Clinical trials: ED
Acute Pain
Protocolized vs Nonprotocolized Treatment of Adult ED Patients With Acute Severe Pain
Patients treated with protocolized pain management (1 mg of IV hydromorphone followed by an additional 1 mg IV hydromorphone if the patient wants more) will have better pain relief and no more adverse events than patients…
- Trial name
- NCT00627367
- Testing
- Hydromorphone, Nonprotocolized
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Erectile Dysfunction
Safety and Efficacy of the VERTICA® RF Device for the Treatment of ED
Adult subjects with mild to moderate and moderate ED who meet the study eligibility criteria will be enrolled in the study. The enrolled subjects will be randomized by a 1:1 ratio to receive the Active or Sham VERTICA® treatment.
- Trial name
- NCT06167733
- Testing
- VERTICA Active device
- Where
- 6 sites in United States
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- OHH-MED Medical Ltd
Sexually Transmitted Diseases
Clinical Utility of Rapid CT/NG Testing in the ED
The purpose of this study is to: 1. determine the clinical impact of rapid Chlamydia Trachomatis (CT), Neisseria Gonorrhoeae (NG) testing on antibiotic over and under treatment for CT/NG in women evaluated in the Emergency…
- Trial name
- NCT02200224
- Testing
- Rapid Testing
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Closed Multiple Fractures of Upper and Lower Limbs
Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine
the investigators assessed the effects of low-dose IV ketamine-midazolam versus morphine on pain control in trauma patients with closed limb fracture(s); and also compared the incidence of adverse events (mainly cardio pulmonary…
- Trial name
- NCT01807429
- Testing
- Ketamine-midazolam, Morphine
- Volunteers
- 236 people, healthy volunteers welcome
- Sponsor
- Isfahan University of Medical Sciences
Migraine Headaches, Nausea
Haldol/Diphenhydramine Versus Metoclopramide/Diphenhydramine for Treatment of Acute Headache in the ED: A RCT
Haloperidol is known to be a safe alternative medication to control difficult pain, and has been shown effective when compared to placebo for controlling headaches.
- Conditions
- Migraine Headaches, Nausea, Restlessness
- Trial name
- NCT02098499
- Testing
- Haloperidol, Metoclopramide 10mg, Diphenhydramine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- United States Naval Medical Center, Portsmouth
Lacerations, Abscess
Effectiveness of Nitrous Oxide in the ED
This will be a randomized control trial. All patients for whom an emergency provider determines that abscess drainage or laceration repair are necessary will be considered for enrollment.
- Trial name
- NCT02703233
- Testing
- Nitrous Oxide, Oxygen
- Volunteers
- healthy volunteers welcome
- Sponsor
- Christiana Care Health Services
Influenza, Human
Burden of Influenza at Emergency Department (ED) Level in European Countries
This study plans to conduct enhanced influenza surveillance at a hospital emergency department level independent of underlying influenza-like symptoms.
- Trial name
- NCT04244500
- Testing
- swab sampling
- Where
- Germany
- Volunteers
- 2,500 people, healthy volunteers welcome
- Sponsor
- University of Rostock
Emergencies, Diabetes Mellitus
Geography of ED Use and Population Health
The goal of this study is to create predictive models of emergency care and metrics for population health that can be used to analyze how events like hospital closures or disasters like Hurricane Sandy affect health care…
- Trial name
- NCT03254524
- Testing
- Statewide Planning and Research Cooperative System Database
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Simulation, Dizziness
Virtual Patient Education From Real Cases
Misdiagnosis of neurological conditions is common in healthcare settings, sometimes with devastating consequences. Most diagnostic errors result from failures in bedside diagnostic reasoning.
- Conditions
- Simulation, Dizziness, Vertigo, Stroke
- Trial name
- ViPER (NCT04553640)
- Testing
- Group A/Intervention Curriculum, Group B/Control Curriculum
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Coronary Artery Disease
Can CCTA Technicians Provide Accurate Interpretation of Findings in Patients Presenting to the ED in After Hours?
Coronary Computed Tomographic Angiography (CCTA) is emerging as the diagnostic test of choice in chest pain patients with low to intermediate probability of coronary artery disease (CAD).
- Trial name
- NCT03168269
- Testing
- Coronary Computed Tomographic Angiography (CCTA)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Jordan Collaborating Cardiology Group
Autism Spectrum Disorder
Satisfaction Rates Among Parents of Children With Autism in the ED
This study is a randomized controlled trial utilizing a patient-centered questionnaire distributed to parents of children with autism.
