Clinical trials: ESWL
Kidney Calculi
Allopurinol Effect on MDA,NO,KIM-1 Urine Levels, RI and Renal Elastography in Kidney Stone Patients Post ESWL
Extracorporeal shock wave lithotripsy (ESWL) is accepted as the first treatment choice for most urinary stones. Still, it has adverse effects on the kidneys.
- Trial name
- NCT05414669
- Testing
- Allopurinol Tablet 300 mg, Control Group
- Where
- Indonesia
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- RSUP Prof. Dr. I.G.N.G. Ngoerahal
Nephrolithiasis
Strategies to Maximise Patient Comfort During ESWL
Extracorporeal shockwave lithotripsy is an outpatient treatment for patients with intrarenal calculi. Standard of care involves offering oral analgesia prior to commencing the treatment.
- Trial name
- NCT03379922
- Testing
- Stress balls, Headphones
- Where
- Ireland
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Cliodhna Browne
Kidney Calculi
Are There Protective Effects of Antioxidants, Calcium Channel Blocker and Angiotensin Receptor Blocker Against Extracorporeal Shockwaves Lithotripsy Induced Renal Injury?
This study will be conducted to evaluate the protective effects and mechanisms of antioxidants (vitamins A, C, E and Selenium), calcium channel blocker (Verapamil) and angiotensin receptor blocker (Lozartan) against shock wave…
- Trial name
- SWL (NCT01675362)
- Testing
- Antioxidant group, Calcium Channel Blockers, Angiotensin receptor blocker group
- Where
- Egypt
- Volunteers
- 160 people
- Sponsor
- Mansoura University
Nephrolithiasis
Early vs Delayed Extracorporeal Shock Wave Lithotripsy for Residual Stones After Percutaneous Nephrolithotomy
Residual renal stone fragments remain a common clinical issue following percutaneous nephrolithotomy (PCNL), with reported incidence ranging from 10% to 30%.
- Trial name
- NCT07523074
- Testing
- Extracorporeal shock wave lithotripsy (ESWL)
- Where
- Egypt
- Volunteers
- 476 people
- Sponsor
- Beni-Suef University
Urolithiasis
Retrolaminar Block Analgesia and Patient Comfort During Prone ESWL
The purpose of this prospective, observational study is to evaluate the effect of retrolaminar block (RLB) on patient comfort and analgesic effectiveness during extracorporeal shock wave lithotripsy (ESWL) procedures.
- Trial name
- NCT07177625
- Testing
- Retrolaminar block, Sedoanalgesia, No Intervention / None
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Elazıg Fethi Sekin Sehir Hastanesi
Ureteral Stones, Ureteral Calculi
Antibiotic Prophylaxis Before Shock Wave Lithotripsy
This is a two arm, double blind RCT comparing the use of a single dose ciprofloxacin prior to SWL to saline alone. The multicenter trial will be conducted with a pragmatic emphasis including both high volume and low volume sites…
- Conditions
- Ureteral Stones, Ureteral Calculi, Nephrolithiasis
- Trial name
- APPEAL (NCT03692715)
- Testing
- Ciprofloxacin
- Where
- 10 sites in Brazil, Canada and 7 more
- Volunteers
- 1,732 people
- Sponsor
- Clinical Urology and Epidemiology Working Group
Urinary Stone, Renal Injury
Urinary NGAL and KIM-1 After ESWL
The goal of this prospective observational study is to evaluate the effect of different time intervals between extracorporeal shock wave lithotripsy (ESWL) sessions on renal injury using urinary biomarkers in patients with…
- Trial name
- NCT07341269
- Testing
- No Interventions, No intervention
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Marmara University
Kidney Stone
Adjunct Inversion for Lower Pole Stone
This is a randomized controlled trial comparing extracorporeal shockwave lithotripsy (ESWL) with and without simultaneous adjunct controlled inversion therapy in the treatment of lower pole caliceal stone.
- Trial name
- NCT01852669
- Testing
- Inversion, Shock Wave Lithotripsy, Hydration
- Volunteers
- 140 people
- Sponsor
- Monash University
Pancreatitis, Chronic, Pancreatic Duct Stone
Aggressive Intravenous Hydration With Lactated Ringer's Solution for Prevention of Post-ESWL Pancreatitis
The goal of this clinical trial is to clarify whether aggressive intravenous hydration with lactated Ringer's solution could reduce the incidence of post-ESWL pancreatitis in patients with chronic pancreatitis.
- Trial name
- HYPER (NCT05772234)
- Testing
- Lactated ringers solution, normal saline
- Where
- China
- Volunteers
- 1,066 people
- Sponsor
- Changhai Hospital
Pancreatitis, Chronic
ESWL vs. Pancreatoscopy-guided Lithotripsy for Painful Chronic Calcific Pancreatitis
This is a multi-center randomized controlled trial comparing extracorporeal shock-wave lithotripsy (ESWL) with per-oral pancreatoscopy-guided lithotripsy (PPL) in the treatment of patients with chronic pancreatitis and refractory…
- Trial name
- NCT04115826
- Testing
- Per-oral Pancreatoscopy-guided Lithotripsy, Extracorporeal Shock-Wave Lithotripsy
- Where
- United States
- Volunteers
- 150 people
- Sponsor
- University of Colorado, Denver
Pancreatitis, Chronic
Optimal Timing of Endoscopic Intervention in the Treatment of Chronic Pancreatitis.
This study aims to determine the optimal timing of endoscopic intervention after extracorporeal shock wave lithotripsy(ESWL) of chronic pancreatitis with pancreatic stones.
