Clinical trials: EUS
Disorders of Gallbladder, Disorders of Biliary Tract
EUS-Guided Rendezvous or Direct Interventions Versus Advanced ERCP Techniques for Biliary Access and Therapy
The purpose of this study is to prospectively compare the efficacy of endoscopic ultrasound-guided biliary interventions (EUS-rendezvous or direct EUS-guided therapy) to that of advanced ERCP cannulation techniques in the setting…
- Trial name
- NCT01678326
- Testing
- EUS-Rendezvous or direct intervention, Advanced ERCP Biliary Access Techniques
- Where
- United States
- Volunteers
- 226 people
- Sponsor
- California Pacific Medical Center Research Institute
Pancreatic Adenocarcinoma, Pancreatic Cancer
Eus-guided Cryothermal Ablation in Stage III Pancreatic Adenocarcinoma
Pancreatic cancer represents the 11th most commonly diagnosed cancer in men and 9th in women, being the third leading cause of cancer-related death in the Western countries.
- Conditions
- Pancreatic Adenocarcinoma, Pancreatic Cancer, Pancreas Neoplasm
- Trial name
- NCT03649035
- Testing
- HTP treatment
- Where
- Italy
- Sponsor
- Istituto Clinico Humanitas
Portal Hypertension
Direct Portal Pressure Measurement Via Endoscopic Ultrasound in Advanced Chronic Liver Disease (EVADIPP)
A minimally invasive procedure to directly assess portal pressure gradient under endoscopic ultrasound guidance (EUS-PPG) has become available and initial data have proved the technique to be safe.
- Trial name
- EVADIPP (NCT06266260)
- Testing
- EUS PPG measurement
- Where
- Italy
- Volunteers
- 50 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Sarcoidosis, Endosonography
EBUS vs EUS-B for Diagnosing Sarcoidosis
Rationale: Endosonography with mediastinal/ hilar nodal sampling is the test of choice to diagnose sarcoidosis stage I and II - in case tissue verification of noncaseating granulomas is indicated.
- Trial name
- NCT02540694
- Testing
- Endosonography
- Where
- Netherlands
- Volunteers
- 350 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pancreatic Cancer
Endoscopic Ultrasound Guided Fine Needle Biopsy (EUS-FNB-SC) Using a Novel Fork Needle
This is a clinical trial to compare two needles used in biopsy techniques to acquire tissue from pancreatic cancer. The hypothesis is that the tissue yield, as measured by tumor DNA and cellular material is superior for Flexible…
- Trial name
- NCT02678442
- Testing
- Fine Needle Biopsy (FNB), Fine Needle Aspiration (FNA)
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Mayo Clinic
Leiomyoma, GIST
Detective Flow Imaging Endoscopic Ultrasonography in Subepithelial Lesions
Gastrointestinal stromal tumors (GIST) are the most common malignant subepithelial lesions (SELs) found in the gastrointestinal tract.
- Trial name
- NCT05474794
- Testing
- DFI-EUS, CE-EUS
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreatic Neoplasm
Comparison of EUS-FNB Biopsy Techniques of Solid Pancreatic Lesions
Patients with a diagnosis of solid pancreatic lesions evidenced by imaging studies (CT, MRI) and who undergo endoscopic ultrasound-guided biopsy will be selected.
- Trial name
- NCT04843956
- Testing
- Endoscopic ultrasound-guided biopsy
- Where
- Mexico
- Volunteers
- 41 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Gastrointestinal Subepithelial Tumors
EUS-guided Fine Needle Aspiration (EUS-FNA) Versus EUS-guided Fine Needle Biopsy (EUS-FNB) for Diagnosis of Subepithelial Tumors
Background: Preoperative pathologic diagnosis of subepithelial tumor (SET) can improve clinical decision making. Although EUS-guided fine needle aspiration (FNA) is currently considered the standard method for sampling SET, its…
- Trial name
- NCT02943837
- Testing
- Device: 22G FNA needle, Device: 20G FNB needle
- Sponsor
- Asan Medical Center
Biopsy, Fine-Needle, Endosonography
Impact of Suction in the EUS-guided Fine Needle Biopsy of Solid Pancreatic Lesions
Tissue acquisition by Endoscopic Ultrasound (EUS) has become a modality of diagnosis and clinical orientation for several diseases.
- Conditions
- Biopsy, Fine-Needle, Endosonography, Pancreatic Neoplasm
- Trial name
- NCT04164017
- Testing
- EUS-guided FNB with Syringe Suction, EUS-guided FNB without Syringe Suction
- Where
- Portugal
- Volunteers
- 100 people
- Sponsor
- Centro Hospitalar De São João, E.P.E.
