Clinical trials: EUS
Biliary Pancreatitis
Impact on Outcome of Early Endoscopic Extraction of Bile Duct Stones in Biliary Pancreatitis
Impact on outcome of early endoscopic extraction of bile duct stones in biliary pancreatitis: a prospective multicenter randomized controlled study.
- Trial name
- EEPAB (NCT00505128)
- Testing
- Endoscopic sphincterotomy
- Where
- France
- Volunteers
- 900 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Pancreas Neoplasm, Pancreatitis
EUS Shear Wave for Solid Pancreatic Lesions.
The diagnosis of pancreas diseases is based on a combination of clinical signs, symptoms, and laboratory tests, but mainly on imaging techniques such as computed tomography (CT) and magnetic resonance (MR).
- Conditions
- Pancreas Neoplasm, Pancreatitis, Pancreatitis, Acute, Pancreatitis, Chronic
- Trial name
- NCT05095831
- Testing
- Pancreas EUS shear wave, Pancreas EUS-elastography and EUS-guided biopsy
- Where
- Ecuador
- Volunteers
- 25 people
- Sponsor
- Instituto Ecuatoriano de Enfermedades Digestivas
Gastric Outlet Obstruction Due to Malignancy, EUS Guided Enteroenteric Anastomosis
Outcome of Patients With Malignant Gastric Outlet Obstruction Undergoing Endoscopic Ultrasound-guided Gastroenterostomy or Enteral Metal Stenting
Gastric outlet obstruction (GOO) refers to a mechanical blockage of the distal stomach or duodenum that prevents normal passage of food and liquids.
- Conditions
- Gastric Outlet Obstruction Due to Malignancy, EUS Guided Enteroenteric Anastomosis, Endoscopy, Digestive System
- Trial name
- NCT07230665
- Testing
- Endoscopic ultrasound-guided gastroenterostomy
- Where
- Taiwan
- Volunteers
- 200 people
- Sponsor
- National Taiwan University Hospital
Pancreatic Cancer
Evaluation of MMR Status and PD-L1 Expression Using Specimens Obtained by EUS-FNB in Patients With Pancreatic Cancer
Pancreatic ductal adenocarcinoma (PDAC) has a suboptimal response to standard therapies that modestly impact survival due to its ability to evade host immune surveillance.
- Trial name
- SUCCESS (NCT03820921)
- Testing
- EUS-FNB, Immunohistochemistry
- Volunteers
- 30 people
- Sponsor
- Ponderas Academic Hospital
Malignant Biliary Obstruction
RIVOS Feasibility (MBO)
The goal of this clinical trial is to assess basic feasibility, safety, and performance of an EUS access device in patients with malignant biliary obstruction who are indicated to receive EUS-guided hepaticogastrostomy for…
- Trial name
- NCT06666699
- Testing
- EUS access device
- Where
- 3 sites in Belgium, France and 1 more
- Sponsor
- Boston Scientific Corporation
Cholecystitis, Acute, Cholecystitis; Gallstone
Observation vs Early Removal of LAMS in EUS Guided Cholecystoenterostomy
The study will compare the outcomes of patients with gallstone related cholecystitis who are poor surgical candidates undergoing EUS guided cholecystoenterostomy via a lumen apposing metal stent (LAMS).
- Trial name
- NCT04167072
- Testing
- Stent removal
- Where
- United States
- Sponsor
- Texas Tech University Health Sciences Center, El Paso
Lymph Nodes, Esophageal Cancer
Interobserver Agreement of Endoscopic Ultrasonography and Endoscopic Sonoelastography in the Evaluation of Lymph Nodes
Endoscopic ultrasound (EUS) is an important part of the pre-treatment evaluation of patients with upper gastrointestinal tract cancer (esophageal, gastric, pancreatic and liver cancer).
- Conditions
- Lymph Nodes, Esophageal Cancer, Gastric Cancer, Pancreatic Cancer
- Trial name
- NCT01033695
- Where
- Denmark
- Volunteers
- 74 people
- Sponsor
- Odense University Hospital
Portal Pressure Gradient (PPG) Measurement Guided by Endoscopic Ultrasound (EUS), Left Lateral Decubitus
Left Lateral Position and Supine Position in EUS-PPG Measurement
The consistency of EUS-PPG measurements between left lateral decubitus and supine positions is unclear. In this prospective comparative study, we are aimed to evaluate the correlation between EUS-PPG measured in supine position…
- Trial name
- NCT06994039
- Testing
- EUS-lePPG
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Pancreatic Cancer, Endoscopy
Plastic Stent Within a Lumen-Apposing Stent for Malignant Biliary Obstruction
There are doubts concerning the possible benefits derived from the insertion of double-pigtail plastic stents (DPS) within the lumen-apposing metal stents (LAMS) in the EUS-guided transmural biliary drainage (BD).
