Clinical trials: EUS
Liver Diseases
Wet Heparin for Obtaining Liver Tissue for EUS Guided Liver Biopsy
Since its inception, endoscopic ultrasound with fine needle aspiration (EUS-FNA) has proven a valuable diagnostic and prognostic tool for evaluating a diverse number of pathologies.
- Trial name
- NCT03103997
- Testing
- EUS-guided liver biopsy
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Geisinger Clinic
Patients Indicated for Periampullary or Pancreaticobiliary Examination
Study for the Detection of Duodenal Papilla Using Capsule Endoscopy and Comparison of Images With EUS/ERCP Procedure.
This observational Non-Significant Risk (NSR) Study will be used to assess the ability of CapsoCam® Plus (SV-3) capsule endoscope to detect the duodenal papilla and visualize pathology or abnormalities in the periampullary area…
- Trial name
- NCT03685903
- Testing
- CapsoCam® Plus (SV-3) capsule endoscope
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Capso Vision, Inc.
Portal Vein Thrombosis, Portal Hypertension Related to Cirrhosis
Endoscopic Ultrasound-guided Measurement of Portal Vein Pressure Gradient
This study aims to evaluate the accuracy and safety of a novel endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) measurement technique in 42 adults with liver cirrhosis and portal vein thrombosis (blood clots in the…
- Trial name
- NCT07062289
- Testing
- endoscopic ultrasound-guided portal pressure gradient
- Volunteers
- 42 people
- Sponsor
- Zhejiang University
Pancreatic Masses, Lymph Nodes
Comparing a 25G EUS Fine Needle Aspiration (FNA) Device With a 20G EUS
The aim of this study is to compare the diagnostic accuracy of two EUS-guided tissue acquisition devices; the 25G Echotip Ultra Fine Needle Aspiration (FNA) device and the 20G Echotip ProCore Fine Needle Biopsy (FNB) device.
- Trial name
- ASPRO (NCT02167074)
- Testing
- 25G FNA needle, 20G ProCore FNB needle
- Where
- 13 sites in United States, Australia and 8 more
- Volunteers
- 615 people
- Sponsor
- Foundation for Liver Research
Pancreatic Diseases
The 22G Trident Needle Combined With Different Aspiration Techniques for Endoscopic Ultrasound-guided Fine-needle Biopsy
The goal of this clinical study is to compare the tissue adequacy, cellularity, blood contamination, accuracy, sensitivity, specificity of the 22G Trident needle combined with three different aspiration techniques (dry-suction…
- Trial name
- NCT07023562
- Testing
- ABC suction sequence, ACB suction sequence, BAC suction sequence
- Where
- China
- Volunteers
- 270 people
- Sponsor
- Changhai Hospital
Gastrointestinal Diseases
Artificial Intelligence vs Endoscopist Identification in EUS Normal Anatomy
Endoscopic ultrasound (EUS) visual impression is operator-dependant and can hinder diagnostic accuracy, especially in less experienced endoscopists.
- Trial name
- NCT06279546
- Testing
- Detection of structures
- Where
- Ecuador
- Volunteers
- 30 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Pancreatic Cancer, Pancreatitis
Validation of Joint-AI in Diagnosing Pancreatic Solid Lesions
This clinical trial aims to learn if a multimodal artificial intelligence (AI) model can enhance the diagnosis of pancreatic solid lesions. The main questions it aims to answer are: 1.
- Conditions
- Pancreatic Cancer, Pancreatitis, Pancreatic Neuroendocine Neoplasms (pNETs), Autoimmune Pancreatitis
- Trial name
- NCT06753318
- Testing
- The assistance of the Joint-AI model, The assistance of the interpretable Joint-AI model
- Where
- China
- Volunteers
- 716 people
- Sponsor
- Huazhong University of Science and Technology
Pancreas Neoplasm, Pancreas Cancer
Novel Crown-cut Biopsy Needle (FNB) vs Standard Aspiration Needle (FNA) for EUS-guided Diagnosis of SPLs
The aim of this study is to compare tissue quality and molecular yield between a novel crown-cut biopsy needle (FNB) and a standard aspiration needle (FNA) for EUS-guided diagnosis of solid pancreatic lesions.
