which may affect pharmacokinetics (PK) and/or…
- Conditions
- Effects of Different Meals on the QT/QTc Interval, Insulin and Oral Hypoglycemic [Antidiabetic] Drugs Causing Adverse Effects in Therapeutic Use, C-Peptide Effects on the QT/QTc Interval, Moxifloxacin ECG Profile in Fed and Fasted State
- Trial name
- C11035 (NCT01642485)
- Testing
- Moxifloxacin 400 mg fasted, FDA breakfast, Continental breakfast
- Where
- United Kingdom
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Richmond Pharmacology Limited
Tolerability of Wear of Electrode Pads
CAVA: Electrode Pad Appraisal Trial
This trial requires healthy volunteers to wear a selection of CE marked electrodes for up to 30 days. The results from this trial will determine which electrodes should be used with the CAVA device, which is a medical device for…
- Trial name
- CEPAT (NCT04012515)
- Testing
- Electrode Pads
- Where
- United Kingdom
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Julie Dawson
Healthy
Study to Investigate Safety With Special Emphasis on ECG Effects and Tolerability After Oral Doses of Dextromethorphan Hydrobromide Monohydrate in Healthy Male and Female Subjects
The primary objective of the current study is to investigate the safety with special emphasis on ECG effects, and tolerability of dextromethorphan hydrobromide monohydrate (2mg/mL syrup) in healthy male and female subjects…
- Trial name
- NCT02191176
- Testing
- Dextromethorphan syrup - low dose, Dextromethorphan syrup - high dose
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Healthy
Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans
The objectives of this study are to i) describe the absorption, distribution, metabolism and excretion (ADME) and pharmacokinetic parameters of selected dietary (poly)phenols in humans; and ii) to compare the ADME and…
- Trial name
- NCT03194620
- Testing
- Thearubigins, Theaflavins, Procyanidin Dimer B2 (DB2)
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of California, Davis
Safety, Peripheral Neuropathy
Xanamem™ in Healthy Elderly Subjects
Xanamem™ is being developed as a potential drug for Alzheimer's disease. This study drug has been designed to change the cortisol levels in the brain. Cortisol is a naturally occurring hormone in the body.
- Conditions
- Safety, Peripheral Neuropathy, Cortisol, Central Nervous System
- Trial name
- XanaHES (NCT03830762)
- Testing
- Xanamem
- Where
- Australia
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Actinogen Medical
Respiratory Rate, Pulse Oximetry
Validation of Respiration Rate Algorithms
Continuous accurate unobtrusive respiratory rate monitoring may lead to improved patient outcomes, as respiratory rate is thought to be a sensitive marker of patient deterioration.
- Trial name
- NCT01472133
- Testing
- Recording of 12 lead ECG, Recording of lying and standing blood pressure, Recording of chest wall movement
- Where
- United Kingdom
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- Guy's and St Thomas' NHS Foundation Trust
Healthy
CAEB071 Thorough QTc Study in Healthy Volunteers
This study has been designed in compliance with the ICH-E14 guideline 2005 to evaluate the QT/QTc interval prolongation and proarrhythmic potential for non-antiarrhythmic drugs.
- Trial name
- NCT01594255
- Testing
- sotrastaurin, Avelox
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Novartis Pharmaceuticals