- Trial name
- ASD (NCT02675933)
- Testing
- Questionnaire
- Where
- United States
- Volunteers
- 63 people, healthy volunteers welcome
- Sponsor
- Seton Healthcare Family
Erectile Dysfunction
Differential Plasma MicroRNA Profiles in ED and Normal Erectile Function in Older Males
Erectile dysfunction (ED) is strongly associated with aging. With the rapidly expanding aging population and the increase in life expectancy, an increase in the prevalence of ED is expected in the years to come.
- Trial name
- NCT01830049
- Testing
- Take blood
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Nanjing Medical University
Emergency Department Visit, Odontalgia
An Emergency Department (ED) Provider Centered Intervention for Non-Traumatic Dental Condition Management (NTDC)
The overall objective of this proposal is to understand the barriers and facilitators to non-traumatic dental condition (NTDC) management in the emergency department (ED) through quantitative and qualitative methods.
- Trial name
- NCT06330207
- Testing
- Clinical decision support tool
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Florida
HIV Prevention, Pre-Exposure Prophylaxis (PrEP)
Starting HIV Prevention Medicine (PrEP) During an Emergency Department Visit With a Peer Navigator
The goal of this study is to learn whether adults who visit a hospital emergency department (ED) find it acceptable to start HIV pre-exposure prophylaxis (PrEP) during that same visit, with help from a peer navigator.
- Trial name
- RAPID Response (NCT07901101)
- Testing
- RAPID Response peer navigation, Emtricitabine/tenofovir disoproxil fumarate (F/TDF)
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of South Florida
Erectile Dysfunction, Premature Ejaculation
The Prevalence of Erectile Dysfunction (ED) and Premature Ejaculation (PE) in Poland
The first large population-based study to evaluate erectile dysfunction (ED) and premature ejaculation (PE) in Poland. The study objective is to assess the prevalence and bother of ED and PE in the representative group of male…
- Trial name
- ED POLAND (NCT05462171)
- Testing
- Questionnaires
- Where
- Poland
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Jagiellonian University
Aortic Dissection
Potential Diagnostic Biomarkers for Aortic Dissection in the Emergency Department
The goal of this observational study is to determine the utility of desmosine, D-dimer and aggrecan as early diagnostic biomarkers in aortic dissection.
- Trial name
- ADD-ED (NCT06065306)
- Where
- Hong Kong
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Stroke (CVA) or TIA, Diabetes
Risk Factors, Costs, and Impacts of ED Boarding
The goal of this observational study is to learn about the risk factors, costs, and operational impacts of emergency department boarding (patients admitted to the hospital but remaining in the emergency department awaiting…
- Conditions
- Stroke (CVA) or TIA, Diabetes, Asthma (Diagnosis), COPD (Chronic Obstructive Pulmonary Disease)
- Trial name
- NCT07532564
- Where
- United States
- Volunteers
- 30,486 people, healthy volunteers welcome
- Sponsor
- University of Maryland, Baltimore
Conscious Sedation, Distal Radius Fracture
IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures
The primary objective of this study is to evaluate the sedative, and analgesic effects of intranasal (IN) Dexmedetomidine (DEX) in children presenting to a Pediatric Emergency Department (PED) who undergo conscious sedation for…
- Trial name
- NCT03466242
- Testing
- Dexmedetomidine, Ketamine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Phoenix Children's Hospital
Asthma Exacerbation, Emergency Department
Efficacy of High-Dose Continuous Intravenous Magnesium Sulfate Infusion vs Standard Intravenous Magnesium Sulfate Therapy in Status Asthmaticus in the ED
The goal of this clinical is to compare treatment outcomes between high dose continuous IV Magnesium and standard therapy in the management of acute exacerbation of asthma in the emergency department.
- Conditions
- Asthma Exacerbation, Emergency Department, Magnesuim Sulfate, High Dose
- Trial name
- HIMAG-ED-STAT (NCT07795970)
- Testing
- ้High-dose Magnesium sulphate, standard-dose Magnesium Sulfate
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Thammasat University
Patient Outcome Assessment
Effect of Predictive Model on ED Physician Assessments of Patient Disposition
The goal of this study is to measure the impact of fairness-aware algorithms on physician predictions of ED patient admission. Using an experimentally validated machine learning model tuned for equitable outcomes, the…
- Trial name
- NCT06434220
- Testing
- Baseline model, Fairness-aware model
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Boston Children's Hospital