Clinical trials: ECG
Healthy
A Study to Investigate the Effect of JNJ-64565111 on Cardiac Repolarization (Corrected QT Interval) Compared With Placebo in Healthy Adults: a Thorough ECG Study Employing Placebo, JNJ-64565111, and a Positive Control (Moxifloxacin)
The purpose of this study is to assess the effects on placebo-corrected change from baseline QT interval corrected for individual heart rate (QTcI) of JNJ-64565111 close to steady state on Day 26 and on electrocardiogram…
- Trial name
- NCT03606057
- Testing
- JNJ-64565111, Moxifloxacin
- Where
- United States
- Volunteers
- 188 people, healthy volunteers welcome
- Sponsor
- Janssen Research & Development, LLC
Hypertension
Cardiovascular Responses to Cold in Hypertension
Wintertime is associated with increased morbidity and mortality and a majority is related to cardiovascular causes, such as myocardial infarctions, heart failures, and strokes.
- Trial name
- ColdHTN (NCT02007031)
- Where
- 2 sites in Finland
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- University of Oulu
Atrial Fibrillation, Stroke
Systematic ECG Screening for Atrial Fibrillation Among 75 Year Old Subjects in the Region of Stockholm and Halland, Sweden
The purpose of this study is to determine whether screening for atrial fibrillation by intermittent ECG recording and initiation of anticoagulation treatment among high risk individuals is cost-effective and can lower the…
- Trial name
- NCT01593553
- Testing
- ECG screening for atrial fibrillation using intermittent ECG recorder
- Where
- Sweden
- Volunteers
- 7,173 people, healthy volunteers welcome
- Sponsor
- Karolinska University Hospital
ECG Electrode Site Reaction
Wireless ECG Body Sensor During Field Testing
Wireless body ECG sensor is a feasible solution for reliable and accurate long-term heart rhythm monitoring. However, there were no studies that delt with usability of this sensor in field testing.
- Trial name
- WECG (NCT04786509)
- Testing
- Field tests
- Where
- Serbia
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of Belgrade
Coronary Artery Disease
A Phase I Study in Healthy Volunteers to Evaluate the Safety of CardioPET™ in Detection of Coronary Artery Disease
Safety and dosimetry of CardioPET™ will be evaluated in normal healthy volunteers and CAD subjects both male and female between the ages of 50-85.
- Trial name
- NCT00413647
- Testing
- CardioPET
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Fluoropharma, Inc.
Electrocardiogram Repolarisation Abnormality, Gonococcal Infection
Thorough QT/QTC (TQT) Clinical Trial to Evaluate the Effect of Zoliflodacin on Cardiac Repolarization in Healthy Male and Female Subjects
The Phase I Thorough QT/QTc (TQT) study will be performed in a single center, the Vince \& Associates Clinical Research, Inc., clinical trials unit (CTU), in 72 healthy male or female subjects, aged 18 to 45 years inclusive, to…
- Trial name
- NCT03613649
- Testing
- AZD0914, Moxifloxacin
- Where
- United States
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Death, Sudden, Cardiac, Electrocardiogram QT Prolonged
Risk of Sudden Cardiac Death in UN Athletes
The detection of sudden cardiac death risk in athletes is a topic of great relevance in the field of sports physiotherapy and physical activity.
- Conditions
- Death, Sudden, Cardiac, Electrocardiogram QT Prolonged, Athlete Heart, Athletic Injuries
- Trial name
- Suddendeath (NCT06518252)
- Where
- Colombia
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Nacional de Colombia
Hypertension
A Safety Evaluation of ECG Intervals and Blood Pressure in Normal Healthy Volunteers After Use of Nebivolol, Atenolol, Moxifloxacin, or Placebo
Nebivolol is one of a class of drugs known as beta-blockers. These drugs are useful in the treatment of high blood pressure, angina, abnormal heart rhythms and following a heart attack.
- Trial name
- NCT00158093
- Testing
- Nebivolol, Atenolol, Moxifloxacin
- Where
- United States
- Volunteers
- 260 people, healthy volunteers welcome
- Sponsor
- Mylan Bertek Pharmaceuticals
ECG, Electrocardiography
Validation of Perin Health Patch ECG Monitoring Device Performance and Placement Accuracy
The goal of this clinical trial is to test how accurately and reliably a new chest-worn device called the Perin Health Patch measures heart rhythms (ECG) in adults aged 22 and older.
- Conditions
- ECG, Electrocardiography, Monitoring, Physiologic
- Trial name
- NCT07147920
- Testing
- Chest-Worn ECG Monitoring Device
- Where
- United States
- Volunteers
- 255 people, healthy volunteers welcome
- Sponsor
- Perin Health Devices
Pain, Postoperative
Wearable Electrocardiogram Monitoring Device and Smartphone Application in Perioperative Pain Management
This study aims to develop a wearable electrocardiograph monitoring device and smartphone application in perioperative pain management, also to evaluate relationship between postoperative pain and heart rate variability.