- Trial name
- NCT04687410
- Testing
- ProControl, MediGlobe, TopGain, Medi-Globe
- Where
- Denmark
- Volunteers
- 68 people
- Sponsor
- Peter Vilmann MD, DSc, HC, FASGE
Gastrointestinal Tract, Gastrointestinal Stromal Tumor
Feasibility and Yield of a New 20 G ProCore Needle With Coiled Sheath in the Gastrointestinal Subepithelial Tumors
The exact incidence of subepithelial tumors (SETs) in the gastrointestinal (GI) tract is unknown, but the prevalence of gastric SETs detected during routine esophagogastroduodenoscopy is 0.36%.
- Trial name
- NCT02884154
- Testing
- Echotip ProCoreⓇ HD Ultrasound Biopsy Needle
- Volunteers
- 39 people
- Sponsor
- Pusan National University Hospital
Gastric Outlet Obstruction
Clinical Trial of EPASS With Hot AXIOS System
A prospective, multi-center, single-arm study for unresectable malignant gastric outlet obstruction with EUS-guided double-balloon-occluded gastrojejunostomy bypass (EPASS)
- Trial name
- PASSAGE (NCT05644951)
- Testing
- Hot AXIOS system used for EPASS
- Where
- 6 sites in Japan
- Volunteers
- 51 people
- Sponsor
- Boston Scientific Corporation
Malignant Biliary Obstruction
PROceeding With Advanced Techniques in Case of Distal Malignant Biliary Obstruction and Difficult Biliary Cannulation comparEd With Therapeutic-EUS: the PROMETHEUS Trial
Endoscopic retrograde cholangiopancreatography (ERCP) stands as the primary approach for addressing jaundice in individuals with distal malignant biliary obstruction.
- Trial name
- PROMETHEUS (NCT06550973)
- Testing
- pre-cut biliary sphincterotomy/fistulotomy, double guide wire (DGW) technique
- Volunteers
- 220 people
- Sponsor
- Istituto Clinico Humanitas
Pancreatic Adenocarcinoma
Contrast-harmonic Endoscopic Ultrasound (CH-EUS) for the Diagnosis of Pancreatic Adenocarcinoma
Ductal adenocarcinoma is the most frequent pancreatic solid lesion and the most common tumor of the pancreas. Given its poor prognosis and the major therapeutic consequences, the discrimination between PA and other pancreatic…
- Trial name
- NCT01765036
- Testing
- SonoVue®
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Société Française d'Endoscopie Digestive
Endoscopic Ultrasonography, Pancreatic Disease
Validation of an AI-based Biliopancreatic EUS Navigation System for Real-time Quality Improvement: A Prospective, Single-center, Randomized Controlled Trial
Endoscopic ultrasonography (EUS) is a key procedure for diagnosing biliopancreatic diseases. However, the performance among EUS endoscopists varies greatly and leads to blind areas during operation, which impaired the health…
- Conditions
- Endoscopic Ultrasonography, Pancreatic Disease, Bile Duct Diseases, Artificial Intelligence
- Trial name
- NCT05457101
- Testing
- AI-based biliopancreatic EUS navigation system
- Where
- China
- Volunteers
- 264 people, healthy volunteers welcome
- Sponsor
- Renmin Hospital of Wuhan University
Cholangiocarcinoma, Pancreatic Cancer
T-EUS for Gastrointestinal Disorders: A Multicenter Registry
The purpose of this registry is to record information and evaluate the impact of Endoscopic Ultrasound (EUS) Guided Endoscopic retrograde cholangiopancreatography (ERCP) on the management of pancreatico-biliary disorders.
