Clinical trials: ECG
Healthy Volunteers
Cardiac Safety Evaluation of P03277
The study is a Phase I, Single center, Randomized, Cross-over Double-blind Placebo-controlled and Open-label Positive-controlled (moxifloxacin) in healthy volunteers.
- Trial name
- NCT03657264
- Testing
- P03277 0.1 mmol/kg, Moxifloxacin 400mg, NaCl 0.9%
- Where
- Belgium
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Guerbet
Brugada ECG Patterns, Brugada Syndrome (BrS)
Unmasking Concealed Arrhythmia Syndromes
This study seeks to evaluate whether using non-invasive electrocardiograph (ECG) techniques, including long term ECG monitoring with wearable ECGs, can improve the detection of concealed Brugada syndrome.
- Trial name
- UCAS (NCT06988189)
- Testing
- 12-lead ECG, Continuous long term ambulatory ECG monitoring, Ultra-high-frequency ECG
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Coronary Heart Disease
Myocardial Ischaemia After Exposure to Diesel Exhaust
Exposure to particulate air pollution is associated with increases in cardiovascular mortality and morbidity. The pathophysiological mechanisms underlying this observation are emerging, and exposure to particulate air pollution…
- Trial name
- MIDAS (NCT01661582)
- Testing
- CT/PET Myocardial Perfusion Imaging using O-15 water, Coronary blood flow measured by doppler echocardiography
- Where
- United Kingdom
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Cardiac Arrhythmia
True Continuous ECG Monitoring (TCEM Study)
The purpose of this study is to compare short term (up to 48 hours) traditional cardiac rhythm monitoring using a standard ambulatory Holter monitor versus long term (up to 14 days), continuous ambulatory cardiac rhythm…
- Trial name
- TCEM (NCT01559246)
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- iRhythm Technologies, Inc.
Heart Failure, Cardiac Resynchronization Therapy
Narrow QRS HF Patients Assessed by ECG Belt
The purpose of this study is to quantitate electrical dyssynchrony in heart failure (HF) patients with a narrow QRS complexes (≤ 130 ms) using the ECG Belt.
- Trial name
- NCT03367104
- Testing
- ECG Belt
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Heart Disease, Electrocardiograph
DigitHeart Echo Study
Eligible patients will be interviewed by research staff to explain the trial design and rationale. Written informed consent will be obtained from patients who voluntarily agree to participate.
- Conditions
- Heart Disease, Electrocardiograph, Echocardiography
- Trial name
- DigitHeart-SHD (NCT07558109)
- Testing
- echocardiography
- Where
- Hong Kong
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Electrocardiogram Electrode Site Reaction
The Efficacy of a Novel, Non-contact EKG in the NICU
This study aims to see how well a non-contact EKG compares to the EKG currently used in the special care nursery.
- Trial name
- NCT04269044
- Testing
- non-contact EKG
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Northwestern Medicine
Pregnancy
Fetal Electrocardiogram Extraction-Pilot Study
This is a pilot study utilizing trans-abdominal ECG and Doppler Ultrasounds to assess the feasibility of extracting fECGs in a volunteer population.
- Trial name
- NCT01681498
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Huntleigh Healthcare Ltd
Cardiovascular Diseases
Everbeat Ring ECG Clinical Concordance Study
This study is a cross-sectional observational study conducted in patients referred for routine ECG, to compare output from the everbeat finger-worn ECG device to standard of care (SOC) 12-lead electrocardiography.
- Trial name
- NCT05469542
- Testing
- Everbeat Ring
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Grektek Inc.
Arrhythmia, Atrial Fibrillation
Esophageal 3D Mapping System for Cardiac Arrhythmias
The aim of the study is to develop and validate a novel esophageal mapping system to improve the diagnostics of cardiac arrhythmias.
- Conditions
- Arrhythmia, Atrial Fibrillation, Atrial Flutter, Atrial Tachycardia
- Trial name
- esoECG-3D (NCT03365440)
- Testing
- esoECG-3D catheter
- Where
- Switzerland
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Long QT Syndrome, Cardiac Repolarization
Effect of Beta-blocker Therapy on QTc Response in Exercise and Recovery in Normal Subjects
Background. In congenital long QT syndrome type 1 (LQT1), episodes of ventricular tachycardia are usually triggered by exercise and can be prevented in most patients by beta-blocker therapy.
