Clinical trials: EUS
Endoscopic Ultrasonography, Artificial Intelligence
To Evaluate the Capability of an EUS Automatic Image Reporting System
In this study, the EUS intelligent picture reporting system can automatically generate reports after reading videos of EUS examinations.
- Trial name
- NCT05858827
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Renmin Hospital of Wuhan University
Common Bile Duct Calculi
The Cost Effectiveness of Endoscopic Ultrasound ( EUS ) Based Strategy in Diagnosis of Common Bile Duct Stones
Multiple reports in the literature showed the efficacy of EUS comparable to ERCP in the diagnosis of common bile duct ( CBD ) stone.
- Trial name
- NCT02349568
- Testing
- High risk group, Intermediate risk group
- Where
- Thailand
- Volunteers
- 141 people
- Sponsor
- Prince of Songkla University
Non Functioning Pancreatic Endocrine Tumor
Diagnostic Accuracy of Preoperative Diagnostic Procedure in the Assessment of Lymph Node Metastases by NF-PanNENs
Pancreatic Neuroendocrine Neoplasms (PanNEN) are a heterogeneous group of neoplasms that arise from the endocrine cells of the pancreatic gland.
- Trial name
- NCT03918759
- Where
- Italy
- Volunteers
- 100 people
- Sponsor
- IRCCS San Raffaele
Pancreatic Cancer
EUS-guided Celiac Plexus Neurolysis for the Treatment of Abdominal Pain in Pancreatic Cancer
Studies have shown that injecting local anesthetics in areas rich in blood vessels increases the risk of drug injection into blood vessels by mistake and increases the systemic absorption of drugs, which may increase the…
- Trial name
- NCT03940027
- Testing
- EUS-guided celiac plexus neurolysis
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Changhai Hospital
Pancreatic Mucinous-Cystic Neoplasm
Endoscopic Ultrasonography-guided Double Ethanol Lavage for Pancreatic Cysts: a Prospective Cohort Study
Due to widespread use of cross-sectional imaging modalities, pancreatic cysts are common in abdominal image. These lesions encompass a wide spectrum, ranging from benign to malignant.
- Trial name
- NCT02213419
- Testing
- Endoscopic ultrasonography-guided double ethanol lavage
- Where
- South Korea
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samsung Medical Center
Non-alcoholic Steatohepatitis (NASH), Endoscopic Sleeve Gastroplasty
A Physiologic Analysis of Endoscopic Sleeve Gastroplasty (ESG)
Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease worldwide. Affecting approximately one-third of the United States (U.S.) population, the prevalence of NAFLD increases to 90% in patients with…
- Conditions
- Non-alcoholic Steatohepatitis (NASH), Endoscopic Sleeve Gastroplasty, Non-alcoholic Fatty Liver Disease (NAFLD), Endoscopic Ultrasound
- Trial name
- NCT04820036
- Testing
- Insulin Resistance, Quality of Life Assessment, Liver Function Test
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Brigham and Women's Hospital
Malignant Biliary Obstruction, Biliary Tract Neoplasms
EUS-Gallbladder vs CDS as First Line in MBDO- Palliative (CARPEGIEM Trial)
The aim of the study is to evaluate technical, clinical and safety outcomes of lumen-apposing metal stent (LAMS) with a coaxial double-pigtail plastic stent (DPS) in EUS-guided choledochoduodenostomies vs cholcystogastrostomy for…
- Conditions
- Malignant Biliary Obstruction, Biliary Tract Neoplasms, Pancreatic Cancer Non-resectable
- Trial name
- CARPEGIEM (NCT06375967)
- Testing
- Endoscopic biliary drainage, Lumen-apposing metal stent (LAMS) and double-pigtail plastic stent (DPPS)
- Where
- 10 sites in Spain
- Volunteers
- 128 people
- Sponsor
- Hospital Universitari de Bellvitge
Tumor Appearance of Biliary System Obstruction
Prospective Study Comparing EUS vs ERCP Stent Insertion for Malignant Biliary Obstruction
1. Purpose of the study -To compare stent patency and complication rate between endoscopic ultrasound (EUS) guided stent insertion and endoscopic retrograde cholangiopancreatography (ERCP) guided stent insertion for malignant…
- Trial name
- NCT01421836
- Testing
- ERCP-guided stent insertion, EUS guided stent insertion
- Where
- South Korea
- Volunteers
- 30 people
- Sponsor
- Samsung Medical Center
Portal Pressure Gradient (PPG) Measurement Guided by Endoscopic Ultrasound (EUS), Hepatic Cirrhosis
Evaluation of the Efficacy and Safety of Portal Pressure Gradient (PPG) Measurement Guided by Endoscopic Ultrasound (EUS) in the Therapeutic Algorithm of Patients with Liver Cirrhosis.
The development of Clinical significant PH (CSPH) is a major driver of complications. PPG is the strongest predictor of decompensation .
- Trial name
- GPP-USE (NCT06664307)
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Hospital Universitario Virgen Macarena
Pancreatic Ductal Adenocarcinoma
A Clinical Study of EUS-RFA for Inoperable Pancreatic Ductal Adenocarcinoma
To assess if endoscopic ultrasound-guided radiofrequency ablation application in patients with inoperable pancreatic cancer confers survival benefit when compared to patients receiving standard medical care.
- Trial name
- EUS-RFA (NCT03444948)
- Testing
- EUS-RFA using Habib Tm as a probe, EUS
- Where
- Canada
- Volunteers
- 108 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Esophageal Cancer, Stomach Cancer
EUFURO - EUS-based Follow-Up on R0-resected Patients for Esophageal, Gastric and Pancreatic Cancer
Follow-up after successful operative treatment of cancer in the esophagus, stomach or pancreas in order to detect recurrent disease is a controversial topic.