- Conditions
- Cholangiocarcinoma, Pancreatic Cancer, Bile Duct Cancer, Biliary Stricture
- Trial name
- EUSERCPReg (NCT01522573)
- Testing
- EUS guided ERCP
- Where
- 2 sites in United States, Brazil
- Volunteers
- 1,000 people
- Sponsor
- Weill Medical College of Cornell University
Walled-off Necrosis
Comparing Fully Covered, Self Expanding Metal Stent (FCSEMS) and Plastic Stents for EUS- Guided Drainage of WON
This is a multi-center, single-blinded, randomized trial comparing AXIOS FCSEMS (Fully Covered Self Expanding Metal Stent) and plastic stents for EUS (Endoscopic Ultrasound)-guided management of infected and/or symptomatic WON…
- Trial name
- WON (NCT02718092)
- Testing
- Plastic Stent, Axios Fully Covered Self Expanding Metal Stent
- Sponsor
- Indiana University
Anesthesia, Airway Device
Laryngeal Mask in Upper Gastrointestinal Procedures
Diagnostic and operative procedures of upper gastrointestinal (GI) tract are very common in all patients. Some procedures are difficult to tolerate because of long duration, prone position or significant stimulation of the upper…
- Conditions
- Anesthesia, Airway Device, C.Surgical Procedure; Gastrointestinal
- Trial name
- SeoMask (NCT03567928)
- Testing
- Sedation with Gastro Cuff Pilot Laryngeal Mask, Propofol
- Where
- Italy
- Volunteers
- 16 people
- Sponsor
- Ospedale San Raffaele
ENDOSCOPIC ULTRASONOGRAPHY
COMPARISON OF OUTCOMES OF BI-FLANGED METAL STENT ALONE VERSUS BI-FLANGED METAL STENT WITH CO-AXIAL PLASTIC STENT FOR DRAINAGE OF WALLED-OFF PANCREATIC NECROSIS - A PROSPECTIVE RANDOMISED CONTROLLED STUDY.
Endoscopic ultrasound guided drainage of WON with metal stent is the mainstay of WON management. But there are few complications related to BFMS , like bleeding due to vessel erosion, stent clogging , stent migration .
- Trial name
- BFMSP (NCT05632900)
- Testing
- Endoscopic ultrasound guided drainage of walled off pancreatic necrosis
- Where
- India
- Volunteers
- 76 people
- Sponsor
- Asian Institute of Gastroenterology, India
Pancreatic Ductal Adenocarcinoma
EUS-RFA for Unresectable Pancreatic Cancer
The clinical application of intraoperative or percutaneous radiofrequency ablation (RFA) for pancreatic ductal adenocarcinoma (PDAC) is limited due to higher mortality and incidence of adverse events.
- Trial name
- NCT04310111
- Testing
- EUS-RFA
- Where
- China
- Volunteers
- 8 people
- Sponsor
- First People's Hospital of Hangzhou
Acute Cholecystitis
EUS-GBD vs Antibiotics for Patients at High Risk for Cholecystectomy
Objectives Acute cholecystitis commonly occurs in elderly patients who are at high-risk for surgery. Whether upfront Endoscopic ultrasound-guided gallbladder drainage (EUS-GBD) is advantageous over antibiotics first for mild…
- Trial name
- NCT05893511
- Testing
- Endoscopic ultrasound-guided gallbladder drainage, Antibiotics first
- Where
- Hong Kong
- Volunteers
- 110 people
- Sponsor
- Chinese University of Hong Kong
Pain, Pancreatic Cancer
Endoscopic Ultrasound (EUS) Guided-Celiac Plexus Neurolysis (CPN) in Unresectable Pancreatic Cancer
The purpose of this study is to examine endoscopic ultrasound guided celiac plexus neurolysis (CPN) with analgesic therapy in patients with unresectable pancreatic cancer as it applies to decreasing the severity of abdominal pain…
- Trial name
- NCT00968175
- Testing
- Ultrasound guided celiac plexus neurolysis (CPN)
- Where
- 2 sites in United States
- Volunteers
- 60 people
- Sponsor
- University of Alabama at Birmingham