- Trial name
- NCT00588965
- Testing
- Propranolol LA
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- MetroHealth Medical Center
Infections, Respiratory Tract
Placebo and Moxifloxacin Controlled Cardiac Conduction Study of GSK2140944 in Healthy Volunteers
This is Phase I, 4-period, randomized, active-and placebo-controlled, double-blind crossover, single-dose study to evaluate the effects of a therapeutic (1000 milligram [mg]) and supratherapeutic (1800 mg) dose of GSK2140944 with…
- Trial name
- NCT02257398
- Testing
- GSK2140944, Moxifloxacin
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Spasticity
A Study to Define the ECG Effects of Tizanidine Compared to Placebo and the Positive Control, Moxifloxacin, in Healthy Men and Women Using a Blinded ECG Evaluator: A Thorough ECG Trial
This is a single-center, partial-blind, randomized, placebo-controlled, parallel design study with a nested crossover comparison to define the ECG effects of tizanidine compared to placebo and the positive control, moxifloxacin…
- Trial name
- TQT (NCT01839279)
- Testing
- Tizanidine, Moxifloxacin
- Where
- United States
- Volunteers
- 136 people, healthy volunteers welcome
- Sponsor
- Acorda Therapeutics
Subluxation
Simulated vs Genuine Manual Chiropractic Adjustments
Our primary aim with this trial is to measure participant blinding following two simulated/sham or genuine/real high velocity, low amplitude (HVLA) manual chiropractic adjustments to assess if participants are able to identify…
- Trial name
- SHA (NCT06931600)
- Testing
- Chiropractic adjustment
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Life University
Cardiovascular Disease
Implementation of Practice Standards for ECG Monitoring
The purpose of this study is to test the effect of implementing new practice standards for electrocardiographic (ECG) monitoring on nurses' knowledge and skills, quality of care, and patient outcomes.
- Trial name
- PULSE (NCT01269736)
- Testing
- Education
- Where
- 16 sites in United States, Canada and 1 more
- Volunteers
- 92,057 people, healthy volunteers welcome
- Sponsor
- Yale University
Acute Physiological Effects of Organic Guayusa Extract
Acute Effects of Organic Guayusa Extract
Guayusa extract is a caffeinated tea leaf unique blend of antioxidants and caffeine. It is marketed as an ingredient that can help support energy and performance with potential health-related benefits.
- Trial name
- NCT05928195
- Testing
- Acute Moderate-Dose Guayusa Extract Supplementation, Acute High-Dose Guayusa Extract Supplementation
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Nathaniel Jenkins
Magnetohydrodynamic Effect, Gradient-induced Voltages
12-lead ECG Recording During Cardiac MRI
This study aims to improve the quality of 12-lead ECG recordings taken during a cardiac MRI scan. The ECG is important for monitoring the heart's rhythm and for properly timing MRI image acquisition.
- Conditions
- Magnetohydrodynamic Effect, Gradient-induced Voltages, ECG Signal Quality, Measured Inside the MRI Bore
- Trial name
- C-MORE (NCT07456644)
- Testing
- MR-compatible 12-lead ECG recording system
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Calgary
Healthy
A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565111, and a Positive Control (Moxifloxacin)
The purpose of this study is to assess the effects on placebo-corrected change from baseline QT interval corrected for individual heart rate (QTcI) of JNJ-64565111 close to steady state on Day 26 and on electrocardiogram…
- Trial name
- NCT03606057
- Testing
- JNJ-64565111, Moxifloxacin
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Impaired Driving, Sleep Driving
Objective Assessment of the Effects of Shift Work on Drowsiness and Driving Impairment in Hospital Staff
The purpose of this protocol is to assess the risk of drowsy driving amongst shift workers using objective measures of drowsiness and driving performance in an instrumented research vehicle.
- Trial name
- NCT01672489
- Where
- United States
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
AI-driven, Self-directed Blood Pressure Monitoring
imPulse™ Tor System Self-Directed Cuffless Blood Pressure Monitoring
Self-measured, non-invasive accurate blood pressure monitoring continues to be a major challenge for automated vital sign measurement systems.
- Trial name
- NCT05386654
- Testing
- imPulse™ Tor System
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Level 42 AI, Inc.