- Conditions
- Pancreatic Cancer, Endoscopy, Oncologic Disorders, Therapy Related Neoplasms
- Trial name
- LAMSpigBil (NCT04420039)
- Testing
- Endoscopic biliary transmural drainage
- Where
- 3 sites in Spain
- Volunteers
- 39 people
- Sponsor
- Hospital Universitari de Bellvitge
Malignant Biliary Stricture
Endoscopic Biliary Drainage in Malignant High Grade Biliary Stricture
Biliary drainage is the mainstay of the palliative treatment in patients with inoperable malignant bile duct stricture. Endoscopic retrograde cholangiopancreatography (ERCP) is the cornerstone of biliary drainage method in these…
- Trial name
- NCT03530527
- Testing
- ERCP with biliary stenting, EUS guided biliary drainage
- Where
- 2 sites in Thailand
- Volunteers
- 10 people
- Sponsor
- Prince of Songkla University
Pancreatic Cancer
Application of Newly Developed Endoscopic Ultrasound With Zone Sonography Technology for Diagnosis of Pancreatic Caner
The purpose of this study is to measure and compare the difference of sound speed between pancreatic cancer and non-pancreatic cancer, and determine the critical value of sound speed for benign and malignant pancreatic cancer.
- Trial name
- NCT03933111
- Testing
- local sound velocity measurement
- Where
- China
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Abnormal Liver Function
Comparison of 19g FNA and 19g FNB Needles for EUS-LB
Chronic liver disorders (CLD) are a major cause of morbidity and mortality for individuals in the US. Though serologic analysis will often lead to a conclusive diagnosis, liver biopsy remains an important method for helping to…
- Trial name
- NCT03408171
- Testing
- 19-gauge FNA needle, 19-gauge FNB needle
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Geisinger Clinic
Pancreatic Cystic Lesions
Evaluation of PCLs Using Three EUS-FNA Needles
To document impact of EUS-FNA needle size and flexibility on effectiveness of pancreatic cystic lesions (PCL) aspiration, on ability to obtain sufficient material for standard diagnostic testing, and on diagnostic accuracy of…
- Trial name
- NCT01711294
- Testing
- 19 G Flex Needle, 22 G Needle, 19 G Needle
- Where
- 8 sites in United States, China and 1 more
- Volunteers
- 250 people
- Sponsor
- Boston Scientific Corporation
Patients Undergoing Endoscopic Ultrasound
Electroacupuncture Analgesia for EUS: a Randomized Controlled Trial
Endoscopic ultrasound (EUS) has evolved to become an important diagnostic tool and its interventional role is rapidly expanding.
- Trial name
- NCT02066194
- Testing
- Electroacupuncture
- Where
- Hong Kong
- Volunteers
- 128 people
- Sponsor
- Chinese University of Hong Kong
Pancreatic Neoplasms, Pancreatic Cancer
On-site Cytopathology EUS-FNA
This study is a multicenter prospective randomized controlled trial. Potential participants in this study include patients referred for Endoscopic Ultrasound-guided fine needle aspiration (EUS-FNA) of a solid pancreatic lesion at…
- Trial name
- NCT01386931
- Testing
- EUS-guided FNA performed with on-site Cytopathologist, EUS-guided FNA performed without on-site Cytopathologist
- Where
- United States
- Volunteers
- 111 people
- Sponsor
- University of Colorado, Denver
Submucosal Tumor of Gastrointestinal Tract
Diagnostic Accuracy of SurePath™ in EUS-FNA
It is a prospective randomized controlled study to evaluate the diagnostic accuracy of SurePath™ liquid-based cytology in endoscopic ultrasound-guided sampling.
- Trial name
- NCT05394129
- Testing
- SurePath™
- Where
- South Korea
- Volunteers
- 89 people
- Sponsor
- Seoul National University Hospital
Alcoholism, Cirrhosis
Acoustic Liver Biopsy in Normals and in Patients With Cirrhosis Using Endoscopic Ultrasound
The purpose of this study is to determine the amount of fibrosis in the liver of hepatitis C patients with advanced fibrosis, using endoscopic ultrasound.
- Conditions
- Alcoholism, Cirrhosis, Hepatitis c
- Trial name
- NCT01208311
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Pancreatic Tumor
Head to Head Comparison of Two Needles EUS Guided FNB
The aim of this study is to evaluate and compare the diagnostic accuracy and specimen adequacy of two ultrasound biopsy needles.
- Trial name
- NCT02534246
- Testing
- Ultrasound biopsy needle Echo Tip ProCore, Ultrasound biopsy needle SharkCore
- Where
- United States
- Sponsor
- Milton S. Hershey Medical Center
Chronic Liver Disease (CLD), Liver Fibrosis
Correlation Of EUS-SWQ And Liver Fibrosis Pathology In Chronic Liver Disease
The goal of this clinical study is to learn whether the Olympus EU-ME3 endoscopic ultrasound shear wave quantification (EUS-SWQ) function can accurately diagnose and grade liver fibrosis in patients with chronic liver disease.
- Trial name
- EUS-SWQ-202601 (NCT07588854)
- Where
- China
- Volunteers
- 65 people
- Sponsor
- Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
GI Lesions
Endoscopic Ultrasound (EUS) Fine Needle Biopsy (FNB) Submucosal Nodule
The purpose of this study is to compare the diagnostic accuracy of a novel endoscopic ultrasound (EUS) biopsy needle to the current standard EUS needle.
- Trial name
- NCT03011229
- Testing
- Pro Core Needle, medtronic Sharkcore Needle
- Where
- United States
- Sponsor
- Duke University