- Conditions
- Esophageal Cancer, Stomach Cancer, Pancreatic Cancer
- Trial name
- EUFURO (NCT02209415)
- Testing
- standard follow-up, PET/CT and EUS
- Where
- Denmark
- Volunteers
- 182 people
- Sponsor
- Michael Bau Mortensen
Metastatic Pancreatic Cancer
Implantation of iodine125-Seeds Combined With Chemotherapy in the Treatment of Metastatic Pancreatic Carcinoma
The goal of this clinical trial is to evaluate the clinical efficacy and safety of endoscopic ultrasonography (EUS)-guided radioactive iodine 125 seeds in combination with AG regimen chemotherapy for the treatment of metastatic…
- Trial name
- NCT05869474
- Testing
- Iodine125-Seeds implantation, Gem/nab-P Chemotherapy
- Where
- China
- Volunteers
- 206 people
- Sponsor
- Changhai Hospital
Acute Biliary Pancreatitis
Early EUS in Acute Biliary Pancreatitis
Acute biliary pancreatitis (ABP) is a potentially life-threatening condition caused by common bile duct (CBD) stones or sludge, which requires prompt diagnosis and treatment by endoscopic removal of the material.
- Trial name
- NCT02430285
- Testing
- Endoscopic Ultrasound, Olympus 180 series echoendoscope
- Where
- Italy
- Volunteers
- 181 people
- Sponsor
- Istituto Clinico Humanitas
RFA, Microwave Ablation
EUS-Guided Ablation (RFA and MWA) for Pancreatic and Other Gastrointestinal Lesions Registry
This is a single-center, investigator-initiated, prospective observational registry that will collect longitudinal clinical data on adult patients (≥18 years) undergoing endoscopic ultrasound (EUS)-guided radiofrequency ablation…
- Conditions
- RFA, Microwave Ablation, Pancreatic Lesion, Gastrointestinal Lesions
- Trial name
- NCT07625189
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- West Virginia University
Chronic Pancreatitis
Endoscopic Ultrasound-Guided Celiac Plexus Neurolysis (EUS-CPN) for Chronic Pancreatitis
Physicians need a tracking system for specific treatment modalities, and data to determine the impact of endoscopic ultrasound pain management for patients with chronic pancreatitis.
- Trial name
- CPN (NCT04403074)
- Testing
- Celiac Plexus Neurolysis
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Indiana University
Siewert Type I-II Adenocarcinoma of the Esophagus
Siewert Type I-II: CT, PET-CT, EUS Sensitivity/Specificity for the Assessment of Lymph Node Metastases
In Siewert type I/II EAC, sensitivity/specificity of CT, PET-CT, EUS for assessment of N descriptor in defined groups of lymph nodes were investigated.
- Trial name
- ADECC2-2017 (NCT03529968)
- Testing
- esophagectomy
- Where
- Italy
- Volunteers
- 101 people
- Sponsor
- University of Bologna
Acute Cholecystitis
Conservative Versus Proactive Management of Acute Cholecystitis After EUS-guided Transmural Gallbladder Drainage: FUGITIVE Trial (FUGITIVE)
Patients with gallbladder inflammation (acute cholecystitis) who cannot undergo surgery due to their fragility and surgical risk require a gallbladder drainage.
- Trial name
- FUGITIVE (NCT06967597)
- Testing
- Cholecystoscopy and gallbladder cleaning
- Where
- 2 sites in Spain
- Volunteers
- 82 people
- Sponsor
- Hospital General Universitario de Alicante
Suspected Bilio-pancreatic Disease
Magnetic Resonance Cholangio-pancreatography (MRCP) for Suspected Bilio-pancreatic Disease
The interpretation of Magnetic Resonance Cholangio-pancreatography (MRCP)-findings is primarily performed by radiologists who only in some cases have experience with the interpretation of endoscopic retrograde…
- Trial name
- NCT01538368
- Volunteers
- 155 people
- Sponsor
- Deutsche Klinik fuer Diagnostik
Solid Lesion Biopsies
Study Comparing 25d ProCor Needle Versus the Standard 25g Needle for Biopsies Performed by EUS-FNA
Background: There is an ongoing interest in developing Endoscopic Ultrasound /Fine Needle Aspiration (EUS-FNA) needles that can provide tissue core biopsies for a true histological (rather than cytological) evaluation.
- Trial name
- NCT02048124
- Testing
- 25g standard needle, 25d ProCor needle
- Where
- Canada
- Volunteers
- 224 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Pancreatic or Peripancreatic Lesions, Lesions in the Esophagus, Stomach, Duodenum or Rectum
The Cellularity Yield of Three Different 22-gauge FNA Needles
Obtaining a sample from a lesion in the gastrointestinal tract by endoscopic ultrasound (a flexible tube with a camera and small ultrasound machine at its end )requires the use of a needle for taking the sample from the lesion or…
- Conditions
- Pancreatic or Peripancreatic Lesions, Lesions in the Esophagus, Stomach, Duodenum or Rectum, Mediastinal ( Chest) Masses, Enlarged Lymph Nodes
- Trial name
- NCT01916421
- Testing
- Endoscopic Ultrasound Fine Needle Aspiration (EUS-FNA)
- Where
- United States
- Volunteers
- 107 people
- Sponsor
- Texas Tech University Health Sciences Center, El Paso