- Trial name
- NCT04686526
- Where
- China
- Volunteers
- 91 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College Hospital
Atrial Fibrillation
Combining Accelerometer, Gyroscope, Sound, Electrocardiography and Photoplethysmography Data in Cardiac Monitoring
The goal of this interventional clinical trial is to investigate whether combining photoplethysmography (PPG) signals with accelerometer (ACC), gyroscope (GYR), sound, and electrocardiography (ECG) derived smartphone data…
- Trial name
- CARDS-pilot (NCT06422468)
- Testing
- FibriCheck recordings
- Where
- Belgium
- Volunteers
- 125 people, healthy volunteers welcome
- Sponsor
- Qompium NV
Healthy Subjects
Evaluation of Dose-Dependent Repeated-Dose Neramexane Effects on Cardiac Repolarisation (QT/QTc Interval Duration): Electrocardiogram (ECG) Study in Healthy Adult Subjects
Primary: To assess the effects of ascending repeated-doses of oral [p.o.] neramexane at therapeutic and supra-therapeutic steady-state doses on cardiac repolarisation (QT/QTc interval) in healthy male and female subjects.
- Trial name
- NCT00978614
- Testing
- Neramexane
- Where
- Germany
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Merz Pharmaceuticals GmbH
Heart Failure, Cardiac Resynchronization Therapy
Narrow QRS HF Patients Assessed by ECG Belt
The purpose of this study is to quantitate electrical dyssynchrony in heart failure (HF) patients with a narrow QRS complexes (≤ 130 ms) using the ECG Belt.
- Trial name
- NCT03367104
- Testing
- ECG Belt
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Allina Health System
Emotion, Expressed
Study of Evoked Emotional Responses
Mental health and emotional awareness are a crucial need of the time. Changing lifestyles, stress, and anxiety are seen more commonly and affect many adults in the United States and other countries.
- Trial name
- NCT04044261
- Testing
- Emotion induction using video
- Where
- India
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Monsoon Design Studio LLC
Healthy, Asymptomatic
Normal Values of High Frequency ECG (HyperQ™) in Apparently Healthy Individuals and in Young and Masters Athletes
The main objective of this study is to investigate depolarization characteristics represented by changes in HyperQ in asymptomatic, apparently healthy athletic and non-athletic individuals.
- Conditions
- Healthy, Asymptomatic, Obesity
- Trial name
- NCT00847353
- Where
- Israel
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- BSP Biological Signal Processing Ltd.
Electrocardiography (ECG), Photoplethysmography
Synchronised ECG and PPG Data Collection for AI-based QT/QTc Reconstruction (ILECS-ECGPPG)
This observational study will collect synchronized photoplethysmography (PPG) and electrocardiogram (ECG) recordings from approximately 50 healthy adult volunteers.
- Conditions
- Electrocardiography (ECG), Photoplethysmography, Healthy Volunteers
- Trial name
- ILECS-ECGPPG (NCT07684807)
- Testing
- Corsano CardioWatch 287-2, VivaLNK wearable ECG patch
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Corsano Health B.V.
Lipid Profile,Blood Pressure
[Effects of Selected Statins on Cardiovascular Parameters in Healthy Volunteers]
This study is a Phase I randomized clinical trial aiming to investigate the short-term effects of three commonly prescribed statins i.e (Atorvastatin, Rosuvastatin, and Simvastatin) at different dose levels i.e lo,median and high…
- Trial name
- SBBU/IRC-25-31 (NCT07389304)
- Testing
- Rosuvastatin (5mg, 20mg, 40mg), Atorvastatin (10mg, 20mg, 40mg), Simvastatin (10mg, 20mg, 40m
- Where
- Pakistan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shaheed Benazir Bhutto University Sheringal Dir Upper
Atherosclerosis, Chronic Granulomatous Disease (CGD)
Non-Invasive Assessment of Atherosclerosis in Patients With CGD and Other Disorders of the Immune System
Background: Atherosclerosis, the arterial plaques or blockages that cause heart disease, develops in many people by the time they are in their mid-20s.
- Trial name
- NCT01063309
- Where
- United States
- Volunteers
- 156 people, healthy volunteers welcome
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
ST-T Segment Changes
ST-T Segment Changes in Emergency Physicians While on Duty
Preclinical emergency management is frequently associated with a combination of physical and psychological stress. This stress is known to lead to a broad variety of changes in the physiology even extending in the cardiovascular…
- Trial name
- NCT04003883
- Testing
- Holter ECG
- Where
- Austria
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Hepatitis C
TMC435-TiDP16-C117: The Effect of TMC435 on the Results of Electrocardiograms (Electric Recording of the Heart) in Healthy Volunteers
The purpose of this study is to evaluate the effect of TMC435 on the results of electrocardiograms (ECGs) in healthy volunteers. An electrocardiogram is an electric recording of the heart.
- Trial name
- NCT01269294
- Testing
- TMC435, Moxifloxacin
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Tibotec Pharmaceuticals, Ireland