- Trial name
- TEST (NCT05270434)
- Testing
- time interval between ESWL and ERCP is 12h, time interval between ESWL and ERCP is greater than 12h, morphine, buprenorphine, pethidine, tramaldol, metamizole and acetylsalicylacid (Analgesics)
- Where
- China
- Volunteers
- 220 people
- Sponsor
- Changhai Hospital
Kidney Stone
A Prospective Observational Comparison of SMP and ESWL for the Treatment of Renal Stones ≥20 mm in Children (IAU-04)
ESWL and PNL are the two treatment modalities for kidney stones greater than 20 mm in the pediatric population. ESWL is non-invasive, does not require anesthesia and inexpensive, but its success rate may be lower, and require…
- Trial name
- NCT04317443
- Testing
- Super-mini percutaneous nephrolithotomy (SMP), Extracorporeal Shock Wave Lithotripsy (ESWL)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- The International Alliance of Urolithiasis
Bile Duct Stenosis
Extracorporeal Shock Wave Lithotripsy Using Latest Lithotripter and Laser Lithotripsy for Difficult Bile Duct Stones
When conventional endoscopic treatment of bile duct stones is impossible or fails, advanced endoscopy assisted lithotripsy can be performed by electrohydraulic lithotripsy (EHL), laser lithotripsy, or extracorporeal shock wave…
- Trial name
- NCT05888077
- Testing
- ESWL_LL
- Volunteers
- 450 people
- Sponsor
- Asian Institute of Gastroenterology, India
Pediatric Urolithiasis
Shear Wave Elastography for Predicting Extracorporeal Shock Wave Lithotripsy Outcomes in Pediatric Renal Stones
This prospective study aims to evaluate the role of shear wave elastography (SWE) as a non-invasive and radiation-free tool for predicting the success of extracorporeal shock wave lithotripsy (ESWL) in pediatric patients with…
- Trial name
- SWE-ESWL (NCT07506031)
- Where
- Egypt
- Volunteers
- 110 people
- Sponsor
- Beni-Suef University
Urolithiasis, Extracorporeal Shock Wave Lithotripsy
Stress Ball Effects to Pain, Anxiety, Satisfaction and Treatment Continuity During ESWL
Extracorporeal shock wave lithotripsy (ESWL), a minimally invasive procedure, is used in the treatment of urolithiasis. The shock waves used in this procedure, which does not require any incision, cause pain in the superficial…
- Trial name
- NCT06846723
- Testing
- Stress ball
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people
- Sponsor
- Mersin University
Ureteric Stone
Effectiveness of LASER in Treatment of Ureteric Stones.
Ureteroscopic laser lithotripsy is becoming the most commonly utilized treatment for patients with ureteral stone. The Holmium: YAG laser is integral to the operation and is the preferred flexible intracorporeal lithotripsy.
- Trial name
- LASER (NCT06975488)
- Testing
- LASER Lithotripsy ( Fragmentation modality), LASER lithotripsy (Dusting Modality)
- Where
- Pakistan
- Volunteers
- 160 people
- Sponsor
- District Headquarters Teaching Hospital Sahiwal
Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy
COMPARİSON OF THE EFFECTS OF ULTRASOUND-GUİDED ERECTOR SPİNAE PLANE BLOCK AND INTRAMUSCULAR NONSTEROİDAL ANTİ-INFLAMMATORY DRUG ADMİNİSTRATİON ON INTRAOPERATİVE ANALGESİA AND PATİENT SATİSFACTİON DURİNG EXTRACORPOREAL SHOCK WAVE LİTHOTRİPSY
The aim of this study is to compare two ways of reducing pain during extracorporeal shock wave lithotripsy (ESWL), a non-invasive treatment that breaks up kidney and urinary stones with shock waves.
- Conditions
- Patient Satisfaction, Extracorporeal Shock Wave Lithotripsy, Erector Spinae Plane Block
- Trial name
- NCT07880535
- Testing
- Ultrasound-guided erector spinae plane block, Diclofenac Sodium (DCS)
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Sanliurfa Mehmet Akif Inan Education and Research Hospital
Shockwave Therapy
Role of Urine PH in Shock Wave Lithotripsy Outcomes in Renal Stone Disease
urolethiasis (kidney stones) is common globally, with recurrence in 50% of patients. Shock Wave Lithotripsy (SWL) is a minimally invasive treatment for stones < 2 cm.
- Trial name
- PHESWL (NCT07711028)
- Testing
- Shock Wave Iithotripsy, Extracorporeal shock wave lithotripsy
- Where
- Egypt
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- Benha University
Overactive Bladder, Botulinum Toxin
Delivery of Intravesical Botulinum Toxin A Using Low Energy Shock Waves in Treatment of Overactive Bladder: A Feasibility Study
We hypothesize that LESWs might temporarily increase urothelial permeability and facilitate delivery of intravesical botulinum toxin without the need for injection.
- Conditions
- Overactive Bladder, Botulinum Toxin, Intravesical, ESWL
- Trial name
- NCT03385460
- Testing
- ESWL BOTOX
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Choledocholithiasis, Common Bile Duct Calculi
SpyGlass Versus ESWL for Large Common Bile Duct Stones
Overall stone clearance with endoscopic retrograde cholangiopancreatography (ERCP) for choledocholithiasis is a big problem, especially for stones with a diameter greater than 3cm.
- Trial name
- NCT05186350
- Testing
- ERCP+ SpyGlass, ESWL+ ERCP
- Where
- China
- Volunteers
- 65 people
- Sponsor
- First People's Hospital of Hangzhou