Neoplasms, Infection
A Multi-center, Prospective, Single-blind, Controlled Trial Comparing Diagnostic Value of Different EUS-FNA Techniques
The aim of this study is to compare endoscopic ultrasound guided-fine needle aspiration (EUS-FNA) with a standard 22-gauge needle using "standard suction", "slow-pull" and "wet suction" for thoracic/abdominal solid/solid-cystic…
- Conditions
- Neoplasms, Infection, Inflammation, Lymphoma
- Trial name
- EUS-FNA (NCT03674710)
- Testing
- Standard suction, slow-pull, wet suction, Standard suction, wet suction, slow-pull, Slow-pull, standard suction, wet suction
- Where
- 4 sites in China
- Volunteers
- 300 people
- Sponsor
- Shanghai Zhongshan Hospital
Pancreatic Diseases
The 22G Franseen Needle Combined With Different Aspiration Techniques for Endoscopic Ultrasound-guided Fine-needle Biopsy
The goal of this clinical study is to compare the tissue adequacy, cellularity, blood contamination, accuracy, sensitivity, specificity of the 22G Franseen needle combined with three different suction techniques (dry-suction…
- Trial name
- NCT07023549
- Testing
- ABC, ACB, BAC
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Changhai Hospital
Liver Diseases, Liver Fibrosis
Prospective Single Centre Observational Study to Compare the Diagnostic Yield of Different Modalities of Liver Biopsy
The goal of this study is to learn about endoscopic ultrasound(EUS) guided liver biopsy and how this compares to traditional methods of obtaining liver biopsy samples, in patients with liver disease.
- Trial name
- NCT05912179
- Testing
- Liver biopsy - percutaneous, Liver biopsy - transjugular, liver biopsy - EUS guided
- Where
- United Kingdom
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Nottingham University Hospitals NHS Trust
Acute Cholecystitis
Evaluation of a Protocol for Multidisciplinary Management of Acute Cholecystitis.
Acute cholecystitis is a complex disease and its management is sometimes controversial. Two main factors contribute to its complexity: the patient's surgical risk and the possibility of concomitant choledocholithiasis.
- Trial name
- NCT04543578
- Where
- Spain
- Volunteers
- 600 people
- Sponsor
- Fundacion Miguel Servet
Endoscopic Ultrasonography, Sedation
End-Tidal Carbon Dioxide Monitoring Device for Sedation During Endoscopic Ultrasonography
To meet the needs of both operators and patients, moderate and deep sedation has been widely used in digestive endoscopy, which is invasive and painful. With its pleasant effects, sedation has complications nevertheless.
- Conditions
- Endoscopic Ultrasonography, Sedation, Monitoring
- Trial name
- NCT04549623
- Testing
- Novel end-tidal CO2 monitoring device, SpO2 and respiratory motion monitoring
- Where
- China
- Volunteers
- 480 people
- Sponsor
- Changhai Hospital
Pancreatic Cyst, Pancreatitis, Acute
Rectal Indomethacin to Prevent Acute Pancreatitis in EUS-FNA of Pancreatic Cysts
The aim of this randomized trial is to compare the rate of post-procedure pancreatitis in patients undergoing EUS-FNA of pancreatic cysts; patients will receive either a single dose of indomethacin or placebo administered…
- Trial name
- NCT05572788
- Testing
- EUS-guided fine needle aspiration of pancreatic cysts
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Orlando Health, Inc.
Pancreatic Cancer
EUS RFA for Treatment of Pancreatic Ductal Adenocarcinoma (PDAC)
This is a single arm study in the treatment of pancreatic ductal adenocarcinoma (PDAC). The investigators propose to test the tolerability of chemotherapy plus endoscopic ultrasound-guided radiofrequency ablation (EUS-RFA) using…
- Trial name
- NCT05723107
- Testing
- Chemotherapy, Endoscopic Ultrasound-Guided Radiofrequency Ablation (EUS-RFA)
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- NYU Langone Health
Mediastinum
EBUS-TBNA vs EUS-B-FNA for Needle Aspiration of Mediastinal Lesions
Endobronchial Ultrasound Guided Transbronchial Needle aspiration (EBUS-TBNA) is a firmly established modality for diagnostic evaluation of mediastinal lesions.
- Trial name
- TEAM (NCT02704078)
- Testing
- EBUS-TBNA, EUS-B-FNA
- Where
- India
- Volunteers
- 100 people
- Sponsor
- All India Institute of Medical Sciences
Pancreatic Space Occupying
Research on the Value of Genomics Research Based on Ultrasound Endoscopic Biopsy in the Differential Diagnosis and Prognostic Evaluation of Pancreatic Occupancy
To clarify the value of genomic testing in the clinical diagnosis or prognosis of pancreatic space occupation, provide a basis for the selection of clinical diagnosis methods for pancreatic space occupation, optimize clinical…
- Trial name
- NCT04986215
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Changhai Hospital
GIST
Evaluation of a New EUS-guided Needle (ProCore) Comparing to EUS-TCB Needle (Quick-Core)
The purpose of this study is to evaluate a new EUS-guided biopsy needle (ProCore®) comparing it to conventional EUS-TCB needle (Quick-Core®) in the diagnosis of your suspicious disorder.
- Trial name
- NCT01768325
- Testing
- EUS-TCB needle (QuickCore) standard of care, EUS-Guided biopsy needle (ProCore)
- Where
- United States
- Volunteers
- 85 people
- Sponsor
- Indiana University
Pancreatic Cancer
SurePathTM Liquid-based Cytology and Conventional Smear Cytology in Pancreatic Lesions
The SurePathTM has been approved by the FDA since 1997. Currently, the SurePathTM is used for endometrial cells, body fluids, bronchoscopy aspirates, and thyroid fine needle aspirates.
- Trial name
- NCT03606148
- Testing
- SurePathTM
- Where
- South Korea
- Volunteers
- 170 people
- Sponsor
- Seoul National University Hospital